{"id":"https://openalex.org/W2768020680","doi":"https://doi.org/10.1136/bjophthalmol-2017-310718","title":"Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis","display_name":"Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis","publication_year":2017,"publication_date":"2017-11-09","ids":{"openalex":"https://openalex.org/W2768020680","doi":"https://doi.org/10.1136/bjophthalmol-2017-310718","mag":"2768020680","pmid":"https://pubmed.ncbi.nlm.nih.gov/29122818"},"language":"en","primary_location":{"id":"doi:10.1136/bjophthalmol-2017-310718","doi":"https://doi.org/10.1136/bjophthalmol-2017-310718","is_oa":false,"landing_page_url":"https://doi.org/10.1136/bjophthalmol-2017-310718","pdf_url":null,"source":{"id":"https://openalex.org/S79587146","display_name":"British Journal of Ophthalmology","issn_l":"0007-1161","issn":["0007-1161","1468-2079"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024121483","display_name":"Eric D. Gaier","orcid":"https://orcid.org/0000-0002-2923-0024","observed_orcids":["https://orcid.org/0000-0002-2923-0024"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric D Gaier","raw_affiliation_strings":["Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054993510","display_name":"Aubrey L. Gilbert","orcid":"https://orcid.org/0000-0002-6920-8155","observed_orcids":["https://orcid.org/0000-0002-6920-8155"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aubrey L Gilbert","raw_affiliation_strings":["Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052260050","display_name":"Dean M. Cestari","orcid":"https://orcid.org/0000-0001-6470-489X","observed_orcids":["https://orcid.org/0000-0001-6470-489X"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dean M Cestari","raw_affiliation_strings":["Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050971382","display_name":"John B. Miller","orcid":"https://orcid.org/0000-0003-0109-9738","observed_orcids":["https://orcid.org/0000-0003-0109-9738"]},"institutions":[{"id":"https://openalex.org/I1287163989","display_name":"Massachusetts Eye and Ear Infirmary","ror":"https://ror.org/04g3dn724","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1287163989"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"John B Miller","raw_affiliation_strings":["Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA","Retina Service, Mass. Eye and Ear Infirmary, Harvard Medical School, Boston, MA, 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Retina Service, Mass. Eye and Ear Infirmary, Harvard Medical School, Boston, MA, 02114","institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050971382"],"corresponding_institution_ids":["https://openalex.org/I1287163989","https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":2.4857,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.89857163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"102","issue":"8","first_page":"1141","last_page":"1146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.6855000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.09309999644756317,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.06629999727010727,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/giant-cell-arteritis","display_name":"giant cell arteritis","score":0.9279999732971191},{"id":"https://openalex.org/keywords/optical-coherence-tomography-angiography","display_name":"optical coherence tomography angiography","score":0.9670000076293945},{"id":"https://openalex.org/keywords/visual-field-defects","display_name":"visual field defects","score":0.8109999895095825},{"id":"https://openalex.org/keywords/optic-disc-edema","display_name":"optic disc edema","score":0.949999988079071},{"id":"https://openalex.org/keywords/cotton-wool-spots","display_name":"cotton wool spots","score":0.875},{"id":"https://openalex.org/keywords/choroidal-circulation","display_name":"choroidal blood flow","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9182251691818237},{"id":"https://openalex.org/C2776712624","wikidata":"https://www.wikidata.org/wiki/Q707816","display_name":"Giant cell arteritis","level":4,"score":0.6225792169570923},{"id":"https://openalex.org/C2776474195","wikidata":"https://www.wikidata.org/wiki/Q1144413","display_name":"Fundus photography","level":4,"score":0.5844016075134277},{"id":"https://openalex.org/C2776058522","wikidata":"https://www.wikidata.org/wiki/Q2364768","display_name":"Visual field","level":2,"score":0.5684462189674377},{"id":"https://openalex.org/C2780248432","wikidata":"https://www.wikidata.org/wiki/Q1434206","display_name":"Fluorescein angiography","level":3,"score":0.5551335215568542},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5116794109344482},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.4707639217376709},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.4449097812175751},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.43780121207237244},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3054613769054413},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2540845274925232},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.24890431761741638},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004108","descriptor_name":"Dilatation, Pathologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005451","descriptor_name":"Fluorescein Angiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009412","descriptor_name":"Nerve Fibers","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009898","descriptor_name":"Optic Disk","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":true},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013700","descriptor_name":"Giant Cell Arteritis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013700","descriptor_name":"Giant Cell Arteritis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014786","descriptor_name":"Vision Disorders","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014786","descriptor_name":"Vision Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014794","descriptor_name":"Visual Fields","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018917","descriptor_name":"Optic Neuropathy, Ischemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D018917","descriptor_name":"Optic Neuropathy, Ischemic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019842","descriptor_name":"Ciliary Arteries","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055806","descriptor_name":"Microvessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D058609","descriptor_name":"Visual Field Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1136/bjophthalmol-2017-310718","doi":"https://doi.org/10.1136/bjophthalmol-2017-310718","is_oa":false,"landing_page_url":"https://doi.org/10.1136/bjophthalmol-2017-310718","pdf_url":null,"source":{"id":"https://openalex.org/S79587146","display_name":"British Journal of Ophthalmology","issn_l":"0007-1161","issn":["0007-1161","1468-2079"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Ophthalmology","raw_type":"journal-article"},{"id":"pmid:29122818","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29122818","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The British journal of ophthalmology","raw_type":"Case Reports"},{"id":"pmh:oai:open-archive.highwire.org:bjophthalmol:102/8/1141","doi":null,"is_oa":false,"landing_page_url":"http://bjo.bmj.com/cgi/content/short/102/8/1141","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1580861603","https://openalex.org/W2004395839","https://openalex.org/W2054141521","https://openalex.org/W2067438085","https://openalex.org/W2082723672","https://openalex.org/W2092640259","https://openalex.org/W2117995882","https://openalex.org/W2160436805","https://openalex.org/W2170856389","https://openalex.org/W2336653399","https://openalex.org/W2337373109","https://openalex.org/W2508645847","https://openalex.org/W2516440824","https://openalex.org/W2526484876","https://openalex.org/W2529222518","https://openalex.org/W2537415511","https://openalex.org/W2569075961","https://openalex.org/W2576655622"],"related_works":["https://openalex.org/W4401499654","https://openalex.org/W4406788874","https://openalex.org/W2752686464","https://openalex.org/W4289932563","https://openalex.org/W4295949408","https://openalex.org/W4416202022","https://openalex.org/W2884669393","https://openalex.org/W2519059077","https://openalex.org/W4221020795","https://openalex.org/W4313579648"],"abstract_inverted_index":{"AIMS:":[0],"We":[1,52],"set":[2],"out":[3],"to":[4,41,69,93,131,171],"determine":[5],"the":[6,21,54,94,120,151,203,214,241],"optical":[7],"coherence":[8],"tomographic":[9],"angiography":[10,61],"(OCT-A)":[11],"characteristics":[12],"of":[13,23,35,77,82,90,123,227,243,246],"arteritic":[14],"anterior":[15],"ischaemic":[16,248],"optic":[17,136,249],"neuropathy":[18],"(AAION)":[19],"in":[20,74,96,110,119,158,165,190,207,224,240],"context":[22],"giant":[24],"cell":[25],"arteritis":[26],"(GCA).":[27],"METHODS:":[28],"This":[29],"is":[30],"an":[31],"observational":[32],"case":[33],"series":[34,98,226],"four":[36],"patients":[37,68,89,95,167,228],"with":[38,44,49,112,178,199,229],"AAION":[39,46,78,191,210],"secondary":[40],"GCA,":[42],"three":[43],"unilateral":[45],"and":[47,63,139,168,186,209,220],"one":[48],"bilateral":[50],"AAION.":[51,114],"reviewed":[53],"charts,":[55],"fundus":[56],"photography,":[57],"visual":[58,132,179,200],"fields,":[59],"fluorescein":[60],"(FA)":[62],"OCT-A":[64,145,162,196,232],"images":[65],"for":[66,101],"all":[67],"identify":[70],"a":[71,75,234],"unifying":[72],"theme":[73],"range":[76],"clinical":[79],"severity.":[80],"Imaging":[81],"two":[83,88,124,159,166],"healthy":[84],"control":[85],"eyes":[86,111,122,223],"from":[87],"similar":[91],"age":[92],"our":[97],"were":[99],"used":[100],"comparison.":[102],"RESULTS:":[103],"Superficial":[104],"peripapillary":[105,173],"capillary":[106,127,174],"dilation":[107],"was":[108,116,163],"seen":[109,155,206],"acute":[113,185],"It":[115],"also":[117],"noted":[118],"fellow":[121],"patients.":[125,160],"Retinal":[126],"perfusion":[128,153],"defects":[129,154],"corresponded":[130,177],"field":[133,180],"loss.":[134,181],"Dense":[135],"disc":[137],"oedema":[138],"cotton-wool":[140],"spots":[141],"imparted":[142],"blockage":[143],"effects.":[144],"laminar":[146],"analysis":[147],"did":[148],"not":[149,212],"highlight":[150],"choroidal/choriocapillaris":[152],"on":[156],"FA":[157],"Follow-up":[161],"obtained":[164],"revealed":[169],"progression":[170],"superficial":[172],"attenuation":[175],"that":[176,192,197],"CONCLUSIONS:":[182],"There":[183],"are":[184,193,211],"chronic":[187],"vascular":[188],"changes":[189,205],"detectable":[194],"by":[195],"correspond":[198],"function.":[201],"Though":[202],"microvascular":[204],"GCA":[208,230],"specific,":[213],"nearly":[215],"ubiquitous":[216],"findings":[217],"among":[218],"preclinical":[219],"clinically":[221],"affected":[222],"this":[225],"support":[231],"as":[233],"potentially":[235],"useful":[236],"adjunctive":[237],"diagnostic":[238],"test":[239],"work-up":[242],"ambiguous":[244],"cases":[245],"suspected":[247],"neuropathy.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-11-17T00:00:00"}