{"id":"https://openalex.org/W2736007375","doi":"https://doi.org/10.1161/str.47.suppl_1.74","title":"Abstract 74: An Update on Meta-analysis of Transcranial Direct Current Stimulation in Post-stroke Motor Recovery","display_name":"Abstract 74: An Update on Meta-analysis of Transcranial Direct Current Stimulation in Post-stroke Motor Recovery","publication_year":2016,"publication_date":"2016-02-01","ids":{"openalex":"https://openalex.org/W2736007375","doi":"https://doi.org/10.1161/str.47.suppl_1.74","mag":"2736007375"},"language":"en","primary_location":{"id":"doi:10.1161/str.47.suppl_1.74","doi":"https://doi.org/10.1161/str.47.suppl_1.74","is_oa":false,"landing_page_url":"https://doi.org/10.1161/str.47.suppl_1.74","pdf_url":null,"source":{"id":"https://openalex.org/S62532593","display_name":"Stroke","issn_l":"0039-2499","issn":["0039-2499","1524-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056603888","display_name":"Pratik Y. Chhatbar","orcid":"https://orcid.org/0000-0001-6436-8427","observed_orcids":["https://orcid.org/0000-0001-6436-8427"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pratik Y Chhatbar","raw_affiliation_strings":["Neurology, Med Univ of South Carolina, Charleston, SC","Pratik Y Chhatbar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology, Med Univ of South Carolina, Charleston, SC","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Pratik Y Chhatbar","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017840420","display_name":"Steven A. Kautz","orcid":"https://orcid.org/0000-0003-3151-8235","observed_orcids":["https://orcid.org/0000-0003-3151-8235"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven A Kautz","raw_affiliation_strings":["Dept of Health Sciences and Rsch, Med Univ of South Carolina, Charleston, SC","Steven A Kautz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Health Sciences and Rsch, Med Univ of South Carolina, Charleston, SC","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Steven A Kautz","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081593449","display_name":"Wuwei Feng","orcid":"https://orcid.org/0000-0001-6230-4905","observed_orcids":["https://orcid.org/0000-0001-6230-4905"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wuwei Feng","raw_affiliation_strings":["Neurology, Med Univ of South Carolina, Charleston, SC","Wuwei Feng"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology, Med Univ of South Carolina, Charleston, SC","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Wuwei Feng","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I153297377"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"47","issue":"suppl_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10510","display_name":"Stroke Rehabilitation and Recovery","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcranial-direct-current-stimulation","display_name":"transcranial direct current stimulation","score":1.0},{"id":"https://openalex.org/keywords/post-stroke-motor-recovery","display_name":"post-stroke motor recovery","score":0.9509999752044678},{"id":"https://openalex.org/keywords/stroke-rehabilitation","display_name":"stroke rehabilitation","score":0.5870000123977661},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.824999988079071},{"id":"https://openalex.org/keywords/chronic-stroke","display_name":"chronic stroke","score":0.828000009059906},{"id":"https://openalex.org/keywords/acute-stroke","display_name":"acute stroke","score":0.8930000066757202},{"id":"https://openalex.org/keywords/anodal-stimulation","display_name":"anodal stimulation","score":0.6990000009536743},{"id":"https://openalex.org/keywords/cathodal-stimulation","display_name":"cathodal stimulation","score":0.9269999861717224},{"id":"https://openalex.org/keywords/charge-density","display_name":"charge density","score":0.6340000033378601},{"id":"https://openalex.org/keywords/pad-size","display_name":"pad size","score":0.593999981880188}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8988468647003174},{"id":"https://openalex.org/C2777803708","wikidata":"https://www.wikidata.org/wiki/Q603398","display_name":"Transcranial direct-current stimulation","level":3,"score":0.7457330226898193},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.691311776638031},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.5994148254394531},{"id":"https://openalex.org/C99476002","wikidata":"https://www.wikidata.org/wiki/Q42297","display_name":"Analysis of variance","level":2,"score":0.4436437487602234},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4380094110965729},{"id":"https://openalex.org/C2776361831","wikidata":"https://www.wikidata.org/wiki/Q10681911","display_name":"Stroke recovery","level":3,"score":0.43120428919792175},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.39565786719322205},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37201160192489624},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3671882748603821},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.35325780510902405},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3180326521396637},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.07498306035995483},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/str.47.suppl_1.74","doi":"https://doi.org/10.1161/str.47.suppl_1.74","is_oa":false,"landing_page_url":"https://doi.org/10.1161/str.47.suppl_1.74","pdf_url":null,"source":{"id":"https://openalex.org/S62532593","display_name":"Stroke","issn_l":"0039-2499","issn":["0039-2499","1524-4628"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Stroke","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1451867453","https://openalex.org/W4406396113","https://openalex.org/W7161147746","https://openalex.org/W4220963530","https://openalex.org/W2988820558","https://openalex.org/W2747896045","https://openalex.org/W2947221069","https://openalex.org/W1845469431","https://openalex.org/W7065323996","https://openalex.org/W2043952966"],"abstract_inverted_index":{"Introduction:":[0],"Prior":[1],"meta-analyses":[2],"have":[3],"demonstrated":[4],"positive":[5,32],"summary":[6,89,192,216],"effect":[7,33,72,90,95],"of":[8,80],"tDCS":[9,37,63,159,270],"on":[10],"Fugl-Meyer":[11],"upper":[12],"extremity":[13],"scores":[14,235],"(FM-UE)":[15],"improvement":[16,274],"as":[17,19,74,84],"well":[18],"dose-response":[20,128],"relationship.":[21],"With":[22],"new":[23],"published":[24],"manuscripts,":[25],"we":[26],"are":[27],"not":[28],"sure":[29],"whether":[30],"this":[31],"still":[34],"holds.":[35],"Hypothesis:":[36],"leads":[38,271],"to":[39,48,272],"better":[40,162,255,273],"improvements":[41],"in":[42,51,181,275,283],"post-stroke":[43],"motor":[44,277],"recovery":[45],"when":[46],"compared":[47],"sham,":[49,281],"and":[50,115,247],"a":[52],"dose-dependent":[53],"manner.":[54],"Methods:":[55],"We":[56,70,87,103,135],"identified":[57,136],"sham-controlled,":[58],"randomized":[59],"studies":[60,138],"with":[61,122,139,149,178,183,207,238,249,280,285],"\u22655":[62],"sessions":[64],"from":[65],"PubMed":[66],"until":[67],"July":[68],"2015.":[69],"derived":[71],"size":[73,91,251],"standardized":[75],"mean":[76],"differences":[77],"(Hedge\u2019s":[78],"g)":[79],"change":[81,154,234],"scores,":[82],"defined":[83],"FM-UE":[85,153,233],"improvements.":[86],"calculated":[88],"by":[92],"using":[93],"random":[94],"model,":[96],"taking":[97],"any":[98],"data":[99],"heterogeneity":[100],"into":[101],"account.":[102],"plotted":[104],"current,":[105],"charge":[106,111,239],"(current":[107],"\u0445":[108,113],"duration),":[109],"total":[110],"(charge":[112],"sessions)":[114],"their":[116],"density":[117,240],"counterparts":[118],"(by":[119],"dividing":[120],"each":[121],"pad":[123,250],"size).":[124],"To":[125],"assess":[126],"the":[127,253,256],"relationship,":[129],"inverse-variance-based":[130],"meta-regression":[131],"was":[132],"performed.":[133],"Results:":[134],"9":[137],"234":[140],"subjects":[141],"comparing":[142],"active":[143],"stimulation":[144,151],"(anodal,":[145],"cathodal":[146],"or":[147],"bihemispheric)":[148],"sham":[150,164],"against":[152],"scores.":[155],"Stroke":[156],"patients":[157,182,284],"receiving":[158],"improved":[160],"significantly":[161],"than":[163,205,279],"(summary":[165],"Hedge\u2019s":[166,193,217],"g":[167,194,218],"=":[168,172,176,195,199,203,219,223,227,242,245,259,262],"0.65,":[169],"95%":[170,197,221],"CI":[171,198,222],"[0.18,":[173],"1.13],":[174],"p":[175,202,226,244,261],"0.03),":[177],"superior":[179],"results":[180],"chronic":[184,286],"stroke":[185,189,209,213],"(average":[186,210],"time":[187,211],"since":[188,212],">2":[190],"years,":[191],"1.11,":[196],"[0.43,":[200],"1.83],":[201],"0.001)":[204],"those":[206],"acute":[208],"<2":[214],"months,":[215],"0.18,":[220],"[-0.30,":[224],"0.66],":[225],"0.47).":[228],"Dose-response":[229],"relationship":[230],"showed":[231],"that":[232,269],"correlated":[236],"positively":[237],"(R2":[241],"0.20,":[243],"0.036)":[246],"negatively":[248],"(smaller":[252],"pad,":[254],"effect;":[257],"R2":[258],"0.58,":[260],"0.002).":[263],"Conclusion:":[264],"This":[265],"updated":[266],"meta-analysis":[267],"supports":[268],"UE":[276],"outcome":[278],"especially":[282],"stroke.":[287]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2017-07-21T00:00:00"}