{"id":"https://openalex.org/W2769737456","doi":"https://doi.org/10.15252/embj.201796918","title":"Histone methyltransferase SUV39H1 participates in host defense by methylating mycobacterial histone\u2010like protein HupB","display_name":"Histone methyltransferase SUV39H1 participates in host defense by methylating mycobacterial histone\u2010like protein HupB","publication_year":2017,"publication_date":"2017-11-23","ids":{"openalex":"https://openalex.org/W2769737456","doi":"https://doi.org/10.15252/embj.201796918","mag":"2769737456","pmid":"https://pubmed.ncbi.nlm.nih.gov/29170282","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5771397"},"language":"en","primary_location":{"id":"doi:10.15252/embj.201796918","doi":"https://doi.org/10.15252/embj.201796918","is_oa":true,"landing_page_url":"https://doi.org/10.15252/embj.201796918","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.201796918","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.201796918","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067391477","display_name":"Imtiyaz Yaseen","orcid":"https://orcid.org/0000-0001-9975-5785","observed_orcids":["https://orcid.org/0000-0001-9975-5785"]},"institutions":[{"id":"https://openalex.org/I164861460","display_name":"Manipal Academy of Higher Education","ror":"https://ror.org/02xzytt36","country_code":"IN","type":"education","lineage":["https://openalex.org/I164861460"]},{"id":"https://openalex.org/I78270026","display_name":"Centre for DNA Fingerprinting and Diagnostics","ror":"https://ror.org/04psbxy09","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I78270026"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Imtiyaz Yaseen","raw_affiliation_strings":["Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India","Graduate Studies, Manipal University, Manipal, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India","institution_ids":["https://openalex.org/I78270026"]},{"raw_affiliation_string":"Graduate Studies, Manipal University, Manipal, India","institution_ids":["https://openalex.org/I164861460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048564683","display_name":"Mitali Choudhury","orcid":"https://orcid.org/0000-0003-1754-4242","observed_orcids":["https://orcid.org/0000-0003-1754-4242"]},"institutions":[{"id":"https://openalex.org/I36893310","display_name":"University of Hyderabad","ror":"https://ror.org/04a7rxb17","country_code":"IN","type":"education","lineage":["https://openalex.org/I36893310"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mitali Choudhury","raw_affiliation_strings":["Department of Animal Biology, University of Hyderabad, Hyderabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Biology, University of Hyderabad, Hyderabad, India","institution_ids":["https://openalex.org/I36893310"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037096578","display_name":"Manjula Sritharan","orcid":"https://orcid.org/0000-0001-9873-2434","observed_orcids":["https://orcid.org/0000-0001-9873-2434"]},"institutions":[{"id":"https://openalex.org/I36893310","display_name":"University of Hyderabad","ror":"https://ror.org/04a7rxb17","country_code":"IN","type":"education","lineage":["https://openalex.org/I36893310"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manjula Sritharan","raw_affiliation_strings":["Department of Animal Biology, University of Hyderabad, Hyderabad, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Biology, University of Hyderabad, Hyderabad, India","institution_ids":["https://openalex.org/I36893310"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103050407","display_name":"Sanjeev Khosla","orcid":"https://orcid.org/0000-0002-7780-1813","observed_orcids":["https://orcid.org/0000-0002-7780-1813"]},"institutions":[{"id":"https://openalex.org/I78270026","display_name":"Centre for DNA Fingerprinting and Diagnostics","ror":"https://ror.org/04psbxy09","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I78270026"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Sanjeev Khosla","raw_affiliation_strings":["Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India sanjuk@cdfd.org.in","Centre for DNA Fingerprinting and Diagnostics (CDFD) Hyderabad India"],"raw_orcid":"https://orcid.org/0000-0002-7780-1813","affiliations":[{"raw_affiliation_string":"Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad, India sanjuk@cdfd.org.in","institution_ids":["https://openalex.org/I78270026"]},{"raw_affiliation_string":"Centre for DNA Fingerprinting and Diagnostics (CDFD) Hyderabad India","institution_ids":["https://openalex.org/I78270026"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103050407"],"corresponding_institution_ids":["https://openalex.org/I78270026"],"apc_list":{"value":7990,"currency":"USD","value_usd":7990},"apc_paid":null,"fwci":1.8901,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.85210115,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"37","issue":"2","first_page":"183","last_page":"200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/suv39h1","display_name":"SUV39H1","score":1.0},{"id":"https://openalex.org/keywords/histone-methyltransferase","display_name":"histone methyltransferase","score":0.9950000047683716},{"id":"https://openalex.org/keywords/mycobacteria","display_name":"mycobacteria","score":0.7450000047683716},{"id":"https://openalex.org/keywords/histone-like-proteins","display_name":"histone-like proteins","score":0.6610000133514404},{"id":"https://openalex.org/keywords/trimethylation","display_name":"trimethylation","score":0.7829999923706055},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.7870000004768372},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.9700000286102295},{"id":"https://openalex.org/keywords/epigenetic-modulation","display_name":"epigenetic modulation","score":0.800000011920929},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.6539999842643738},{"id":"https://openalex.org/keywords/mycobacterium","display_name":"Mycobacterium","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9189378619194031},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.6259223222732544},{"id":"https://openalex.org/C91965660","wikidata":"https://www.wikidata.org/wiki/Q415875","display_name":"Methyltransferase","level":4,"score":0.5921993851661682},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.47748705744743347},{"id":"https://openalex.org/C150425827","wikidata":"https://www.wikidata.org/wiki/Q2560317","display_name":"Histone methyltransferase","level":4,"score":0.47662436962127686},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43768125772476196},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3724702000617981},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.3291316032409668},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1641649305820465}],"mesh":[{"descriptor_ui":"D000074084","descriptor_name":"THP-1 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008745","descriptor_name":"Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008780","descriptor_name":"Methyltransferases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009163","descriptor_name":"Mycobacterium bovis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D012097","descriptor_name":"Repressor Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014376","descriptor_name":"Tuberculosis","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D017737","descriptor_name":"Macrophages, Peritoneal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D017737","descriptor_name":"Macrophages, Peritoneal","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D017737","descriptor_name":"Macrophages, Peritoneal","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.15252/embj.201796918","doi":"https://doi.org/10.15252/embj.201796918","is_oa":true,"landing_page_url":"https://doi.org/10.15252/embj.201796918","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.201796918","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5307722","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5771397","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5771397","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5771397","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO J","raw_type":"Text"},{"id":"pmid:29170282","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29170282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.15252/embj.201796918","doi":"https://doi.org/10.15252/embj.201796918","is_oa":true,"landing_page_url":"https://doi.org/10.15252/embj.201796918","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/embj.201796918","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1478718175","display_name":null,"funder_award_id":"BT/PR3260/BRB/10/967/2011","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"}],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320320721","display_name":"Council of Scientific and Industrial Research, India","ror":"https://ror.org/021wm7p51"},{"id":"https://openalex.org/F4320320767","display_name":"University Grants Commission","ror":"https://ror.org/04p800546"},{"id":"https://openalex.org/F4320324655","display_name":"University of Hyderabad","ror":"https://ror.org/04a7rxb17"},{"id":"https://openalex.org/F4320336105","display_name":"Centre for DNA Fingerprinting and Diagnostics","ror":"https://ror.org/04psbxy09"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2769737456.pdf","grobid_xml":"https://content.openalex.org/works/W2769737456.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1549366169","https://openalex.org/W1646217211","https://openalex.org/W1829540693","https://openalex.org/W1891793539","https://openalex.org/W1897208764","https://openalex.org/W1922686819","https://openalex.org/W1964249139","https://openalex.org/W1964399190","https://openalex.org/W1967841171","https://openalex.org/W1968384393","https://openalex.org/W1975241669","https://openalex.org/W1981829354","https://openalex.org/W1986296823","https://openalex.org/W1992774222","https://openalex.org/W1994248843","https://openalex.org/W1995700909","https://openalex.org/W1995850701","https://openalex.org/W1999337138","https://openalex.org/W2008301887","https://openalex.org/W2010429928","https://openalex.org/W2025940446","https://openalex.org/W2039399915","https://openalex.org/W2054933678","https://openalex.org/W2060863780","https://openalex.org/W2064297857","https://openalex.org/W2065627587","https://openalex.org/W2067210225","https://openalex.org/W2069433314","https://openalex.org/W2075038734","https://openalex.org/W2101726457","https://openalex.org/W2106642338","https://openalex.org/W2115377549","https://openalex.org/W2119036640","https://openalex.org/W2119298759","https://openalex.org/W2141452262","https://openalex.org/W2143256071","https://openalex.org/W2144440398","https://openalex.org/W2158977162","https://openalex.org/W2159880526","https://openalex.org/W2160675732","https://openalex.org/W2169553739","https://openalex.org/W2173574671","https://openalex.org/W2177694784","https://openalex.org/W2191007893","https://openalex.org/W2264175950","https://openalex.org/W2343309337","https://openalex.org/W2586611497","https://openalex.org/W4250358581","https://openalex.org/W4297157124"],"related_works":["https://openalex.org/W2264175950","https://openalex.org/W4321996516","https://openalex.org/W4390052990","https://openalex.org/W1981829354","https://openalex.org/W2996969764","https://openalex.org/W2178841408","https://openalex.org/W7204023135","https://openalex.org/W4313405723","https://openalex.org/W4292590128","https://openalex.org/W4414258589"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-12-04T00:00:00"}