{"id":"https://openalex.org/W2736714331","doi":"https://doi.org/10.1097/dss.0000000000001219","title":"Treatment of Facial Acne Scarring With Fractional Carbon Dioxide Laser in Asians, a Retrospective Analysis of Efficacy and Complications","display_name":"Treatment of Facial Acne Scarring With Fractional Carbon Dioxide Laser in Asians, a Retrospective Analysis of Efficacy and Complications","publication_year":2017,"publication_date":"2017-07-25","ids":{"openalex":"https://openalex.org/W2736714331","doi":"https://doi.org/10.1097/dss.0000000000001219","mag":"2736714331","pmid":"https://pubmed.ncbi.nlm.nih.gov/28746258"},"language":"en","primary_location":{"id":"doi:10.1097/dss.0000000000001219","doi":"https://doi.org/10.1097/dss.0000000000001219","is_oa":false,"landing_page_url":"https://doi.org/10.1097/dss.0000000000001219","pdf_url":null,"source":{"id":"https://openalex.org/S153994436","display_name":"Dermatologic Surgery","issn_l":"1076-0512","issn":["1076-0512","1524-4725"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatologic Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019564680","display_name":"Harumi Ochi","orcid":"https://orcid.org/0000-0001-7821-0591","observed_orcids":["https://orcid.org/0000-0001-7821-0591"]},"institutions":[{"id":"https://openalex.org/I1287551835","display_name":"National Skin Centre","ror":"https://ror.org/000p7hm12","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I1287551835"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Harumi Ochi","raw_affiliation_strings":["*All authors are affiliated with the National Skin Centre, Singapore","*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*All authors are affiliated with the National Skin Centre, Singapore","institution_ids":["https://openalex.org/I1287551835"]},{"raw_affiliation_string":"*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters","institution_ids":["https://openalex.org/I1287551835"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lixian Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287551835","display_name":"National Skin Centre","ror":"https://ror.org/000p7hm12","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I1287551835"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Lixian Tan","raw_affiliation_strings":["*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters","institution_ids":["https://openalex.org/I1287551835"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103720429","display_name":"Wee Ping Tan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287551835","display_name":"National Skin Centre","ror":"https://ror.org/000p7hm12","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I1287551835"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Wee Ping Tan","raw_affiliation_strings":["*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters","institution_ids":["https://openalex.org/I1287551835"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109198861","display_name":"Chee Leok Goh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287551835","display_name":"National Skin Centre","ror":"https://ror.org/000p7hm12","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I1287551835"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Chee Leok Goh","raw_affiliation_strings":["All authors are affiliated with the National Skin Centre, Singapore","*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"All authors are affiliated with the National Skin Centre, Singapore","institution_ids":["https://openalex.org/I1287551835"]},{"raw_affiliation_string":"*All authors are affiliated with the National Skin Centre, Singapore; The authors have indicated no significant interest with commercial supporters","institution_ids":["https://openalex.org/I1287551835"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5019564680"],"corresponding_institution_ids":["https://openalex.org/I1287551835"],"apc_list":null,"apc_paid":null,"fwci":3.3292,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.92008601,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"43","issue":"9","first_page":"1137","last_page":"1143"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11553","display_name":"Acne and Rosacea Treatments and Effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acne-scars","display_name":"acne scars","score":0.6869999766349792},{"id":"https://openalex.org/keywords/fractional-co2-laser","display_name":"fractional CO2 laser","score":0.8629999756813049},{"id":"https://openalex.org/keywords/laser-resurfacing","display_name":"laser resurfacing","score":0.8519999980926514},{"id":"https://openalex.org/keywords/asian-patients","display_name":"Asian patients","score":0.8019999861717224},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.9079999923706055},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.8360000252723694},{"id":"https://openalex.org/keywords/hyperpigmentation","display_name":"hyperpigmentation","score":0.9589999914169312},{"id":"https://openalex.org/keywords/fitzpatrick-skin-type","display_name":"Fitzpatrick skin type","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8815778493881226},{"id":"https://openalex.org/C2776728111","wikidata":"https://www.wikidata.org/wiki/Q1641068","display_name":"Hyperpigmentation","level":2,"score":0.7616155743598938},{"id":"https://openalex.org/C3020476846","wikidata":"https://www.wikidata.org/wiki/Q79928","display_name":"Acne scars","level":3,"score":0.7478049993515015},{"id":"https://openalex.org/C2776291823","wikidata":"https://www.wikidata.org/wiki/Q1291366","display_name":"Hypopigmentation","level":2,"score":0.7191710472106934},{"id":"https://openalex.org/C2777673923","wikidata":"https://www.wikidata.org/wiki/Q79928","display_name":"Acne","level":2,"score":0.6951854825019836},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.672920286655426},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6695982217788696},{"id":"https://openalex.org/C2777642821","wikidata":"https://www.wikidata.org/wiki/Q206060","display_name":"Scars","level":2,"score":0.647438645362854},{"id":"https://openalex.org/C2780902700","wikidata":"https://www.wikidata.org/wiki/Q1362150","display_name":"Carbon dioxide laser","level":4,"score":0.583853006362915},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5217400789260864},{"id":"https://openalex.org/C19617505","wikidata":"https://www.wikidata.org/wiki/Q156986","display_name":"Ablative case","level":3,"score":0.5037340521812439},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.43688833713531494},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2195209264755249},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.19686314463615417},{"id":"https://openalex.org/C2776829320","wikidata":"https://www.wikidata.org/wiki/Q847796","display_name":"Laser surgery","level":3,"score":0.09064507484436035},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000152","descriptor_name":"Acne Vulgaris","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D000152","descriptor_name":"Acne Vulgaris","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002921","descriptor_name":"Cicatrix","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D002921","descriptor_name":"Cicatrix","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002921","descriptor_name":"Cicatrix","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D005148","descriptor_name":"Facial Dermatoses","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D005148","descriptor_name":"Facial Dermatoses","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005148","descriptor_name":"Facial Dermatoses","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D054020","descriptor_name":"Lasers, Gas","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D054020","descriptor_name":"Lasers, Gas","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/dss.0000000000001219","doi":"https://doi.org/10.1097/dss.0000000000001219","is_oa":false,"landing_page_url":"https://doi.org/10.1097/dss.0000000000001219","pdf_url":null,"source":{"id":"https://openalex.org/S153994436","display_name":"Dermatologic Surgery","issn_l":"1076-0512","issn":["1076-0512","1524-4725"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatologic Surgery","raw_type":"journal-article"},{"id":"pmid:28746258","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28746258","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1541206612","https://openalex.org/W1879475197","https://openalex.org/W1996827809","https://openalex.org/W1998016764","https://openalex.org/W2015475934","https://openalex.org/W2028774729","https://openalex.org/W2029035724","https://openalex.org/W2032475639","https://openalex.org/W2049248298","https://openalex.org/W2056187974","https://openalex.org/W2058652767","https://openalex.org/W2068814162","https://openalex.org/W2074987109","https://openalex.org/W2085093981","https://openalex.org/W2091191911","https://openalex.org/W2105764547","https://openalex.org/W2107860845","https://openalex.org/W2111757015","https://openalex.org/W2113132585","https://openalex.org/W2114303820","https://openalex.org/W2123445626","https://openalex.org/W2153207157","https://openalex.org/W2157333569","https://openalex.org/W2159880866","https://openalex.org/W6683189600"],"related_works":["https://openalex.org/W2734009377","https://openalex.org/W2111757015","https://openalex.org/W4214583684","https://openalex.org/W4283761267","https://openalex.org/W3041512430","https://openalex.org/W2903132921","https://openalex.org/W2078130053","https://openalex.org/W2058652767","https://openalex.org/W4398187810","https://openalex.org/W2101099631"],"abstract_inverted_index":{"BACKGROUND:":[0],"Fractional":[1],"carbon":[2],"dioxide":[3],"(CO2)":[4],"laser":[5,40,58,79,127,196,268],"resurfacing":[6],"unites":[7],"the":[8,51,76,93,150,260,270],"idea":[9],"of":[10,23,45,55,71,105,108,114,154,172,186,201,264,272],"fractional":[11,56,77,125,266],"photothermolysis":[12],"with":[13,26,75],"an":[14],"ablative":[15],"10,600-nm":[16],"wavelength.":[17],"This":[18,66],"technology":[19],"permits":[20],"effective":[21],"treatment":[22,111,197,271,284],"acne":[24,60,82,131,174,273],"scarring,":[25,109],"shorter":[27],"recovery":[28],"and":[29,53,88,103,118,123,140,177,243,262,286],"a":[30,68,265],"decreased":[31],"side":[32,184],"effect":[33],"profile":[34],"as":[35],"compared":[36],"to":[37,49,147,223,237,281],"traditional":[38],"CO2":[39,57,78,126,267],"resurfacing.":[41],"OBJECTIVE:":[42],"The":[43,161,257],"aims":[44],"this":[46],"study":[47,50,70,151,258],"were":[48,133,181],"efficacy":[52,261],"safety":[54,263],"for":[59,80,129],"scars":[61,132,274],"in":[62,269,275],"Asian":[63],"patients.":[64],"METHODS:":[65],"was":[67],"retrospective":[69],"all":[72],"patients":[73,137,156,202],"treated":[74],"facial":[81,130],"scarring":[83,178],"between":[84],"January":[85],"2,":[86],"2008,":[87],"December":[89],"31,":[90],"2010,":[91],"at":[92],"National":[94],"Skin":[95],"Centre,":[96],"Singapore.":[97],"Data":[98],"reviewed":[99],"included":[100],"sex,":[101],"age,":[102],"severity":[104],"acne,":[106],"type":[107],"previous":[110],"history,":[112],"frequency":[113],"treatments,":[115],"adverse":[116,159,162],"events,":[117],"efficacy.":[119],"RESULTS:":[120],"Two":[121],"hundred":[122],"ten":[124],"treatments":[128],"performed":[134],"on":[135],"107":[136,155],"(65":[138],"men":[139],"42":[141],"women,":[142],"Fitzpatrick":[143],"skin":[144,206],"Types":[145],"II":[146],"V)":[148],"during":[149],"period.":[152],"Sixteen":[153],"experienced":[157],"(15.0%)":[158],"events.":[160],"events":[163],"include":[164],"hyperpigmentation":[165],"(6.4%),":[166],"blistering":[167],"(4.0%),":[168],"crusting":[169],"(2.9%),":[170],"aggravation":[171],"inflammatory":[173],"lesions":[175],"(1.7%),":[176],"(0.6%).":[179],"There":[180],"no":[182],"reported":[183,203],"effects":[185],"hypopigmentation,":[187],"bacterial":[188],"or":[189],"viral":[190],"infection.":[191],"Follow-up":[192],"results":[193],"after":[194],"final":[195],"showed":[198],"that":[199,209,220,234,249],"66.4%":[200],"Grade":[204,217,231,246],"1":[205],"texture":[207],"improvement,":[208,219,233,248],"is,":[210,221,235,250],"<25%":[211],"(n":[212,226,240,253],"=":[213,227,241,254],"71);":[214],"30.0%":[215],"had":[216,230,245],"2":[218],"25%":[222],"50%":[224],"improvement":[225,239,252],"31);":[228],"3.7%":[229],"3":[232],"51%":[236],"75%":[238],"4);":[242],"0.9%":[244],"4":[247],">75%":[251],"1).":[255],"CONCLUSION:":[256],"demonstrated":[259],"Asian.":[276],"Future":[277],"studies":[278],"are":[279],"required":[280],"establish":[282],"optimum":[283],"parameters":[285],"achieve":[287],"better":[288],"clinical":[289],"results.":[290]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-07-31T00:00:00"}