{"id":"https://openalex.org/W2746089772","doi":"https://doi.org/10.1016/b978-0-12-801238-3.65734-3","title":"Developmental Immunotoxicology Testing (DIT)","display_name":"Developmental Immunotoxicology Testing (DIT)","publication_year":2017,"publication_date":"2017-08-17","ids":{"openalex":"https://openalex.org/W2746089772","doi":"https://doi.org/10.1016/b978-0-12-801238-3.65734-3","mag":"2746089772"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-801238-3.65734-3","doi":"https://doi.org/10.1016/b978-0-12-801238-3.65734-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-801238-3.65734-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Toxicology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4242887325","display_name":"Comprehensive Toxicology"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030047327","display_name":"Michael P. Holsapple","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Holsapple","raw_affiliation_strings":["Michigan State University, East Lansing, MI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University, East Lansing, MI, United States","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081183519","display_name":"Rodney A. Prell","orcid":"https://orcid.org/0000-0002-4762-2937","observed_orcids":["https://orcid.org/0000-0002-4762-2937"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. Prell","raw_affiliation_strings":["Safety Assessment, South San Francisco, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safety Assessment, South San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061386610","display_name":"Sarah S. Comstock","orcid":"https://orcid.org/0000-0003-3107-7652","observed_orcids":["https://orcid.org/0000-0003-3107-7652"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Comstock","raw_affiliation_strings":["Michigan State University, East Lansing, MI, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Michigan State University, East Lansing, MI, United States","institution_ids":["https://openalex.org/I87216513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5696,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.65084135,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"467","last_page":"497"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pregnancy-immunology","display_name":"pregnancy immunology","score":0.5460000038146973},{"id":"https://openalex.org/keywords/maternal-fetal-immune-tolerance","display_name":"maternal-fetal immune tolerance","score":0.8510000109672546},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.6949999928474426},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.9700000286102295},{"id":"https://openalex.org/keywords/immunosuppressive-drugs","display_name":"immunosuppressants","score":0.7960000038146973},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9710000157356262},{"id":"https://openalex.org/keywords/neonatal-immune-immaturity","display_name":"neonatal immune immaturity","score":0.8399999737739563},{"id":"https://openalex.org/keywords/neonatal-infection-susceptibility","display_name":"neonatal infection susceptibility","score":0.6809999942779541},{"id":"https://openalex.org/keywords/regulatory-toxicology","display_name":"regulatory toxicology","score":0.5580000281333923},{"id":"https://openalex.org/keywords/immune-system-development","display_name":"immune system development","score":0.4339999854564667}],"concepts":[{"id":"https://openalex.org/C159674089","wikidata":"https://www.wikidata.org/wiki/Q6005582","display_name":"Immunotoxicology","level":3,"score":0.9130189418792725},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7306389212608337},{"id":"https://openalex.org/C2778023277","wikidata":"https://www.wikidata.org/wiki/Q321703","display_name":"Premise","level":2,"score":0.5832394957542419},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.533073902130127},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4942484200000763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4311186671257019},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4222140312194824},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-801238-3.65734-3","doi":"https://doi.org/10.1016/b978-0-12-801238-3.65734-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-801238-3.65734-3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Toxicology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":300,"referenced_works":["https://openalex.org/W72596112","https://openalex.org/W121507408","https://openalex.org/W205568925","https://openalex.org/W244414928","https://openalex.org/W278701132","https://openalex.org/W427596666","https://openalex.org/W1431584087","https://openalex.org/W1499765142","https://openalex.org/W1523846987","https://openalex.org/W1524217669","https://openalex.org/W1529544531","https://openalex.org/W1535428241","https://openalex.org/W1536358893","https://openalex.org/W1557090560","https://openalex.org/W1565952974","https://openalex.org/W1578914995","https://openalex.org/W1580627905","https://openalex.org/W1582870359","https://openalex.org/W1588475303","https://openalex.org/W1636840105","https://openalex.org/W1642457845","https://openalex.org/W1647966696","https://openalex.org/W1790787093","https://openalex.org/W1815766538","https://openalex.org/W1819330710","https://openalex.org/W1929194486","https://openalex.org/W1931237845","https://openalex.org/W1941562583","https://openalex.org/W1942668068","https://openalex.org/W1963839080","https://openalex.org/W1964115194","https://openalex.org/W1964286278","https://openalex.org/W1964408684","https://openalex.org/W1964503014","https://openalex.org/W1967449698","https://openalex.org/W1967994686","https://openalex.org/W1968105193","https://openalex.org/W1968889897","https://openalex.org/W1969582479","https://openalex.org/W1970034838","https://openalex.org/W1970613924","https://openalex.org/W1970649642","https://openalex.org/W1970727168","https://openalex.org/W1970727996","https://openalex.org/W1975391560","https://openalex.org/W1977192877","https://openalex.org/W1977323242","https://openalex.org/W1978116307","https://openalex.org/W1978135030","https://openalex.org/W1980250352","https://openalex.org/W1982235189","https://openalex.org/W1982361212","https://openalex.org/W1983813529","https://openalex.org/W1984735358","https://openalex.org/W1984779201","https://openalex.org/W1984997549","https://openalex.org/W1985141199","https://openalex.org/W1985972532","https://openalex.org/W1987012470","https://openalex.org/W1989496524","https://openalex.org/W1990036222","https://openalex.org/W1990558523","https://openalex.org/W1992371996","https://openalex.org/W1993464662","https://openalex.org/W1993525891","https://openalex.org/W1993830991","https://openalex.org/W1994616457","https://openalex.org/W1994993231","https://openalex.org/W1995559307","https://openalex.org/W1996143244","https://openalex.org/W1996148181","https://openalex.org/W1996168096","https://openalex.org/W1998143514","https://openalex.org/W1999376421","https://openalex.org/W2000281244","https://openalex.org/W2001157494","https://openalex.org/W2001228876","https://openalex.org/W2001936082","https://openalex.org/W2001938165","https://openalex.org/W2002095044","https://openalex.org/W2003652884","https://openalex.org/W2004031864","https://openalex.org/W2004329990","https://openalex.org/W2004869330","https://openalex.org/W2005599815","https://openalex.org/W2006255159","https://openalex.org/W2007030576","https://openalex.org/W2007603900","https://openalex.org/W2008106611","https://openalex.org/W2008869982","https://openalex.org/W2011132772","https://openalex.org/W2011768190","https://openalex.org/W2012956083","https://openalex.org/W2013242597","https://openalex.org/W2013482710","https://openalex.org/W2013503010","https://openalex.org/W2015015427","https://openalex.org/W2015260577","https://openalex.org/W2015821770","https://openalex.org/W2017001902","https://openalex.org/W2018020394","https://openalex.org/W2018505426","https://openalex.org/W2018789682","https://openalex.org/W2021208119","https://openalex.org/W2022380356","https://openalex.org/W2023257193","https://openalex.org/W2023506796","https://openalex.org/W2023630186","https://openalex.org/W2024050678","https://openalex.org/W2024285987","https://openalex.org/W2025114863","https://openalex.org/W2026398217","https://openalex.org/W2026419325","https://openalex.org/W2028369131","https://openalex.org/W2028402779","https://openalex.org/W2029841107","https://openalex.org/W2030785705","https://openalex.org/W2031126484","https://openalex.org/W2031382003","https://openalex.org/W2031965453","https://openalex.org/W2032969373","https://openalex.org/W2034315313","https://openalex.org/W2035154598","https://openalex.org/W2035251786","https://openalex.org/W2036835958","https://openalex.org/W2038008301","https://openalex.org/W2038554653","https://openalex.org/W2039907390","https://openalex.org/W2041102049","https://openalex.org/W2043423615","https://openalex.org/W2044082121","https://openalex.org/W2044201812","https://openalex.org/W2044835625","https://openalex.org/W2045293532","https://openalex.org/W2048321060","https://openalex.org/W2048398316","https://openalex.org/W2048810850","https://openalex.org/W2048942183","https://openalex.org/W2051884331","https://openalex.org/W2052012061","https://openalex.org/W2052152612","https://openalex.org/W2052600727","https://openalex.org/W2052969143","https://openalex.org/W2054112179","https://openalex.org/W2055959752","https://openalex.org/W2059467769","https://openalex.org/W2059494963","https://openalex.org/W2060185417","https://openalex.org/W2061445575","https://openalex.org/W2064111999","https://openalex.org/W2067445465","https://openalex.org/W2069322489","https://openalex.org/W2071752880","https://openalex.org/W2072417345","https://openalex.org/W2072589585","https://openalex.org/W2072743252","https://openalex.org/W2073494022","https://openalex.org/W2075941008","https://openalex.org/W2076569607","https://openalex.org/W2076803046","https://openalex.org/W2077007054","https://openalex.org/W2077587895","https://openalex.org/W2080250524","https://openalex.org/W2080462324","https://openalex.org/W2080748790","https://openalex.org/W2081313422","https://openalex.org/W2084006363","https://openalex.org/W2085955756","https://openalex.org/W2086198494","https://openalex.org/W2086335340","https://openalex.org/W2086840459","https://openalex.org/W2087292184","https://openalex.org/W2087518307","https://openalex.org/W2087704409","https://openalex.org/W2089291803","https://openalex.org/W2089552931","https://openalex.org/W2090315260","https://openalex.org/W2091671016","https://openalex.org/W2092696502","https://openalex.org/W2093060517","https://openalex.org/W2093682373","https://openalex.org/W2094099911","https://openalex.org/W2094197484","https://openalex.org/W2095158284","https://openalex.org/W2095843734","https://openalex.org/W2095909640","https://openalex.org/W2096205027","https://openalex.org/W2098494951","https://openalex.org/W2098991824","https://openalex.org/W2099353457","https://openalex.org/W2099614922","https://openalex.org/W2099703022","https://openalex.org/W2099857099","https://openalex.org/W2100176567","https://openalex.org/W2100543326","https://openalex.org/W2103432593","https://openalex.org/W2103761010","https://openalex.org/W2104843179","https://openalex.org/W2107369528","https://openalex.org/W2107652077","https://openalex.org/W2108562508","https://openalex.org/W2108865848","https://openalex.org/W2109755334","https://openalex.org/W2110389012","https://openalex.org/W2111105005","https://openalex.org/W2111317067","https://openalex.org/W2111364385","https://openalex.org/W2112134219","https://openalex.org/W2112874908","https://openalex.org/W2115651087","https://openalex.org/W2117613892","https://openalex.org/W2118097954","https://openalex.org/W2122167931","https://openalex.org/W2122292170","https://openalex.org/W2122857656","https://openalex.org/W2122961446","https://openalex.org/W2124995875","https://openalex.org/W2125564014","https://openalex.org/W2126607132","https://openalex.org/W2127084866","https://openalex.org/W2128059561","https://openalex.org/W2128464247","https://openalex.org/W2129732696","https://openalex.org/W2129917444","https://openalex.org/W2131361374","https://openalex.org/W2133681569","https://openalex.org/W2134928825","https://openalex.org/W2135186145","https://openalex.org/W2136010542","https://openalex.org/W2136215278","https://openalex.org/W2137049163","https://openalex.org/W2137195441","https://openalex.org/W2139352881","https://openalex.org/W2139657682","https://openalex.org/W2139884694","https://openalex.org/W2140145798","https://openalex.org/W2142336938","https://openalex.org/W2142363681","https://openalex.org/W2142455012","https://openalex.org/W2142773418","https://openalex.org/W2143880475","https://openalex.org/W2144152742","https://openalex.org/W2144275312","https://openalex.org/W2144568881","https://openalex.org/W2146676630","https://openalex.org/W2148067809","https://openalex.org/W2149082787","https://openalex.org/W2149181253","https://openalex.org/W2149609143","https://openalex.org/W2151460235","https://openalex.org/W2153173272","https://openalex.org/W2153274950","https://openalex.org/W2155395286","https://openalex.org/W2155464214","https://openalex.org/W2155742883","https://openalex.org/W2155882037","https://openalex.org/W2156030157","https://openalex.org/W2156323383","https://openalex.org/W2158082105","https://openalex.org/W2158211840","https://openalex.org/W2158238031","https://openalex.org/W2159657989","https://openalex.org/W2161001701","https://openalex.org/W2161074777","https://openalex.org/W2161187897","https://openalex.org/W2161667744","https://openalex.org/W2162088497","https://openalex.org/W2162612026","https://openalex.org/W2163229571","https://openalex.org/W2163365895","https://openalex.org/W2163673280","https://openalex.org/W2163703413","https://openalex.org/W2163751839","https://openalex.org/W2165067288","https://openalex.org/W2165257283","https://openalex.org/W2166562121","https://openalex.org/W2166832786","https://openalex.org/W2167927725","https://openalex.org/W2168044782","https://openalex.org/W2168529398","https://openalex.org/W2170925079","https://openalex.org/W2171610361","https://openalex.org/W2178518272","https://openalex.org/W2187418127","https://openalex.org/W2188593832","https://openalex.org/W2199098011","https://openalex.org/W2218732210","https://openalex.org/W2266429966","https://openalex.org/W2296293854","https://openalex.org/W2329081999","https://openalex.org/W2340510729","https://openalex.org/W4211050189","https://openalex.org/W4231110705","https://openalex.org/W4233096244","https://openalex.org/W4238532985","https://openalex.org/W4240680252","https://openalex.org/W4240790019","https://openalex.org/W4247556390","https://openalex.org/W4254032310","https://openalex.org/W4313324525"],"related_works":["https://openalex.org/W162235549","https://openalex.org/W2139352881","https://openalex.org/W4230806509","https://openalex.org/W2132762401","https://openalex.org/W2129732696","https://openalex.org/W1596364128","https://openalex.org/W7161007499","https://openalex.org/W1993464662","https://openalex.org/W2158238031","https://openalex.org/W2002095044"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-08-31T00:00:00"}
