{"id":"https://openalex.org/W2741241374","doi":"https://doi.org/10.1039/c7nr03809g","title":"A DNA bipedal nanowalker with a piston-like expulsion stroke","display_name":"A DNA bipedal nanowalker with a piston-like expulsion stroke","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2741241374","doi":"https://doi.org/10.1039/c7nr03809g","mag":"2741241374","pmid":"https://pubmed.ncbi.nlm.nih.gov/28805877"},"language":"en","primary_location":{"id":"doi:10.1039/c7nr03809g","doi":"https://doi.org/10.1039/c7nr03809g","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c7nr03809g","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2017/nr/c7nr03809g","source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://pubs.rsc.org/en/content/articlepdf/2017/nr/c7nr03809g","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042739231","display_name":"Q. Y. Yeo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Q. Y. Yeo","raw_affiliation_strings":["Department of Physics","National University of Singapore","Singapore 117542","Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]},{"raw_affiliation_string":"Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015080612","display_name":"Iong Ying Loh","orcid":"https://orcid.org/0000-0003-3202-6961","observed_orcids":["https://orcid.org/0000-0003-3202-6961"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"I. Y. Loh","raw_affiliation_strings":["Department of Physics","National University of Singapore","Singapore 117542","Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]},{"raw_affiliation_string":"Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025188127","display_name":"Shern R. Tee","orcid":"https://orcid.org/0000-0003-2701-005X","observed_orcids":["https://orcid.org/0000-0003-2701-005X"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"S. R. Tee","raw_affiliation_strings":["Department of Physics","National University of Singapore","Singapore 117542"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057576950","display_name":"Y. H. Chiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Y. H. Chiang","raw_affiliation_strings":["Department of Physics","National University of Singapore","Singapore 117542","Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]},{"raw_affiliation_string":"Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011370312","display_name":"Juan Cheng","orcid":"https://orcid.org/0000-0002-1530-8118","observed_orcids":["https://orcid.org/0000-0002-1530-8118"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"J. Cheng","raw_affiliation_strings":["Department of Physics","National University of Singapore","Singapore 117542","Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]},{"raw_affiliation_string":"Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037522379","display_name":"M. H. Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"M. H. Liu","raw_affiliation_strings":["Department of Physics","National University of Singapore","Singapore 117542","Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]},{"raw_affiliation_string":"Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087700327","display_name":"Zhisong Wang","orcid":"https://orcid.org/0000-0001-5707-5909","observed_orcids":["https://orcid.org/0000-0001-5707-5909"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Z. S. Wang","raw_affiliation_strings":["Department of Physics","NUS Graduate School of Integrative Sciences and Engineering","National University of Singapore","Singapore 117542","Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","NUS Graduate School of Integrative Sciences and Engineering, National University of Singapore, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-5707-5909","affiliations":[{"raw_affiliation_string":"Department of Physics","institution_ids":[]},{"raw_affiliation_string":"NUS Graduate School of Integrative Sciences and Engineering","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"National University of Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Singapore 117542","institution_ids":[]},{"raw_affiliation_string":"Department of Physics, National University of Singapore, 2 Science Drive 3, Singapore 117542","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"NUS Graduate School of Integrative Sciences and Engineering, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5087700327"],"corresponding_institution_ids":["https://openalex.org/I165932596"],"apc_list":null,"apc_paid":null,"fwci":1.9483,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.8666425,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"9","issue":"33","first_page":"12142","last_page":"12149"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10578","display_name":"Supramolecular Chemistry and Complexes","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11486","display_name":"Micro and Nano Robotics","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/3104","display_name":"Condensed Matter Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-molecular-machines","display_name":"artificial molecular machines","score":0.7049999833106995},{"id":"https://openalex.org/keywords/dna-nanotechnology","display_name":"DNA nanotechnology","score":0.39899998903274536}],"concepts":[{"id":"https://openalex.org/C152279782","wikidata":"https://www.wikidata.org/wiki/Q13583542","display_name":"Shearing (physics)","level":2,"score":0.5537803173065186},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46600279211997986},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4238432049751282},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.42363452911376953},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3740023970603943},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32158714532852173},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21903899312019348},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1703002154827118},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.10210800170898438},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1039/c7nr03809g","doi":"https://doi.org/10.1039/c7nr03809g","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c7nr03809g","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2017/nr/c7nr03809g","source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},{"id":"pmid:28805877","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28805877","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"Journal Article"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/174418","doi":null,"is_oa":false,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/174418","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Unpaywall 20200831","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1039/c7nr03809g","doi":"https://doi.org/10.1039/c7nr03809g","is_oa":true,"landing_page_url":"https://doi.org/10.1039/c7nr03809g","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2017/nr/c7nr03809g","source":{"id":"https://openalex.org/S23181512","display_name":"Nanoscale","issn_l":"2040-3364","issn":["2040-3364","2040-3372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanoscale","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2741241374.pdf","grobid_xml":"https://content.openalex.org/works/W2741241374.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1970574292","https://openalex.org/W1988749907","https://openalex.org/W1991889118","https://openalex.org/W1993177346","https://openalex.org/W1993933078","https://openalex.org/W1997773664","https://openalex.org/W2005025782","https://openalex.org/W2005637794","https://openalex.org/W2006219289","https://openalex.org/W2007374102","https://openalex.org/W2026285337","https://openalex.org/W2032813700","https://openalex.org/W2034300905","https://openalex.org/W2034748091","https://openalex.org/W2040566267","https://openalex.org/W2059985845","https://openalex.org/W2071397131","https://openalex.org/W2084798466","https://openalex.org/W2087518856","https://openalex.org/W2105669930","https://openalex.org/W2126047677","https://openalex.org/W2127991158","https://openalex.org/W2131740634","https://openalex.org/W2144506694","https://openalex.org/W2153700418","https://openalex.org/W2157539087","https://openalex.org/W2164215798","https://openalex.org/W2170311889","https://openalex.org/W2317330415","https://openalex.org/W2334253417","https://openalex.org/W2442177838","https://openalex.org/W2588932275","https://openalex.org/W4211203651","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2802784346","https://openalex.org/W2938809259","https://openalex.org/W4234742098","https://openalex.org/W2087518856","https://openalex.org/W2334253417","https://openalex.org/W2802647167","https://openalex.org/W3039550996","https://openalex.org/W2790971206","https://openalex.org/W2546915281","https://openalex.org/W4364351849"],"abstract_inverted_index":{"Artificial":[0],"molecular":[1],"walkers":[2,101,116,157],"beyond":[3],"burn-bridge":[4],"designs":[5],"are":[6],"important":[7],"for":[8,36,126,144,154],"nanotechnology,":[9],"but":[10,130],"their":[11],"systematic":[12],"development":[13],"remains":[14],"difficult.":[15],"Herein,":[16],"we":[17],"have":[18],"reported":[19,136],"a":[20,30,57,78,89,119],"new":[21],"rationally":[22],"designed":[23],"DNA":[24,41,149],"walker-track":[25],"system":[26],"and":[27,52,67,117],"experimentally":[28],"verified":[29],"previously":[31,135],"proposed":[32],"general":[33],"expulsion":[34,80,87],"regime":[35],"implementing":[37],"non-burn-bridge":[38],"nanowalkers.":[39,146],"The":[40,61,82,147],"walker":[42,55],"has":[43],"an":[44,65],"optically":[45],"powered":[46],"engine":[47],"motif":[48],"that":[49,123],"reversibly":[50],"extends":[51],"contracts":[53],"the":[54,72,86,93,96,162],"via":[56],"quadruplex-duplex":[58],"conformational":[59],"change.":[60],"walker's":[62,73],"extension":[63],"is":[64,151,165],"energy-absorbing":[66],"force-generating":[68],"process,":[69],"which":[70,91],"drives":[71],"leg":[74],"dissociation":[75],"off-track":[76],"in":[77,134],"piston-like":[79],"stroke.":[81],"unzipping-shearing":[83,163],"asymmetry":[84,164],"provides":[85],"stroke":[88],"bias,":[90],"decides":[92],"direction":[94],"of":[95,102,112],"walker.":[97],"Moreover,":[98],"three":[99],"candidate":[100],"different":[103],"sizes":[104],"were":[105],"fabricated.":[106],"Fluorescence":[107],"motility":[108],"experiments":[109],"indicated":[110],"two":[111],"them":[113],"as":[114],"successful":[115],"revealed":[118],"distinctive":[120],"size":[121],"dependence":[122],"was":[124,131],"expected":[125],"these":[127],"expulsive":[128,145],"walkers,":[129],"not":[132],"observed":[133],"walkers.":[137],"This":[138],"study":[139],"identifies":[140],"unique":[141],"technical":[142],"requirements":[143],"present":[148],"design":[150],"readily":[152],"adapted":[153],"making":[155],"similar":[156],"from":[158],"other":[159],"molecules":[160],"since":[161],"common.":[166]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2017-08-08T00:00:00"}