{"id":"https://openalex.org/W2769923075","doi":null,"title":"Investigating retinal pathology in patients carrying m.3243A>G mutation using human induced pluripotent stem cells","display_name":"Investigating retinal pathology in patients carrying m.3243A>G mutation using human induced pluripotent stem cells","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2769923075","mag":"2769923075"},"language":"en","primary_location":{"id":"mag:2769923075","doi":null,"is_oa":false,"landing_page_url":"https://theses.ncl.ac.uk/jspui/bitstream/10443/3652/1/Chichagova%2c%20V.%202017.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024873019","display_name":"Valeria Chichagova","orcid":"https://orcid.org/0000-0002-7289-3640","observed_orcids":["https://orcid.org/0000-0002-7289-3640"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Valeria Chichagova","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7289-3640","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5024873019"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.006599999964237213,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/m-3243a-g-mutation","display_name":"m.3243A>G mutation","score":0.9350000023841858},{"id":"https://openalex.org/keywords/mtdna-mutations","display_name":"mitochondrial DNA mutations","score":0.5550000071525574},{"id":"https://openalex.org/keywords/retinal-disease","display_name":"retinal disease","score":0.824999988079071},{"id":"https://openalex.org/keywords/retinitis-pigmentosa","display_name":"retinitis pigmentosa","score":0.7630000114440918},{"id":"https://openalex.org/keywords/human-induced-pluripotent-stem-cells","display_name":"human induced pluripotent stem cells","score":0.8999999761581421},{"id":"https://openalex.org/keywords/mitochondrial-disease","display_name":"mitochondrial disease","score":0.8240000009536743}],"concepts":[{"id":"https://openalex.org/C107459253","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Induced pluripotent stem cell","level":4,"score":0.7819839715957642},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5520947575569153},{"id":"https://openalex.org/C2910924664","wikidata":"https://www.wikidata.org/wiki/Q674925","display_name":"Human Induced Pluripotent Stem Cells","level":5,"score":0.5275440216064453},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5231990814208984},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.47662127017974854},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4510591924190521},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.40109366178512573},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3782610297203064},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3294711709022522},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.2519962787628174},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.2226085364818573},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18546780943870544}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2769923075","doi":null,"is_oa":false,"landing_page_url":"https://theses.ncl.ac.uk/jspui/bitstream/10443/3652/1/Chichagova%2c%20V.%202017.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":302,"referenced_works":["https://openalex.org/W45416255","https://openalex.org/W144423133","https://openalex.org/W269249036","https://openalex.org/W356590450","https://openalex.org/W584034722","https://openalex.org/W1262221686","https://openalex.org/W1489968410","https://openalex.org/W1494201811","https://openalex.org/W1498308778","https://openalex.org/W1505418232","https://openalex.org/W1507327514","https://openalex.org/W1517158798","https://openalex.org/W1518310590","https://openalex.org/W1522323234","https://openalex.org/W1528120845","https://openalex.org/W1534717671","https://openalex.org/W1568406795","https://openalex.org/W1569904835","https://openalex.org/W1589588578","https://openalex.org/W1599485077","https://openalex.org/W1603508604","https://openalex.org/W1628572451","https://openalex.org/W1645300466","https://openalex.org/W1658577344","https://openalex.org/W1790985176","https://openalex.org/W1925859338","https://openalex.org/W1938352236","https://openalex.org/W1943906773","https://openalex.org/W1953804216","https://openalex.org/W1954748650","https://openalex.org/W1964081206","https://openalex.org/W1964936056","https://openalex.org/W1965319690","https://openalex.org/W1966300591","https://openalex.org/W1966986920","https://openalex.org/W1967025085","https://openalex.org/W1967136141","https://openalex.org/W1967304767","https://openalex.org/W1968622987","https://openalex.org/W1969331809","https://openalex.org/W1970894097","https://openalex.org/W1971453554","https://openalex.org/W1971649501","https://openalex.org/W1972100019","https://openalex.org/W1972334415","https://openalex.org/W1972476228","https://openalex.org/W1973470396","https://openalex.org/W1974012180","https://openalex.org/W1974644062","https://openalex.org/W1975239156","https://openalex.org/W1975369096","https://openalex.org/W1976690565","https://openalex.org/W1977174816","https://openalex.org/W1977493775","https://openalex.org/W1977545536","https://openalex.org/W1978437552","https://openalex.org/W1980243879","https://openalex.org/W1980333061","https://openalex.org/W1980608195","https://openalex.org/W1981088384","https://openalex.org/W1983847076","https://openalex.org/W1985263934","https://openalex.org/W1985775217","https://openalex.org/W1986940374","https://openalex.org/W1987713800","https://openalex.org/W1987770475","https://openalex.org/W1988280121","https://openalex.org/W1989920563","https://openalex.org/W1990289864","https://openalex.org/W1991037959","https://openalex.org/W1991250133","https://openalex.org/W1992091494","https://openalex.org/W1992525863","https://openalex.org/W1994009311","https://openalex.org/W1994133882","https://openalex.org/W1995732106","https://openalex.org/W1997209262","https://openalex.org/W1999444078","https://openalex.org/W2001503236","https://openalex.org/W2002943691","https://openalex.org/W2003935383","https://openalex.org/W2004211510","https://openalex.org/W2004280138","https://openalex.org/W2005033621","https://openalex.org/W2005487633","https://openalex.org/W2007014682","https://openalex.org/W2008905720","https://openalex.org/W2010249931","https://openalex.org/W2010298858","https://openalex.org/W2010672807","https://openalex.org/W2010817494","https://openalex.org/W2013304964","https://openalex.org/W2016442331","https://openalex.org/W2017347785","https://openalex.org/W2017561689","https://openalex.org/W2018113993","https://openalex.org/W2018217184","https://openalex.org/W2019019085","https://openalex.org/W2020423861","https://openalex.org/W2021124272","https://openalex.org/W2021234912","https://openalex.org/W2022489847","https://openalex.org/W2023327872","https://openalex.org/W2024530489","https://openalex.org/W2025387875","https://openalex.org/W2027225113","https://openalex.org/W2027833338","https://openalex.org/W2030211860","https://openalex.org/W2030535403","https://openalex.org/W2030562257","https://openalex.org/W2031468048","https://openalex.org/W2033719428","https://openalex.org/W2035121417","https://openalex.org/W2035824400","https://openalex.org/W2036229829","https://openalex.org/W2036632122","https://openalex.org/W2036823768","https://openalex.org/W2037204981","https://openalex.org/W2037338370","https://openalex.org/W2038106981","https://openalex.org/W2039279873","https://openalex.org/W2039914603","https://openalex.org/W2040421038","https://openalex.org/W2040434386","https://openalex.org/W2041255419","https://openalex.org/W2042965442","https://openalex.org/W2043015105","https://openalex.org/W2044488811","https://openalex.org/W2044877927","https://openalex.org/W2044897807","https://openalex.org/W2044939573","https://openalex.org/W2045134801","https://openalex.org/W2045684086","https://openalex.org/W2045731328","https://openalex.org/W2045859114","https://openalex.org/W2045899482","https://openalex.org/W2046304535","https://openalex.org/W2047015004","https://openalex.org/W2047213214","https://openalex.org/W2048554758","https://openalex.org/W2049176786","https://openalex.org/W2049358079","https://openalex.org/W2050160133","https://openalex.org/W2050254109","https://openalex.org/W2051937183","https://openalex.org/W2053114086","https://openalex.org/W2053153356","https://openalex.org/W2057159461","https://openalex.org/W2057250698","https://openalex.org/W2057962047","https://openalex.org/W2058607314","https://openalex.org/W2058906042","https://openalex.org/W2059282884","https://openalex.org/W2059353571","https://openalex.org/W2060613703","https://openalex.org/W2060849203","https://openalex.org/W2061004792","https://openalex.org/W2061586889","https://openalex.org/W2064080426","https://openalex.org/W2064670731","https://openalex.org/W2066413879","https://openalex.org/W2067091330","https://openalex.org/W2071118353","https://openalex.org/W2071466648","https://openalex.org/W2072239613","https://openalex.org/W2073377349","https://openalex.org/W2073947789","https://openalex.org/W2074314696","https://openalex.org/W2074498796","https://openalex.org/W2074744546","https://openalex.org/W2076194888","https://openalex.org/W2076693703","https://openalex.org/W2077670728","https://openalex.org/W2078201066","https://openalex.org/W2079855250","https://openalex.org/W2081163107","https://openalex.org/W2081233800","https://openalex.org/W2082211576","https://openalex.org/W2082682623","https://openalex.org/W2082933486","https://openalex.org/W2083062636","https://openalex.org/W2083178253","https://openalex.org/W2083560313","https://openalex.org/W2084201375","https://openalex.org/W2084299658","https://openalex.org/W2084969545","https://openalex.org/W2085979052","https://openalex.org/W2086663462","https://openalex.org/W2086943348","https://openalex.org/W2087777915","https://openalex.org/W2087786585","https://openalex.org/W2088088839","https://openalex.org/W2088112980","https://openalex.org/W2088152986","https://openalex.org/W2088828702","https://openalex.org/W2088995367","https://openalex.org/W2091296592","https://openalex.org/W2091315047","https://openalex.org/W2092167465","https://openalex.org/W2092305238","https://openalex.org/W2093724972","https://openalex.org/W2093888082","https://openalex.org/W2094971722","https://openalex.org/W2095058526","https://openalex.org/W2095251357","https://openalex.org/W2095566500","https://openalex.org/W2098124212","https://openalex.org/W2098597036","https://openalex.org/W2099313405","https://openalex.org/W2101656247","https://openalex.org/W2105465142","https://openalex.org/W2105592350","https://openalex.org/W2106336456","https://openalex.org/W2107060734","https://openalex.org/W2108372345","https://openalex.org/W2108547322","https://openalex.org/W2108931314","https://openalex.org/W2109291482","https://openalex.org/W2109583860","https://openalex.org/W2110208429","https://openalex.org/W2112156060","https://openalex.org/W2113415712","https://openalex.org/W2114914263","https://openalex.org/W2115281784","https://openalex.org/W2117567932","https://openalex.org/W2120288525","https://openalex.org/W2121104839","https://openalex.org/W2123779991","https://openalex.org/W2124760311","https://openalex.org/W2125928172","https://openalex.org/W2126851387","https://openalex.org/W2126929503","https://openalex.org/W2130519358","https://openalex.org/W2130576009","https://openalex.org/W2131434664","https://openalex.org/W2134846845","https://openalex.org/W2135869155","https://openalex.org/W2136609330","https://openalex.org/W2138088258","https://openalex.org/W2138558536","https://openalex.org/W2138977668","https://openalex.org/W2139103260","https://openalex.org/W2139425600","https://openalex.org/W2141856502","https://openalex.org/W2142046859","https://openalex.org/W2142486785","https://openalex.org/W2144342124","https://openalex.org/W2144600588","https://openalex.org/W2145233689","https://openalex.org/W2146078700","https://openalex.org/W2146606376","https://openalex.org/W2147284744","https://openalex.org/W2148828403","https://openalex.org/W2149429457","https://openalex.org/W2149968101","https://openalex.org/W2150163104","https://openalex.org/W2151040450","https://openalex.org/W2152483372","https://openalex.org/W2153149309","https://openalex.org/W2153478200","https://openalex.org/W2153824299","https://openalex.org/W2154599811","https://openalex.org/W2155579605","https://openalex.org/W2155734183","https://openalex.org/W2155786005","https://openalex.org/W2156411936","https://openalex.org/W2157635332","https://openalex.org/W2157741370","https://openalex.org/W2158414980","https://openalex.org/W2158780541","https://openalex.org/W2158994766","https://openalex.org/W2159561039","https://openalex.org/W2160288586","https://openalex.org/W2161489217","https://openalex.org/W2163404991","https://openalex.org/W2164174765","https://openalex.org/W2165838325","https://openalex.org/W2166131563","https://openalex.org/W2166295812","https://openalex.org/W2166550315","https://openalex.org/W2169187183","https://openalex.org/W2169961985","https://openalex.org/W2172916341","https://openalex.org/W2197714088","https://openalex.org/W2213373961","https://openalex.org/W2214361901","https://openalex.org/W2226963678","https://openalex.org/W2262938430","https://openalex.org/W2278006743","https://openalex.org/W2289166066","https://openalex.org/W2313474489","https://openalex.org/W2332419762","https://openalex.org/W2336853776","https://openalex.org/W2338125871","https://openalex.org/W2341577039","https://openalex.org/W2400226169","https://openalex.org/W2401140951","https://openalex.org/W2415418599","https://openalex.org/W2417491772","https://openalex.org/W2440415790","https://openalex.org/W2461263549","https://openalex.org/W2473778811"],"related_works":["https://openalex.org/W2752022773","https://openalex.org/W753739758","https://openalex.org/W2835102704","https://openalex.org/W3169001852","https://openalex.org/W2579573138","https://openalex.org/W3180839671","https://openalex.org/W2165112666","https://openalex.org/W4290829843","https://openalex.org/W2053114086","https://openalex.org/W2569528915"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2017-12-04T00:00:00"}
