{"id":"https://openalex.org/W2769017338","doi":"https://doi.org/10.1016/j.conb.2017.11.004","title":"Specification, plasticity and evolutionary origin of peripheral glial cells","display_name":"Specification, plasticity and evolutionary origin of peripheral glial cells","publication_year":2017,"publication_date":"2017-11-21","ids":{"openalex":"https://openalex.org/W2769017338","doi":"https://doi.org/10.1016/j.conb.2017.11.004","mag":"2769017338","pmid":"https://pubmed.ncbi.nlm.nih.gov/29161639"},"language":"en","primary_location":{"id":"doi:10.1016/j.conb.2017.11.004","doi":"https://doi.org/10.1016/j.conb.2017.11.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.conb.2017.11.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0959438817300557/pdf","source":{"id":"https://openalex.org/S120775027","display_name":"Current Opinion in Neurobiology","issn_l":"0959-4388","issn":["0959-4388","1873-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Neurobiology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0959438817300557/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004024009","display_name":"Maria Eleni Kastriti","orcid":"https://orcid.org/0000-0002-0563-7399","observed_orcids":["https://orcid.org/0000-0002-0563-7399"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Maria Eleni Kastriti","raw_affiliation_strings":["Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076800395","display_name":"Igor I. Adameyko","orcid":"https://orcid.org/0000-0001-5471-0356","observed_orcids":["https://orcid.org/0000-0001-5471-0356"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","SE"],"is_corresponding":true,"raw_author_name":"Igor Adameyko","raw_affiliation_strings":["Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden; Center for Brain Research, Medical University Vienna, 1090 Vienna, Austria. Electronic address: igor.adameyko@ki.se","Center for Brain Research, Medical University Vienna, 1090 Vienna, Austria","Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden; Center for Brain Research, Medical University Vienna, 1090 Vienna, Austria. Electronic address: igor.adameyko@ki.se","institution_ids":["https://openalex.org/I28166907","https://openalex.org/I76134821"]},{"raw_affiliation_string":"Center for Brain Research, Medical University Vienna, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5076800395"],"corresponding_institution_ids":["https://openalex.org/I28166907","https://openalex.org/I76134821"],"apc_list":{"value":4320,"currency":"USD","value_usd":4320},"apc_paid":{"value":3498,"currency":"EUR","value_usd":3772},"fwci":1.0824,"has_fulltext":true,"cited_by_count":77,"citation_normalized_percentile":{"value":0.71747212,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"47","issue":null,"first_page":"196","last_page":"202"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.5878999829292297,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.5878999829292297,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.2863999903202057,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12237","display_name":"Congenital gastrointestinal and neural anomalies","score":0.0737999975681305,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peripheral-glia","display_name":"peripheral glia","score":0.875},{"id":"https://openalex.org/keywords/schwann-cells","display_name":"Schwann cells","score":0.984000027179718},{"id":"https://openalex.org/keywords/satellite-glia","display_name":"satellite glia","score":0.6890000104904175},{"id":"https://openalex.org/keywords/enteric-glial-cells","display_name":"enteric glial cells","score":0.9950000047683716},{"id":"https://openalex.org/keywords/neural-crest","display_name":"neural crest","score":0.7829999923706055},{"id":"https://openalex.org/keywords/schwann-cell-precursors","display_name":"Schwann cell precursors","score":0.9800000190734863},{"id":"https://openalex.org/keywords/myelination","display_name":"myelination","score":0.9779999852180481},{"id":"https://openalex.org/keywords/gene-regulatory-networks","display_name":"gene regulatory networks","score":0.8889999985694885},{"id":"https://openalex.org/keywords/glial-plasticity","display_name":"glial plasticity","score":0.6600000262260437}],"concepts":[{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.9188019037246704},{"id":"https://openalex.org/C2777004073","wikidata":"https://www.wikidata.org/wiki/Q465621","display_name":"Schwann cell","level":2,"score":0.7229663133621216},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7169811129570007},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.656183123588562},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.6265178918838501},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.5329412221908569},{"id":"https://openalex.org/C2992459734","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neural cell","level":3,"score":0.4462241530418396},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.4382481873035431},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.4128796458244324},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3963348865509033},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3606337308883667},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.23397529125213623},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21392306685447693},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1186361312866211}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009457","descriptor_name":"Neuroglia","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012583","descriptor_name":"Schwann Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D017933","descriptor_name":"Peripheral Nervous System","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058953","descriptor_name":"Neural Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.conb.2017.11.004","doi":"https://doi.org/10.1016/j.conb.2017.11.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.conb.2017.11.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0959438817300557/pdf","source":{"id":"https://openalex.org/S120775027","display_name":"Current Opinion in Neurobiology","issn_l":"0959-4388","issn":["0959-4388","1873-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Neurobiology","raw_type":"journal-article"},{"id":"pmid:29161639","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29161639","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in neurobiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.conb.2017.11.004","doi":"https://doi.org/10.1016/j.conb.2017.11.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.conb.2017.11.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0959438817300557/pdf","source":{"id":"https://openalex.org/S120775027","display_name":"Current Opinion in Neurobiology","issn_l":"0959-4388","issn":["0959-4388","1873-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Neurobiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2769017338.pdf","grobid_xml":"https://content.openalex.org/works/W2769017338.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W151443056","https://openalex.org/W1528765396","https://openalex.org/W1665419471","https://openalex.org/W1843210218","https://openalex.org/W1949522323","https://openalex.org/W1958675029","https://openalex.org/W1960355435","https://openalex.org/W1968095594","https://openalex.org/W1970981127","https://openalex.org/W1975719696","https://openalex.org/W1975997945","https://openalex.org/W1976731473","https://openalex.org/W1984089779","https://openalex.org/W1986238441","https://openalex.org/W1988866156","https://openalex.org/W1990474842","https://openalex.org/W1998279268","https://openalex.org/W2013204606","https://openalex.org/W2016077756","https://openalex.org/W2017478350","https://openalex.org/W2021524071","https://openalex.org/W2028934778","https://openalex.org/W2045926445","https://openalex.org/W2052315988","https://openalex.org/W2052624565","https://openalex.org/W2066176521","https://openalex.org/W2077683978","https://openalex.org/W2082178034","https://openalex.org/W2086609695","https://openalex.org/W2087065964","https://openalex.org/W2092322285","https://openalex.org/W2102718676","https://openalex.org/W2102880206","https://openalex.org/W2113404473","https://openalex.org/W2120442017","https://openalex.org/W2122423011","https://openalex.org/W2124421908","https://openalex.org/W2129102004","https://openalex.org/W2129605816","https://openalex.org/W2139836251","https://openalex.org/W2146930660","https://openalex.org/W2147372806","https://openalex.org/W2148909614","https://openalex.org/W2151445759","https://openalex.org/W2162484161","https://openalex.org/W2168075066","https://openalex.org/W2279320212","https://openalex.org/W2437591938","https://openalex.org/W2522536498","https://openalex.org/W2590549721","https://openalex.org/W2595623140","https://openalex.org/W2726594986","https://openalex.org/W7096265544"],"related_works":["https://openalex.org/W3047249592","https://openalex.org/W2092322285","https://openalex.org/W2095733702","https://openalex.org/W2030611592","https://openalex.org/W2127393813","https://openalex.org/W2091420016","https://openalex.org/W1676066055","https://openalex.org/W2919240524","https://openalex.org/W4221054803","https://openalex.org/W2790890957"],"abstract_inverted_index":{"Peripheral":[0],"glia":[1,16],"includes":[2],"predominantly":[3],"myelinating":[4],"and":[5,14,49,55,61,66,70,94,108,119],"non-myelinating":[6],"Schwann":[7,37,79,105],"cells":[8],"in":[9,86],"addition":[10],"to":[11,110],"satellite,":[12],"terminal":[13],"enteric":[15,67],"as":[17,19],"well":[18],"other":[20,71],"unresolved":[21],"subtypes":[22],"with":[23],"localized":[24],"functions.":[25],"Of":[26],"these":[27],"subtypes,":[28],"all":[29],"of":[30,77,103],"them":[31],"originate":[32],"from":[33],"neural":[34,46],"crest-derived":[35],"embryonic":[36],"cell":[38,72,80,106],"precursors":[39],"(SCPs).":[40],"Specific":[41],"gene":[42],"regulatory":[43],"networks":[44],"control":[45],"crest":[47],"specification":[48],"downstream":[50],"events,":[51],"including":[52],"SCP":[53],"differentiation":[54],"myelination.":[56],"Embryonic":[57],"SCPs":[58],"are":[59],"multipotent":[60],"generate":[62],"neuroendocrine":[63],"cells,":[64],"parasympathetic":[65],"neurons,":[68],"melanocytes":[69],"types.":[73],"The":[74],"evolutionary":[75,112],"origin":[76],"peripheral":[78,95,120],"lineage":[81,107],"is":[82],"not":[83],"widely":[84],"discussed":[85],"the":[87,100,104],"literature,":[88],"despite":[89],"numerous":[90],"similarities":[91],"between":[92,117],"central":[93,118],"glia.":[96],"Here,":[97],"we":[98],"review":[99],"major":[101],"features":[102],"proceed":[109],"an":[111],"discussion":[113],"around":[114],"possible":[115],"relations":[116],"glial":[121],"cells.":[122]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-12-04T00:00:00"}