{"id":"https://openalex.org/W2739624005","doi":"https://doi.org/10.1007/978-3-319-57424-0_2","title":"The Revival of Patient-Derived Xenograft Mouse Models of Cancer: Way Back to the Future","display_name":"The Revival of Patient-Derived Xenograft Mouse Models of Cancer: Way Back to the Future","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2739624005","doi":"https://doi.org/10.1007/978-3-319-57424-0_2","mag":"2739624005"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-57424-0_2","doi":"https://doi.org/10.1007/978-3-319-57424-0_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-57424-0_2","pdf_url":null,"source":{"id":"https://openalex.org/S4210192819","display_name":"Molecular and translational medicine","issn_l":"2197-7852","issn":["2197-7852","2197-7860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Translational Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2739902236","display_name":"Patient-Derived Mouse Models of Cancer"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040819666","display_name":"Robert M. Hoffman","orcid":"https://orcid.org/0000-0002-0049-0041","observed_orcids":["https://orcid.org/0000-0002-0049-0041"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert M. Hoffman","raw_affiliation_strings":["AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5040819666"],"corresponding_institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210121314"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.17113603,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"7","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9351000189781189,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9351000189781189,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12654","display_name":"Xenotransplantation and immune response","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/patient-derived-xenografts","display_name":"patient-derived xenografts","score":0.9589999914169312},{"id":"https://openalex.org/keywords/mouse-tumor-model","display_name":"mouse tumor model","score":0.6880000233650208},{"id":"https://openalex.org/keywords/orthotopic-xenograft-model","display_name":"orthotopic xenograft","score":0.8119999766349792},{"id":"https://openalex.org/keywords/immunodeficient-mice","display_name":"immunodeficient mice","score":0.8579999804496765},{"id":"https://openalex.org/keywords/subcutaneous-tumor-model","display_name":"subcutaneous tumor model","score":0.6899999976158142},{"id":"https://openalex.org/keywords/history-of-cancer-research","display_name":"history of cancer research","score":0.5460000038146973}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6803922653198242},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5887725353240967},{"id":"https://openalex.org/C2780586970","wikidata":"https://www.wikidata.org/wiki/Q1357284","display_name":"Popularity","level":2,"score":0.466548889875412},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.33228376507759094},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25331228971481323},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1446147859096527},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-319-57424-0_2","doi":"https://doi.org/10.1007/978-3-319-57424-0_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-57424-0_2","pdf_url":null,"source":{"id":"https://openalex.org/S4210192819","display_name":"Molecular and translational medicine","issn_l":"2197-7852","issn":["2197-7852","2197-7860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319972","host_organization_name":"Springer International Publishing","host_organization_lineage":["https://openalex.org/P4310319972","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer International Publishing","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Translational Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W249545773","https://openalex.org/W347202097","https://openalex.org/W1239224350","https://openalex.org/W1492549565","https://openalex.org/W1518520618","https://openalex.org/W1563917378","https://openalex.org/W1569875761","https://openalex.org/W1592125379","https://openalex.org/W1602965390","https://openalex.org/W1805852575","https://openalex.org/W1965550894","https://openalex.org/W1969705513","https://openalex.org/W1990367849","https://openalex.org/W1997855844","https://openalex.org/W1998139955","https://openalex.org/W1998534698","https://openalex.org/W2000844719","https://openalex.org/W2001679453","https://openalex.org/W2026504110","https://openalex.org/W2028701135","https://openalex.org/W2043876651","https://openalex.org/W2052625497","https://openalex.org/W2053696072","https://openalex.org/W2055687876","https://openalex.org/W2077484102","https://openalex.org/W2089627656","https://openalex.org/W2102339709","https://openalex.org/W2113554746","https://openalex.org/W2116615213","https://openalex.org/W2123395438","https://openalex.org/W2161462657","https://openalex.org/W2172077519","https://openalex.org/W2271083698","https://openalex.org/W2302636722","https://openalex.org/W2306887830","https://openalex.org/W2310925774","https://openalex.org/W2342246138","https://openalex.org/W2408339495","https://openalex.org/W2417408054","https://openalex.org/W2419037363","https://openalex.org/W2467162260","https://openalex.org/W2516251801","https://openalex.org/W2526123185","https://openalex.org/W2527335053","https://openalex.org/W2566930261","https://openalex.org/W2605117891"],"related_works":["https://openalex.org/W7004981207","https://openalex.org/W2740338843","https://openalex.org/W2741220812","https://openalex.org/W2566080184","https://openalex.org/W2741786758","https://openalex.org/W2526123185","https://openalex.org/W1977636829","https://openalex.org/W2739648440","https://openalex.org/W2887209226","https://openalex.org/W2739902236"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2017-08-08T00:00:00"}