{"id":"https://openalex.org/W2750057798","doi":"https://doi.org/10.1111/neup.12409","title":"Clinicopathologic features and pathogenesis of melanocytic colonization in atypical meningioma","display_name":"Clinicopathologic features and pathogenesis of melanocytic colonization in atypical meningioma","publication_year":2017,"publication_date":"2017-08-18","ids":{"openalex":"https://openalex.org/W2750057798","doi":"https://doi.org/10.1111/neup.12409","mag":"2750057798","pmid":"https://pubmed.ncbi.nlm.nih.gov/28833600"},"language":"en","primary_location":{"id":"doi:10.1111/neup.12409","doi":"https://doi.org/10.1111/neup.12409","is_oa":false,"landing_page_url":"https://doi.org/10.1111/neup.12409","pdf_url":null,"source":{"id":"https://openalex.org/S43667197","display_name":"Neuropathology","issn_l":"0919-6544","issn":["0919-6544","1440-1789"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033334976","display_name":"Mitra Dehghan Harati","orcid":"https://orcid.org/0000-0001-7611-1653","observed_orcids":["https://orcid.org/0000-0001-7611-1653"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitra Dehghan Harati","raw_affiliation_strings":["Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":"https://orcid.org/0000-0001-7611-1653","affiliations":[{"raw_affiliation_string":"Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111763154","display_name":"Andrew Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Yu","raw_affiliation_strings":["Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027198967","display_name":"Shino Magaki","orcid":"https://orcid.org/0000-0003-0433-5759","observed_orcids":["https://orcid.org/0000-0003-0433-5759"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shino D. Magaki","raw_affiliation_strings":["Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035732644","display_name":"Mari A. Perez-Rosendahl","orcid":"https://orcid.org/0000-0002-8786-1932","observed_orcids":["https://orcid.org/0000-0002-8786-1932"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mari Perez\u2010Rosendahl","raw_affiliation_strings":["Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002911267","display_name":"Kyuseok Im","orcid":"https://orcid.org/0000-0002-5030-4681","observed_orcids":["https://orcid.org/0000-0002-5030-4681","https://orcid.org/0009-0009-0765-350X"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyuseok Im","raw_affiliation_strings":["Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035252512","display_name":"Young K. Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Young K. Park","raw_affiliation_strings":["Department of Radiological Sciences, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiological Sciences, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109878675","display_name":"Marvin Bergsneider","orcid":"https://orcid.org/0000-0001-6423-5480","observed_orcids":["https://orcid.org/0000-0001-6423-5480"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marvin Bergsneider","raw_affiliation_strings":["Department of Neurosurgery, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016190247","display_name":"William H. Yong","orcid":"https://orcid.org/0000-0002-0879-0209","observed_orcids":["https://orcid.org/0000-0002-0879-0209"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"William H. Yong","raw_affiliation_strings":["Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Neuropathology, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA University of California, Los Angeles, California, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5016190247"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":3400,"currency":"USD","value_usd":3400},"apc_paid":null,"fwci":0.1858,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.50430626,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"38","issue":"1","first_page":"54","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11600","display_name":"Brain Metastases and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atypical-meningioma","display_name":"atypical meningioma","score":0.9800000190734863},{"id":"https://openalex.org/keywords/dendritic-melanocytes","display_name":"dendritic melanocytes","score":0.9700000286102295},{"id":"https://openalex.org/keywords/brain-invasion","display_name":"brain invasion","score":0.7160000205039978},{"id":"https://openalex.org/keywords/pineal-region-tumors","display_name":"pineal region tumors","score":0.7749999761581421},{"id":"https://openalex.org/keywords/tentorial-incisura","display_name":"tentorial incisura","score":0.8339999914169312},{"id":"https://openalex.org/keywords/c-kit","display_name":"CD117","score":0.8769999742507935},{"id":"https://openalex.org/keywords/stem-cell-factor","display_name":"stem cell factor","score":0.9980000257492065},{"id":"https://openalex.org/keywords/basic-fibroblast-growth-factor","display_name":"basic fibroblast growth factor","score":1.0},{"id":"https://openalex.org/keywords/melanocyte-migration","display_name":"melanocyte migration","score":0.8640000224113464},{"id":"https://openalex.org/keywords/hydrocephalus","display_name":"hydrocephalus","score":0.5889999866485596},{"id":"https://openalex.org/keywords/diplopia","display_name":"diplopia","score":0.8489999771118164},{"id":"https://openalex.org/keywords/non-caucasian-patients","display_name":"non-Caucasian patients","score":0.703000009059906},{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.46399998664855957}],"concepts":[{"id":"https://openalex.org/C2779160599","wikidata":"https://www.wikidata.org/wiki/Q369157","display_name":"Meningioma","level":2,"score":0.7188787460327148},{"id":"https://openalex.org/C2779769559","wikidata":"https://www.wikidata.org/wiki/Q247101","display_name":"Melanocyte","level":3,"score":0.5811371207237244},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5263458490371704},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5116958618164062},{"id":"https://openalex.org/C2778134817","wikidata":"https://www.wikidata.org/wiki/Q193003","display_name":"Hydrocephalus","level":2,"score":0.511683464050293},{"id":"https://openalex.org/C2776403516","wikidata":"https://www.wikidata.org/wiki/Q268930","display_name":"Meninges","level":2,"score":0.4245578348636627},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.19212457537651062},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.176161527633667},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1636349856853485}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008544","descriptor_name":"Melanocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008577","descriptor_name":"Meningeal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008579","descriptor_name":"Meningioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/neup.12409","doi":"https://doi.org/10.1111/neup.12409","is_oa":false,"landing_page_url":"https://doi.org/10.1111/neup.12409","pdf_url":null,"source":{"id":"https://openalex.org/S43667197","display_name":"Neuropathology","issn_l":"0919-6544","issn":["0919-6544","1440-1789"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropathology","raw_type":"journal-article"},{"id":"pmid:28833600","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28833600","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropathology : official journal of the Japanese Society of Neuropathology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W160183083","https://openalex.org/W1940921051","https://openalex.org/W1965852462","https://openalex.org/W1982394778","https://openalex.org/W1982794126","https://openalex.org/W2000892993","https://openalex.org/W2001915960","https://openalex.org/W2015586822","https://openalex.org/W2022308897","https://openalex.org/W2027838880","https://openalex.org/W2039637765","https://openalex.org/W2046895068","https://openalex.org/W2071654890","https://openalex.org/W2076411235","https://openalex.org/W2079034149","https://openalex.org/W2082210573","https://openalex.org/W2082390387","https://openalex.org/W2088174241","https://openalex.org/W2091024530","https://openalex.org/W2131721978","https://openalex.org/W2183778377","https://openalex.org/W2475137774","https://openalex.org/W2537309476","https://openalex.org/W2624094894"],"related_works":["https://openalex.org/W2039637765","https://openalex.org/W2137682865","https://openalex.org/W2015586822","https://openalex.org/W2177194616","https://openalex.org/W2616393574","https://openalex.org/W2126431105","https://openalex.org/W2003522016","https://openalex.org/W3154005070","https://openalex.org/W4256008870","https://openalex.org/W7097139386"],"abstract_inverted_index":{"Only":[0],"two":[1,116],"prior":[2],"cases":[3,117],"of":[4,62,125,158,194,214,260,267,289],"benign":[5],"dendritic":[6,216,235],"melanocytes":[7,160,217,236],"colonizing":[8],"a":[9,16,48,107,156],"meningioma":[10,110,174],"have":[11],"been":[12],"reported.":[13],"We":[14,151],"add":[15],"third":[17],"case,":[18],"describe":[19],"clinicopathologic":[20],"features":[21],"shared":[22],"by":[23],"the":[24,28,63,73,101,119,159,173,195,203,207,215,265,281],"three,":[25],"and":[26,44,72,85,98,167,262],"elucidate":[27],"risk":[29,137],"factors":[30],"for":[31,138,149],"this":[32,268],"very":[33],"rare":[34],"phenomenon.":[35],"A":[36],"29":[37],"year-old":[38],"Hispanic":[39],"woman":[40],"presented":[41,79],"with":[42,83,111,192,233],"headache":[43],"hydrocephalus.":[45],"MRI":[46,86],"showed":[47,87,106],"lobulated":[49],"enhancing":[50,89],"pineal":[51],"region":[52],"mass":[53,64,91],"measuring":[54,92],"41":[55],"mm":[56,94],"in":[57,95,118,155,172,180,228,264,280],"greatest":[58,96],"dimension.":[59],"Subtotal":[60,104],"resection":[61,105],"demonstrated":[65],"an":[66,88],"atypical":[67,109,122],"meningioma,":[68],"WHO":[69],"grade":[70],"II,":[71],"patient":[74],"subsequently":[75],"underwent":[76],"radiotherapy.":[77],"She":[78],"4":[80],"years":[81,247,251],"later":[82],"diplopia,":[84],"extra-axial":[90],"47":[93],"dimension":[97],"centered":[99],"on":[100],"tentorial":[102],"incisura.":[103],"brain-invasive":[108],"melanocytic":[112,139,275],"colonization.":[113,240],"The":[114,241,258],"previous":[115],"literature":[120],"were":[121,225,256],"meningiomas,":[123],"one":[124],"which":[126],"was":[127],"also":[128,199,278],"brain":[129,190,231],"invasive.":[130],"Atypical":[131],"meningiomas":[132,227,286],"may":[133,184,198,237,277],"be":[134,147,185,272],"at":[135],"particular":[136],"colonization":[140,276],"as":[141,161,163],"they":[142],"upregulate":[143],"molecules":[144],"known":[145],"to":[146,239,249,271],"chemoattractants":[148],"melanocytes.":[150],"detected":[152],"c-Kit":[153],"expression":[154],"minority":[157],"well":[162],"stem":[164],"cell":[165],"factor":[166,171],"basic":[168],"fibroblast":[169],"growth":[170],"cells,":[175],"suggesting":[176],"that":[177,221],"mechanisms":[178],"implicated":[179],"normal":[181],"melanocyte":[182],"migration":[183,201],"involved.":[186],"In":[187],"some":[188],"cases,":[189],"invasion":[191],"disruption":[193],"leptomeningeal":[196],"barrier":[197],"facilitate":[200],"from":[202,245],"subarachnoid":[204],"space":[205],"into":[206],"tumor.":[208],"Whether":[209,274],"there":[210],"is":[211,218],"low-level":[212],"proliferation":[213],"unclear.":[219],"Given":[220],"all":[222],"three":[223,254],"patients":[224,255],"non-Caucasian,":[226],"persons":[229],"and/or":[230],"regions":[232],"increased":[234],"predispose":[238],"age":[242],"range":[243],"spanned":[244],"6":[246],"old":[248],"70":[250],"old.":[252],"All":[253],"female.":[257],"role":[259],"gender":[261],"estrogen":[263],"pathogenesis":[266],"entity":[269],"remains":[270],"clarified.":[273],"occur":[279],"more":[282],"common":[283],"Grade":[284],"I":[285],"awaits":[287],"identification":[288],"additional":[290],"cases.":[291]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-08-31T00:00:00"}