{"id":"https://openalex.org/W2762932397","doi":"https://doi.org/10.1093/annonc/mdx376.045","title":"Development of OAT-1746, a novel arginase 1 and 2 inhibitor for cancer immunotherapy","display_name":"Development of OAT-1746, a novel arginase 1 and 2 inhibitor for cancer immunotherapy","publication_year":2017,"publication_date":"2017-09-01","ids":{"openalex":"https://openalex.org/W2762932397","doi":"https://doi.org/10.1093/annonc/mdx376.045","mag":"2762932397"},"language":"en","primary_location":{"id":"doi:10.1093/annonc/mdx376.045","doi":"https://doi.org/10.1093/annonc/mdx376.045","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdx376.045","pdf_url":null,"source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1093/annonc/mdx376.045","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030930495","display_name":"Paulina Seweryna Sta\u0144czak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"P.S. Stanczak","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017316574","display_name":"Marcin Miko\u0142aj Grzybowski","orcid":"https://orcid.org/0000-0002-5197-7538","observed_orcids":["https://orcid.org/0000-0002-5197-7538"]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"M.M. Grzybowski","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085539196","display_name":"P. Wolska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"P. Wolska","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007448315","display_name":"Anna Maria Zdziarska","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"A.M. Zdziarska","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039135976","display_name":"Marcin Mazurkiewicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"M. Mazurkiewicz","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011878826","display_name":"Roman B\u0142aszczyk","orcid":"https://orcid.org/0000-0001-7348-9837","observed_orcids":["https://orcid.org/0000-0001-7348-9837"]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"R. Blaszczyk","raw_affiliation_strings":["Department of Chemistry, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069173513","display_name":"Julita Nowicka","orcid":"https://orcid.org/0000-0002-0596-9377","observed_orcids":["https://orcid.org/0000-0002-0596-9377"]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"J. Nowicka","raw_affiliation_strings":["Department of Chemistry, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059308069","display_name":"Anna Sosnowska","orcid":"https://orcid.org/0000-0002-8939-6157","observed_orcids":["https://orcid.org/0000-0002-8939-6157"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"A. Sosnowska","raw_affiliation_strings":["Department of Immunology, Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051155453","display_name":"Kavita Ramji","orcid":"https://orcid.org/0000-0002-3667-2146","observed_orcids":["https://orcid.org/0000-0002-3667-2146"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"K. Ramji","raw_affiliation_strings":["Department of Immunology, Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065430527","display_name":"Dominika Nowis","orcid":"https://orcid.org/0000-0003-2748-9523","observed_orcids":["https://orcid.org/0000-0003-2748-9523"]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]},{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"D. Nowis","raw_affiliation_strings":["Genomic Medicine, Medical University of Warsaw, Warsaw; Laboratory of Experimental Medicine, Centre of New Technologies, University of Warsaw, Warsaw, Poland","Genomic Medicine, Medical University of Warsaw, Warsaw","Laboratory of Experimental Medicine, Centre of New Technologies, University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genomic Medicine, Medical University of Warsaw, Warsaw; Laboratory of Experimental Medicine, Centre of New Technologies, University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]},{"raw_affiliation_string":"Genomic Medicine, Medical University of Warsaw, Warsaw","institution_ids":["https://openalex.org/I268303160"]},{"raw_affiliation_string":"Laboratory of Experimental Medicine, Centre of New Technologies, University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I4654613"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Golab","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I268303160","display_name":"Medical University of Warsaw","ror":"https://ror.org/04p2y4s44","country_code":"PL","type":"education","lineage":["https://openalex.org/I268303160"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"J. Golab","raw_affiliation_strings":["Department of Immunology, Medical University of Warsaw, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Medical University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I268303160"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021496114","display_name":"Adam Go\u0142\u0229biowski","orcid":"https://orcid.org/0000-0001-5960-2995","observed_orcids":["https://orcid.org/0000-0001-5960-2995"]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"A. Golebiowski","raw_affiliation_strings":["Department of Chemistry, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049004454","display_name":"Pawe\u0142 Dobrza\u0144ski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"P. Dobrzanski","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062063050","display_name":"Karolina Dzwonek","orcid":"https://orcid.org/0000-0002-9580-3863","observed_orcids":["https://orcid.org/0000-0002-9580-3863"]},"institutions":[{"id":"https://openalex.org/I4210141095","display_name":"OncoArendi Therapeutics (Poland)","ror":"https://ror.org/03q2tdj19","country_code":"PL","type":"company","lineage":["https://openalex.org/I4210141095"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"K. Dzwonek","raw_affiliation_strings":["Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, OncoArendi Therapeutics SA, Warsaw, Poland","institution_ids":["https://openalex.org/I4210141095"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5080,"currency":"USD","value_usd":5080},"apc_paid":null,"fwci":0.7853,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.72130617,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"28","issue":null,"first_page":"v418","last_page":"v418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Bacterial Cancer Therapy","score":0.08259999752044678,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.04969999939203262,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arginine-deprivation","display_name":"arginine deprivation","score":0.8529999852180481},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.8669999837875366},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.7099999785423279},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.796999990940094},{"id":"https://openalex.org/keywords/t-cell-proliferation","display_name":"T cell proliferation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/immunotherapy-resistance","display_name":"immunotherapy resistance","score":0.41100001335144043}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.718126654624939},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5677198767662048},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5321551561355591},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4836827218532562},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4792444705963135},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.47797128558158875},{"id":"https://openalex.org/C26291073","wikidata":"https://www.wikidata.org/wiki/Q310484","display_name":"Ex vivo","level":3,"score":0.46902647614479065},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.46593159437179565},{"id":"https://openalex.org/C164007495","wikidata":"https://www.wikidata.org/wiki/Q24721374","display_name":"Arginase","level":4,"score":0.45884406566619873},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3263806700706482},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2528122067451477},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.24282562732696533},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16418519616127014},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/annonc/mdx376.045","doi":"https://doi.org/10.1093/annonc/mdx376.045","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdx376.045","pdf_url":null,"source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},{"id":"doi:10.1093/annonc/mdx376.046","doi":"https://doi.org/10.1093/annonc/mdx376.046","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdx376.046","pdf_url":"https://academic.oup.com/annonc/article-pdf/28/suppl_5/mdx376.046/19940458/mdx376.046.pdf","source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/annonc/mdx376.045","doi":"https://doi.org/10.1093/annonc/mdx376.045","is_oa":true,"landing_page_url":"https://doi.org/10.1093/annonc/mdx376.045","pdf_url":null,"source":{"id":"https://openalex.org/S41454044","display_name":"Annals of Oncology","issn_l":"0923-7534","issn":["0923-7534","1569-8041"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2762932397.pdf","grobid_xml":"https://content.openalex.org/works/W2762932397.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2785798671","https://openalex.org/W2771527416","https://openalex.org/W3186885003","https://openalex.org/W4327895830","https://openalex.org/W4409633668","https://openalex.org/W3083480437","https://openalex.org/W2996370418","https://openalex.org/W2321069046","https://openalex.org/W2548879187","https://openalex.org/W3024126283"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2017-10-20T00:00:00"}