{"id":"https://openalex.org/W2747005186","doi":"https://doi.org/10.15698/mic2017.09.589","title":"Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae","display_name":"Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae","publication_year":2017,"publication_date":"2017-08-30","ids":{"openalex":"https://openalex.org/W2747005186","doi":"https://doi.org/10.15698/mic2017.09.589","mag":"2747005186","pmid":"https://pubmed.ncbi.nlm.nih.gov/28913344","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5597792"},"language":"en","primary_location":{"id":"doi:10.15698/mic2017.09.589","doi":"https://doi.org/10.15698/mic2017.09.589","is_oa":true,"landing_page_url":"https://doi.org/10.15698/mic2017.09.589","pdf_url":"http://microbialcell.com/wordpress/wp-content/uploads/2017/09/2017A-Egbe-Microbial-Cell.pdf","source":{"id":"https://openalex.org/S2765077297","display_name":"Microbial Cell","issn_l":"2311-2638","issn":["2311-2638"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317901","host_organization_name":"Shared Science Publishers OG","host_organization_lineage":["https://openalex.org/P4310317901"],"host_organization_lineage_names":["Shared Science Publishers OG"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial Cell","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://microbialcell.com/wordpress/wp-content/uploads/2017/09/2017A-Egbe-Microbial-Cell.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023590027","display_name":"Nkechi Eucharia Egbe","orcid":"https://orcid.org/0000-0003-0086-2172","observed_orcids":["https://orcid.org/0000-0003-0086-2172"]},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I33783412","display_name":"Nigerian Defence Academy","ror":"https://ror.org/02nt7a109","country_code":"NG","type":"education","lineage":["https://openalex.org/I33783412"]}],"countries":["GB","NG"],"is_corresponding":false,"raw_author_name":"Nkechi E. Egbe","raw_affiliation_strings":["Current address: Department of Biological Sciences, Nigerian Defence Academy, PMB 2109, Kaduna, Nigeria","Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Current address: Department of Biological Sciences, Nigerian Defence Academy, PMB 2109, Kaduna, Nigeria","institution_ids":["https://openalex.org/I33783412"]},{"raw_affiliation_string":"Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005267708","display_name":"Tawni Dornelles","orcid":"https://orcid.org/0000-0003-4571-4982","observed_orcids":["https://orcid.org/0000-0003-4571-4982"]},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tawni O. Dornelles","raw_affiliation_strings":["Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108612891","display_name":"Caroline M. Paget","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Caroline M. Paget","raw_affiliation_strings":["Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017312818","display_name":"Lydia M. Castelli","orcid":"https://orcid.org/0000-0003-3620-4219","observed_orcids":["https://orcid.org/0000-0003-3620-4219"]},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I91136226","display_name":"University of Sheffield","ror":"https://ror.org/05krs5044","country_code":"GB","type":"education","lineage":["https://openalex.org/I91136226"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lydia M. Castelli","raw_affiliation_strings":["Current address: Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, S10 2HQ, United Kingdom","Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Current address: Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, S10 2HQ, United Kingdom","institution_ids":["https://openalex.org/I91136226"]},{"raw_affiliation_string":"Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071550154","display_name":"Mark Ashe","orcid":"https://orcid.org/0000-0002-4457-7851","observed_orcids":["https://orcid.org/0000-0002-4457-7851"]},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Mark P. Ashe","raw_affiliation_strings":["Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Michael Smith Building, Oxford Rd., Manchester, M13 9PT, United Kingdom","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5071550154"],"corresponding_institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"],"apc_list":{"value":1190,"currency":"EUR","value_usd":1283},"apc_paid":{"value":1231,"currency":"EUR","value_usd":1327},"fwci":1.1684,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.75534424,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"4","issue":"9","first_page":"294","last_page":"304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.15000000596046448,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/farnesol","display_name":"farnesol","score":1.0},{"id":"https://openalex.org/keywords/translation-initiation","display_name":"translation initiation","score":0.6200000047683716},{"id":"https://openalex.org/keywords/filamentous-growth","display_name":"filamentous growth","score":0.6060000061988831},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9670000076293945},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9950000047683716},{"id":"https://openalex.org/keywords/quorum-sensing","display_name":"quorum sensing","score":0.9309999942779541},{"id":"https://openalex.org/keywords/sesquiterpenes","display_name":"sesquiterpenes","score":0.8539999723434448},{"id":"https://openalex.org/keywords/higher-alcohols","display_name":"higher alcohols","score":0.9139999747276306},{"id":"https://openalex.org/keywords/eif2b","display_name":"eIF2B","score":0.9369999766349792},{"id":"https://openalex.org/keywords/small-ribosomal-subunit","display_name":"small ribosomal subunit","score":0.8949999809265137},{"id":"https://openalex.org/keywords/yeast-to-hypha-transition","display_name":"yeast-to-hypha transition","score":0.6340000033378601},{"id":"https://openalex.org/keywords/antifungal-agents","display_name":"antifungal agents","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C2779247237","wikidata":"https://www.wikidata.org/wiki/Q60194891","display_name":"Farnesol","level":2,"score":0.9732016324996948},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.7549793720245361},{"id":"https://openalex.org/C13984183","wikidata":"https://www.wikidata.org/wiki/Q751627","display_name":"Fusel alcohol","level":3,"score":0.5706650018692017},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.5664457678794861},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5592333674430847},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.4794672727584839},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.46633362770080566},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4562391936779022},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42126837372779846},{"id":"https://openalex.org/C118687296","wikidata":"https://www.wikidata.org/wiki/Q905754","display_name":"Quorum sensing","level":4,"score":0.4113464057445526},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.3997475802898407},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3865370750427246},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.37089651823043823},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.28226804733276367},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.26406413316726685},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0842122733592987},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.15698/mic2017.09.589","doi":"https://doi.org/10.15698/mic2017.09.589","is_oa":true,"landing_page_url":"https://doi.org/10.15698/mic2017.09.589","pdf_url":"http://microbialcell.com/wordpress/wp-content/uploads/2017/09/2017A-Egbe-Microbial-Cell.pdf","source":{"id":"https://openalex.org/S2765077297","display_name":"Microbial Cell","issn_l":"2311-2638","issn":["2311-2638"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317901","host_organization_name":"Shared Science Publishers OG","host_organization_lineage":["https://openalex.org/P4310317901"],"host_organization_lineage_names":["Shared Science Publishers OG"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial Cell","raw_type":"journal-article"},{"id":"pmid:28913344","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28913344","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial cell (Graz, Austria)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5597792","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5597792/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microb Cell","raw_type":"Text"},{"id":"pmh:oai:eprints.whiterose.ac.uk:123869","doi":null,"is_oa":false,"landing_page_url":"http://eprints.whiterose.ac.uk/123869/1/Farnesol%20inhibits%20translation%20to%20limit%20growth%20and%20filamentation%20in%20C.%20albicans%20and%20S.%20cerevisiae.pdf","pdf_url":"http://eprints.whiterose.ac.uk/123869/1/Farnesol%20inhibits%20translation%20to%20limit%20growth%20and%20filamentation%20in%20C.%20albicans%20and%20S.%20cerevisiae.pdf","source":{"id":"https://openalex.org/S4306400854","display_name":"White Rose Research Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:6b2a9f93a7e0418d908b4fee562a480b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6b2a9f93a7e0418d908b4fee562a480b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Microbial Cell, Vol 4, Iss 9, Pp 294-304 (2017)","raw_type":"article"},{"id":"pmh:oai:pure.atira.dk:openaire/7317c338-7052-499d-89ce-53825f58a535","doi":null,"is_oa":true,"landing_page_url":"https://research.manchester.ac.uk/en/publications/7317c338-7052-499d-89ce-53825f58a535","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Egbe, N, Dornelles, T, Paget, C, Castelli, L M & Ashe, M 2017, 'Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae', Microbial Cell, vol. 4, pp. 294-304. https://doi.org/10.15698/mic2017.09.589","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.15698/mic2017.09.589","doi":"https://doi.org/10.15698/mic2017.09.589","is_oa":true,"landing_page_url":"https://doi.org/10.15698/mic2017.09.589","pdf_url":"http://microbialcell.com/wordpress/wp-content/uploads/2017/09/2017A-Egbe-Microbial-Cell.pdf","source":{"id":"https://openalex.org/S2765077297","display_name":"Microbial Cell","issn_l":"2311-2638","issn":["2311-2638"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317901","host_organization_name":"Shared Science Publishers OG","host_organization_lineage":["https://openalex.org/P4310317901"],"host_organization_lineage_names":["Shared Science Publishers OG"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microbial Cell","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3259422429","display_name":"Synthetic approaches towards the production of biofuels from lignocellulosic feedstocks in yeast","funder_award_id":"BB/K002767/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4444663309","display_name":"Understanding how RNA interacting proteins modulate the translatability of mRNAs","funder_award_id":"BB/G012571/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2747005186.pdf","grobid_xml":"https://content.openalex.org/works/W2747005186.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W147851329","https://openalex.org/W302083790","https://openalex.org/W1820624545","https://openalex.org/W1968727721","https://openalex.org/W1970835750","https://openalex.org/W1972243502","https://openalex.org/W1983383814","https://openalex.org/W1985211845","https://openalex.org/W1988765006","https://openalex.org/W2002379595","https://openalex.org/W2008197488","https://openalex.org/W2012000892","https://openalex.org/W2015012952","https://openalex.org/W2016107719","https://openalex.org/W2027821655","https://openalex.org/W2031598460","https://openalex.org/W2054337320","https://openalex.org/W2059916510","https://openalex.org/W2067024190","https://openalex.org/W2075511135","https://openalex.org/W2076120836","https://openalex.org/W2080277707","https://openalex.org/W2083885449","https://openalex.org/W2091791993","https://openalex.org/W2098545768","https://openalex.org/W2100475145","https://openalex.org/W2100891288","https://openalex.org/W2102500167","https://openalex.org/W2102759838","https://openalex.org/W2103682285","https://openalex.org/W2108655462","https://openalex.org/W2109535551","https://openalex.org/W2112564055","https://openalex.org/W2114925097","https://openalex.org/W2115309695","https://openalex.org/W2119346976","https://openalex.org/W2123439193","https://openalex.org/W2131043780","https://openalex.org/W2131404785","https://openalex.org/W2132545724","https://openalex.org/W2134023413","https://openalex.org/W2134683677","https://openalex.org/W2135741099","https://openalex.org/W2136433399","https://openalex.org/W2139277896","https://openalex.org/W2140056398","https://openalex.org/W2140935709","https://openalex.org/W2141200742","https://openalex.org/W2144035662","https://openalex.org/W2144120004","https://openalex.org/W2144677145","https://openalex.org/W2145502099","https://openalex.org/W2145636884","https://openalex.org/W2158921674","https://openalex.org/W2160897547","https://openalex.org/W2163476908","https://openalex.org/W2165781451","https://openalex.org/W2166224554","https://openalex.org/W2168383988","https://openalex.org/W2170241476","https://openalex.org/W2171283475","https://openalex.org/W2520952968","https://openalex.org/W7074030849","https://openalex.org/W7100294453"],"related_works":["https://openalex.org/W1566137099","https://openalex.org/W7052954249","https://openalex.org/W2140056398","https://openalex.org/W4392378889","https://openalex.org/W1985211845","https://openalex.org/W2165459255","https://openalex.org/W4385406702","https://openalex.org/W2980967403","https://openalex.org/W2621610825","https://openalex.org/W2104825748"],"abstract_inverted_index":{"Candida":[0],"albicans":[1,54],"is":[2,16,20],"a":[3,21,97,109],"polymorphic":[4],"yeast":[5,12],"where":[6],"the":[7,48,64,72,75,78,87,101],"capacity":[8],"to":[9,59,83,107],"switch":[10],"between":[11],"and":[13,31,55],"filamentous":[14,35,116],"growth":[15,36],"critical":[17],"for":[18],"pathogenicity.Farnesol":[19],"quorum-sensing":[22],"sesquiterpene":[23],"alcohol":[24],"that,":[25],"via":[26],"regulation":[27],"of":[28,74,86],"specific":[29],"signalling":[30],"transcription":[32],"components,":[33],"inhibits":[34,45],"in":[37,51,92,100],"C.":[38,53],"albicans.Here":[39],"we":[40],"show":[41],"that":[42,62],"farnesol":[43,70,95],"also":[44],"translation":[46,102],"at":[47],"initiation":[49,66],"step":[50,99],"both":[52],"S.":[56,93],"cerevisiae.In":[57],"contrast":[58],"fusel":[60,105],"alcohols,":[61],"target":[63],"eukaryotic":[65],"factor":[67],"2B":[68],"(eIF2B),":[69],"affects":[71],"interaction":[73],"mRNA":[76],"with":[77],"small":[79],"ribosomal":[80,90],"subunit":[81],"leading":[82],"reduced":[84],"levels":[85],"48S":[88],"preinitiation":[89],"complex":[91],"cerevisiae.Therefore,":[94],"targets":[96],"different":[98],"pathway":[103],"than":[104],"alcohols":[106],"elicit":[108],"completely":[110],"opposite":[111],"physiological":[112],"outcome":[113],"by":[114],"negating":[115],"growth.":[117]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2017-08-31T00:00:00"}