{"id":"https://openalex.org/W2747561575","doi":"https://doi.org/10.1007/s00268-017-4170-9","title":"Liver Function, Quantified by LiMAx Test, After Major Abdominal Surgery. Comparison Between Open and Laparoscopic Approach","display_name":"Liver Function, Quantified by LiMAx Test, After Major Abdominal Surgery. Comparison Between Open and Laparoscopic Approach","publication_year":2017,"publication_date":"2017-08-24","ids":{"openalex":"https://openalex.org/W2747561575","doi":"https://doi.org/10.1007/s00268-017-4170-9","mag":"2747561575","pmid":"https://pubmed.ncbi.nlm.nih.gov/28840295"},"language":"en","primary_location":{"id":"doi:10.1007/s00268-017-4170-9","doi":"https://doi.org/10.1007/s00268-017-4170-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00268-017-4170-9","pdf_url":null,"source":{"id":"https://openalex.org/S60318618","display_name":"World Journal of Surgery","issn_l":"0364-2313","issn":["0364-2313","1432-2323"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067178341","display_name":"Magnus Friedrich Kaffarnik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Magnus Kaffarnik","raw_affiliation_strings":["Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033687422","display_name":"Gabriel Stoeger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gabriel Stoeger","raw_affiliation_strings":["Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047436844","display_name":"Julia Liebich","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julia Liebich","raw_affiliation_strings":["Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014757338","display_name":"Christian Grieser","orcid":"https://orcid.org/0000-0002-1102-9648","observed_orcids":["https://orcid.org/0000-0002-1102-9648"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Grieser","raw_affiliation_strings":["Department of Radiology Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085883112","display_name":"Johann Pratschke","orcid":"https://orcid.org/0000-0001-9839-1369","observed_orcids":["https://orcid.org/0000-0001-9839-1369"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Johann Pratschke","raw_affiliation_strings":["Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany","institution_ids":["https://openalex.org/I7877124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112309580","display_name":"Martin Stockmann","orcid":"https://orcid.org/0000-0003-0764-5242","observed_orcids":["https://orcid.org/0000-0003-0764-5242"]},"institutions":[{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Stockmann","raw_affiliation_strings":["Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic of Surgery, Campus Mitte/Virchow Klinikum, Department of Surgery Charite\u2010Universit\u00e4tsmedizin Berlin Berlin Germany","institution_ids":["https://openalex.org/I7877124"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5067178341"],"corresponding_institution_ids":["https://openalex.org/I7877124"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":1.1108,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.75424778,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"42","issue":"2","first_page":"557","last_page":"566"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.2142000049352646,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12020","display_name":"Enhanced Recovery After Surgery","score":0.2142000049352646,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.17069999873638153,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.13379999995231628,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/limax-test","display_name":"LiMAx test","score":0.9179999828338623},{"id":"https://openalex.org/keywords/liver-function","display_name":"liver function","score":0.6869999766349792},{"id":"https://openalex.org/keywords/major-abdominal-surgery","display_name":"major abdominal surgery","score":0.9660000205039978},{"id":"https://openalex.org/keywords/laparoscopic-surgery","display_name":"laparoscopic surgery","score":0.8610000014305115},{"id":"https://openalex.org/keywords/open-laparotomy","display_name":"open laparotomy","score":0.9010000228881836},{"id":"https://openalex.org/keywords/systemic-inflammatory-response-syndrome","display_name":"systemic inflammatory response syndrome","score":0.9190000295639038},{"id":"https://openalex.org/keywords/hepatic-blood-flow","display_name":"hepatic blood flow","score":0.8640000224113464},{"id":"https://openalex.org/keywords/upper-abdominal-surgery","display_name":"upper abdominal surgery","score":0.7379999756813049},{"id":"https://openalex.org/keywords/postoperative-liver-injury","display_name":"postoperative liver injury","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8912926316261292},{"id":"https://openalex.org/C2780120127","wikidata":"https://www.wikidata.org/wiki/Q743664","display_name":"Abdominal surgery","level":2,"score":0.8275219798088074},{"id":"https://openalex.org/C2780778865","wikidata":"https://www.wikidata.org/wiki/Q1130374","display_name":"Laparotomy","level":2,"score":0.6876203417778015},{"id":"https://openalex.org/C2777010666","wikidata":"https://www.wikidata.org/wiki/Q1498222","display_name":"Vascular surgery","level":3,"score":0.5768038630485535},{"id":"https://openalex.org/C160022790","wikidata":"https://www.wikidata.org/wiki/Q2964004","display_name":"Cardiothoracic surgery","level":2,"score":0.5746628642082214},{"id":"https://openalex.org/C2778789114","wikidata":"https://www.wikidata.org/wiki/Q235007","display_name":"Cardiac surgery","level":2,"score":0.532709538936615},{"id":"https://openalex.org/C2780047204","wikidata":"https://www.wikidata.org/wiki/Q675754","display_name":"Laparoscopy","level":2,"score":0.5238021612167358},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5201488137245178},{"id":"https://openalex.org/C2778426790","wikidata":"https://www.wikidata.org/wiki/Q1649580","display_name":"Organ dysfunction","level":3,"score":0.41285353899002075},{"id":"https://openalex.org/C2776111594","wikidata":"https://www.wikidata.org/wiki/Q675754","display_name":"Laparoscopic surgery","level":3,"score":0.41055089235305786},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3309493362903595},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.2679441571235657}],"mesh":[{"descriptor_ui":"D000005","descriptor_name":"Abdomen","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006499","descriptor_name":"Hepatic Artery","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008102","descriptor_name":"Liver Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008111","descriptor_name":"Liver Function Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010535","descriptor_name":"Laparoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011169","descriptor_name":"Portal Vein","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018616","descriptor_name":"Ultrasonography, Doppler, Duplex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018746","descriptor_name":"Systemic Inflammatory Response Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00268-017-4170-9","doi":"https://doi.org/10.1007/s00268-017-4170-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00268-017-4170-9","pdf_url":null,"source":{"id":"https://openalex.org/S60318618","display_name":"World Journal of Surgery","issn_l":"0364-2313","issn":["0364-2313","1432-2323"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Surgery","raw_type":"journal-article"},{"id":"pmid:28840295","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28840295","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of surgery","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W10055254","https://openalex.org/W43789638","https://openalex.org/W71325827","https://openalex.org/W1862726000","https://openalex.org/W1958083356","https://openalex.org/W1969578797","https://openalex.org/W1973935956","https://openalex.org/W1975463665","https://openalex.org/W1979109569","https://openalex.org/W1980319095","https://openalex.org/W1982301103","https://openalex.org/W1991864206","https://openalex.org/W1992834839","https://openalex.org/W1994642617","https://openalex.org/W1998066141","https://openalex.org/W1999670883","https://openalex.org/W2004536137","https://openalex.org/W2044120253","https://openalex.org/W2056560182","https://openalex.org/W2077237485","https://openalex.org/W2078833807","https://openalex.org/W2084427346","https://openalex.org/W2090819282","https://openalex.org/W2096998881","https://openalex.org/W2119363042","https://openalex.org/W2121464977","https://openalex.org/W2129681898","https://openalex.org/W2132863212","https://openalex.org/W2150055309","https://openalex.org/W2209079252","https://openalex.org/W2398548097"],"related_works":["https://openalex.org/W3177450258","https://openalex.org/W3036919851","https://openalex.org/W2746619821","https://openalex.org/W2808219743","https://openalex.org/W2567279555","https://openalex.org/W6965190534","https://openalex.org/W4297448072","https://openalex.org/W2511939854","https://openalex.org/W2119363042","https://openalex.org/W2356312266"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Major":[1],"abdominal":[2,56,83,199],"surgery":[3,200],"may":[4],"lead":[5],"to":[6,212],"a":[7,13,22,36,151,165,180],"systemic":[8],"inflammatory":[9],"response":[10],"(SIRS)":[11],"with":[12],"risk":[14],"of":[15,46,122,224],"organ":[16],"failure.":[17],"One":[18],"possible":[19],"trigger":[20],"for":[21,81],"postoperative":[23,98,228],"hepatic":[24,29],"dysfunction":[25,48,196,226],"is":[26,201],"an":[27,209],"altered":[28],"blood":[30,183],"flow":[31],"during":[32],"SIRS,":[33],"resulting":[34],"in":[35,222],"decreased":[37,139],"oxygen":[38],"delivery.":[39],"This":[40],"pilot":[41],"study":[42],"investigated":[43,68],"the":[44,51,120],"role":[45],"liver":[47,182,214,225],"measured":[49,112],"by":[50,97,150],"LiMAx":[52,86,137,206],"test":[53,207],"after":[54,197],"major":[55,198],"surgery,":[57],"focussing":[58],"on":[59,141,168],"open":[60],"and":[61,73,89,104,108,177,190,203,217,227],"laparoscopic":[62,218],"surgical":[63],"approaches.":[64],"METHODS:":[65],"We":[66],"prospectively":[67],"25":[69],"patients":[70],"(7":[71],"females":[72],"18":[74],"males,":[75],"age":[76],"range":[77],"55-72":[78],"years)":[79],"scheduled":[80],"upper":[82],"surgery.":[84],"The":[85,124,205],"test,":[87],"ICG-PDR":[88,178],"duplex":[90],"sonography":[91,176],"were":[92,111,117,192],"carried":[93],"out":[94],"preoperatively,":[95],"followed":[96,149],"days":[99],"(PODs)":[100],"1,":[101],"3,":[102],"5":[103],"10.":[105],"Laboratory":[106],"parameters":[107,110,116],"clinical":[109],"daily.":[113],"Clinical":[114],"outcome":[115],"examined":[118],"at":[119,154],"end":[121],"treatment.":[123],"population":[125],"was":[126],"divided":[127],"into":[128],"group":[129,133,188],"A":[130,189],"(laparotomy)":[131],"versus":[132],"B":[134,191],"(laparoscopy).":[135],"RESULTS:":[136],"values":[138],"significantly":[140],"POD":[142,155,169],"1":[143,170],"(290":[144],"\u00b5g/kg/h,":[145,158],"P":[146,159,172],"<":[147,173],"0.001),":[148],"significant":[152,166],"increase":[153,167],"3":[156],"(348":[157],"=":[160],"0.013).":[161],"Only":[162],"INR":[163],"showed":[164],"(1.26,":[171],"0.001).":[174],"Duplex":[175],"revealed":[179],"hyper-dynamic":[181],"flow.":[184],"No":[185],"differences":[186],"between":[187],"found.":[193],"CONCLUSIONS:":[194],"Hepatic":[195],"evident":[202],"underestimated.":[204],"provides":[208],"adequate":[210],"tool":[211],"determine":[213],"dysfunction.":[215],"Open":[216],"approaches":[219],"appeared":[220],"similar":[221],"terms":[223],"SIRS.":[229]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2017-08-31T00:00:00"}