{"id":"https://openalex.org/W2739965356","doi":null,"title":"DIFFERENT APPROACHES FOR ANTICANCER THERAPY","display_name":"DIFFERENT APPROACHES FOR ANTICANCER THERAPY","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2739965356","mag":"2739965356"},"language":"en","primary_location":{"id":"mag:2739965356","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Mirjana_Pavlovic4/publication/275336799_DIFFERENT_APPROACHES_FOR_ANTICANCER_THERAPY/links/553846bd0cf226723ab62c5d.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010002069","display_name":"Ulrich K. Schreiber","orcid":"https://orcid.org/0000-0002-3775-5058","observed_orcids":["https://orcid.org/0000-0002-3775-5058"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ulrich Schreiber","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3775-5058","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022283228","display_name":"Bela Balint","orcid":"https://orcid.org/0000-0002-3390-1599","observed_orcids":["https://orcid.org/0000-0002-3390-1599","https://orcid.org/0000-0001-5392-1071"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bela Balint","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3390-1599","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5040304302","display_name":"Mirjana D. Pavlovi\u0107","orcid":"https://orcid.org/0000-0003-2894-329X","observed_orcids":["https://orcid.org/0000-0003-2894-329X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mirjana Pavlovi\u0107","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33063712,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Bacterial Cancer Therapy","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-stem-cells","display_name":"cancer stem cells","score":0.9800000190734863},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.6629999876022339},{"id":"https://openalex.org/keywords/cancer-stem-cell-markers","display_name":"cancer stem cell markers","score":0.9480000138282776},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7400000095367432},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.8080000281333923},{"id":"https://openalex.org/keywords/measurable-residual-disease","display_name":"minimal residual disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/magnetic-therapy","display_name":"magnetotherapy","score":0.8199999928474426},{"id":"https://openalex.org/keywords/tumorigenicity","display_name":"tumorigenicity","score":0.6019999980926514}],"concepts":[{"id":"https://openalex.org/C55427017","wikidata":"https://www.wikidata.org/wiki/Q1638475","display_name":"Cancer stem cell","level":3,"score":0.8071985244750977},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.7041561603546143},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5892220139503479},{"id":"https://openalex.org/C2781230642","wikidata":"https://www.wikidata.org/wiki/Q492646","display_name":"Targeted therapy","level":3,"score":0.577907383441925},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5763382315635681},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5182968974113464},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.5138459801673889},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4606175124645233},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35345935821533203},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.329862505197525},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24335449934005737},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.11260756850242615}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2739965356","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Mirjana_Pavlovic4/publication/275336799_DIFFERENT_APPROACHES_FOR_ANTICANCER_THERAPY/links/553846bd0cf226723ab62c5d.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W60759546","https://openalex.org/W67327330","https://openalex.org/W78060682","https://openalex.org/W585828296","https://openalex.org/W1490790087","https://openalex.org/W1539571840","https://openalex.org/W1833694171","https://openalex.org/W1890809256","https://openalex.org/W1892026381","https://openalex.org/W1933173754","https://openalex.org/W1954038871","https://openalex.org/W1983266647","https://openalex.org/W1992676863","https://openalex.org/W2001544973","https://openalex.org/W2005769910","https://openalex.org/W2009886857","https://openalex.org/W2013020286","https://openalex.org/W2018429029","https://openalex.org/W2019264784","https://openalex.org/W2021121983","https://openalex.org/W2023427658","https://openalex.org/W2029231546","https://openalex.org/W2051055358","https://openalex.org/W2052202516","https://openalex.org/W2052275340","https://openalex.org/W2072569544","https://openalex.org/W2073962885","https://openalex.org/W2076922627","https://openalex.org/W2078552560","https://openalex.org/W2079384315","https://openalex.org/W2081447858","https://openalex.org/W2082558506","https://openalex.org/W2097535374","https://openalex.org/W2098950184","https://openalex.org/W2102085111","https://openalex.org/W2105902643","https://openalex.org/W2109134893","https://openalex.org/W2111378248","https://openalex.org/W2112476236","https://openalex.org/W2116336389","https://openalex.org/W2122147062","https://openalex.org/W2130991414","https://openalex.org/W2141393790","https://openalex.org/W2142863599","https://openalex.org/W2149768128","https://openalex.org/W2153017356","https://openalex.org/W2153382986","https://openalex.org/W2156575195","https://openalex.org/W2159880472","https://openalex.org/W2160026729","https://openalex.org/W2168926834","https://openalex.org/W2183451457","https://openalex.org/W2398013626","https://openalex.org/W2405543283","https://openalex.org/W2589848230"],"related_works":["https://openalex.org/W2401438458","https://openalex.org/W2809455661","https://openalex.org/W2136846516","https://openalex.org/W7100077689","https://openalex.org/W4386183089","https://openalex.org/W2914644210","https://openalex.org/W3170169422","https://openalex.org/W2394074912","https://openalex.org/W343229533","https://openalex.org/W4389508910"],"abstract_inverted_index":{"ABSTRACT":[0],"The":[1,39,75,193],"review":[2],"on":[3,78],"classical":[4],"antitumor":[5],"therapy":[6,12,25,206],"including":[7],"the":[8,32,42,47,53,65,86,122,127,144,198],"anticancer":[9],"stem":[10,36,73,93,116,119,159,204],"cell":[11,37,94,205],"novelties":[13],"is":[14,44,207,210,215],"pre-sented":[15],"with":[16],"disadvantages":[17],"and":[18,114,133,140,152,229],"advantages":[19],".The":[20],"concept":[21,33],"of":[22,34,55,88,102,130,143,148,180,197],"targeted":[23,35,202],"tumor":[24,56,112,131,191],"has":[26],"evolved":[27],"during":[28],"last":[29],"years":[30],"into":[31],"therapy.":[38,145],"difference":[40],"between":[41,111],"two":[43],"that":[45,136,212],"in":[46,64,85,126,165,201,217,222],"first":[48],"case":[49,67],"we":[50,68],"are":[51,83,96],"targeting":[52,147,230],"pool":[54,129],"cells":[57,62,113,120,132,154,160],"as":[58,60,98,169,175,195],"well":[59],"normal":[61,153],"while":[63],"second":[66],"should":[69,137],"target":[70,142],"just":[71],"cancer":[72,115,203],"cells.":[74,117,182],"new":[76,89,100],"theories":[77],"Cancer":[79,92,118,158,231],"Stem":[80,232],"Cells":[81],"(CSCs)":[82],"comprehended":[84],"light":[87],"conceptual":[90],"approaches.":[91],"markers":[95],"envisioned":[97],"a":[99,166,176],"category":[101],"biomarkers":[103],"which":[104],"would":[105,155],"be":[106,138,156],"guides":[107],"toward":[108],"precise":[109],"distinction":[110],"have":[121],"highest":[123],"tumorigenic":[124],"potential":[125],"entire":[128],"due":[134,161],"to":[135,162,219],"essential":[139],"primary":[141],"Thus,":[146],"other":[149],"less":[150],"cancer-ogenic":[151],"omitted.":[157],"that,":[163],"reside":[164],"tissues":[167],"either":[168],"minimal":[170],"residual":[171],"disease":[172],"or":[173,187],"simply":[174],"very":[177],"low":[178],"number":[179],"cloned":[181],"When":[183],"reach":[184,220],"critical":[185],"size":[186],"count":[188],"they":[189],"cause":[190],"relapse.":[192],"magnetotherapy":[194],"one":[196],"novel":[199,227],"approaches":[200,228],"described.":[208],"It":[209],"concluded":[211],"further":[213],"research":[214],"necessary":[216],"order":[218],"success":[221],"clinical":[223],"arena":[224],"by":[225],"using":[226],"Cells.":[233]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-08-08T00:00:00"}