{"id":"https://openalex.org/W2743689049","doi":"https://doi.org/10.1016/j.bcmd.2017.08.010","title":"The pressing need for point-of-care diagnostics for sickle cell disease: A review of current and future technologies","display_name":"The pressing need for point-of-care diagnostics for sickle cell disease: A review of current and future technologies","publication_year":2017,"publication_date":"2017-08-08","ids":{"openalex":"https://openalex.org/W2743689049","doi":"https://doi.org/10.1016/j.bcmd.2017.08.010","mag":"2743689049","pmid":"https://pubmed.ncbi.nlm.nih.gov/28844459","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5868350"},"language":"en","primary_location":{"id":"doi:10.1016/j.bcmd.2017.08.010","doi":"https://doi.org/10.1016/j.bcmd.2017.08.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bcmd.2017.08.010","pdf_url":null,"source":{"id":"https://openalex.org/S183588319","display_name":"Blood Cells Molecules and Diseases","issn_l":"1079-9796","issn":["1079-9796","1096-0961"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cells, Molecules, and Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5868350","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017286562","display_name":"Patrick T. McGann","orcid":"https://orcid.org/0000-0001-6198-4785","observed_orcids":["https://orcid.org/0000-0001-6198-4785"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Patrick T. McGann","raw_affiliation_strings":["Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Electronic address: patrick.mcgann@cchmc.org","Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. Electronic address: patrick.mcgann@cchmc.org","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001812366","display_name":"Carolyn C. Hoppe","orcid":"https://orcid.org/0000-0001-9213-0547","observed_orcids":["https://orcid.org/0000-0001-9213-0547"]},"institutions":[{"id":"https://openalex.org/I4210135903","display_name":"UCSF Benioff Children's Hospital","ror":"https://ror.org/03hwe2705","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210135903"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carolyn Hoppe","raw_affiliation_strings":["UCSF Benioff Children's Hospital Oakland, Oakland, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCSF Benioff Children's Hospital Oakland, Oakland, CA, USA","institution_ids":["https://openalex.org/I4210135903"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5017286562"],"corresponding_institution_ids":["https://openalex.org/I1285204247"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":2.9676,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.91900106,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"67","issue":null,"first_page":"104","last_page":"113"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/point-of-care-testing","display_name":"point-of-care testing","score":0.9789999723434448},{"id":"https://openalex.org/keywords/resource-limited-settings","display_name":"resource-limited settings","score":0.7689999938011169},{"id":"https://openalex.org/keywords/sub-saharan-africa","display_name":"sub-Saharan Africa","score":0.8889999985694885},{"id":"https://openalex.org/keywords/diagnostic-capacity","display_name":"diagnostic capacity","score":0.4950000047683716},{"id":"https://openalex.org/keywords/newborn-screening","display_name":"newborn screening","score":0.4410000145435333}],"concepts":[{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.6565268635749817},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6528961062431335},{"id":"https://openalex.org/C64841741","wikidata":"https://www.wikidata.org/wiki/Q491983","display_name":"Point-of-care testing","level":2,"score":0.5948647856712341},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5771746635437012},{"id":"https://openalex.org/C3019252630","wikidata":"https://www.wikidata.org/wiki/Q6549547","display_name":"Limited resources","level":2,"score":0.48858460783958435},{"id":"https://openalex.org/C82157600","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic test","level":2,"score":0.4803779721260071},{"id":"https://openalex.org/C2776169613","wikidata":"https://www.wikidata.org/wiki/Q2305910","display_name":"Newborn screening","level":2,"score":0.4337945580482483},{"id":"https://openalex.org/C51915194","wikidata":"https://www.wikidata.org/wiki/Q17075487","display_name":"Point of care","level":2,"score":0.41954994201660156},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.31851208209991455},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.29348379373550415},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.199314683675766}],"mesh":[{"descriptor_ui":"D000068997","descriptor_name":"Smartphone","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D000068997","descriptor_name":"Smartphone","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000755","descriptor_name":"Anemia, Sickle Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D007118","descriptor_name":"Immunoassay","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D014943","descriptor_name":"Global Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019095","descriptor_name":"Point-of-Care Systems","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D046209","descriptor_name":"Electrophoresis, Microchip","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D046209","descriptor_name":"Electrophoresis, Microchip","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D046209","descriptor_name":"Electrophoresis, Microchip","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.bcmd.2017.08.010","doi":"https://doi.org/10.1016/j.bcmd.2017.08.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bcmd.2017.08.010","pdf_url":null,"source":{"id":"https://openalex.org/S183588319","display_name":"Blood Cells Molecules and Diseases","issn_l":"1079-9796","issn":["1079-9796","1096-0961"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Cells, Molecules, and Diseases","raw_type":"journal-article"},{"id":"pmid:28844459","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28844459","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood cells, molecules & diseases","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:5070071","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5868350","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5868350","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5868350","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Blood Cells Mol Dis","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5070071","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5868350","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2567098616","display_name":"Therapeutic Response Evaluation and Adherence Trial: A Prospective Study of Hydroxyurea for Children with Sickle Cell Anemia","funder_award_id":"K23HL128885","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4004785396","display_name":null,"funder_award_id":"L40 HL124407","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1561942429","https://openalex.org/W1763433851","https://openalex.org/W1783508625","https://openalex.org/W1916564595","https://openalex.org/W1924733452","https://openalex.org/W1977977041","https://openalex.org/W1986202585","https://openalex.org/W1990121208","https://openalex.org/W2016579685","https://openalex.org/W2020147687","https://openalex.org/W2023425238","https://openalex.org/W2031721952","https://openalex.org/W2056183152","https://openalex.org/W2078729510","https://openalex.org/W2084340774","https://openalex.org/W2084620919","https://openalex.org/W2098388627","https://openalex.org/W2112295445","https://openalex.org/W2112587241","https://openalex.org/W2115657655","https://openalex.org/W2119188897","https://openalex.org/W2125290890","https://openalex.org/W2138719823","https://openalex.org/W2139823675","https://openalex.org/W2140041909","https://openalex.org/W2141187979","https://openalex.org/W2161448604","https://openalex.org/W2167261134","https://openalex.org/W2167851873","https://openalex.org/W2170750555","https://openalex.org/W2177045159","https://openalex.org/W2226144245","https://openalex.org/W2470326011","https://openalex.org/W2478583935","https://openalex.org/W2510565279","https://openalex.org/W2543380750","https://openalex.org/W3093510056","https://openalex.org/W3153689256","https://openalex.org/W4292341608","https://openalex.org/W4400718689"],"related_works":["https://openalex.org/W2983013768","https://openalex.org/W2552707922","https://openalex.org/W3187640598","https://openalex.org/W2586360800","https://openalex.org/W4417016108","https://openalex.org/W1920731292","https://openalex.org/W7095715346","https://openalex.org/W2078628426","https://openalex.org/W2161448604","https://openalex.org/W2895436157"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2017-08-17T00:00:00"}