{"id":"https://openalex.org/W2763849935","doi":"https://doi.org/10.3233/jad-170478","title":"Job Loss After Diagnosis of Early-Onset Dementia: A Matched Cohort Study","display_name":"Job Loss After Diagnosis of Early-Onset Dementia: A Matched Cohort Study","publication_year":2017,"publication_date":"2017-10-10","ids":{"openalex":"https://openalex.org/W2763849935","doi":"https://doi.org/10.3233/jad-170478","mag":"2763849935","pmid":"https://pubmed.ncbi.nlm.nih.gov/29036820","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5676857"},"language":"en","primary_location":{"id":"doi:10.3233/jad-170478","doi":"https://doi.org/10.3233/jad-170478","is_oa":true,"landing_page_url":"https://doi.org/10.3233/jad-170478","pdf_url":"https://content.iospress.com:443/download/journal-of-alzheimers-disease/jad170478?id=journal-of-alzheimers-disease%2Fjad170478","source":{"id":"https://openalex.org/S25155249","display_name":"Journal of Alzheimer s Disease","issn_l":"1387-2877","issn":["1387-2877","1875-8908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer's Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://content.iospress.com:443/download/journal-of-alzheimers-disease/jad170478?id=journal-of-alzheimers-disease%2Fjad170478","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010296584","display_name":"Nobuo Sakata","orcid":"https://orcid.org/0000-0003-0599-3235","observed_orcids":["https://orcid.org/0000-0003-0599-3235"]},"institutions":[{"id":"https://openalex.org/I4210132767","display_name":"Institute for Health Economics and Policy","ror":"https://ror.org/03e5y0y34","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4210132767"]},{"id":"https://openalex.org/I4405252882","display_name":"Association for Health Economics Research and Social Insurance and Welfare","ror":"https://ror.org/002wgkd29","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4405252882"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuo Sakata","raw_affiliation_strings":["Research Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan","institution_ids":["https://openalex.org/I4210132767","https://openalex.org/I4405252882"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050569773","display_name":"Yasuyuki Okumura","orcid":"https://orcid.org/0000-0001-5851-8919","observed_orcids":["https://orcid.org/0000-0001-5851-8919"]},"institutions":[{"id":"https://openalex.org/I4210132767","display_name":"Institute for Health Economics and Policy","ror":"https://ror.org/03e5y0y34","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4210132767"]},{"id":"https://openalex.org/I4405252882","display_name":"Association for Health Economics Research and Social Insurance and Welfare","ror":"https://ror.org/002wgkd29","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4405252882"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yasuyuki Okumura","raw_affiliation_strings":["Research Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan","institution_ids":["https://openalex.org/I4210132767","https://openalex.org/I4405252882"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050569773"],"corresponding_institution_ids":["https://openalex.org/I4210132767","https://openalex.org/I4405252882"],"apc_list":null,"apc_paid":null,"fwci":2.682,"has_fulltext":true,"cited_by_count":57,"citation_normalized_percentile":{"value":0.89394428,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"60","issue":"4","first_page":"1231","last_page":"1235"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11631","display_name":"Retirement, Disability, and Employment","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/3317","display_name":"Demography"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11514","display_name":"Disability Education and Employment","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/3304","display_name":"Education"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-onset-dementia","display_name":"early-onset dementia","score":1.0},{"id":"https://openalex.org/keywords/job-loss","display_name":"job loss","score":0.9869999885559082}],"concepts":[{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.777289628982544},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.7568559646606445},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6343741416931152},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.6152966618537903},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.5934075117111206},{"id":"https://openalex.org/C2992694208","wikidata":"https://www.wikidata.org/wiki/Q8436","display_name":"Family member","level":2,"score":0.47419410943984985},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.3601382374763489},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3252676725387573},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23845058679580688},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.12516507506370544},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D003704","descriptor_name":"Dementia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D004651","descriptor_name":"Employment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3233/jad-170478","doi":"https://doi.org/10.3233/jad-170478","is_oa":true,"landing_page_url":"https://doi.org/10.3233/jad-170478","pdf_url":"https://content.iospress.com:443/download/journal-of-alzheimers-disease/jad170478?id=journal-of-alzheimers-disease%2Fjad170478","source":{"id":"https://openalex.org/S25155249","display_name":"Journal of Alzheimer s Disease","issn_l":"1387-2877","issn":["1387-2877","1875-8908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer's Disease","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4601113","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5676857","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:29036820","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29036820","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer's disease : JAD","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5676857","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5676857/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Alzheimers Dis","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3233/jad-170478","doi":"https://doi.org/10.3233/jad-170478","is_oa":true,"landing_page_url":"https://doi.org/10.3233/jad-170478","pdf_url":"https://content.iospress.com:443/download/journal-of-alzheimers-disease/jad170478?id=journal-of-alzheimers-disease%2Fjad170478","source":{"id":"https://openalex.org/S25155249","display_name":"Journal of Alzheimer s Disease","issn_l":"1387-2877","issn":["1387-2877","1875-8908"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318577","host_organization_name":"IOS Press","host_organization_lineage":["https://openalex.org/P4310318577"],"host_organization_lineage_names":["IOS Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Alzheimer's Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.9211000204086304,"id":"https://metadata.un.org/sdg/8","display_name":"Decent work and economic growth"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1456620602","display_name":null,"funder_award_id":"16dk0207024h0001","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"}],"funders":[{"id":"https://openalex.org/F4320311405","display_name":"Japan Agency for Medical Research and Development","ror":"https://ror.org/004rtk039"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2763849935.pdf","grobid_xml":"https://content.openalex.org/works/W2763849935.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1964541645","https://openalex.org/W1985905268","https://openalex.org/W1991417008","https://openalex.org/W1997725620","https://openalex.org/W2004093248","https://openalex.org/W2007389916","https://openalex.org/W2008498400","https://openalex.org/W2023220891","https://openalex.org/W2042203462","https://openalex.org/W2049289548","https://openalex.org/W2086197387","https://openalex.org/W2111231379","https://openalex.org/W2161359113","https://openalex.org/W2165579423","https://openalex.org/W2220114986","https://openalex.org/W2338326009","https://openalex.org/W2515757938","https://openalex.org/W2516954351","https://openalex.org/W2548568152","https://openalex.org/W2555419789","https://openalex.org/W2619097621","https://openalex.org/W4244009405"],"related_works":["https://openalex.org/W4416786082","https://openalex.org/W7081981089","https://openalex.org/W4407908088","https://openalex.org/W2611146606","https://openalex.org/W3199617383","https://openalex.org/W4407908265","https://openalex.org/W2972375392","https://openalex.org/W2966094782","https://openalex.org/W2515757938","https://openalex.org/W4413051680"],"abstract_inverted_index":{"Early-onset":[0],"dementia":[1],"(EOD)":[2],"affects":[3],"the":[4,67],"employment":[5,93],"of":[6,37],"patients":[7,70,96],"and":[8,40,59],"family":[9,29,42],"members.":[10],"To":[11],"demonstrate":[12],"how":[13],"likely":[14,75],"employees":[15,39],"are":[16],"to":[17,55,76,95],"leave":[18,77],"their":[19,78],"jobs":[20,79],"after":[21,98],"an":[22],"EOD":[23,46,72],"diagnosis":[24],"for":[25,62],"themselves":[26],"or":[27],"a":[28,33,48],"member,":[30],"we":[31],"conducted":[32],"matched":[34,52],"cohort":[35],"study":[36],"143":[38],"77":[41],"members":[43],"diagnosed":[44],"with":[45,71],"using":[47],"claims":[49],"database.":[50],"We":[51],"these":[53],"participants":[54],"5":[56],"controls":[57,82],"each,":[58],"followed":[60],"them":[61],"approximately":[63],"600":[64],"days.":[65],"In":[66],"employee":[68],"cohort,":[69],"were":[73,81],"more":[74],"than":[80],"(hazard":[83],"ratio:":[84],"2.26).":[85],"This":[86],"suggests":[87],"that":[88],"healthcare":[89],"providers":[90],"should":[91],"offer":[92],"support":[94],"just":[97],"diagnosis.":[99]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2017-10-20T00:00:00"}