{"id":"https://openalex.org/W2738534387","doi":"https://doi.org/10.1038/nnano.2017.127","title":"A spatially localized architecture for fast and modular DNA computing","display_name":"A spatially localized architecture for fast and modular DNA computing","publication_year":2017,"publication_date":"2017-07-24","ids":{"openalex":"https://openalex.org/W2738534387","doi":"https://doi.org/10.1038/nnano.2017.127","mag":"2738534387","pmid":"https://pubmed.ncbi.nlm.nih.gov/28737747"},"language":"en","primary_location":{"id":"doi:10.1038/nnano.2017.127","doi":"https://doi.org/10.1038/nnano.2017.127","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nnano.2017.127","pdf_url":null,"source":{"id":"https://openalex.org/S7822423","display_name":"Nature Nanotechnology","issn_l":"1748-3387","issn":["1748-3387","1748-3395"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Nanotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2017/02/23/110965.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010852011","display_name":"Gourab Chatterjee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gourab Chatterjee","raw_affiliation_strings":["Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA","Department of Bioengineering, University of Washington, Seattle, 98195, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Bioengineering, University of Washington, Seattle, 98195, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005226523","display_name":"Neil Dalchau","orcid":"https://orcid.org/0000-0002-4872-6914","observed_orcids":["https://orcid.org/0000-0002-4872-6914"]},"institutions":[{"id":"https://openalex.org/I4210164937","display_name":"Microsoft Research (United Kingdom)","ror":"https://ror.org/05k87vq12","country_code":"GB","type":"company","lineage":["https://openalex.org/I1290206253","https://openalex.org/I4210164937"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Neil Dalchau","raw_affiliation_strings":["Microsoft Research, Cambridge, CB1 2FB, UK"],"raw_orcid":"https://orcid.org/0000-0002-4872-6914","affiliations":[{"raw_affiliation_string":"Microsoft Research, Cambridge, CB1 2FB, UK","institution_ids":["https://openalex.org/I4210164937"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024147185","display_name":"Richard A. Muscat","orcid":"https://orcid.org/0000-0003-1509-5674","observed_orcids":["https://orcid.org/0000-0003-1509-5674"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard A. Muscat","raw_affiliation_strings":["Department of Electrical Engineering, University of Washington, Seattle, Washington 98195, USA","Department of Electrical Engineering, University of Washington, Seattle, 98195, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of Washington, Seattle, Washington 98195, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Electrical Engineering, University of Washington, Seattle, 98195, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016397813","display_name":"Andrew Phillips","orcid":"https://orcid.org/0000-0001-9725-1073","observed_orcids":["https://orcid.org/0000-0001-9725-1073"]},"institutions":[{"id":"https://openalex.org/I4210164937","display_name":"Microsoft Research (United Kingdom)","ror":"https://ror.org/05k87vq12","country_code":"GB","type":"company","lineage":["https://openalex.org/I1290206253","https://openalex.org/I4210164937"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Andrew Phillips","raw_affiliation_strings":["Microsoft Research, Cambridge, CB1 2FB, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microsoft Research, Cambridge, CB1 2FB, UK","institution_ids":["https://openalex.org/I4210164937"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021731745","display_name":"Georg Seelig","orcid":"https://orcid.org/0000-0002-3163-8782","observed_orcids":["https://orcid.org/0000-0002-3163-8782"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Georg Seelig","raw_affiliation_strings":["Department of Electrical Engineering, University of Washington, Seattle, Washington 98195, USA","Paul G. Allen School of Computer Science &Engineering, University of Washington, Seattle, Washington 98195, USA","Department of Electrical Engineering, University of Washington, Seattle, 98195, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of Washington, Seattle, Washington 98195, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Paul G. Allen School of Computer Science &Engineering, University of Washington, Seattle, Washington 98195, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Electrical Engineering, University of Washington, Seattle, 98195, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5016397813","https://openalex.org/A5021731745"],"corresponding_institution_ids":["https://openalex.org/I201448701","https://openalex.org/I4210164937"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":34.791,"has_fulltext":false,"cited_by_count":360,"citation_normalized_percentile":{"value":0.9984326,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"12","issue":"9","first_page":"920","last_page":"927"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.6650000214576721,"subfield":{"id":"https://openalex.org/subfields/2614","display_name":"Theoretical Computer Science"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12029","display_name":"DNA and Biological Computing","score":0.6650000214576721,"subfield":{"id":"https://openalex.org/subfields/2614","display_name":"Theoretical Computer Science"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.3303000032901764,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-computing","display_name":"DNA computing","score":0.9729999899864197},{"id":"https://openalex.org/keywords/dna-origami","display_name":"DNA origami","score":0.8519999980926514},{"id":"https://openalex.org/keywords/spatial-organization","display_name":"spatial organization","score":0.7440000176429749},{"id":"https://openalex.org/keywords/logic-gates","display_name":"logic gates","score":0.734000027179718},{"id":"https://openalex.org/keywords/signal-transmission-lines","display_name":"signal transmission lines","score":0.9490000009536743},{"id":"https://openalex.org/keywords/dna-hairpin","display_name":"DNA hairpins","score":0.8519999980926514},{"id":"https://openalex.org/keywords/molecular-circuits","display_name":"molecular circuits","score":0.6259999871253967},{"id":"https://openalex.org/keywords/modular-circuit-design","display_name":"modular circuit design","score":0.6700000166893005},{"id":"https://openalex.org/keywords/colocalization","display_name":"colocalization","score":0.675000011920929},{"id":"https://openalex.org/keywords/reaction-kinetics","display_name":"reaction kinetics","score":0.640999972820282},{"id":"https://openalex.org/keywords/synthetic-biology","display_name":"synthetic biology","score":0.3440000116825104}],"concepts":[{"id":"https://openalex.org/C101468663","wikidata":"https://www.wikidata.org/wiki/Q1620158","display_name":"Modular design","level":2,"score":0.6739088296890259},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6688542366027832},{"id":"https://openalex.org/C134146338","wikidata":"https://www.wikidata.org/wiki/Q1815901","display_name":"Electronic circuit","level":2,"score":0.6263411045074463},{"id":"https://openalex.org/C131017901","wikidata":"https://www.wikidata.org/wiki/Q170451","display_name":"Logic gate","level":2,"score":0.5944769978523254},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.5662782788276672},{"id":"https://openalex.org/C82047324","wikidata":"https://www.wikidata.org/wiki/Q177126","display_name":"DNA computing","level":3,"score":0.549338161945343},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.5485393404960632},{"id":"https://openalex.org/C191908910","wikidata":"https://www.wikidata.org/wiki/Q862838","display_name":"Synthetic biology","level":2,"score":0.4456247091293335},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.34680891036987305},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3445679247379303},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3254772424697876},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.20689812302589417},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.18747466802597046},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.14434599876403809},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11731120944023132},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11462455987930298},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.09427627921104431},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D039301","descriptor_name":"Computers, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D053770","descriptor_name":"Nanowires","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/nnano.2017.127","doi":"https://doi.org/10.1038/nnano.2017.127","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nnano.2017.127","pdf_url":null,"source":{"id":"https://openalex.org/S7822423","display_name":"Nature Nanotechnology","issn_l":"1748-3387","issn":["1748-3387","1748-3395"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Nanotechnology","raw_type":"journal-article"},{"id":"doi:10.1101/110965","doi":"https://doi.org/10.1101/110965","is_oa":true,"landing_page_url":"https://doi.org/10.1101/110965","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2017/02/23/110965.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:28737747","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28737747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature nanotechnology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1101/110965","doi":"https://doi.org/10.1101/110965","is_oa":true,"landing_page_url":"https://doi.org/10.1101/110965","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2017/02/23/110965.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5508588265","display_name":null,"funder_award_id":"N00014-13-1-0880","funder_id":"https://openalex.org/F4320337345","funder_display_name":"Office of Naval Research"},{"id":"https://openalex.org/G6456018241","display_name":"HCC: Large: Collaborative Research: DNA Machine Builder: Creative molecular-machine design through mass-scale crowdsourcing","funder_award_id":"1212940","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8848415769","display_name":"SHF: Medium: DNA-based Molecular Architecture with Spatially Localized Components","funder_award_id":"1409831","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G8876996369","display_name":null,"funder_award_id":"N00014","funder_id":"https://openalex.org/F4320337345","funder_display_name":"Office of Naval Research"},{"id":"https://openalex.org/G8884853954","display_name":"Collaborative Research: Molecular Programming Architectures, Abstractions, Algorithms, and Applications","funder_award_id":"1317653","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320308943","display_name":"Microsoft Research","ror":"https://ror.org/00d0nc645"},{"id":"https://openalex.org/F4320337345","display_name":"Office of Naval Research","ror":"https://ror.org/00rk2pe57"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2738534387.pdf","grobid_xml":"https://content.openalex.org/works/W2738534387.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W140453663","https://openalex.org/W1617520624","https://openalex.org/W1829020990","https://openalex.org/W1829978875","https://openalex.org/W1964928696","https://openalex.org/W1976815031","https://openalex.org/W1986292487","https://openalex.org/W1989020100","https://openalex.org/W1989813275","https://openalex.org/W1990476699","https://openalex.org/W1993933078","https://openalex.org/W1999187172","https://openalex.org/W2000804241","https://openalex.org/W2005615084","https://openalex.org/W2019682748","https://openalex.org/W2032813700","https://openalex.org/W2041985017","https://openalex.org/W2042638652","https://openalex.org/W2063354556","https://openalex.org/W2066319051","https://openalex.org/W2075031385","https://openalex.org/W2078861258","https://openalex.org/W2082398508","https://openalex.org/W2082741569","https://openalex.org/W2092570226","https://openalex.org/W2096407632","https://openalex.org/W2102424174","https://openalex.org/W2109659042","https://openalex.org/W2109759968","https://openalex.org/W2126961173","https://openalex.org/W2127991158","https://openalex.org/W2128931425","https://openalex.org/W2147700328","https://openalex.org/W2148304424","https://openalex.org/W2150249752","https://openalex.org/W2151366879","https://openalex.org/W2151943426","https://openalex.org/W2158778875","https://openalex.org/W2186876778","https://openalex.org/W2210891699","https://openalex.org/W2213299895","https://openalex.org/W2272742955","https://openalex.org/W2307507937","https://openalex.org/W2318093937","https://openalex.org/W2322752065","https://openalex.org/W2330245166","https://openalex.org/W2331165568","https://openalex.org/W2344588994","https://openalex.org/W2418409341","https://openalex.org/W2464882657","https://openalex.org/W2484308666","https://openalex.org/W2500060530","https://openalex.org/W4239603118","https://openalex.org/W4251793802"],"related_works":["https://openalex.org/W2738762330","https://openalex.org/W3013276715","https://openalex.org/W2213299895","https://openalex.org/W7100895184","https://openalex.org/W7140089840","https://openalex.org/W2338469496","https://openalex.org/W2322752065","https://openalex.org/W2549905761","https://openalex.org/W2976321815","https://openalex.org/W1976086519"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":27},{"year":2025,"cited_by_count":35},{"year":2024,"cited_by_count":40},{"year":2023,"cited_by_count":44},{"year":2022,"cited_by_count":44},{"year":2021,"cited_by_count":48},{"year":2020,"cited_by_count":46},{"year":2019,"cited_by_count":31},{"year":2018,"cited_by_count":35},{"year":2017,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-07-31T00:00:00"}