{"id":"https://openalex.org/W27357950","doi":null,"title":"Psychiatric perspectives of brain, behavior, and the immune system.","display_name":"Psychiatric perspectives of brain, behavior, and the immune system.","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W27357950","mag":"27357950","pmid":"https://pubmed.ncbi.nlm.nih.gov/2183309"},"language":"en","primary_location":{"id":"pmid:2183309","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2183309","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research publications - Association for Research in Nervous and Mental Disease","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102079745","display_name":"Marvin Stein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Stein","raw_affiliation_strings":["Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029-6574"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029-6574","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112103427","display_name":"R L Trestman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R L Trestman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2363,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.77094972,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"68","issue":null,"first_page":"161","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.029899999499320984,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroimmunology","display_name":"neuroimmunology","score":0.7889999747276306},{"id":"https://openalex.org/keywords/mental-disorders","display_name":"mental illness","score":0.7059999704360962},{"id":"https://openalex.org/keywords/stress","display_name":"stress","score":0.6460000276565552},{"id":"https://openalex.org/keywords/immune-system-alterations","display_name":"immune system alterations","score":0.8100000023841858},{"id":"https://openalex.org/keywords/brain-behavior-relationship","display_name":"brain-behavior relationship","score":0.6840000152587891},{"id":"https://openalex.org/keywords/neurobiology-of-behavior","display_name":"neurobiology of behavior","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7669947147369385},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5912047624588013},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4512733817100525},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36324799060821533},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3289772868156433},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3287665843963623}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001519","descriptor_name":"Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004198","descriptor_name":"Disease Susceptibility","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D007121","descriptor_name":"Immunocompetence","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019965","descriptor_name":"Neurocognitive Disorders","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:2183309","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2183309","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research publications - Association for Research in Nervous and Mental Disease","raw_type":"Journal Article"},{"id":"mag:27357950","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2183309","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W198738073","https://openalex.org/W1509805561","https://openalex.org/W1530962156","https://openalex.org/W1602232839","https://openalex.org/W1968678717","https://openalex.org/W1978556098","https://openalex.org/W1980872419","https://openalex.org/W1982652659","https://openalex.org/W1989673745","https://openalex.org/W1991592722","https://openalex.org/W2008126319","https://openalex.org/W2009100605","https://openalex.org/W2010276640","https://openalex.org/W2010732063","https://openalex.org/W2011675522","https://openalex.org/W2011963516","https://openalex.org/W2026761773","https://openalex.org/W2033381628","https://openalex.org/W2037548392","https://openalex.org/W2049694903","https://openalex.org/W2054794305","https://openalex.org/W2058641914","https://openalex.org/W2063266714","https://openalex.org/W2063624770","https://openalex.org/W2064488040","https://openalex.org/W2066367755","https://openalex.org/W2073082953","https://openalex.org/W2078730195","https://openalex.org/W2081394289","https://openalex.org/W2089041648","https://openalex.org/W2090280224","https://openalex.org/W2097092679","https://openalex.org/W2104096646","https://openalex.org/W2108285596","https://openalex.org/W2110147097","https://openalex.org/W2113125059","https://openalex.org/W2114280746","https://openalex.org/W2114798850","https://openalex.org/W2115871167","https://openalex.org/W2118676803","https://openalex.org/W2119018344","https://openalex.org/W2121893446","https://openalex.org/W2127400843","https://openalex.org/W2131018161","https://openalex.org/W2134308182","https://openalex.org/W2142264345","https://openalex.org/W2147783879","https://openalex.org/W2150642389","https://openalex.org/W2151880115","https://openalex.org/W2153940455","https://openalex.org/W2161575454","https://openalex.org/W2166383881","https://openalex.org/W2166817188","https://openalex.org/W2170699361","https://openalex.org/W2172008520","https://openalex.org/W2175825977","https://openalex.org/W2187969653","https://openalex.org/W2213926659","https://openalex.org/W2216971129","https://openalex.org/W2277786607","https://openalex.org/W2363034775","https://openalex.org/W2397761552","https://openalex.org/W2502918978"],"related_works":["https://openalex.org/W1986883807","https://openalex.org/W2425586985","https://openalex.org/W2130209951","https://openalex.org/W162225099","https://openalex.org/W7161041934","https://openalex.org/W154999198","https://openalex.org/W171252941","https://openalex.org/W2035317071","https://openalex.org/W4241586625","https://openalex.org/W4233092620"],"abstract_inverted_index":{"There":[0],"is":[1,24,45],"increasing":[2],"evidence":[3,47],"of":[4,11,34,56,73,77,80,83],"reciprocal":[5],"CNS-immune":[6],"system":[7,37,89],"interactions.":[8],"The":[9],"reaction":[10],"such":[12],"processes":[13],"to":[14,20],"behavior":[15],"and":[16,66,69,86],"psychiatric":[17,57],"disorders":[18],"remains":[19],"be":[21,91],"determined.":[22],"It":[23],"not":[25],"clear":[26],"at":[27],"this":[28],"time":[29],"if":[30],"alterations":[31,50],"in":[32,63],"measures":[33],"the":[35,54,60,71,81,87],"immune":[36,49,88],"associated":[38,52],"with":[39,53,70],"stress":[40],"have":[41],"clinical":[42],"relevance,":[43],"nor":[44],"there":[46],"that":[48],"are":[51],"pathogenesis":[55],"disorders.":[58],"With":[59],"exciting":[61],"advances":[62],"neurobiology,":[64],"immunobiology,":[65],"biologic":[67],"psychiatry,":[68],"availability":[72],"a":[74],"wide":[75],"range":[76],"methodologies,":[78],"elucidation":[79],"complexities":[82],"brain,":[84],"behavior,":[85],"may":[90],"achieved.":[92]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
