{"id":"https://openalex.org/W2735912187","doi":"https://doi.org/10.21103/article4_3_r1","title":"Metabolic Consequences of Skeletal Muscle Atrophy Caused by Space Flight Conditions","display_name":"Metabolic Consequences of Skeletal Muscle Atrophy Caused by Space Flight Conditions","publication_year":2014,"publication_date":"2014-09-20","ids":{"openalex":"https://openalex.org/W2735912187","doi":"https://doi.org/10.21103/article4_3_r1","mag":"2735912187"},"language":"en","primary_location":{"id":"doi:10.21103/article4_3_r1","doi":"https://doi.org/10.21103/article4_3_r1","is_oa":true,"landing_page_url":"https://doi.org/10.21103/article4_3_r1","pdf_url":"https://doi.org/10.21103/article4_3_r1","source":{"id":"https://openalex.org/S2736370905","display_name":"International Journal of Biomedicine","issn_l":"2158-0510","issn":["2158-0510","2158-0529"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["erih-plus","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310315865","host_organization_name":"International Medical Research and Development Corporation","host_organization_lineage":["https://openalex.org/P4310315865"],"host_organization_lineage_names":["International Medical Research and Development Corporation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biomedicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.21103/article4_3_r1","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Irina Larina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210101246","display_name":"Institute of Biomedical Problems","ror":"https://ror.org/016hfp155","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210101246","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Irina Larina","raw_affiliation_strings":["\u00b9SSC RF Institute of Biomedical Problems of RAS \u00b2I.M. Sechenov First Moscow State Medical University Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00b9SSC RF Institute of Biomedical Problems of RAS \u00b2I.M. Sechenov First Moscow State Medical University Moscow, Russian Federation","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210101246"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Moscow, Russian Federation","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210101246","display_name":"Institute of Biomedical Problems","ror":"https://ror.org/016hfp155","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210101246","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Moscow, Russian Federation","raw_affiliation_strings":["\u00b9SSC RF Institute of Biomedical Problems of RAS \u00b2I.M. Sechenov First Moscow State Medical University Moscow, Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00b9SSC RF Institute of Biomedical Problems of RAS \u00b2I.M. Sechenov First Moscow State Medical University Moscow, Russian Federation","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210101246"]}]},{"author_position":"last","author":{"id":null,"display_name":"Irina Ogneva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17877952","display_name":"Sechenov University","ror":"https://ror.org/02yqqv993","country_code":"RU","type":"education","lineage":["https://openalex.org/I17877952"]},{"id":"https://openalex.org/I4210101246","display_name":"Institute of Biomedical Problems","ror":"https://ror.org/016hfp155","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210101246","https://openalex.org/I4210115279"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Irina Ogneva","raw_affiliation_strings":["\u00b9SSC RF Institute of Biomedical Problems of RAS \u00b2I.M. Sechenov First Moscow State Medical University Moscow , Russian Federation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00b9SSC RF Institute of Biomedical Problems of RAS \u00b2I.M. Sechenov First Moscow State Medical University Moscow , Russian Federation","institution_ids":["https://openalex.org/I17877952","https://openalex.org/I4210101246"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":400,"currency":"USD","value_usd":400},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36272871,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"3","first_page":"129","last_page":"137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/skeletal-muscle-atrophy","display_name":"skeletal muscle atrophy","score":0.9739999771118164},{"id":"https://openalex.org/keywords/spaceflight","display_name":"spaceflight","score":0.8479999899864197},{"id":"https://openalex.org/keywords/microgravity","display_name":"microgravity","score":0.800000011920929},{"id":"https://openalex.org/keywords/muscle-metabolism","display_name":"muscle metabolism","score":0.8690000176429749},{"id":"https://openalex.org/keywords/gluconeogenesis","display_name":"gluconeogenesis","score":0.7799999713897705},{"id":"https://openalex.org/keywords/myocardial-oxygen-consumption","display_name":"myocardial oxygen consumption","score":0.8220000267028809},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.7329999804496765},{"id":"https://openalex.org/keywords/liver-metabolism","display_name":"hepatic metabolism","score":0.7279999852180481},{"id":"https://openalex.org/keywords/postural-muscles","display_name":"postural muscles","score":0.7860000133514404}],"concepts":[{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.6472523212432861},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.6411420106887817},{"id":"https://openalex.org/C20904676","wikidata":"https://www.wikidata.org/wiki/Q191835","display_name":"Gluconeogenesis","level":3,"score":0.4938145577907562},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4895966649055481},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4875287711620331},{"id":"https://openalex.org/C2776263037","wikidata":"https://www.wikidata.org/wiki/Q1557686","display_name":"Muscle atrophy","level":3,"score":0.4648410677909851},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.41790771484375},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37936604022979736},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22297927737236023}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.21103/article4_3_r1","doi":"https://doi.org/10.21103/article4_3_r1","is_oa":true,"landing_page_url":"https://doi.org/10.21103/article4_3_r1","pdf_url":"https://doi.org/10.21103/article4_3_r1","source":{"id":"https://openalex.org/S2736370905","display_name":"International Journal of Biomedicine","issn_l":"2158-0510","issn":["2158-0510","2158-0529"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["erih-plus","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310315865","host_organization_name":"International Medical Research and Development Corporation","host_organization_lineage":["https://openalex.org/P4310315865"],"host_organization_lineage_names":["International Medical Research and Development Corporation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biomedicine","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:71e509d19c3042ea952f436ffad047af","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/71e509d19c3042ea952f436ffad047af","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Biomedicine, Vol 4, Iss 3, Pp 129-137 (2014)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.21103/article4_3_r1","doi":"https://doi.org/10.21103/article4_3_r1","is_oa":true,"landing_page_url":"https://doi.org/10.21103/article4_3_r1","pdf_url":"https://doi.org/10.21103/article4_3_r1","source":{"id":"https://openalex.org/S2736370905","display_name":"International Journal of Biomedicine","issn_l":"2158-0510","issn":["2158-0510","2158-0529"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["erih-plus","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310315865","host_organization_name":"International Medical Research and Development Corporation","host_organization_lineage":["https://openalex.org/P4310315865"],"host_organization_lineage_names":["International Medical Research and Development Corporation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biomedicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2735912187.pdf","grobid_xml":"https://content.openalex.org/works/W2735912187.grobid-xml"},"referenced_works_count":90,"referenced_works":["https://openalex.org/W51805046","https://openalex.org/W51947104","https://openalex.org/W107017769","https://openalex.org/W118965087","https://openalex.org/W148403024","https://openalex.org/W196896886","https://openalex.org/W233973022","https://openalex.org/W1495603145","https://openalex.org/W1535384676","https://openalex.org/W1549689418","https://openalex.org/W1592368907","https://openalex.org/W1599204041","https://openalex.org/W1606896721","https://openalex.org/W1755781900","https://openalex.org/W1763668807","https://openalex.org/W1804963346","https://openalex.org/W1821801397","https://openalex.org/W1831670779","https://openalex.org/W1843900867","https://openalex.org/W1880875467","https://openalex.org/W1888556760","https://openalex.org/W1894537211","https://openalex.org/W1944638604","https://openalex.org/W1944655445","https://openalex.org/W1944892980","https://openalex.org/W1944916001","https://openalex.org/W1972688251","https://openalex.org/W1982479833","https://openalex.org/W1984121364","https://openalex.org/W1987137066","https://openalex.org/W1990401509","https://openalex.org/W1993646647","https://openalex.org/W1995336211","https://openalex.org/W2003260329","https://openalex.org/W2005517963","https://openalex.org/W2008961486","https://openalex.org/W2016285706","https://openalex.org/W2020356527","https://openalex.org/W2030895815","https://openalex.org/W2044726034","https://openalex.org/W2049730501","https://openalex.org/W2051153740","https://openalex.org/W2056135938","https://openalex.org/W2063108329","https://openalex.org/W2069180529","https://openalex.org/W2094294340","https://openalex.org/W2104591591","https://openalex.org/W2112294135","https://openalex.org/W2112694892","https://openalex.org/W2117953090","https://openalex.org/W2118532242","https://openalex.org/W2120567798","https://openalex.org/W2121137172","https://openalex.org/W2123068470","https://openalex.org/W2129573469","https://openalex.org/W2129898693","https://openalex.org/W2139015983","https://openalex.org/W2139656274","https://openalex.org/W2143099870","https://openalex.org/W2148980400","https://openalex.org/W2170299698","https://openalex.org/W2175290961","https://openalex.org/W2182534139","https://openalex.org/W2199402133","https://openalex.org/W2219705225","https://openalex.org/W2222343215","https://openalex.org/W2227857135","https://openalex.org/W2253040085","https://openalex.org/W2259562088","https://openalex.org/W2270230062","https://openalex.org/W2301668395","https://openalex.org/W2396772859","https://openalex.org/W2399347134","https://openalex.org/W2406748704","https://openalex.org/W2406784412","https://openalex.org/W2407452734","https://openalex.org/W2410434646","https://openalex.org/W2419121063","https://openalex.org/W2426217090","https://openalex.org/W2435302292","https://openalex.org/W2439100886","https://openalex.org/W2439212691","https://openalex.org/W2442756888","https://openalex.org/W2443398167","https://openalex.org/W2462681769","https://openalex.org/W2470931041","https://openalex.org/W2582446141","https://openalex.org/W2993826357","https://openalex.org/W2994077365","https://openalex.org/W4242948373"],"related_works":["https://openalex.org/W4226377177","https://openalex.org/W4296935039","https://openalex.org/W1944638604","https://openalex.org/W1983855830","https://openalex.org/W11306949","https://openalex.org/W2116440960","https://openalex.org/W6991146945","https://openalex.org/W2468590156","https://openalex.org/W2009500072","https://openalex.org/W1544179795"],"abstract_inverted_index":{"The":[0],"review":[1],"aims":[2],"to":[3,54],"analyze":[4],"the":[5,23,28,45,52,56,61,67,70,74],"relationship":[6],"between":[7],"metabolic":[8],"changes":[9],"in":[10,14,34,60],"muscle":[11,76],"tissue":[12],"occurring":[13],"space":[15],"flight":[16],"conditions":[17],"and":[18,37,66],"other":[19],"body":[20],"systems":[21,33],"during":[22,44],"developing":[24],"atrophy.The":[25],"data":[26],"about":[27],"activity":[29,57],"of":[30,47,58,69],"various":[31],"enzyme":[32],"muscles,":[35,49],"liver":[36,62],"myocardium":[38],"are":[39],"presented.It":[40],"was":[41],"shown":[42],"that":[43],"transformation":[46],"postural":[48],"metabolism":[50],"from":[51],"lipid":[53],"carbohydrate,":[55],"gluconeogenesis":[59],"pathways":[63],"is":[64],"increased":[65],"intensity":[68],"oxygen":[71],"consumption":[72],"by":[73],"heart":[75],"changes.":[77]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-07-21T00:00:00"}
