{"id":"https://openalex.org/W2762482003","doi":null,"title":"The initial report of the bloodwise tap clarity study combining ibrutinib and venetoclax in relapsed, refractory Cll shows acceptable safety and promising early indications of efficacy.","display_name":"The initial report of the bloodwise tap clarity study combining ibrutinib and venetoclax in relapsed, refractory Cll shows acceptable safety and promising early indications of efficacy.","publication_year":2017,"publication_date":"2017-06-26","ids":{"openalex":"https://openalex.org/W2762482003","mag":"2762482003"},"language":"en","primary_location":{"id":"mag:2762482003","doi":null,"is_oa":true,"landing_page_url":"https://christie.openrepository.com/handle/10541/620521","pdf_url":null,"source":{"id":"https://openalex.org/S2752781272","display_name":"Haematologica","issn_l":"0390-6078","issn":["0390-6078","1592-8721"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317774","host_organization_name":"Ferrata Storti Foundation","host_organization_lineage":["https://openalex.org/P4310317774"],"host_organization_lineage_names":["Ferrata Storti Foundation"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Haematologica","raw_type":null},"parent_works":[],"lineage":["https://openalex.org/W2762482003"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://christie.openrepository.com/handle/10541/620521","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031073857","display_name":"Peter Hillmen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Hillmen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001511648","display_name":"Andy C. Rawstron","orcid":"https://orcid.org/0000-0003-0798-9790","observed_orcids":["https://orcid.org/0000-0003-0798-9790"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andy C. Rawstron","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0798-9790","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110529429","display_name":"T Munir","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Munir","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019472985","display_name":"Kristian Brock","orcid":"https://orcid.org/0000-0002-3921-0166","observed_orcids":["https://orcid.org/0000-0002-3921-0166"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristian Brock","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3921-0166","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014424586","display_name":"S Vincente","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Vincente","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081996423","display_name":"Yolande Jefferson","orcid":"https://orcid.org/0009-0000-2549-5538","observed_orcids":["https://orcid.org/0009-0000-2549-5538"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yolande Jefferson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080416981","display_name":"Kathryn Paterson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathryn Paterson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026739355","display_name":"Julie Fox","orcid":"https://orcid.org/0000-0002-0583-8019","observed_orcids":["https://orcid.org/0000-0002-0583-8019"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julie Fox","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0583-8019","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067154165","display_name":"John G. Gribben","orcid":"https://orcid.org/0000-0002-8505-7430","observed_orcids":["https://orcid.org/0000-0002-8505-7430"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JG Gribben","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025217094","display_name":"Adrian John Clifton Bloor","orcid":"https://orcid.org/0000-0003-4550-220X","observed_orcids":["https://orcid.org/0000-0003-4550-220X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adrian Bloor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074839524","display_name":"Anna Schuh","orcid":"https://orcid.org/0000-0002-3938-8490","observed_orcids":["https://orcid.org/0000-0002-3938-8490"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Schuh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3938-8490","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5078295579","display_name":"Francesco Forconi","orcid":"https://orcid.org/0000-0002-2211-1831","observed_orcids":["https://orcid.org/0000-0002-2211-1831"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francesco Forconi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2211-1831","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2000,"currency":"EUR","value_usd":2157},"apc_paid":{"value":2000,"currency":"EUR","value_usd":2157},"fwci":0.8257,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.72725259,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"102","issue":null,"first_page":"311","last_page":"311"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ibrutinib","display_name":"ibrutinib","score":0.9739999771118164},{"id":"https://openalex.org/keywords/venetoclax","display_name":"venetoclax","score":1.0},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.8579999804496765},{"id":"https://openalex.org/keywords/relapsed-refractory-cll","display_name":"relapsed/refractory CLL","score":0.8199999928474426},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7639999985694885},{"id":"https://openalex.org/keywords/bruton-tyrosine-kinase-inhibitors","display_name":"BTK inhibitors","score":0.6039999723434448},{"id":"https://openalex.org/keywords/bcl2-inhibitors","display_name":"BCL-2 inhibitor","score":0.8870000243186951},{"id":"https://openalex.org/keywords/safety","display_name":"safety","score":0.503000020980835},{"id":"https://openalex.org/keywords/efficacy","display_name":"efficacy","score":0.8429999947547913}],"concepts":[{"id":"https://openalex.org/C2779878957","wikidata":"https://www.wikidata.org/wiki/Q5984881","display_name":"Ibrutinib","level":4,"score":0.9197089076042175},{"id":"https://openalex.org/C2779675984","wikidata":"https://www.wikidata.org/wiki/Q23671272","display_name":"Venetoclax","level":4,"score":0.9042856693267822},{"id":"https://openalex.org/C2777146004","wikidata":"https://www.wikidata.org/wiki/Q14949826","display_name":"CLARITY","level":2,"score":0.6955929398536682},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5831697583198547},{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.5194793939590454},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.43037599325180054},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36657601594924927},{"id":"https://openalex.org/C2777938653","wikidata":"https://www.wikidata.org/wiki/Q1088156","display_name":"Chronic lymphocytic leukemia","level":3,"score":0.26191475987434387},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.22990715503692627},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0740419328212738},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2762482003","doi":null,"is_oa":true,"landing_page_url":"https://christie.openrepository.com/handle/10541/620521","pdf_url":null,"source":{"id":"https://openalex.org/S2752781272","display_name":"Haematologica","issn_l":"0390-6078","issn":["0390-6078","1592-8721"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317774","host_organization_name":"Ferrata Storti Foundation","host_organization_lineage":["https://openalex.org/P4310317774"],"host_organization_lineage_names":["Ferrata Storti Foundation"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Haematologica","raw_type":null}],"best_oa_location":{"id":"mag:2762482003","doi":null,"is_oa":true,"landing_page_url":"https://christie.openrepository.com/handle/10541/620521","pdf_url":null,"source":{"id":"https://openalex.org/S2752781272","display_name":"Haematologica","issn_l":"0390-6078","issn":["0390-6078","1592-8721"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317774","host_organization_name":"Ferrata Storti Foundation","host_organization_lineage":["https://openalex.org/P4310317774"],"host_organization_lineage_names":["Ferrata Storti Foundation"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Haematologica","raw_type":null},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3024701913","https://openalex.org/W3038814322","https://openalex.org/W3111754803","https://openalex.org/W2911124342","https://openalex.org/W2962038803","https://openalex.org/W2942032188","https://openalex.org/W4413776810","https://openalex.org/W7222971886","https://openalex.org/W4413774236","https://openalex.org/W4310093704"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-10-20T00:00:00"}