{"id":"https://openalex.org/W2744898508","doi":"https://doi.org/10.1016/j.tibtech.2017.07.006","title":"Bioprinting and Cellular Therapies for Type 1 Diabetes","display_name":"Bioprinting and Cellular Therapies for Type 1 Diabetes","publication_year":2017,"publication_date":"2017-08-05","ids":{"openalex":"https://openalex.org/W2744898508","doi":"https://doi.org/10.1016/j.tibtech.2017.07.006","mag":"2744898508","pmid":"https://pubmed.ncbi.nlm.nih.gov/28789815"},"language":"en","primary_location":{"id":"doi:10.1016/j.tibtech.2017.07.006","doi":"https://doi.org/10.1016/j.tibtech.2017.07.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tibtech.2017.07.006","pdf_url":null,"source":{"id":"https://openalex.org/S147849156","display_name":"Trends in biotechnology","issn_l":"0167-7799","issn":["0167-7799","0167-9430","1879-3096"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Biotechnology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056618662","display_name":"Dino J. Ravnic","orcid":"https://orcid.org/0000-0003-2261-5180","observed_orcids":["https://orcid.org/0000-0003-2261-5180"]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dino J. Ravnic","raw_affiliation_strings":["Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035651531","display_name":"Ashley N. Leberfinger","orcid":"https://orcid.org/0000-0002-8688-8789","observed_orcids":["https://orcid.org/0000-0002-8688-8789"]},"institutions":[{"id":"https://openalex.org/I82783531","display_name":"Penn State Milton S. Hershey Medical Center","ror":"https://ror.org/01h22ap11","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I82783531"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley N. Leberfinger","raw_affiliation_strings":["Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA","institution_ids":["https://openalex.org/I82783531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083046197","display_name":"Ibrahim Tarik Ozbolat","orcid":"https://orcid.org/0000-0001-8328-4528","observed_orcids":["https://orcid.org/0000-0001-8328-4528"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ibrahim T. Ozbolat","raw_affiliation_strings":["Department of Engineering Science and Mechanics, Penn State University, University Park, PA, USA; Department of Biomedical Engineering, Penn State University, University Park, PA, USA; Huck Institutes of the Life Sciences, Penn State University, University Park, PA, USA; Materials Research Institute, Penn State University, University Park, PA, USA. Electronic address: ito1@psu.edu","Department of Biomedical Engineering, Penn State University, University Park, PA, USA","Department of Engineering Science and Mechanics, Penn State University, University Park, PA, USA","Huck Institutes of the Life Sciences, Penn State University, University Park, PA, USA","Materials Research Institute, Penn State University, University Park, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Engineering Science and Mechanics, Penn State University, University Park, PA, USA; Department of Biomedical Engineering, Penn State University, University Park, PA, USA; Huck Institutes of the Life Sciences, Penn State University, University Park, PA, USA; Materials Research Institute, Penn State University, University Park, PA, USA. Electronic address: ito1@psu.edu","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Department of Engineering Science and Mechanics, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Huck Institutes of the Life Sciences, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Materials Research Institute, Penn State University, University Park, PA, USA","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5083046197"],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":{"value":7030,"currency":"USD","value_usd":7030},"apc_paid":null,"fwci":1.2641,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.76371173,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"35","issue":"11","first_page":"1025","last_page":"1034"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.7275000214576721,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.7275000214576721,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.26829999685287476,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9940000176429749},{"id":"https://openalex.org/keywords/bioprinting","display_name":"bioprinting","score":0.9200000166893005},{"id":"https://openalex.org/keywords/beta-cell-replacement","display_name":"beta cell replacement","score":0.746999979019165},{"id":"https://openalex.org/keywords/pancreatic-islets","display_name":"pancreatic islets","score":0.8029999732971191},{"id":"https://openalex.org/keywords/stem-cell-derived-beta-cells","display_name":"stem cell-derived beta cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/pancreatic-tissue-engineering","display_name":"pancreatic tissue engineering","score":0.6949999928474426},{"id":"https://openalex.org/keywords/vascularization","display_name":"vascularization","score":0.8769999742507935},{"id":"https://openalex.org/keywords/encapsulation","display_name":"encapsulation","score":0.9010000228881836},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.7570734024047852},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5374425649642944},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.5255179405212402},{"id":"https://openalex.org/C2779718196","wikidata":"https://www.wikidata.org/wiki/Q17018741","display_name":"3D bioprinting","level":3,"score":0.5177797079086304},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.48967626690864563},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4668603241443634},{"id":"https://openalex.org/C2779855799","wikidata":"https://www.wikidata.org/wiki/Q728309","display_name":"Pancreatic islets","level":4,"score":0.45228075981140137},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.4510688781738281},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4406401515007019},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.41382667422294617},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.39757952094078064},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3665589690208435},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35700756311416626},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3515506386756897},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.30317223072052},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2617930769920349},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.2309536635875702},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.22703304886817932},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.09942430257797241},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019397","descriptor_name":"Pancreas, Artificial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D050417","descriptor_name":"Insulin-Secreting Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D064987","descriptor_name":"Cell- and Tissue-Based Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.tibtech.2017.07.006","doi":"https://doi.org/10.1016/j.tibtech.2017.07.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tibtech.2017.07.006","pdf_url":null,"source":{"id":"https://openalex.org/S147849156","display_name":"Trends in biotechnology","issn_l":"0167-7799","issn":["0167-7799","0167-9430","1879-3096"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Biotechnology","raw_type":"journal-article"},{"id":"pmid:28789815","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28789815","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in biotechnology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W10900175","https://openalex.org/W1549442982","https://openalex.org/W1592686897","https://openalex.org/W1739944755","https://openalex.org/W1859700011","https://openalex.org/W1881445774","https://openalex.org/W1964123012","https://openalex.org/W1964925945","https://openalex.org/W1973424799","https://openalex.org/W1999202962","https://openalex.org/W2000587835","https://openalex.org/W2005817636","https://openalex.org/W2018642982","https://openalex.org/W2019136342","https://openalex.org/W2045388234","https://openalex.org/W2045852090","https://openalex.org/W2048345383","https://openalex.org/W2048644480","https://openalex.org/W2050940851","https://openalex.org/W2054995347","https://openalex.org/W2075048575","https://openalex.org/W2082176642","https://openalex.org/W2109601009","https://openalex.org/W2117657337","https://openalex.org/W2128265130","https://openalex.org/W2129322399","https://openalex.org/W2130119039","https://openalex.org/W2148890861","https://openalex.org/W2203385592","https://openalex.org/W2238921013","https://openalex.org/W2255517791","https://openalex.org/W2260094956","https://openalex.org/W2265806176","https://openalex.org/W2295454854","https://openalex.org/W2330039704","https://openalex.org/W2334288083","https://openalex.org/W2336446961","https://openalex.org/W2381312419","https://openalex.org/W2411101077","https://openalex.org/W2474901368","https://openalex.org/W2502401296","https://openalex.org/W2521850524","https://openalex.org/W2528857504","https://openalex.org/W2536784027","https://openalex.org/W2552343274","https://openalex.org/W2557323065","https://openalex.org/W2562591732","https://openalex.org/W2568275076","https://openalex.org/W2577215016","https://openalex.org/W2579544621","https://openalex.org/W2591006736","https://openalex.org/W2592059614","https://openalex.org/W2604852286","https://openalex.org/W2605392052","https://openalex.org/W2605738255","https://openalex.org/W2606611764","https://openalex.org/W2613641503","https://openalex.org/W2736029153"],"related_works":["https://openalex.org/W4382133685","https://openalex.org/W4317425958","https://openalex.org/W4389420751","https://openalex.org/W2117864832","https://openalex.org/W3174322645","https://openalex.org/W2954675008","https://openalex.org/W2747394543","https://openalex.org/W3185481711","https://openalex.org/W1976911329","https://openalex.org/W7055591224"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-08-17T00:00:00"}