{"id":"https://openalex.org/W2740964166","doi":"https://doi.org/10.1016/j.bbagen.2017.07.023","title":"Sialidase NEU3 defines invasive potential of human glioblastoma cells by regulating calpain-mediated proteolysis of focal adhesion proteins","display_name":"Sialidase NEU3 defines invasive potential of human glioblastoma cells by regulating calpain-mediated proteolysis of focal adhesion proteins","publication_year":2017,"publication_date":"2017-07-29","ids":{"openalex":"https://openalex.org/W2740964166","doi":"https://doi.org/10.1016/j.bbagen.2017.07.023","mag":"2740964166","pmid":"https://pubmed.ncbi.nlm.nih.gov/28760640"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbagen.2017.07.023","doi":"https://doi.org/10.1016/j.bbagen.2017.07.023","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2017.07.023","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100668864","display_name":"Kohta Takahashi","orcid":"https://orcid.org/0009-0007-1466-9126","observed_orcids":["https://orcid.org/0009-0007-1466-9126","https://orcid.org/0000-0001-9499-9035"]},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kohta Takahashi","raw_affiliation_strings":["Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan","Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan","Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan","institution_ids":["https://openalex.org/I85324120"]},{"raw_affiliation_string":"Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan","institution_ids":["https://openalex.org/I85324120"]},{"raw_affiliation_string":"Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan","institution_ids":["https://openalex.org/I85324120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037130368","display_name":"Sergei N. Proshin","orcid":"https://orcid.org/0000-0001-9720-4381","observed_orcids":["https://orcid.org/0000-0001-9720-4381"]},"institutions":[{"id":"https://openalex.org/I74756048","display_name":"Saint Petersburg State Pediatric Medical University","ror":"https://ror.org/000hzy098","country_code":"RU","type":"education","lineage":["https://openalex.org/I74756048"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Sergei Proshin","raw_affiliation_strings":["St Petersburg State Pediatric Medical University, Litovskaya ul., 2, St Petersburg, 194100, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St Petersburg State Pediatric Medical University, Litovskaya ul., 2, St Petersburg, 194100, Russia","institution_ids":["https://openalex.org/I74756048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029259830","display_name":"Kazunori Yamaguchi","orcid":"https://orcid.org/0000-0003-0383-7386","observed_orcids":["https://orcid.org/0000-0003-0383-7386","https://orcid.org/0009-0007-0523-7225"]},"institutions":[{"id":"https://openalex.org/I4210107389","display_name":"Miyagi Prefectural Hospital Organization","ror":"https://ror.org/01qt7mp11","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210107389"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazunori Yamaguchi","raw_affiliation_strings":["Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, Natori, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Molecular and Cellular Oncology, Miyagi Cancer Center Research Institute, Natori, Japan","institution_ids":["https://openalex.org/I4210107389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101112775","display_name":"Yoji Yamashita","orcid":"https://orcid.org/0009-0009-0998-4193","observed_orcids":["https://orcid.org/0009-0009-0998-4193"]},"institutions":[{"id":"https://openalex.org/I4210107389","display_name":"Miyagi Prefectural Hospital Organization","ror":"https://ror.org/01qt7mp11","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210107389"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoji Yamashita","raw_affiliation_strings":["Department of Neurosurgery, Miyagi Cancer Center, Natori, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Miyagi Cancer Center, Natori, Japan","institution_ids":["https://openalex.org/I4210107389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040397242","display_name":"Ryuichi Katakura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107389","display_name":"Miyagi Prefectural Hospital Organization","ror":"https://ror.org/01qt7mp11","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210107389"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryuichi Katakura","raw_affiliation_strings":["Department of Neurosurgery, Miyagi Cancer Center, Natori, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Miyagi Cancer Center, Natori, Japan","institution_ids":["https://openalex.org/I4210107389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105411014","display_name":"Koji Yamamoto","orcid":"https://orcid.org/0000-0002-8406-0865","observed_orcids":["https://orcid.org/0000-0002-8406-0865"]},"institutions":[{"id":"https://openalex.org/I4210107389","display_name":"Miyagi Prefectural Hospital Organization","ror":"https://ror.org/01qt7mp11","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210107389"]},{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Yamamoto","raw_affiliation_strings":["Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","institution_ids":["https://openalex.org/I4210107389","https://openalex.org/I85324120"]},{"raw_affiliation_string":"Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","institution_ids":["https://openalex.org/I4210107389"]},{"raw_affiliation_string":"Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan","institution_ids":["https://openalex.org/I85324120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013218910","display_name":"Hiroshi Shima","orcid":"https://orcid.org/0000-0002-0857-8929","observed_orcids":["https://orcid.org/0000-0002-0857-8929"]},"institutions":[{"id":"https://openalex.org/I4210107389","display_name":"Miyagi Prefectural Hospital Organization","ror":"https://ror.org/01qt7mp11","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210107389"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Shima","raw_affiliation_strings":["Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","institution_ids":["https://openalex.org/I4210107389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054954409","display_name":"Masahiro Hosono","orcid":"https://orcid.org/0000-0003-0663-5560","observed_orcids":["https://orcid.org/0000-0003-0663-5560"]},"institutions":[{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Masahiro Hosono","raw_affiliation_strings":["Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan. Electronic address: mhosono@tohoku-mpu.ac.jp","Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan. Electronic address: mhosono@tohoku-mpu.ac.jp","institution_ids":["https://openalex.org/I85324120"]},{"raw_affiliation_string":"Division of Cell Recognition Study, Tohoku Medical and Pharmaceutical University, Sendai, Japan","institution_ids":["https://openalex.org/I85324120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103407743","display_name":"Taeko Miyagi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107389","display_name":"Miyagi Prefectural Hospital Organization","ror":"https://ror.org/01qt7mp11","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210107389"]},{"id":"https://openalex.org/I85324120","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45","country_code":"JP","type":"education","lineage":["https://openalex.org/I85324120"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Taeko Miyagi","raw_affiliation_strings":["Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan. Electronic address: miyagi-ta@nifty.com","Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan; Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan. Electronic address: miyagi-ta@nifty.com","institution_ids":["https://openalex.org/I4210107389","https://openalex.org/I85324120"]},{"raw_affiliation_string":"Division of Cancer Chemotherapy, Miyagi Cancer Center Research Institute, Natori, Japan","institution_ids":["https://openalex.org/I4210107389"]},{"raw_affiliation_string":"Division of Cancer Glycosylation Research, Tohoku Medical and Pharmaceutical University, Sendai, Japan","institution_ids":["https://openalex.org/I85324120"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5054954409","https://openalex.org/A5103407743"],"corresponding_institution_ids":["https://openalex.org/I4210107389","https://openalex.org/I85324120"],"apc_list":{"value":3310,"currency":"USD","value_usd":3310},"apc_paid":null,"fwci":0.8763,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.68812102,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"1861","issue":"11","first_page":"2778","last_page":"2788"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9243000149726868,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9243000149726868,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.04729999974370003,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13637","display_name":"Calpain Protease Function and Regulation","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":0.8809999823570251},{"id":"https://openalex.org/keywords/tumor-invasion","display_name":"tumor invasion","score":0.875},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.8560000061988831},{"id":"https://openalex.org/keywords/focal-adhesions","display_name":"focal adhesions","score":0.7910000085830688},{"id":"https://openalex.org/keywords/calpain","display_name":"calpain","score":0.8479999899864197},{"id":"https://openalex.org/keywords/proteolysis","display_name":"proteolysis","score":0.8700000047683716},{"id":"https://openalex.org/keywords/gangliosides","display_name":"gangliosides","score":0.9309999942779541},{"id":"https://openalex.org/keywords/gm3-ganglioside","display_name":"GM3 ganglioside","score":0.7739999890327454},{"id":"https://openalex.org/keywords/sialic-acid","display_name":"sialic acid","score":0.953000009059906},{"id":"https://openalex.org/keywords/lamellipodia","display_name":"lamellipodia","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C73695083","wikidata":"https://www.wikidata.org/wiki/Q409485","display_name":"Sialidase","level":4,"score":0.7746851444244385},{"id":"https://openalex.org/C151166631","wikidata":"https://www.wikidata.org/wiki/Q904514","display_name":"Focal adhesion","level":3,"score":0.6672730445861816},{"id":"https://openalex.org/C56928146","wikidata":"https://www.wikidata.org/wiki/Q2934402","display_name":"Calpain","level":3,"score":0.6476114988327026},{"id":"https://openalex.org/C109185818","wikidata":"https://www.wikidata.org/wiki/Q3092607","display_name":"Lamellipodium","level":4,"score":0.6340907216072083},{"id":"https://openalex.org/C11957725","wikidata":"https://www.wikidata.org/wiki/Q5533590","display_name":"Gentamicin protection assay","level":4,"score":0.5167917013168335},{"id":"https://openalex.org/C137738243","wikidata":"https://www.wikidata.org/wiki/Q189092","display_name":"Cell migration","level":3,"score":0.5145215392112732},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5048078298568726},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5031148791313171},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4769017696380615},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46974900364875793},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.4526800513267517},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.41571980714797974},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.39588889479637146},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.36604538559913635},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.22831040620803833},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19648346304893494},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.07485288381576538},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C134164806","wikidata":"https://www.wikidata.org/wiki/Q409485","display_name":"Neuraminidase","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D002154","descriptor_name":"Calpain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009439","descriptor_name":"Neuraminidase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022001","descriptor_name":"Focal Adhesions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D059748","descriptor_name":"Proteolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bbagen.2017.07.023","doi":"https://doi.org/10.1016/j.bbagen.2017.07.023","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbagen.2017.07.023","pdf_url":null,"source":{"id":"https://openalex.org/S4210238601","display_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","issn_l":"0304-4165","issn":["0304-4165","1872-8006"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - General Subjects","raw_type":"journal-article"},{"id":"pmid:28760640","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28760640","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta. General subjects","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7023922681","display_name":null,"funder_award_id":"24110514","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G7968527613","display_name":"Tumorigenesis due to dysfunction of PP6, a novel target for cancer treatment.","funder_award_id":"17K07187","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8429299986","display_name":"Identification of a protein phosphatase which involved in brain tumororigenesis.","funder_award_id":"16K10774","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320307856","display_name":"World Health Organization","ror":"https://ror.org/01f80g185"},{"id":"https://openalex.org/F4320315548","display_name":"Tohoku Medical and Pharmaceutical University","ror":"https://ror.org/0264zxa45"},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1579005511","https://openalex.org/W1607971762","https://openalex.org/W1965623168","https://openalex.org/W1974405791","https://openalex.org/W1975734060","https://openalex.org/W1979448798","https://openalex.org/W1980967211","https://openalex.org/W1986508144","https://openalex.org/W1987875997","https://openalex.org/W1995434225","https://openalex.org/W2003679206","https://openalex.org/W2004748537","https://openalex.org/W2007871259","https://openalex.org/W2008495749","https://openalex.org/W2009148873","https://openalex.org/W2024164125","https://openalex.org/W2028175838","https://openalex.org/W2034437737","https://openalex.org/W2036044314","https://openalex.org/W2038062002","https://openalex.org/W2045009404","https://openalex.org/W2052094618","https://openalex.org/W2053879820","https://openalex.org/W2056489977","https://openalex.org/W2068533231","https://openalex.org/W2070336139","https://openalex.org/W2072397543","https://openalex.org/W2085019946","https://openalex.org/W2095764561","https://openalex.org/W2096469690","https://openalex.org/W2103246127","https://openalex.org/W2106621127","https://openalex.org/W2131223750","https://openalex.org/W2135936050","https://openalex.org/W2166798417","https://openalex.org/W2184902992","https://openalex.org/W2264866277","https://openalex.org/W2346144030","https://openalex.org/W2361429235","https://openalex.org/W2409071334","https://openalex.org/W2593174622","https://openalex.org/W6680323195","https://openalex.org/W6713963715"],"related_works":["https://openalex.org/W4237868874","https://openalex.org/W3174755661","https://openalex.org/W2003679206","https://openalex.org/W2073834135","https://openalex.org/W7101078713","https://openalex.org/W6906662572","https://openalex.org/W2012245232","https://openalex.org/W4386825520","https://openalex.org/W2113163631","https://openalex.org/W2901686834"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-08-08T00:00:00"}
