{"id":"https://openalex.org/W2755869148","doi":"https://doi.org/10.23866/brnrev:2017-m0041","title":"Idiopathic Pulmonary Fibrosis: What Is the Best Treatment?","display_name":"Idiopathic Pulmonary Fibrosis: What Is the Best Treatment?","publication_year":2017,"publication_date":"2017-04-01","ids":{"openalex":"https://openalex.org/W2755869148","doi":"https://doi.org/10.23866/brnrev:2017-m0041","mag":"2755869148"},"language":"en","primary_location":{"id":"doi:10.23866/brnrev:2017-m0041","doi":"https://doi.org/10.23866/brnrev:2017-m0041","is_oa":true,"landing_page_url":"https://doi.org/10.23866/brnrev:2017-m0041","pdf_url":null,"source":{"id":"https://openalex.org/S4210170412","display_name":"Barcelona Respiratory Network","issn_l":"2385-7110","issn":["2385-7110","2462-3172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Barcelona Respiratory Network","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.23866/brnrev:2017-m0041","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100767595","display_name":"Fernando J. Mart\u00ednez","orcid":"https://orcid.org/0000-0002-2412-3182","observed_orcids":["https://orcid.org/0000-0002-2412-3182","https://orcid.org/0000-0003-4957-8869","https://orcid.org/0000-0001-8298-2703"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fernando J. Martinez","raw_affiliation_strings":["Division of Pulmonary and Critical Care Medicine, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary and Critical Care Medicine, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052471232","display_name":"Robert J. Kaner","orcid":"https://orcid.org/0000-0003-0527-576X","observed_orcids":["https://orcid.org/0000-0003-0527-576X"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert J. Kaner","raw_affiliation_strings":["Department of Genetic Medicine, Weill Cornell Medicine, New York, NY, USA","Division of Pulmonary and Critical Care Medicine, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Medicine, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Division of Pulmonary and Critical Care Medicine, and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101917088","display_name":"Xiaoping Wu","orcid":"https://orcid.org/0000-0002-6910-0718","observed_orcids":["https://orcid.org/0000-0002-6910-0718"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoping Wu","raw_affiliation_strings":["Department of Genetic Medicine, Weill Cornell Medicine, New York, NY, USA","Division of Pulmonary and Critical Care Medicine, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetic Medicine, Weill Cornell Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Division of Pulmonary and Critical Care Medicine, and","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2201,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.60661723,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"3","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/idiopathic-pulmonary-fibrosis","display_name":"idiopathic pulmonary fibrosis","score":1.0},{"id":"https://openalex.org/keywords/interstitial-lung-disease","display_name":"interstitial lung disease","score":0.6029999852180481},{"id":"https://openalex.org/keywords/pirfenidone","display_name":"pirfenidone","score":0.9179999828338623},{"id":"https://openalex.org/keywords/nintedanib","display_name":"nintedanib","score":1.0},{"id":"https://openalex.org/keywords/antifibrotic-agents","display_name":"antifibrotic agents","score":0.8920000195503235},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.9049999713897705},{"id":"https://openalex.org/keywords/incidence-trends","display_name":"incidence trends","score":0.5320000052452087},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.7889999747276306},{"id":"https://openalex.org/keywords/clinical-trials","display_name":"clinical trials","score":0.7070000171661377},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.4350000023841858}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6741372346878052},{"id":"https://openalex.org/C2778341716","wikidata":"https://www.wikidata.org/wiki/Q2290446","display_name":"Idiopathic pulmonary fibrosis","level":3,"score":0.6381645202636719},{"id":"https://openalex.org/C2781244666","wikidata":"https://www.wikidata.org/wiki/Q32446","display_name":"Pulmonary fibrosis","level":3,"score":0.5616731643676758},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4277043640613556},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.4026065468788147},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.16881999373435974}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.23866/brnrev:2017-m0041","doi":"https://doi.org/10.23866/brnrev:2017-m0041","is_oa":true,"landing_page_url":"https://doi.org/10.23866/brnrev:2017-m0041","pdf_url":null,"source":{"id":"https://openalex.org/S4210170412","display_name":"Barcelona Respiratory Network","issn_l":"2385-7110","issn":["2385-7110","2462-3172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Barcelona Respiratory Network","raw_type":"journal-article"},{"id":"doi:10.24875/brn.m17000009","doi":"https://doi.org/10.24875/brn.m17000009","is_oa":true,"landing_page_url":"https://doi.org/10.24875/brn.m17000009","pdf_url":null,"source":{"id":"https://openalex.org/S4210170412","display_name":"Barcelona Respiratory Network","issn_l":"2385-7110","issn":["2385-7110","2462-3172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Barcelona Respiratory Network","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.23866/brnrev:2017-m0041","doi":"https://doi.org/10.23866/brnrev:2017-m0041","is_oa":true,"landing_page_url":"https://doi.org/10.23866/brnrev:2017-m0041","pdf_url":null,"source":{"id":"https://openalex.org/S4210170412","display_name":"Barcelona Respiratory Network","issn_l":"2385-7110","issn":["2385-7110","2462-3172"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Barcelona Respiratory Network","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1569431722","https://openalex.org/W1757222072","https://openalex.org/W1801975325","https://openalex.org/W1938547050","https://openalex.org/W1969070671","https://openalex.org/W1970800979","https://openalex.org/W1983357763","https://openalex.org/W1990240660","https://openalex.org/W2003869191","https://openalex.org/W2005543326","https://openalex.org/W2011826235","https://openalex.org/W2018381516","https://openalex.org/W2049610833","https://openalex.org/W2050976366","https://openalex.org/W2051879911","https://openalex.org/W2060427373","https://openalex.org/W2079311676","https://openalex.org/W2085604666","https://openalex.org/W2101548854","https://openalex.org/W2102969338","https://openalex.org/W2103221430","https://openalex.org/W2104766198","https://openalex.org/W2106320546","https://openalex.org/W2108830193","https://openalex.org/W2112949206","https://openalex.org/W2138871107","https://openalex.org/W2142941142","https://openalex.org/W2143487186","https://openalex.org/W2145491879","https://openalex.org/W2146127863","https://openalex.org/W2146139012","https://openalex.org/W2152974152","https://openalex.org/W2161655061","https://openalex.org/W2167383172","https://openalex.org/W2168666423","https://openalex.org/W2208096782","https://openalex.org/W2235270260","https://openalex.org/W2300645540","https://openalex.org/W2315538569","https://openalex.org/W2315878550","https://openalex.org/W2331647948","https://openalex.org/W2333432793","https://openalex.org/W2342846323","https://openalex.org/W2409881902","https://openalex.org/W2413745624","https://openalex.org/W2462000645","https://openalex.org/W2474839550","https://openalex.org/W2519077833","https://openalex.org/W2524005801","https://openalex.org/W2550523848","https://openalex.org/W2560640434","https://openalex.org/W2577072690","https://openalex.org/W3152401400","https://openalex.org/W3198454324","https://openalex.org/W4231226497","https://openalex.org/W4252692455","https://openalex.org/W4256454582","https://openalex.org/W4296612182","https://openalex.org/W7073607420"],"related_works":["https://openalex.org/W2785306980","https://openalex.org/W2741974392","https://openalex.org/W2372585578","https://openalex.org/W2914173187","https://openalex.org/W2981640996","https://openalex.org/W2583306595","https://openalex.org/W2476358783","https://openalex.org/W2726475926","https://openalex.org/W4399416617","https://openalex.org/W2765883004"],"abstract_inverted_index":{"Idiopathic":[0],"pulmonary":[1],"fibrosis":[2],"(IPF)":[3],"is":[4,16,35],"a":[5],"disease":[6,93],"of":[7,44,61,69,77],"chronic":[8],"progressive":[9],"interstitial":[10],"pneumonia":[11],"limited":[12],"to":[13,38,56,90],"the":[14,33,45,75,92,96,106,111],"lungs.There":[15],"growing":[17],"interest":[18],"in":[19,29],"this":[20],"disorder":[21],"as":[22,102],"its":[23,62],"incidence":[24],"has":[25,53],"increased":[26,42],"over":[27,105],"time":[28],"most":[30],"countries":[31],"around":[32],"world.This":[34],"likely":[36],"related":[37],"an":[39,58],"aging":[40],"population,":[41],"awareness":[43],"disease,":[46],"and":[47,64,82,115,121],"increasingly":[48],"sensitive":[49],"imaging":[50],"technology.Considerable":[51],"energy":[52],"been":[54,72,100],"devoted":[55],"creating":[57],"improved":[59],"understanding":[60],"pathogenesis":[63],"developing":[65],"novel":[66],"therapies.Although":[67],"dozens":[68],"drugs":[70,97],"have":[71,99],"studied":[73],"for":[74],"treatment":[76],"IPF,":[78],"only":[79],"two,":[80],"pirfenidone":[81,114],"nintedanib,":[83,116],"are":[84],"currently":[85,112],"recommended":[86,113],"by":[87],"international":[88],"guidelines":[89],"slow":[91],"progression.We":[94],"review":[95],"that":[98],"evaluated":[101],"IPF":[103],"therapy":[104],"past":[107],"three":[108],"decades,":[109],"including":[110],"note":[117],"ongoing":[118],"clinical":[119],"trials":[120],"provide":[122],"insights":[123],"into":[124],"future":[125],"directions.(BRN":[126],"Rev.":[127]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2017-09-25T00:00:00"}