{"id":"https://openalex.org/W2748574331","doi":"https://doi.org/10.4274/jcrpe.4930","title":"Effect of Intrahepatic Cholestasis of Pregnancy on Neonatal Birth Weight: A Meta-Analysis","display_name":"Effect of Intrahepatic Cholestasis of Pregnancy on Neonatal Birth Weight: A Meta-Analysis","publication_year":2017,"publication_date":"2017-08-21","ids":{"openalex":"https://openalex.org/W2748574331","doi":"https://doi.org/10.4274/jcrpe.4930","mag":"2748574331","pmid":"https://pubmed.ncbi.nlm.nih.gov/28825589","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5838371"},"language":"en","primary_location":{"id":"doi:10.4274/jcrpe.4930","doi":"https://doi.org/10.4274/jcrpe.4930","is_oa":true,"landing_page_url":"https://doi.org/10.4274/jcrpe.4930","pdf_url":"https://doi.org/10.4274/jcrpe.4930","source":{"id":"https://openalex.org/S156675542","display_name":"Journal of Clinical Research in Pediatric Endocrinology","issn_l":"1308-5727","issn":["1308-5727","1308-5735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","poland-40","russia-white-list-2","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Research in Pediatric Endocrinology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.4274/jcrpe.4930","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100361289","display_name":"Li Li","orcid":"https://orcid.org/0000-0002-9835-9569","observed_orcids":["https://orcid.org/0000-0002-9835-9569"]},"institutions":[{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Li","raw_affiliation_strings":["First Affiliated Hospital of Anhui Medical University, Department of Obstetrics and Gynecology, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Affiliated Hospital of Anhui Medical University, Department of Obstetrics and Gynecology, Hefei, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113802677","display_name":"Yuan-Hua Chen","orcid":"https://orcid.org/0009-0003-0684-1222","observed_orcids":["https://orcid.org/0009-0003-0684-1222"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan-Hua Chen","raw_affiliation_strings":["Anhui Medical University, Department of Histology and Embryology, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Medical University, Department of Histology and Embryology, Hefei, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100540675","display_name":"Yuan-Yuan Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan-Yuan Yang","raw_affiliation_strings":["First Affiliated Hospital of Anhui Medical University, Department of Obstetrics and Gynecology, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Affiliated Hospital of Anhui Medical University, Department of Obstetrics and Gynecology, Hefei, China","institution_ids":["https://openalex.org/I4210136596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100331595","display_name":"Lin Cong","orcid":"https://orcid.org/0000-0002-4727-6472","observed_orcids":["https://orcid.org/0000-0002-4727-6472"]},"institutions":[{"id":"https://openalex.org/I4210136596","display_name":"First Affiliated Hospital of Anhui Medical University","ror":"https://ror.org/03t1yn780","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210136596"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lin Cong","raw_affiliation_strings":["First Affiliated Hospital of Anhui Medical University, Department of Obstetrics and Gynecology, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Affiliated Hospital of Anhui Medical University, Department of Obstetrics and Gynecology, Hefei, China","institution_ids":["https://openalex.org/I4210136596"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5100331595"],"corresponding_institution_ids":["https://openalex.org/I4210136596"],"apc_list":{"value":100,"currency":"USD","value_usd":100},"apc_paid":{"value":100,"currency":"USD","value_usd":100},"fwci":0.2494,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.2326969,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"1","first_page":"38","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10453","display_name":"Maternal and Perinatal Health Interventions","score":0.0763000026345253,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":0.0640999972820282,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intrahepatic-cholestasis-of-pregnancy","display_name":"intrahepatic cholestasis of pregnancy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/birth-weight","display_name":"birth weight","score":0.9909999966621399},{"id":"https://openalex.org/keywords/low-birth-weight","display_name":"low birth weight","score":0.8140000104904175},{"id":"https://openalex.org/keywords/pregnancy-complications","display_name":"pregnancy complications","score":0.7710000276565552}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8959952592849731},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.7902814149856567},{"id":"https://openalex.org/C66322754","wikidata":"https://www.wikidata.org/wiki/Q4128476","display_name":"Birth weight","level":3,"score":0.7424802780151367},{"id":"https://openalex.org/C2780439572","wikidata":"https://www.wikidata.org/wiki/Q919364","display_name":"Publication bias","level":3,"score":0.6851571202278137},{"id":"https://openalex.org/C2779083892","wikidata":"https://www.wikidata.org/wiki/Q6692979","display_name":"Low birth weight","level":3,"score":0.6042823791503906},{"id":"https://openalex.org/C2779224579","wikidata":"https://www.wikidata.org/wiki/Q60195073","display_name":"Cholestasis of pregnancy","level":4,"score":0.5817997455596924},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5676417350769043},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5566295385360718},{"id":"https://openalex.org/C82605166","wikidata":"https://www.wikidata.org/wiki/Q967190","display_name":"Funnel plot","level":4,"score":0.533180296421051},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5210278034210205},{"id":"https://openalex.org/C2778593092","wikidata":"https://www.wikidata.org/wiki/Q1075923","display_name":"Cholestasis","level":2,"score":0.4418606758117676},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.2660970091819763},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2286321520805359},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001724","descriptor_name":"Birth Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002780","descriptor_name":"Cholestasis, Intrahepatic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.4274/jcrpe.4930","doi":"https://doi.org/10.4274/jcrpe.4930","is_oa":true,"landing_page_url":"https://doi.org/10.4274/jcrpe.4930","pdf_url":"https://doi.org/10.4274/jcrpe.4930","source":{"id":"https://openalex.org/S156675542","display_name":"Journal of Clinical Research in Pediatric Endocrinology","issn_l":"1308-5727","issn":["1308-5727","1308-5735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","poland-40","russia-white-list-2","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Research in Pediatric Endocrinology","raw_type":"journal-article"},{"id":"pmid:28825589","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28825589","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical research in pediatric endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5838371","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5838371/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Res Pediatr Endocrinol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.4274/jcrpe.4930","doi":"https://doi.org/10.4274/jcrpe.4930","is_oa":true,"landing_page_url":"https://doi.org/10.4274/jcrpe.4930","pdf_url":"https://doi.org/10.4274/jcrpe.4930","source":{"id":"https://openalex.org/S156675542","display_name":"Journal of Clinical Research in Pediatric Endocrinology","issn_l":"1308-5727","issn":["1308-5727","1308-5735"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","medline","poland-40","russia-white-list-2","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Research in Pediatric Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2748574331.pdf","grobid_xml":"https://content.openalex.org/works/W2748574331.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W13665027","https://openalex.org/W1852384701","https://openalex.org/W1972303630","https://openalex.org/W1975161517","https://openalex.org/W1975358468","https://openalex.org/W1985390921","https://openalex.org/W1987717581","https://openalex.org/W1997977792","https://openalex.org/W1998874376","https://openalex.org/W2030042013","https://openalex.org/W2035142208","https://openalex.org/W2040780806","https://openalex.org/W2043385334","https://openalex.org/W2058864990","https://openalex.org/W2061899239","https://openalex.org/W2065794433","https://openalex.org/W2066403150","https://openalex.org/W2102257039","https://openalex.org/W2113724813","https://openalex.org/W2116475791","https://openalex.org/W2121957461","https://openalex.org/W2161224665","https://openalex.org/W2294982499","https://openalex.org/W2313257192","https://openalex.org/W2316937565","https://openalex.org/W2402005743","https://openalex.org/W2417939770","https://openalex.org/W2487274461","https://openalex.org/W2574444842"],"related_works":["https://openalex.org/W2113724813","https://openalex.org/W2349488453","https://openalex.org/W4407364141","https://openalex.org/W4399325242","https://openalex.org/W4396975518","https://openalex.org/W2380264848","https://openalex.org/W2376303118","https://openalex.org/W4411894086","https://openalex.org/W2383165620","https://openalex.org/W4411466770"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"the":[3,33,62,97,102,106,114,132,138,142,150],"effect":[4],"of":[5,8,25,64,73],"intrahepatic":[6],"cholestasis":[7],"pregnancy":[9],"(ICP)":[10],"on":[11,28,85],"neonatal":[12,86],"birth":[13,87,103,139,163,182],"weight.":[14],"METHODS:":[15],"Potential":[16,52],"articles":[17],"were":[18,40,76,168],"identified":[19],"by":[20],"searching":[21],"PubMed":[22],"and":[23,47,61,67,91],"Web":[24],"Science":[26],"databases":[27],"April":[29],"30th,":[30],"2017.":[31],"Using":[32],"Mantel-Haenszel":[34],"random-effects":[35],"or":[36],"fixed-effects":[37],"model,":[38],"outcomes":[39],"summarized":[41],"through":[42],"weighted":[43],"mean":[44],"difference":[45],"(WMD)":[46],"95%":[48,157],"confidence":[49],"intervals":[50],"(CI).":[51],"publication":[53],"bias":[54],"was":[55,109,121,146],"tested":[56],"using":[57],"a":[58,180],"funnel":[59],"plot":[60],"methods":[63],"Egger's":[65],"regression":[66],"Begg's":[68],"test.":[69],"RESULTS:":[70],"A":[71],"total":[72],"eight":[74],"studies":[75,82,99,135],"included":[77],"in":[78,89,105,113,141,149,165,171],"our":[79],"meta-analysis.":[80],"Six":[81],"reported":[83],"data":[84,95,130],"weight":[88,104,140,183],"ICP":[90,107,144,152,166,176],"control":[92,115],"pregnancies.":[93,173],"Pooled":[94],"from":[96,131],"six":[98],"showed":[100],"that":[101,137],"group":[108,145,153],"significantly":[110],"lighter":[111],"than":[112,148,170,184],"group.":[116],"The":[117],"overall":[118],"pooled":[119,129],"WMD":[120],"-175":[122],"g":[123],"(95%":[124],"CI:":[125,158],"-301,":[126],"-48).":[127],"Meanwhile,":[128],"other":[133],"two":[134],"indicated":[136],"late-onset":[143,185],"heavier":[147],"early-onset":[151,175],"(WMD:":[154],"267":[155],"g,":[156],"168,":[159],"366).":[160],"CONCLUSION:":[161],"Neonatal":[162],"weights":[164],"pregnancies":[167],"lower":[169,181],"normal":[172],"Furthermore,":[174],"is":[177],"associated":[178],"with":[179],"ICP.":[186]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2017-08-31T00:00:00"}