{"id":"https://openalex.org/W2768544943","doi":"https://doi.org/10.1111/hiv.12566","title":"Improvement in lipids after switch to boosted atazanavir or darunavir in children/adolescents with perinatally acquired HIV on older protease inhibitors: results from the Pediatric HIV / AIDS Cohort Study","display_name":"Improvement in lipids after switch to boosted atazanavir or darunavir in children/adolescents with perinatally acquired HIV on older protease inhibitors: results from the Pediatric HIV / AIDS Cohort Study","publication_year":2017,"publication_date":"2017-11-21","ids":{"openalex":"https://openalex.org/W2768544943","doi":"https://doi.org/10.1111/hiv.12566","mag":"2768544943","pmid":"https://pubmed.ncbi.nlm.nih.gov/29159965","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5821593"},"language":"en","primary_location":{"id":"doi:10.1111/hiv.12566","doi":"https://doi.org/10.1111/hiv.12566","is_oa":false,"landing_page_url":"https://doi.org/10.1111/hiv.12566","pdf_url":null,"source":{"id":"https://openalex.org/S56736983","display_name":"HIV Medicine","issn_l":"1464-2662","issn":["1464-2662","1468-1293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5821593","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032384460","display_name":"Jennifer K. Jao","orcid":"https://orcid.org/0000-0003-1894-6040","observed_orcids":["https://orcid.org/0000-0003-1894-6040"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"J Jao","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085857257","display_name":"Wendy Yu","orcid":"https://orcid.org/0000-0001-5967-2352","observed_orcids":["https://orcid.org/0000-0001-5967-2352"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W Yu","raw_affiliation_strings":["Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056422504","display_name":"Kunjal Patel","orcid":"https://orcid.org/0000-0003-0002-681X","observed_orcids":["https://orcid.org/0000-0003-0002-681X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K Patel","raw_affiliation_strings":["Department of Epidemiology, Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111494337","display_name":"TL Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"TL Miller","raw_affiliation_strings":["Department of Pediatrics, University of Miami, Miami, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Miami, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057052060","display_name":"Brad Karalius","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B Karalius","raw_affiliation_strings":["Department of Epidemiology, Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055821983","display_name":"Mitchell E. Geffner","orcid":"https://orcid.org/0000-0002-0384-3287","observed_orcids":["https://orcid.org/0000-0002-0384-3287"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I4405270452","display_name":"Saban Research Institute","ror":"https://ror.org/00qe7sv26","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405270452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"ME Geffner","raw_affiliation_strings":["Keck School of Medicine of USC, The Saban Research Institute of Children's Hospital Los Angeles, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Keck School of Medicine of USC, The Saban Research Institute of Children's Hospital Los Angeles, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212","https://openalex.org/I4405270452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045595295","display_name":"Linda Anne DiMeglio","orcid":"https://orcid.org/0000-0002-8033-6078","observed_orcids":["https://orcid.org/0000-0002-8033-6078"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"LA DiMeglio","raw_affiliation_strings":["Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038603092","display_name":"Ayesha Mirza","orcid":"https://orcid.org/0000-0002-2671-0903","observed_orcids":["https://orcid.org/0000-0002-2671-0903"]},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A Mirza","raw_affiliation_strings":["Department of Pediatrics, University of Florida College of Medicine, Jacksonville, FL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Florida College of Medicine, Jacksonville, FL, USA","institution_ids":["https://openalex.org/I33213144","https://openalex.org/I61515104"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031734452","display_name":"JS Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I72816309","display_name":"Drexel University","ror":"https://ror.org/04bdffz58","country_code":"US","type":"education","lineage":["https://openalex.org/I72816309"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JS Chen","raw_affiliation_strings":["Department of Pediatrics, Drexel University College of Medicine, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Drexel University College of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I72816309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109970254","display_name":"Maggie Silio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Silio","raw_affiliation_strings":["Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108648118","display_name":"EJ McFarland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"EJ McFarland","raw_affiliation_strings":["Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA","institution_ids":["https://openalex.org/I51713134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109854170","display_name":"RB Van Dyke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"RB Van Dyke","raw_affiliation_strings":["Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029271602","display_name":"Denise L. Jacobson","orcid":"https://orcid.org/0000-0002-5896-7148","observed_orcids":["https://orcid.org/0000-0002-5896-7148"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D Jacobson","raw_affiliation_strings":["Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":null,"display_name":"the Pediatric HIV/AIDS Cohort Study (PHACS) Adolescent Master Protocol (AMP) study","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"the Pediatric HIV/AIDS Cohort Study (PHACS) Adolescent Master Protocol (AMP) study","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5032384460"],"corresponding_institution_ids":["https://openalex.org/I98704320"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":null,"fwci":0.8481,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.73529838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"19","issue":"3","first_page":"175","last_page":"183"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perinatal-hiv-infection","display_name":"perinatal HIV infection","score":0.9290000200271606},{"id":"https://openalex.org/keywords/pediatric-hiv","display_name":"pediatric HIV","score":0.6010000109672546},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.6200000047683716},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8980000019073486},{"id":"https://openalex.org/keywords/atazanavir-ritonavir","display_name":"atazanavir/ritonavir","score":0.9070000052452087},{"id":"https://openalex.org/keywords/darunavir-ritonavir","display_name":"darunavir/ritonavir","score":1.0},{"id":"https://openalex.org/keywords/protease-inhibitors","display_name":"protease inhibitors","score":0.8539999723434448},{"id":"https://openalex.org/keywords/antiretroviral-therapy-switching","display_name":"antiretroviral therapy switching","score":0.8679999709129333},{"id":"https://openalex.org/keywords/lipid-changes","display_name":"lipid changes","score":0.5929999947547913},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.906000018119812},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.7940000295639038},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.8579999804496765},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9940000176429749},{"id":"https://openalex.org/keywords/total-cholesterol-hdl-ratio","display_name":"TC/HDL-C ratio","score":0.9520000219345093},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6740000247955322},{"id":"https://openalex.org/keywords/lopinavir-ritonavir","display_name":"lopinavir/ritonavir","score":0.9520000219345093},{"id":"https://openalex.org/keywords/nelfinavir","display_name":"nelfinavir","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C2779182219","wikidata":"https://www.wikidata.org/wiki/Q3765251","display_name":"Darunavir","level":5,"score":0.8717429637908936},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.837419867515564},{"id":"https://openalex.org/C2779298103","wikidata":"https://www.wikidata.org/wiki/Q422618","display_name":"Ritonavir","level":5,"score":0.7456560134887695},{"id":"https://openalex.org/C2778414717","wikidata":"https://www.wikidata.org/wiki/Q423467","display_name":"Atazanavir","level":5,"score":0.7205857038497925},{"id":"https://openalex.org/C62746215","wikidata":"https://www.wikidata.org/wiki/Q14890615","display_name":"Apolipoprotein B","level":3,"score":0.5838687419891357},{"id":"https://openalex.org/C2777182164","wikidata":"https://www.wikidata.org/wiki/Q422585","display_name":"Lopinavir","level":5,"score":0.5280790328979492},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.520373523235321},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.4181019067764282},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.4176400303840637},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4048413038253784},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.376213937997818},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.36187973618507385},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.31937092542648315},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.249293714761734},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.15362539887428284}],"mesh":[{"descriptor_ui":"D000069446","descriptor_name":"Atazanavir Sulfate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000069454","descriptor_name":"Darunavir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D017320","descriptor_name":"HIV Protease Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019438","descriptor_name":"Ritonavir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/hiv.12566","doi":"https://doi.org/10.1111/hiv.12566","is_oa":false,"landing_page_url":"https://doi.org/10.1111/hiv.12566","pdf_url":null,"source":{"id":"https://openalex.org/S56736983","display_name":"HIV Medicine","issn_l":"1464-2662","issn":["1464-2662","1468-1293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV Medicine","raw_type":"journal-article"},{"id":"pmid:29159965","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29159965","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV medicine","raw_type":"Comparative Study"},{"id":"pmh:oai:europepmc.org:5370266","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5821593","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5821593","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5821593","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"HIV Med","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5370266","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5821593","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1121950248","display_name":null,"funder_award_id":"HD052104","funder_id":"https://openalex.org/F4320310142","funder_display_name":"Tulane University"},{"id":"https://openalex.org/G4052168949","display_name":"Metabolic Effects of In Utero Antiretrovirals on HIV Exposed Uninfected Infants","funder_award_id":"K23HD070760","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G4625201692","display_name":"Pediatric HIV/AIDS Cohort Study (PHACS) Coordinating Center (CC) (U01)","funder_award_id":"U01HD052104","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7161945251","display_name":"Pediatric HIV/AIDS Cohort Study (PHACS): Data and Operations Center (DOC).","funder_award_id":"U01HD052102","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G9000894295","display_name":"The University of North Carolina Center for AIDS Research","funder_award_id":"P30AI050410","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"},{"id":"https://openalex.org/F4320310142","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21"},{"id":"https://openalex.org/F4320317807","display_name":"International Maternal Pediatric Adolescent AIDS Clinical Trials Network","ror":null},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"},{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337364","display_name":"National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"},{"id":"https://openalex.org/F4320337464","display_name":"Office of AIDS Research","ror":"https://ror.org/02e3wq066"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W289059651","https://openalex.org/W343506127","https://openalex.org/W1709407542","https://openalex.org/W1963763254","https://openalex.org/W1967345282","https://openalex.org/W1971771720","https://openalex.org/W1972080883","https://openalex.org/W1976022560","https://openalex.org/W1978444406","https://openalex.org/W1994477876","https://openalex.org/W2001969007","https://openalex.org/W2002008843","https://openalex.org/W2015491389","https://openalex.org/W2025423755","https://openalex.org/W2032588857","https://openalex.org/W2035044461","https://openalex.org/W2043706984","https://openalex.org/W2049969210","https://openalex.org/W2061496424","https://openalex.org/W2064524230","https://openalex.org/W2073013889","https://openalex.org/W2084627985","https://openalex.org/W2092497043","https://openalex.org/W2110717475","https://openalex.org/W2119340816","https://openalex.org/W2120110886","https://openalex.org/W2133801311","https://openalex.org/W2137569461","https://openalex.org/W2143357783","https://openalex.org/W2144518502","https://openalex.org/W2145860140","https://openalex.org/W2152197563","https://openalex.org/W2153879448","https://openalex.org/W2159816288","https://openalex.org/W2162291827","https://openalex.org/W2166117607","https://openalex.org/W2166168319","https://openalex.org/W2168536722","https://openalex.org/W2168680123","https://openalex.org/W2171236519","https://openalex.org/W2262354148","https://openalex.org/W2288605373","https://openalex.org/W2325164377","https://openalex.org/W2333957308","https://openalex.org/W2487039045","https://openalex.org/W2885228104","https://openalex.org/W2955509706","https://openalex.org/W3001764054"],"related_works":["https://openalex.org/W1991551730","https://openalex.org/W2040028729","https://openalex.org/W2584657670","https://openalex.org/W2025423755","https://openalex.org/W1988101744","https://openalex.org/W2948605198","https://openalex.org/W2885518912","https://openalex.org/W2187888308","https://openalex.org/W2580990122","https://openalex.org/W1972055759"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Dyslipidaemia":[1],"is":[2],"common":[3],"in":[4,20,33,52,56,114,181,209,240,244,250],"perinatally":[5],"HIV-infected":[6],"(PHIV)":[7],"youth":[8,22,54],"receiving":[9],"protease":[10],"inhibitors":[11],"(PIs).":[12],"Few":[13],"studies":[14],"have":[15],"evaluated":[16],"longitudinal":[17,31],"lipid":[18],"changes":[19,32],"PHIV":[21,53,126,251],"after":[23],"switch":[24,103,166,211,214,233],"to":[25,70,97,104,123,129,151,167,215,234],"newer":[26],"PIs.":[27],"METHODS:":[28],"We":[29],"compared":[30],"fasting":[34],"lipids":[35],"[total":[36],"cholesterol":[37,43,47],"(TC),":[38],"triglycerides":[39],"(TG),":[40],"low-density":[41],"lipoprotein":[42,46],"(LDL-C),":[44],"high-density":[45],"(HDL-C),":[48],"and":[49,84,143,161,246],"TC:HDL-C":[50,248],"ratio]":[51],"enrolled":[55],"the":[57,99,110,182,210,223,247],"Pediatric":[58],"HIV/AIDS":[59],"Cohort":[60],"Study":[61],"(PHACS)":[62],"Adolescent":[63],"Master":[64],"Protocol":[65],"(AMP)":[66],"study":[67],"who":[68],"switched":[69,128],"atazanavir/ritonavir":[71],"(ATV/r)-":[72],"or":[73,106,131,169,217,228,236],"darunavir/ritonavir":[74],"(DRV/r)-based":[75],"antiretroviral":[76],"therapy":[77],"(ART)":[78],"from":[79,149],"an":[80,88,137,195],"older":[81,89,138,196],"PI-based":[82],"ART":[83,108],"those":[85],"remaining":[86,193],"on":[87,136,194],"PI.":[90,197],"Generalized":[91],"estimating":[92],"equation":[93],"models":[94],"were":[95],"fitted":[96],"assess":[98],"association":[100],"of":[101,112,179,184,225],"a":[102,165,174],"ATV/r-":[105],"DRV/r-based":[107],"with":[109,173,222],"rate":[111,178,224],"change":[113],"lipids,":[115],"adjusted":[116],"for":[117,156],"potential":[118],"confounders.":[119],"RESULTS:":[120],"From":[121],"2007":[122],"2014,":[124],"47":[125],"children/adolescents":[127],"ATV/r":[130,168,216,235],"DRV/r,":[132],"while":[133],"120":[134],"remained":[135],"PI":[139],"[primarily":[140],"lopinavir/r":[141],"(72%)":[142],"nelfinavir":[144],"(24%)].":[145],"Baseline":[146],"age":[147],"ranged":[148],"7":[150],"21":[152],"years.":[153],"After":[154],"adjustment":[155],"age,":[157],"Tanner":[158],"stage,":[159],"race/ethnicity,":[160],"HIV":[162],"RNA":[163],"level,":[164],"DRV/r":[170,218,237],"was":[171,219],"associated":[172,221],"more":[175,208,241],"rapid":[176,242],"annual":[177],"decline":[180],"ratio":[183,249],"TC:HDL-C.":[185],"(\u03b2":[186],"=":[187,190,206],"-0.12;":[188],"P":[189],"0.039)":[191],"than":[192],"On":[198],"average,":[199],"TC":[200,245],"declined":[201],"by":[202],"4.57":[203],"mg/dL/year":[204],"(P":[205],"0.057)":[207],"group.":[212],"A":[213,232],"not":[220],"HDL-C,":[226],"LDL-C,":[227],"TG":[229],"change.":[230],"CONCLUSIONS:":[231],"may":[238],"result":[239],"reduction":[243],"youth,":[252],"potentially":[253],"impacting":[254],"long-term":[255],"cardiovascular":[256],"disease":[257],"risk.":[258]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2017-12-04T00:00:00"}