{"id":"https://openalex.org/W274040583","doi":"https://doi.org/10.1080/00021369.1986.10867685","title":"Chemical and Toxicological Studies of the Phytotoxin, 6\u03b1,7\u03b2,9\u03b1-Trihydroxy-8(14), 15-isopimaradiene-20,6-\u03b3-lactone, Produced by a Parasitic Fungus,Phomopsissp., in Wilting Pine Trees","display_name":"Chemical and Toxicological Studies of the Phytotoxin, 6\u03b1,7\u03b2,9\u03b1-Trihydroxy-8(14), 15-isopimaradiene-20,6-\u03b3-lactone, Produced by a Parasitic Fungus,Phomopsissp., in Wilting Pine Trees","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W274040583","doi":"https://doi.org/10.1080/00021369.1986.10867685","mag":"274040583"},"language":"en","primary_location":{"id":"doi:10.1080/00021369.1986.10867685","doi":"https://doi.org/10.1080/00021369.1986.10867685","is_oa":false,"landing_page_url":"https://doi.org/10.1080/00021369.1986.10867685","pdf_url":null,"source":{"id":"https://openalex.org/S2764346059","display_name":"Agricultural and Biological Chemistry","issn_l":"0002-1369","issn":["0002-1369","0375-8397","1881-1272","1881-1280"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agricultural and Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/bbb1961/50/8/50_8_2003/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113584506","display_name":"NOBUHISA MOROOKA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuhisa Morooka","raw_affiliation_strings":["The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","The Institute of Physical and Chemical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","institution_ids":["https://openalex.org/I4210110652"]},{"raw_affiliation_string":"The Institute of Physical and Chemical Research","institution_ids":["https://openalex.org/I4210110652"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102089678","display_name":"Takashi Tatsuno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Tatsuno","raw_affiliation_strings":["The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","The Institute of Physical and Chemical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","institution_ids":["https://openalex.org/I4210110652"]},{"raw_affiliation_string":"The Institute of Physical and Chemical Research","institution_ids":["https://openalex.org/I4210110652"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010048897","display_name":"Hiroshi Tsunoda","orcid":"https://orcid.org/0000-0001-6214-5625","observed_orcids":["https://orcid.org/0000-0001-6214-5625"]},"institutions":[{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi Tsunoda","raw_affiliation_strings":["The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","The Institute of Physical and Chemical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","institution_ids":["https://openalex.org/I4210110652"]},{"raw_affiliation_string":"The Institute of Physical and Chemical Research","institution_ids":["https://openalex.org/I4210110652"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109107096","display_name":"Kimiko Kobayashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kimiko Kobayashi","raw_affiliation_strings":["The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","The Institute of Physical and Chemical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","institution_ids":["https://openalex.org/I4210110652"]},{"raw_affiliation_string":"The Institute of Physical and Chemical Research","institution_ids":["https://openalex.org/I4210110652"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110058322","display_name":"Tosio Sakurai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tosio Sakurai","raw_affiliation_strings":["The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","The Institute of Physical and Chemical Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute of Physical and Chemical Research, Wako, Sait ama 351, Japan","institution_ids":["https://openalex.org/I4210110652"]},{"raw_affiliation_string":"The Institute of Physical and Chemical Research","institution_ids":["https://openalex.org/I4210110652"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210110652"],"apc_list":null,"apc_paid":null,"fwci":1.6688,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.76014422,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"50","issue":"8","first_page":"2003","last_page":"2007"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12530","display_name":"Bioactive Natural Diterpenoids Research","score":0.5640000104904175,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12530","display_name":"Bioactive Natural Diterpenoids Research","score":0.5640000104904175,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.34619998931884766,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases","score":0.04100000113248825,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/plant-toxins","display_name":"plant toxins","score":0.9179999828338623},{"id":"https://openalex.org/keywords/diaporthe","display_name":"Phomopsis","score":0.9359999895095825},{"id":"https://openalex.org/keywords/pinus-densiflora","display_name":"Pinus densiflora","score":0.9309999942779541},{"id":"https://openalex.org/keywords/pine-wilt-disease","display_name":"pine wilt disease","score":0.6700000166893005},{"id":"https://openalex.org/keywords/stereostructure","display_name":"stereostructure","score":0.5360000133514404},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8389999866485596},{"id":"https://openalex.org/keywords/fungal-metabolite-isolation","display_name":"fungal metabolite isolation","score":0.47699999809265137}],"concepts":[{"id":"https://openalex.org/C2778896499","wikidata":"https://www.wikidata.org/wiki/Q423666","display_name":"Lactol","level":3,"score":0.8972101211547852},{"id":"https://openalex.org/C2775856171","wikidata":"https://www.wikidata.org/wiki/Q1872710","display_name":"Phytotoxin","level":3,"score":0.7258903980255127},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7182673811912537},{"id":"https://openalex.org/C2779678110","wikidata":"https://www.wikidata.org/wiki/Q764","display_name":"Fungus","level":2,"score":0.6492412090301514},{"id":"https://openalex.org/C2776612806","wikidata":"https://www.wikidata.org/wiki/Q59078","display_name":"Lactone","level":2,"score":0.5699824094772339},{"id":"https://openalex.org/C90355303","wikidata":"https://www.wikidata.org/wiki/Q2299244","display_name":"Wilting","level":2,"score":0.5235183835029602},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.46368852257728577},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4497957229614258},{"id":"https://openalex.org/C2778312958","wikidata":"https://www.wikidata.org/wiki/Q7263583","display_name":"Pyricularia","level":2,"score":0.449327290058136},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.4464612603187561},{"id":"https://openalex.org/C2775839086","wikidata":"https://www.wikidata.org/wiki/Q6471530","display_name":"Pathogenic fungus","level":3,"score":0.41386160254478455},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17679259181022644},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1334390640258789},{"id":"https://openalex.org/C2777367657","wikidata":"https://www.wikidata.org/wiki/Q184651","display_name":"Toxin","level":2,"score":0.07033684849739075}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/00021369.1986.10867685","doi":"https://doi.org/10.1080/00021369.1986.10867685","is_oa":false,"landing_page_url":"https://doi.org/10.1080/00021369.1986.10867685","pdf_url":null,"source":{"id":"https://openalex.org/S2764346059","display_name":"Agricultural and Biological Chemistry","issn_l":"0002-1369","issn":["0002-1369","0375-8397","1881-1272","1881-1280"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agricultural and Biological Chemistry","raw_type":"journal-article"},{"id":"doi:10.1271/bbb1961.50.2003","doi":"https://doi.org/10.1271/bbb1961.50.2003","is_oa":true,"landing_page_url":"https://doi.org/10.1271/bbb1961.50.2003","pdf_url":"https://www.jstage.jst.go.jp/article/bbb1961/50/8/50_8_2003/_pdf","source":{"id":"https://openalex.org/S2764346059","display_name":"Agricultural and Biological Chemistry","issn_l":"0002-1369","issn":["0002-1369","0375-8397","1881-1272","1881-1280"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agricultural and Biological Chemistry","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1271/bbb1961.50.2003","doi":"https://doi.org/10.1271/bbb1961.50.2003","is_oa":true,"landing_page_url":"https://doi.org/10.1271/bbb1961.50.2003","pdf_url":"https://www.jstage.jst.go.jp/article/bbb1961/50/8/50_8_2003/_pdf","source":{"id":"https://openalex.org/S2764346059","display_name":"Agricultural and Biological Chemistry","issn_l":"0002-1369","issn":["0002-1369","0375-8397","1881-1272","1881-1280"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agricultural and Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W274040583.pdf","grobid_xml":"https://content.openalex.org/works/W274040583.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4232734298","https://openalex.org/W2521126972","https://openalex.org/W2032113753","https://openalex.org/W1995605102","https://openalex.org/W2156599177","https://openalex.org/W2156577146","https://openalex.org/W2086678398","https://openalex.org/W3194789915","https://openalex.org/W2001263591","https://openalex.org/W2951207959"],"abstract_inverted_index":{"A":[0],"phytotoxin,":[1],"isopimarane":[2,65],"diterpene":[3],"y-lactol,":[4],"6a,7/?,9a-trihydroxy-8(14),1":[5],"5-isopimaradiene-20,6-y-lactone,":[6],"was":[7,19,39,48,66],"isolated":[8],"from":[9,21,76],"the":[10,14,22,26,56,63,67],"culture":[11],"filtrate":[12],"of":[13,25,28,55,62],"fungus":[15,57],"Phomopsis":[16],"sp.,":[17],"which":[18],"obtained":[20],"interior":[23],"part":[24],"trunk":[27],"most":[29],"wilting":[30],"Japanese":[31,77],"red":[32,78],"pines,":[33],"Pinus":[34],"densiflora":[35],"Sieb.et":[36],"Zucc.The":[37],"stereostructure":[38],"established":[40],"by":[41],"X-ray":[42],"crystal":[43],"analysis":[44],"and":[45],"spectroanalysis.This":[46],"y-lactol":[47,64],"identical":[49],"with":[50],"LL-S491,":[51],"a":[52],"fermentation":[53],"product":[54],"Aspergillus":[58],"chevalieri.The":[59],"cytotoxic":[60],"activity":[61],"same":[68],"as":[69],"pentachlorophenol":[70],"at":[71],"150ppm":[72],"on":[73],"cell":[74],"cultures":[75],"pine":[79],"buds.":[80]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}