{"id":"https://openalex.org/W2740919264","doi":"https://doi.org/10.1016/j.stemcr.2017.06.017","title":"Mir-29b Mediates the Neural Tube versus Neural Crest Fate Decision during Embryonic Stem Cell Neural Differentiation","display_name":"Mir-29b Mediates the Neural Tube versus Neural Crest Fate Decision during Embryonic Stem Cell Neural Differentiation","publication_year":2017,"publication_date":"2017-07-27","ids":{"openalex":"https://openalex.org/W2740919264","doi":"https://doi.org/10.1016/j.stemcr.2017.06.017","mag":"2740919264","pmid":"https://pubmed.ncbi.nlm.nih.gov/28757169","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5550033"},"language":"en","primary_location":{"id":"doi:10.1016/j.stemcr.2017.06.017","doi":"https://doi.org/10.1016/j.stemcr.2017.06.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stemcr.2017.06.017","pdf_url":"http://www.cell.com/article/S2213671117302801/pdf","source":{"id":"https://openalex.org/S2764425922","display_name":"Stem Cell Reports","issn_l":"2213-6711","issn":["2213-6711"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.cell.com/article/S2213671117302801/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022050121","display_name":"Jiajie Xi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiajie Xi","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112143486","display_name":"Yukang Wu","orcid":"https://orcid.org/0000-0001-8165-5428","observed_orcids":["https://orcid.org/0000-0001-8165-5428"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yukang Wu","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100398918","display_name":"Guoping Li","orcid":"https://orcid.org/0000-0003-3874-0744","observed_orcids":["https://orcid.org/0000-0003-3874-0744"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guoping Li","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100706321","display_name":"Li Ma","orcid":"https://orcid.org/0009-0009-5892-228X","observed_orcids":["https://orcid.org/0009-0009-5892-228X","https://orcid.org/0000-0003-4093-4791"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Ma","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ke Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ke Feng","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054726963","display_name":"Xudong Guo","orcid":"https://orcid.org/0000-0002-7720-1885","observed_orcids":["https://orcid.org/0000-0002-7720-1885","https://orcid.org/0009-0009-9491-4359"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xudong Guo","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022228465","display_name":"Wenwen Jia","orcid":"https://orcid.org/0000-0001-5969-3751","observed_orcids":["https://orcid.org/0000-0001-5969-3751"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenwen Jia","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100692454","display_name":"Guiying Wang","orcid":"https://orcid.org/0000-0001-6415-818X","observed_orcids":["https://orcid.org/0000-0001-6415-818X"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guiying Wang","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101942101","display_name":"Guang Yang","orcid":"https://orcid.org/0000-0002-1910-9271","observed_orcids":["https://orcid.org/0000-0002-1910-9271","https://orcid.org/0000-0003-4661-6022"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guang Yang","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100435517","display_name":"Ping Li","orcid":"https://orcid.org/0000-0002-4492-4825","observed_orcids":["https://orcid.org/0000-0002-4492-4825"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ping Li","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China. Electronic address: liping01@tongji.edu.cn","Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China. Electronic address: liping01@tongji.edu.cn","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088327696","display_name":"Jiuhong Kang","orcid":"https://orcid.org/0000-0001-7538-1889","observed_orcids":["https://orcid.org/0000-0001-7538-1889"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210153623","display_name":"Shanghai First Maternity and Infant Hospital","ror":"https://ror.org/05myyzn85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153623"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiuhong Kang","raw_affiliation_strings":["Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China; The Collaborative Innovation Center for Brain Science, Tongji University, Shanghai 200092, PR China. Electronic address: jhkang@tongji.edu.cn","Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","The Collaborative Innovation Center for Brain Science, Tongji University, Shanghai 200092, PR China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China; The Collaborative Innovation Center for Brain Science, Tongji University, Shanghai 200092, PR China. Electronic address: jhkang@tongji.edu.cn","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, 1239 Siping Road, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"]},{"raw_affiliation_string":"The Collaborative Innovation Center for Brain Science, Tongji University, Shanghai 200092, PR China","institution_ids":["https://openalex.org/I116953780"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5088327696","https://openalex.org/A5100435517"],"corresponding_institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210153623"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":{"value":4190,"currency":"USD","value_usd":4190},"fwci":0.8763,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.68812102,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"9","issue":"2","first_page":"571","last_page":"586"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.888700008392334,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.888700008392334,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.0640999972820282,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.03689999878406525,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mir-29b","display_name":"miR-29b","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neural-tube","display_name":"neural tube","score":0.6579999923706055},{"id":"https://openalex.org/keywords/neural-crest","display_name":"neural crest","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cell-fate-determination","display_name":"cell fate determination","score":0.7730000019073486},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.6100000143051147},{"id":"https://openalex.org/keywords/dnmt3a","display_name":"DNMT3A","score":0.8949999809265137},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8619999885559082},{"id":"https://openalex.org/keywords/pou3f1","display_name":"POU3F1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neuroectoderm","display_name":"neuroectoderm","score":0.7540000081062317}],"concepts":[{"id":"https://openalex.org/C126749454","wikidata":"https://www.wikidata.org/wiki/Q1348455","display_name":"Neural crest","level":3,"score":0.8096256256103516},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7969872951507568},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.6409343481063843},{"id":"https://openalex.org/C2780594696","wikidata":"https://www.wikidata.org/wiki/Q1127402","display_name":"Neural tube","level":3,"score":0.6082680225372314},{"id":"https://openalex.org/C197849852","wikidata":"https://www.wikidata.org/wiki/Q2314823","display_name":"Neural plate","level":4,"score":0.5837111473083496},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5834145545959473},{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.5497605204582214},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.540201723575592},{"id":"https://openalex.org/C135073763","wikidata":"https://www.wikidata.org/wiki/Q1271432","display_name":"Neuroectoderm","level":5,"score":0.48951447010040283},{"id":"https://openalex.org/C461258","wikidata":"https://www.wikidata.org/wiki/Q1345738","display_name":"Neural development","level":3,"score":0.4671342372894287},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.427661657333374},{"id":"https://openalex.org/C2992459734","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neural cell","level":3,"score":0.4127698540687561},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.3823254108428955},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34912022948265076},{"id":"https://openalex.org/C2780915607","wikidata":"https://www.wikidata.org/wiki/Q323438","display_name":"Mesoderm","level":4,"score":0.25978749990463257},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.24742034077644348},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1918272078037262},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.17160862684249878},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.04780101776123047}],"mesh":[{"descriptor_ui":"D000090205","descriptor_name":"DNA Methyltransferase 3A","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004248","descriptor_name":"DNA (Cytosine-5-)-Methyltransferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004248","descriptor_name":"DNA (Cytosine-5-)-Methyltransferases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D009432","descriptor_name":"Neural Crest","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D050816","descriptor_name":"Octamer Transcription Factor-6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D053595","descriptor_name":"Embryonic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054259","descriptor_name":"Neural Tube","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D054259","descriptor_name":"Neural Tube","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.stemcr.2017.06.017","doi":"https://doi.org/10.1016/j.stemcr.2017.06.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stemcr.2017.06.017","pdf_url":"http://www.cell.com/article/S2213671117302801/pdf","source":{"id":"https://openalex.org/S2764425922","display_name":"Stem Cell Reports","issn_l":"2213-6711","issn":["2213-6711"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"journal-article"},{"id":"pmid:28757169","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28757169","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem cell reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5550033","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5550033/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:3be1a8bc776e499c8dfc302207c70fad","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/3be1a8bc776e499c8dfc302207c70fad","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Stem Cell Reports, Vol 9, Iss 2, Pp 571-586 (2017)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.stemcr.2017.06.017","doi":"https://doi.org/10.1016/j.stemcr.2017.06.017","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.stemcr.2017.06.017","pdf_url":"http://www.cell.com/article/S2213671117302801/pdf","source":{"id":"https://openalex.org/S2764425922","display_name":"Stem Cell Reports","issn_l":"2213-6711","issn":["2213-6711"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stem Cell Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1067238068","display_name":"\u7279\u5b9alincRNA\u5728\u4f53\u7ec6\u80de\u91cd\u7f16\u7a0b\u4e2d\u7684\u529f\u80fd\u4e0e\u673a\u5236","funder_award_id":"31371510","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G217536862","display_name":null,"funder_award_id":"31471250","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2607426931","display_name":null,"funder_award_id":"15JC1403200","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G4453765578","display_name":null,"funder_award_id":"2013CB967401","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G4558456161","display_name":null,"funder_award_id":"31401257","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4796822814","display_name":"\u975e\u7f16\u7801RNA\u5728\u795e\u7ecf\u7cfb\u7edf\u80ce\u6e90\u6027\u75be\u75c5\u4e2d\u7684\u4f5c\u7528\u548c\u673a\u5236\u7814\u7a76","funder_award_id":"81530042","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6467452167","display_name":null,"funder_award_id":"31210103905","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6621026971","display_name":null,"funder_award_id":"91519320","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6961733425","display_name":null,"funder_award_id":"15JC1403201","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"},{"id":"https://openalex.org/G7586849747","display_name":null,"funder_award_id":"2016YFA0101300","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G7617480953","display_name":"HDAC10\u6838\u8d28\u5b9a\u4f4d\u53ca\u5176\u4ecb\u5bfc\u7684\u81ea\u566c\u4f5c\u7528\u5728\u80ba\u764c\u4e2d\u7684\u529f\u80fd\u548c\u673a\u5236\u7814\u7a76","funder_award_id":"31571390","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7673602357","display_name":"lncRNA\u5728\u5e72\u7ec6\u80de\u591a\u80fd\u6027\u7ef4\u6301\u548c\u8d28\u91cf\u5dee\u5f02\u4e2d\u7684\u4f5c\u7528\u4e0e\u8c03\u63a7\u673a\u5236","funder_award_id":"31571519","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7880349491","display_name":null,"funder_award_id":"IRT_15R51","funder_id":"https://openalex.org/F4320321106","funder_display_name":"Ministry of Education of the People's Republic of China"},{"id":"https://openalex.org/G8626020913","display_name":"LincRNA-Hrt\u5728\u80da\u80ce\u5e72\u7ec6\u80de\u5411\u5fc3\u808c\u7ec6\u80de\u5206\u5316\u8fc7\u7a0b\u4e2d\u7684\u5206\u5b50\u673a\u5236\u7814\u7a76","funder_award_id":"31571529","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8751120467","display_name":null,"funder_award_id":"2013CB967600","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G994145353","display_name":null,"funder_award_id":"31401126","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321106","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934"},{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2740919264.pdf"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1839314511","https://openalex.org/W1925932947","https://openalex.org/W1930352947","https://openalex.org/W1963820950","https://openalex.org/W1969717239","https://openalex.org/W1970774026","https://openalex.org/W1970867422","https://openalex.org/W1972989638","https://openalex.org/W1979099854","https://openalex.org/W1982532675","https://openalex.org/W1983861034","https://openalex.org/W1984893258","https://openalex.org/W1988922014","https://openalex.org/W1993909108","https://openalex.org/W2000418014","https://openalex.org/W2003906576","https://openalex.org/W2005491819","https://openalex.org/W2016606965","https://openalex.org/W2017408113","https://openalex.org/W2027030154","https://openalex.org/W2033284482","https://openalex.org/W2037686178","https://openalex.org/W2038442934","https://openalex.org/W2045899482","https://openalex.org/W2072810552","https://openalex.org/W2077720819","https://openalex.org/W2081144380","https://openalex.org/W2083245183","https://openalex.org/W2086943348","https://openalex.org/W2087028472","https://openalex.org/W2093281361","https://openalex.org/W2096409066","https://openalex.org/W2096715639","https://openalex.org/W2097400599","https://openalex.org/W2109262751","https://openalex.org/W2113521816","https://openalex.org/W2116467413","https://openalex.org/W2117710640","https://openalex.org/W2133764144","https://openalex.org/W2133938268","https://openalex.org/W2137247854","https://openalex.org/W2141310488","https://openalex.org/W2149683063","https://openalex.org/W2157009395","https://openalex.org/W2159678445","https://openalex.org/W2161272397","https://openalex.org/W2163538755","https://openalex.org/W2165621629","https://openalex.org/W2344746168"],"related_works":["https://openalex.org/W7039657318","https://openalex.org/W3028352444","https://openalex.org/W2799538301","https://openalex.org/W1942807334","https://openalex.org/W2741088600","https://openalex.org/W2139484497","https://openalex.org/W2165621629","https://openalex.org/W2478020507","https://openalex.org/W2100358595","https://openalex.org/W2085516803"],"abstract_inverted_index":{"During":[0],"gastrulation,":[1],"the":[2,6,23,29,70,84,90,113,127,134,142],"neuroectoderm":[3],"cells":[4,33,39,43,63,76],"form":[5],"neural":[7,10,35,41,52,108,119,138],"tube":[8,36],"and":[9,40,64,77,140],"crest.":[11],"The":[12],"nervous":[13],"system":[14],"contains":[15],"significantly":[16,88],"more":[17],"microRNAs":[18,26],"than":[19],"other":[20],"tissues,":[21],"but":[22],"role":[24],"of":[25,31,72,86,92,115,137,144],"in":[27,61,66],"controlling":[28],"differentiation":[30,53,71,80,91,139],"neuroectodermal":[32],"into":[34,74,81],"epithelial":[37],"(NTE)":[38],"crest":[42],"(NCCs)":[44],"remains":[45],"unknown.":[46],"Using":[47],"embryonic":[48],"stem":[49],"cell":[50,145],"(ESC)":[51],"systems,":[54],"we":[55],"found":[56],"that":[57,99,126],"miR-29b":[58,87,100,111],"was":[59,131],"upregulated":[60],"NTE":[62,75,93],"downregulated":[65],"NCCs.":[67,82],"MiR-29b":[68],"promoted":[69],"ESCs":[73],"inhibited":[78,89],"their":[79],"Accordingly,":[83],"inhibition":[85],"cells.":[94],"A":[95],"mechanistic":[96],"study":[97,124],"revealed":[98],"targets":[101],"DNA":[102],"methyltransferase":[103],"3a":[104],"(Dnmt3a)":[105],"to":[106],"regulate":[107],"differentiation.":[109],"Moreover,":[110],"mediated":[112],"function":[114],"Pou3f1,":[116],"a":[117],"critical":[118],"transcription":[120],"factor.":[121],"Therefore,":[122],"our":[123],"showed":[125],"Pou3f1-miR-29b-Dnmt3a":[128],"regulatory":[129],"axis":[130],"active":[132],"at":[133],"initial":[135],"stage":[136],"regulated":[141],"determination":[143],"fate.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2017-08-08T00:00:00"}