{"id":"https://openalex.org/W2767559831","doi":"https://doi.org/10.1002/cpt.934","title":"Comparison of Two Highly Automated ECG Algorithms for Detection of Drug\u2010Induced Cardiac Ion Channel Block","display_name":"Comparison of Two Highly Automated ECG Algorithms for Detection of Drug\u2010Induced Cardiac Ion Channel Block","publication_year":2017,"publication_date":"2017-11-11","ids":{"openalex":"https://openalex.org/W2767559831","doi":"https://doi.org/10.1002/cpt.934","mag":"2767559831","pmid":"https://pubmed.ncbi.nlm.nih.gov/29127703","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5948117"},"language":"en","primary_location":{"id":"doi:10.1002/cpt.934","doi":"https://doi.org/10.1002/cpt.934","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cpt.934","pdf_url":"https://ascpt.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.934","source":{"id":"https://openalex.org/S159852663","display_name":"Clinical Pharmacology & Therapeutics","issn_l":"0009-9236","issn":["0009-9236","1085-8733","1532-6535"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Pharmacology & Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ascpt.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.934","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051610249","display_name":"Marina V. Brockway","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134360","display_name":"VivaQuant (United States)","ror":"https://ror.org/045c7x933","country_code":"US","type":"company","lineage":["https://openalex.org/I4210134360"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Marina Brockway","raw_affiliation_strings":["VivaQuant LLC, St Paul, Minnesota, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VivaQuant LLC, St Paul, Minnesota, USA","institution_ids":["https://openalex.org/I4210134360"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068616711","display_name":"Anthony A. Fossa","orcid":"https://orcid.org/0000-0001-6270-7034","observed_orcids":["https://orcid.org/0000-0001-6270-7034"]},"institutions":[{"id":"https://openalex.org/I2799870999","display_name":"Connecticut Science Center","ror":"https://ror.org/01qpqce32","country_code":"US","type":"archive","lineage":["https://openalex.org/I2799870999"]},{"id":"https://openalex.org/I4210136440","display_name":"ThermoGenesis (United States)","ror":"https://ror.org/03rycrh12","country_code":"US","type":"company","lineage":["https://openalex.org/I4210136440"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony A. Fossa","raw_affiliation_strings":["Fossa Consulting LLC, Mystic, Connecticut, USA"],"raw_orcid":"https://orcid.org/0000-0001-6270-7034","affiliations":[{"raw_affiliation_string":"Fossa Consulting LLC, Mystic, Connecticut, USA","institution_ids":["https://openalex.org/I2799870999","https://openalex.org/I4210136440"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038222647","display_name":"Jay W. Mason","orcid":"https://orcid.org/0000-0002-5713-9906","observed_orcids":["https://orcid.org/0000-0002-5713-9906"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210103137","display_name":"Spaulding Clinical Research (United States)","ror":"https://ror.org/01bg37c61","country_code":"US","type":"company","lineage":["https://openalex.org/I4210103137"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay W. Mason","raw_affiliation_strings":["Division of Cardiology, University of Utah, Salt Lake City, Utah, USA","Spaulding Clinical Research, West Bend, Wisconsin, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, University of Utah, Salt Lake City, Utah, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Spaulding Clinical Research, West Bend, Wisconsin, USA","institution_ids":["https://openalex.org/I4210103137"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5051610249"],"corresponding_institution_ids":["https://openalex.org/I4210134360"],"apc_list":{"value":4410,"currency":"USD","value_usd":4410},"apc_paid":{"value":4410,"currency":"USD","value_usd":4410},"fwci":1.2654,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.82276919,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"104","issue":"2","first_page":"356","last_page":"363"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/automatic-ecg-analysis","display_name":"automated ECG analysis","score":0.5680000185966492},{"id":"https://openalex.org/keywords/arrhythmia-risk","display_name":"arrhythmia risk","score":0.8130000233650208},{"id":"https://openalex.org/keywords/exposure-response-relationship","display_name":"exposure-response relationship","score":0.6610000133514404},{"id":"https://openalex.org/keywords/algorithm-comparison","display_name":"algorithm comparison","score":0.6159999966621399},{"id":"https://openalex.org/keywords/linear-mixed-models","display_name":"linear mixed models","score":0.5490000247955322},{"id":"https://openalex.org/keywords/akaike-information-criterion","display_name":"Akaike information criterion","score":0.8289999961853027},{"id":"https://openalex.org/keywords/dofetilide","display_name":"dofetilide","score":0.628000020980835},{"id":"https://openalex.org/keywords/verapamil","display_name":"verapamil","score":0.9330000281333923},{"id":"https://openalex.org/keywords/quinidine","display_name":"quinidine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ranolazine","display_name":"ranolazine","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5980799794197083},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5757918357849121},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5645235776901245},{"id":"https://openalex.org/C2777796741","wikidata":"https://www.wikidata.org/wiki/Q3712521","display_name":"Dofetilide","level":3,"score":0.5360482335090637},{"id":"https://openalex.org/C2779177932","wikidata":"https://www.wikidata.org/wiki/Q907104","display_name":"Ranolazine","level":2,"score":0.5223599672317505},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.4593442380428314},{"id":"https://openalex.org/C3018890749","wikidata":"https://www.wikidata.org/wiki/Q204711","display_name":"Food and drug administration","level":2,"score":0.4407026767730713},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.37055233120918274},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3558708429336548},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3507123291492462},{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.2500265836715698},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.23359504342079163},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000073458","descriptor_name":"Data Warehousing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000889","descriptor_name":"Anti-Arrhythmia Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000889","descriptor_name":"Anti-Arrhythmia Agents","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001331","descriptor_name":"Automation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006329","descriptor_name":"Heart Conduction System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015588","descriptor_name":"Observer Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015716","descriptor_name":"Electrocardiography, Ambulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026902","descriptor_name":"Potassium Channel Blockers","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D061567","descriptor_name":"Voltage-Gated Sodium Channel Blockers","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/cpt.934","doi":"https://doi.org/10.1002/cpt.934","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cpt.934","pdf_url":"https://ascpt.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.934","source":{"id":"https://openalex.org/S159852663","display_name":"Clinical Pharmacology & Therapeutics","issn_l":"0009-9236","issn":["0009-9236","1085-8733","1532-6535"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Pharmacology & Therapeutics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5051695","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5948117","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5948117","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5948117","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Pharmacol Ther","raw_type":"Text"},{"id":"pmid:29127703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29127703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical pharmacology and therapeutics","raw_type":"Comparative Study"}],"best_oa_location":{"id":"doi:10.1002/cpt.934","doi":"https://doi.org/10.1002/cpt.934","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cpt.934","pdf_url":"https://ascpt.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cpt.934","source":{"id":"https://openalex.org/S159852663","display_name":"Clinical Pharmacology & Therapeutics","issn_l":"0009-9236","issn":["0009-9236","1085-8733","1532-6535"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Pharmacology & Therapeutics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3185875891","display_name":"Sensing lead for denoising ambulatory ECGs and false positive event reduction","funder_award_id":"1r43hl110739-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5471462883","display_name":"Sensing lead for denoising ambulatory ECGs and false positive event reduction","funder_award_id":"R44DA041815","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G6755584747","display_name":null,"funder_award_id":"R43 HL110739","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2767559831.pdf","grobid_xml":"https://content.openalex.org/works/W2767559831.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W43308025","https://openalex.org/W1136523086","https://openalex.org/W1907607489","https://openalex.org/W1970333224","https://openalex.org/W1991902077","https://openalex.org/W1993315880","https://openalex.org/W2060133408","https://openalex.org/W2113927644","https://openalex.org/W2143930899","https://openalex.org/W2148346557","https://openalex.org/W2162800060","https://openalex.org/W2170377367","https://openalex.org/W2253814216","https://openalex.org/W2328454508","https://openalex.org/W2568710328","https://openalex.org/W2570352644","https://openalex.org/W2613017973","https://openalex.org/W2794007849","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2170377367","https://openalex.org/W2802726191","https://openalex.org/W3210551668","https://openalex.org/W2899853674","https://openalex.org/W2769665901","https://openalex.org/W2735953620","https://openalex.org/W2770244781","https://openalex.org/W2793848618","https://openalex.org/W2751193250","https://openalex.org/W2147629838"],"abstract_inverted_index":{")":[0],"repolarization":[1],"duration":[2],"can":[3],"differentiate":[4],"selective":[5],"potassium":[6],"block":[7,15],"with":[8,16,74,98,128],"a":[9],"high":[10],"arrhythmia":[11],"risk":[12,18],"from":[13],"multichannel":[14],"lower":[17,130],"in":[19,65,69,101,113,118],"subjects":[20],"receiving":[21],"dofetilide,":[22],"verapamil,":[23],"quinidine,":[24],"or":[25],"ranolazine.":[26],"The":[27,109],"purpose":[28],"of":[29,107,123],"this":[30],"study":[31],"was":[32],"to":[33,59],"determine":[34,60],"if":[35,61],"the":[36,39,55,88,94,102,119,124],"findings":[37],"by":[38,87],"FDA":[40,95],"using":[41,49],"their":[42],"published":[43],"software":[44,52,111],"algorithm":[45,53],"could":[46],"be":[47],"corroborated":[48],"an":[50,114],"alternative":[51,110],"for":[54],"same":[56],"metrics":[57],"and":[58,79,105],"methodological":[62],"differences":[63,68,100],"resulted":[64,112],"clinically":[66],"meaningful":[67],"interpretation.":[70],"Exposure-response":[71],"relationships":[72],"computed":[73],"linear":[75],"mixed":[76,125],"effects":[77,82,126],"models":[78,127],"mean":[80],"maximal":[81],"on":[83],"ECG":[84],"intervals":[85,122],"measured":[86],"two":[89],"algorithms":[90],"were":[91],"similar,":[92],"corroborating":[93],"findings,":[96],"but":[97],"some":[99],"modeled":[103],"slopes":[104],"magnitude":[106],"changes.":[108],"average":[115],"25%":[116],"reduction":[117],"95%":[120],"confidence":[121],"generally":[129],"Akaike":[131],"Information":[132],"Criterion":[133],"values.":[134]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-11-17T00:00:00"}