{"id":"https://openalex.org/W2740976277","doi":"https://doi.org/10.1186/s13195-017-0278-2","title":"Behavioural and neuroanatomical correlates of auditory speech analysis in primary progressive aphasias","display_name":"Behavioural and neuroanatomical correlates of auditory speech analysis in primary progressive aphasias","publication_year":2017,"publication_date":"2017-07-27","ids":{"openalex":"https://openalex.org/W2740976277","doi":"https://doi.org/10.1186/s13195-017-0278-2","mag":"2740976277","pmid":"https://pubmed.ncbi.nlm.nih.gov/28750682","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5531024"},"language":"en","primary_location":{"id":"doi:10.1186/s13195-017-0278-2","doi":"https://doi.org/10.1186/s13195-017-0278-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13195-017-0278-2","pdf_url":"https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-017-0278-2","source":{"id":"https://openalex.org/S140755874","display_name":"Alzheimer s Research & Therapy","issn_l":"1758-9193","issn":["1758-9193"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's Research & Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-017-0278-2","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069154996","display_name":"Chris J. D. Hardy","orcid":"https://orcid.org/0000-0002-4900-6492","observed_orcids":["https://orcid.org/0000-0002-4900-6492"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Chris J. D. Hardy","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022249548","display_name":"Jennifer L. Agustus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jennifer L. Agustus","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081470647","display_name":"Charles R. Marshall","orcid":"https://orcid.org/0000-0002-8227-2354","observed_orcids":["https://orcid.org/0000-0002-8227-2354"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Charles R. Marshall","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062961621","display_name":"Camilla Neergaard Clark","orcid":"https://orcid.org/0000-0002-2817-2352","observed_orcids":["https://orcid.org/0000-0002-2817-2352"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Camilla N. Clark","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068882196","display_name":"Lucy Louise Russell","orcid":"https://orcid.org/0000-0001-5023-5893","observed_orcids":["https://orcid.org/0000-0001-5023-5893"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lucy L. Russell","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071820037","display_name":"Rebecca L. Bond","orcid":"https://orcid.org/0000-0001-7724-3789","observed_orcids":["https://orcid.org/0000-0001-7724-3789"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rebecca L. Bond","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062482628","display_name":"Emilie Brotherhood","orcid":"https://orcid.org/0000-0002-6244-7735","observed_orcids":["https://orcid.org/0000-0002-6244-7735"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Emilie V. Brotherhood","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087017337","display_name":"David Lee Thomas","orcid":"https://orcid.org/0000-0003-1491-1641","observed_orcids":["https://orcid.org/0000-0003-1491-1641"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David L. Thomas","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037524623","display_name":"Sebastian James Crutch","orcid":"https://orcid.org/0000-0002-4160-0139","observed_orcids":["https://orcid.org/0000-0002-4160-0139"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sebastian J. Crutch","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070348432","display_name":"Jonathan Daniel Rohrer","orcid":"https://orcid.org/0000-0002-6155-8417","observed_orcids":["https://orcid.org/0000-0002-6155-8417"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jonathan D. Rohrer","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068675261","display_name":"Jason D. Warren","orcid":"https://orcid.org/0000-0002-5405-0826","observed_orcids":["https://orcid.org/0000-0002-5405-0826"]},"institutions":[{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jason D. Warren","raw_affiliation_strings":["Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK. jason.warren@ucl.ac.uk","Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK. jason.warren@ucl.ac.uk","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068675261"],"corresponding_institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"],"apc_list":{"value":4290,"currency":"USD","value_usd":4290},"apc_paid":{"value":1593,"currency":"EUR","value_usd":1718},"fwci":1.3754,"has_fulltext":true,"cited_by_count":34,"citation_normalized_percentile":{"value":0.78719299,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"53","last_page":"53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10465","display_name":"Neurobiology of Language and Bilingualism","score":0.5708000063896179,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10465","display_name":"Neurobiology of Language and Bilingualism","score":0.5708000063896179,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.40720000863075256,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-progressive-aphasia","display_name":"primary progressive aphasia","score":0.902999997138977},{"id":"https://openalex.org/keywords/non-fluent-variant-ppa","display_name":"non-fluent variant PPA","score":0.953000009059906},{"id":"https://openalex.org/keywords/semantic-variant-ppa","display_name":"semantic variant PPA","score":1.0},{"id":"https://openalex.org/keywords/auditory-speech-processing","display_name":"auditory speech processing","score":0.9100000262260437},{"id":"https://openalex.org/keywords/temporal-regularity","display_name":"temporal regularity","score":0.8899999856948853},{"id":"https://openalex.org/keywords/supplementary-motor-area","display_name":"supplementary motor area","score":0.824999988079071},{"id":"https://openalex.org/keywords/caudate-nucleus","display_name":"caudate nucleus","score":0.9679999947547913},{"id":"https://openalex.org/keywords/supramarginal-gyrus","display_name":"supramarginal gyrus","score":0.9760000109672546},{"id":"https://openalex.org/keywords/putamen","display_name":"putamen","score":0.9959999918937683},{"id":"https://openalex.org/keywords/grey-matter","display_name":"grey matter","score":0.8019999861717224},{"id":"https://openalex.org/keywords/neuroanatomical-substrates","display_name":"neuroanatomical substrates","score":0.5849999785423279},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.6669999957084656},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7850000262260437}],"concepts":[{"id":"https://openalex.org/C2779140760","wikidata":"https://www.wikidata.org/wiki/Q18767","display_name":"Primary progressive aphasia","level":5,"score":0.6240035891532898},{"id":"https://openalex.org/C2778013878","wikidata":"https://www.wikidata.org/wiki/Q646150","display_name":"Grey matter","level":4,"score":0.533656895160675},{"id":"https://openalex.org/C2776793567","wikidata":"https://www.wikidata.org/wiki/Q1528202","display_name":"Supramarginal gyrus","level":3,"score":0.5149407982826233},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.5019855499267578},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.44180235266685486},{"id":"https://openalex.org/C200134340","wikidata":"https://www.wikidata.org/wiki/Q845664","display_name":"Voxel-based morphometry","level":4,"score":0.43216636776924133},{"id":"https://openalex.org/C61328038","wikidata":"https://www.wikidata.org/wiki/Q3358061","display_name":"Speech processing","level":2,"score":0.42248091101646423},{"id":"https://openalex.org/C197640229","wikidata":"https://www.wikidata.org/wiki/Q2534066","display_name":"Predictability","level":2,"score":0.41538625955581665},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.35026663541793823},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3390434980392456},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.33482688665390015},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.26872360706329346},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.26150861382484436},{"id":"https://openalex.org/C28490314","wikidata":"https://www.wikidata.org/wiki/Q189436","display_name":"Speech recognition","level":1,"score":0.2536121606826782},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2157364785671234},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.20551392436027527},{"id":"https://openalex.org/C2778641062","wikidata":"https://www.wikidata.org/wiki/Q18592","display_name":"Frontotemporal dementia","level":4,"score":0.19072934985160828},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.15956568717956543},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.14699503779411316},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.11264011263847351},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000161","descriptor_name":"Acoustic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008609","descriptor_name":"Mental Status Schedule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011571","descriptor_name":"Psychoacoustics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013060","descriptor_name":"Speech","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018888","descriptor_name":"Aphasia, Primary Progressive","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D018888","descriptor_name":"Aphasia, Primary Progressive","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D018888","descriptor_name":"Aphasia, Primary Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018888","descriptor_name":"Aphasia, Primary Progressive","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1186/s13195-017-0278-2","doi":"https://doi.org/10.1186/s13195-017-0278-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13195-017-0278-2","pdf_url":"https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-017-0278-2","source":{"id":"https://openalex.org/S140755874","display_name":"Alzheimer s Research & Therapy","issn_l":"1758-9193","issn":["1758-9193"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's Research & Therapy","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5531024","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5531024","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimers Res Ther","raw_type":"Text"},{"id":"pmid:28750682","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28750682","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's research & therapy","raw_type":"Journal Article"},{"id":"pmh:oai:openaccess.sgul.ac.uk:112256","doi":null,"is_oa":false,"landing_page_url":"http://openaccess.sgul.ac.uk/112256/1/Hardy_Warren_behav_neuroanato_Alz_res_therapy_2017.pdf","pdf_url":"http://openaccess.sgul.ac.uk/112256/1/Hardy_Warren_behav_neuroanato_Alz_res_therapy_2017.pdf","source":{"id":"https://openalex.org/S4306400552","display_name":"St George's Online Research Archive (St George's University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I165862685","host_organization_name":"St George's, University of London","host_organization_lineage":["https://openalex.org/I165862685"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:330088e3d5074a669c1e7fb5c727e7ce","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/330088e3d5074a669c1e7fb5c727e7ce","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Alzheimer\u2019s Research & Therapy, Vol 9, Iss 1, Pp 1-10 (2017)","raw_type":"article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1567954","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1567954/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Alzheimer's Research & Therapy , 9 , Article 53. (2017)","raw_type":"Article"},{"id":"pmh:oai:qmro.qmul.ac.uk:123456789/46088","doi":null,"is_oa":true,"landing_page_url":"http://qmro.qmul.ac.uk/xmlui/handle/123456789/46088","pdf_url":null,"source":{"id":"https://openalex.org/S4306400530","display_name":"Queen Mary Research Online (Queen Mary University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I166337079","host_organization_name":"Queen Mary University of London","host_organization_lineage":["https://openalex.org/I166337079"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/s13195-017-0278-2","doi":"https://doi.org/10.1186/s13195-017-0278-2","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13195-017-0278-2","pdf_url":"https://alzres.biomedcentral.com/counter/pdf/10.1186/s13195-017-0278-2","source":{"id":"https://openalex.org/S140755874","display_name":"Alzheimer s Research & Therapy","issn_l":"1758-9193","issn":["1758-9193"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's Research & Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7246000170707703,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1455163141","display_name":null,"funder_award_id":"CBRC 161","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G1509129543","display_name":null,"funder_award_id":"091673","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G3891406106","display_name":"Profiling dementias using complex sound: from symptoms to brain networks.","funder_award_id":"091673","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G4002639776","display_name":"The UK GENetic Frontotemporal dementia Initiative (UK GENFI)","funder_award_id":"MR/M023664/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4147912979","display_name":"A next-generation MRI brain imaging platform for dementia research: from microstructure to function","funder_award_id":"MR/M009106/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4649687622","display_name":"Profiling dementias using complex sound: from symptoms to brain networks.","funder_award_id":"091673/Z/10/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G5096617844","display_name":null,"funder_award_id":"AS-PG-16-007","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5488061247","display_name":"The GENetic Frontotemporal Dementia Initiative (GENFI): a new multi-centre platform for the study of frontotemporal lobar degeneration","funder_award_id":"MR/J009482/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G7100066897","display_name":null,"funder_award_id":"AS\u2010PG\u201016\u2010007","funder_id":"https://openalex.org/F4320317015","funder_display_name":"Alzheimer's Society"},{"id":"https://openalex.org/G7697514025","display_name":null,"funder_award_id":"PR/ylr/18575","funder_id":"https://openalex.org/F4320320286","funder_display_name":"University College London"},{"id":"https://openalex.org/G8620215749","display_name":null,"funder_award_id":"CL-2012-18-010","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G8907892866","display_name":"Developing an evidence base for trials in genetic frontotemporal dementia - measures of disease onset and progression","funder_award_id":"MR/M008525/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G942021869","display_name":null,"funder_award_id":"PR/ylr/18575","funder_id":"https://openalex.org/F4320320670","funder_display_name":"Wolfson Foundation"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320316138","display_name":"National Brain Appeal","ror":"https://ror.org/05q54d222"},{"id":"https://openalex.org/F4320317015","display_name":"Alzheimer's Society","ror":"https://ror.org/0472gwq90"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320286","display_name":"University College London","ror":"https://ror.org/02jx3x895"},{"id":"https://openalex.org/F4320320670","display_name":"Wolfson Foundation","ror":"https://ror.org/0333xzh65"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2740976277.pdf","grobid_xml":"https://content.openalex.org/works/W2740976277.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1965248225","https://openalex.org/W1967549735","https://openalex.org/W1972685664","https://openalex.org/W1977257077","https://openalex.org/W2021577051","https://openalex.org/W2032230668","https://openalex.org/W2056905945","https://openalex.org/W2057789685","https://openalex.org/W2060256270","https://openalex.org/W2065249820","https://openalex.org/W2071383468","https://openalex.org/W2072200528","https://openalex.org/W2092008289","https://openalex.org/W2092952432","https://openalex.org/W2098567201","https://openalex.org/W2098708841","https://openalex.org/W2099239745","https://openalex.org/W2101135654","https://openalex.org/W2107544270","https://openalex.org/W2109023847","https://openalex.org/W2111626663","https://openalex.org/W2119548591","https://openalex.org/W2124590545","https://openalex.org/W2126754916","https://openalex.org/W2130888418","https://openalex.org/W2131379034","https://openalex.org/W2138190873","https://openalex.org/W2139269757","https://openalex.org/W2148384586","https://openalex.org/W2151427255","https://openalex.org/W2160197447","https://openalex.org/W2163668761","https://openalex.org/W2169287078","https://openalex.org/W2327261939","https://openalex.org/W2460879673","https://openalex.org/W2466884519","https://openalex.org/W2531312585","https://openalex.org/W2556590024","https://openalex.org/W2612092148","https://openalex.org/W2625796101","https://openalex.org/W2774782774","https://openalex.org/W2808155566"],"related_works":["https://openalex.org/W6958306447","https://openalex.org/W2098708841","https://openalex.org/W2619028037","https://openalex.org/W6939237889","https://openalex.org/W2768961847","https://openalex.org/W6976844216","https://openalex.org/W6976735804","https://openalex.org/W2111626663","https://openalex.org/W4386157365","https://openalex.org/W2327261939"],"abstract_inverted_index":{"BACKGROUND:":[0],"Non-verbal":[1],"auditory":[2,63,231],"impairment":[3],"is":[4],"increasingly":[5],"recognised":[6],"in":[7,31,52,147,175,195,212],"the":[8,34,121,137,161,166,176,186,196,203,213,242],"primary":[9],"progressive":[10],"aphasias":[11],"(PPAs)":[12],"but":[13],"its":[14],"relationship":[15],"to":[16,54,88,117],"speech":[17,148],"processing":[18,128,143,188],"and":[19,38,69,98,123,133,157,181,200,252],"brain":[20,111],"substrates":[21],"has":[22,247],"not":[23],"been":[24],"defined.":[25],"Here":[26],"we":[27],"addressed":[28],"these":[29,90],"issues":[30],"patients":[32,49],"representing":[33],"non-fluent":[35],"variant":[36,40],"(nfvPPA)":[37],"semantic":[39],"(svPPA)":[41],"syndromes":[42,222],"of":[43,74,81,86,101,109,129,144,230],"PPA.":[44],"METHODS:":[45],"We":[46,59],"studied":[47],"19":[48,55],"with":[50,153,172,192,209,234],"PPA":[51,221],"relation":[53],"healthy":[56,118],"older":[57],"individuals.":[58],"manipulated":[60],"three":[61],"key":[62],"parameters-temporal":[64],"regularity,":[65],"phonemic":[66,130],"spectral":[67,131],"structure":[68,132],"prosodic":[70,204],"predictability":[71,135,205],"(an":[72],"index":[73],"fundamental":[75],"information":[76],"content,":[77],"or":[78],"entropy)-in":[79],"sequences":[80],"spoken":[82],"syllables.":[83],"The":[84],"ability":[85],"participants":[87],"process":[89],"parameters":[91],"was":[92,170,190,207],"assessed":[93,105],"using":[94,106],"two-alternative,":[95],"forced-choice":[96],"tasks":[97],"neuroanatomical":[99],"associations":[100],"task":[102,169,189,206],"performance":[103,151,164,184,201],"were":[104],"voxel-based":[107],"morphometry":[108],"patients'":[110],"magnetic":[112],"resonance":[113],"images.":[114],"RESULTS:":[115],"Relative":[116],"controls,":[119],"both":[120],"nfvPPA":[122,138],"svPPA":[124],"groups":[125],"had":[126,141],"impaired":[127,142],"signal":[134,232],"while":[136],"group":[139],"additionally":[140],"temporal":[145,167],"regularity":[146,168],"signals.":[149],"Task":[150],"correlated":[152],"standard":[154],"disease":[155],"severity":[156],"neurolinguistic":[158],"measures.":[159],"Across":[160],"patient":[162],"cohort,":[163],"on":[165,185,202],"associated":[171,191,208],"grey":[173,193,210],"matter":[174,194,211],"left":[177,197],"supplementary":[178],"motor":[179],"area":[180],"right":[182,214],"caudate,":[183],"phoneme":[187],"supramarginal":[198],"gyrus,":[199],"putamen.":[215],"CONCLUSIONS:":[216],"Our":[217],"findings":[218],"suggest":[219],"that":[220],"may":[223],"be":[224],"underpinned":[225],"by":[226],"more":[227],"generic":[228],"deficits":[229],"analysis,":[233],"a":[235],"distributed":[236],"cortico-subcortical":[237],"neuraoanatomical":[238],"substrate":[239],"extending":[240],"beyond":[241],"canonical":[243],"language":[244],"network.":[245],"This":[246],"implications":[248],"for":[249],"syndrome":[250],"classification":[251],"biomarker":[253],"development.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-08-08T00:00:00"}