{"id":"https://openalex.org/W2734849012","doi":"https://doi.org/10.1089/neu.2017.5046","title":"Prospective Assessment of Acute Blood Markers of Brain Injury in Sport-Related Concussion","display_name":"Prospective Assessment of Acute Blood Markers of Brain Injury in Sport-Related Concussion","publication_year":2017,"publication_date":"2017-07-12","ids":{"openalex":"https://openalex.org/W2734849012","doi":"https://doi.org/10.1089/neu.2017.5046","mag":"2734849012","pmid":"https://pubmed.ncbi.nlm.nih.gov/28699381","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5678359"},"language":"en","primary_location":{"id":"doi:10.1089/neu.2017.5046","doi":"https://doi.org/10.1089/neu.2017.5046","is_oa":false,"landing_page_url":"https://doi.org/10.1089/neu.2017.5046","pdf_url":null,"source":{"id":"https://openalex.org/S85864898","display_name":"Journal of Neurotrauma","issn_l":"0897-7151","issn":["0897-7151","1557-9042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurotrauma","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC5678359","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059402802","display_name":"Timothy Bradley Meier","orcid":"https://orcid.org/0000-0002-4495-2754","observed_orcids":["https://orcid.org/0000-0002-4495-2754"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Timothy B. Meier","raw_affiliation_strings":["Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin","Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]},{"raw_affiliation_string":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006040237","display_name":"Lindsay D. Nelson","orcid":"https://orcid.org/0000-0001-5258-953X","observed_orcids":["https://orcid.org/0000-0001-5258-953X"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lindsay D. Nelson","raw_affiliation_strings":["Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin","Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]},{"raw_affiliation_string":"Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055444544","display_name":"Daniel L. Huber","orcid":"https://orcid.org/0000-0003-2079-0647","observed_orcids":["https://orcid.org/0000-0003-2079-0647"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel L. Huber","raw_affiliation_strings":["Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059401509","display_name":"Jeffrey J. Bazarian","orcid":"https://orcid.org/0000-0001-7100-3805","observed_orcids":["https://orcid.org/0000-0001-7100-3805"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey J. Bazarian","raw_affiliation_strings":["Department of Emergency Medicine, University of Rochester School of Medicine, Rochester, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, University of Rochester School of Medicine, Rochester, New York","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108440222","display_name":"Ronald L. Hayes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154627","display_name":"Banyan Biomarkers (United States)","ror":"https://ror.org/04cq3yd71","country_code":"US","type":"company","lineage":["https://openalex.org/I4210154627"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald L. Hayes","raw_affiliation_strings":["Banyan Labs, Banyan Biomarkers Inc., Alachua, Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banyan Labs, Banyan Biomarkers Inc., Alachua, Florida","institution_ids":["https://openalex.org/I4210154627"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018437283","display_name":"Michael McCrea","orcid":"https://orcid.org/0000-0001-9791-9475","observed_orcids":["https://orcid.org/0000-0001-9791-9475"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael A. McCrea","raw_affiliation_strings":["Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin","Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]},{"raw_affiliation_string":"Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin","institution_ids":["https://openalex.org/I204308271"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5059402802"],"corresponding_institution_ids":["https://openalex.org/I204308271"],"apc_list":null,"apc_paid":null,"fwci":6.6369,"has_fulltext":false,"cited_by_count":78,"citation_normalized_percentile":{"value":0.97628752,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"34","issue":"22","first_page":"3134","last_page":"3142"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11246","display_name":"Sports injuries and prevention","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sports-related-concussion","display_name":"sports-related concussion","score":0.9980000257492065},{"id":"https://openalex.org/keywords/blood-biomarkers","display_name":"blood biomarkers","score":0.9039999842643738},{"id":"https://openalex.org/keywords/s100b","display_name":"S100B","score":0.9139999747276306},{"id":"https://openalex.org/keywords/uchl1","display_name":"UCHL1","score":0.9089999794960022},{"id":"https://openalex.org/keywords/glial-fibrillary-acidic-protein","display_name":"glial fibrillary acidic protein","score":0.902999997138977},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.6539999842643738},{"id":"https://openalex.org/keywords/football-players","display_name":"football players","score":0.7390000224113464},{"id":"https://openalex.org/keywords/acute-concussion","display_name":"acute concussion","score":0.4970000088214874},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C2778426673","wikidata":"https://www.wikidata.org/wiki/Q326921","display_name":"Concussion","level":4,"score":0.9096082448959351},{"id":"https://openalex.org/C2781054738","wikidata":"https://www.wikidata.org/wiki/Q4813730","display_name":"Athletes","level":2,"score":0.7473522424697876},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6649798154830933},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.502194881439209},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.4614710807800293},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.4564899802207947},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.4383939802646637},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.4058932065963745},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.36875951290130615},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3685232996940613},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.15140211582183838},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07165423035621643}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001265","descriptor_name":"Athletic Injuries","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001924","descriptor_name":"Brain Concussion","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005538","descriptor_name":"Football","qualifier_ui":"Q000293","qualifier_name":"injuries","is_major_topic":true},{"descriptor_ui":"D005904","descriptor_name":"Glial Fibrillary Acidic Protein","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D043222","descriptor_name":"Ubiquitin Thiolesterase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064568","descriptor_name":"S100 Calcium Binding Protein beta Subunit","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1089/neu.2017.5046","doi":"https://doi.org/10.1089/neu.2017.5046","is_oa":false,"landing_page_url":"https://doi.org/10.1089/neu.2017.5046","pdf_url":null,"source":{"id":"https://openalex.org/S85864898","display_name":"Journal of Neurotrauma","issn_l":"0897-7151","issn":["0897-7151","1557-9042"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurotrauma","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5178986","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5678359","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5678359","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5678359","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Neurotrauma","raw_type":"Text"},{"id":"pmid:28699381","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28699381","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurotrauma","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5178986","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC5678359","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4119534169","display_name":null,"funder_award_id":"W81XWH","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G5850682332","display_name":null,"funder_award_id":"W81XWH","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G724264902","display_name":"Clincal and Translational Science Award","funder_award_id":"UL1TR000055","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W27664858","https://openalex.org/W1640041938","https://openalex.org/W1742108937","https://openalex.org/W1782823499","https://openalex.org/W1899517240","https://openalex.org/W1973604810","https://openalex.org/W1999684482","https://openalex.org/W2004928040","https://openalex.org/W2012066635","https://openalex.org/W2032220418","https://openalex.org/W2033297074","https://openalex.org/W2035369214","https://openalex.org/W2039885178","https://openalex.org/W2048301270","https://openalex.org/W2050073457","https://openalex.org/W2054047969","https://openalex.org/W2058131087","https://openalex.org/W2062219794","https://openalex.org/W2064335645","https://openalex.org/W2065167286","https://openalex.org/W2066034215","https://openalex.org/W2067975546","https://openalex.org/W2074690949","https://openalex.org/W2080601011","https://openalex.org/W2109716894","https://openalex.org/W2110065044","https://openalex.org/W2110913939","https://openalex.org/W2116075855","https://openalex.org/W2127170862","https://openalex.org/W2197374699","https://openalex.org/W2217032034","https://openalex.org/W2286535726","https://openalex.org/W2294343212","https://openalex.org/W2327228538","https://openalex.org/W2461067695","https://openalex.org/W2466729373","https://openalex.org/W2483730030","https://openalex.org/W2584736474","https://openalex.org/W3025159797","https://openalex.org/W3034829831","https://openalex.org/W3094721569","https://openalex.org/W4234801520"],"related_works":["https://openalex.org/W3002727969","https://openalex.org/W4289955927","https://openalex.org/W3013662321","https://openalex.org/W7203502891","https://openalex.org/W4410951571","https://openalex.org/W7166694987","https://openalex.org/W2066034215","https://openalex.org/W2978149154","https://openalex.org/W3004663670","https://openalex.org/W4410951555"],"abstract_inverted_index":{"There":[0],"is":[1],"a":[2],"pressing":[3],"need":[4],"to":[5,16,36,144,174,227,254],"identify":[6],"objective":[7],"biomarkers":[8,291],"for":[9,23,282,289],"the":[10,18,24,32,39,139,272,280,286,293],"assessment":[11],"of":[12,26,31,42,47,219,261,267,296],"sport-related":[13],"concussion":[14],"(SRC)":[15],"reduce":[17],"reliance":[19],"on":[20,44],"clinical":[21,287],"judgment":[22],"management":[25],"these":[27],"injuries.":[28],"The":[29,108],"goal":[30],"current":[33],"study":[34,257],"was":[35,116],"prospectively":[37],"establish":[38],"acute":[40,274],"effects":[41],"SRC":[43,89],"serum":[45,265],"levels":[46,137,146,154,243,266],"S100":[48],"calcium-binding":[49],"protein":[50,56],"beta":[51],"(S100B),":[52],"glial":[53],"fibrillary":[54],"acidic":[55],"(GFAP),":[57],"and":[58,64,71,84,101,113,122,153,182,197,221,237,269,278],"ubiquitin":[59],"C-terminal":[60],"hydrolase-L1":[61],"(UCH-L1).":[62],"Collegiate":[63],"high":[65],"school":[66],"football":[67,94],"players":[68,95],"were":[69],"enrolled":[70],"provided":[72],"blood":[73,114],"at":[74,82,138,170,223],"pre-season.":[75,255],"Injured":[76],"athletes":[77,132,157,165,199,252],"participated":[78,96],"in":[79,97,128,155,250,264,292],"follow-up":[80,99],"visits":[81,100],"\u223c6":[83],"24-48":[85],"h":[86,118,120,124,126,141,172,225],"following":[87,276],"documented":[88],"(n":[90,105],"=":[91,106,148,151,159,162,177,180,185,188,210,215,234,239],"32).":[92],"Uninjured":[93],"similar":[98],"served":[102],"as":[103],"controls":[104,183],"29).":[107],"median":[109],"time":[110],"between":[111,195,247],"injury":[112],"collection":[115],"2":[117],"(6":[119],"visit)":[121,127],"22.5":[123],"(24-48":[125],"concussed":[129,196,251],"athletes.":[130],"Concussed":[131,164],"had":[133,167],"significantly":[134],"elevated":[135,168],"UCH-L1":[136,220,268],"6":[140,171,224],"visit":[142],"relative":[143,173,226,253],"pre-season":[145,175,228],"(Z":[147,158,176,184],"2.22,":[149],"p":[150,161,179,187],"0.03)":[152],"control":[156,198],"3.02,":[160],"0.003).":[163],"also":[166,229],"S100B":[169,213,222,270],"2.07,":[178],"0.04)":[181],"2.75,":[186],"0.006).":[189],"Both":[190],"markers":[191],"showed":[192,230],"fair":[193,231],"discrimination":[194,232],"(UCH-L1":[200],"area":[201],"under":[202],"receiver":[203],"operating":[204],"characteristic":[205],"curve":[206],"[AUC]":[207],"[95%":[208],"CI]":[209],"0.74":[211],"[0.61-0.88],":[212],"AUC":[214,238],"0.72":[216],"[0.58-0.87]).":[217],"Percent-change":[218],"(AUC":[233],"0.79":[235],"[0.66-0.92]":[236],"0.77":[240],"[0.64-0.90]).":[241],"GFAP":[242],"did":[244],"not":[245],"differ":[246],"groups":[248],"or":[249],"This":[256],"provides":[258],"prospective":[259],"evidence":[260],"significant":[262],"increases":[263],"during":[271],"early":[273,294],"period":[275],"SRC,":[277],"lays":[279],"foundation":[281],"future":[283],"studies":[284],"examining":[285],"potential":[288],"blood-based":[290],"detection":[295],"concussion.":[297]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":10}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-07-21T00:00:00"}