{"id":"https://openalex.org/W2731329638","doi":"https://doi.org/10.1097/yco.0000000000000350","title":"Depressed gut? The microbiota-diet-inflammation trialogue in depression","display_name":"Depressed gut? The microbiota-diet-inflammation trialogue in depression","publication_year":2017,"publication_date":"2017-06-27","ids":{"openalex":"https://openalex.org/W2731329638","doi":"https://doi.org/10.1097/yco.0000000000000350","mag":"2731329638","pmid":"https://pubmed.ncbi.nlm.nih.gov/28654462"},"language":"en","primary_location":{"id":"doi:10.1097/yco.0000000000000350","doi":"https://doi.org/10.1097/yco.0000000000000350","is_oa":false,"landing_page_url":"https://doi.org/10.1097/yco.0000000000000350","pdf_url":null,"source":{"id":"https://openalex.org/S15258550","display_name":"Current Opinion in Psychiatry","issn_l":"0951-7367","issn":["0951-7367","1473-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Psychiatry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://research.rug.nl/en/publications/dc4649cf-90be-4f43-96b3-f05be9e29d81","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035924397","display_name":"Margreet B. Koopman","orcid":"https://orcid.org/0000-0001-6100-4898","observed_orcids":["https://orcid.org/0000-0001-6100-4898"]},"institutions":[{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]},{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]},{"id":"https://openalex.org/I4210116302","display_name":"Asklepios Fachklinikum Tiefenbrunn","ror":"https://ror.org/01m5mwt22","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210116302"]}],"countries":["AT","DE","NL"],"is_corresponding":false,"raw_author_name":"Margreet Koopman","raw_affiliation_strings":["aMicrobial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands bJudith K Daniels; Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, The Netherlands cCarsten Spitzer, Asklepios Fachklinikum Tiefenbrunn, Gottingen, Germany dAstrid Lampe, Department Psychiatry and Psychotherapy, University of Innsbruck, Austria","Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"aMicrobial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands bJudith K Daniels; Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, The Netherlands cCarsten Spitzer, Asklepios Fachklinikum Tiefenbrunn, Gottingen, Germany dAstrid Lampe, Department Psychiatry and Psychotherapy, University of Innsbruck, Austria","institution_ids":["https://openalex.org/I169381384","https://openalex.org/I190249584","https://openalex.org/I4210116302"]},{"raw_affiliation_string":"Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands","institution_ids":["https://openalex.org/I169381384"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026248328","display_name":"Sahar El Aidy","orcid":"https://orcid.org/0000-0001-8950-4392","observed_orcids":["https://orcid.org/0000-0001-8950-4392"]},"institutions":[{"id":"https://openalex.org/I169381384","display_name":"University of Groningen","ror":"https://ror.org/012p63287","country_code":"NL","type":"education","lineage":["https://openalex.org/I169381384"]},{"id":"https://openalex.org/I4210142152","display_name":"ORCID","ror":"https://ror.org/04fa4r544","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210142152"]}],"countries":["NL","US"],"is_corresponding":true,"raw_author_name":"Sahar El Aidy","raw_affiliation_strings":["Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands","e-mail: [email\u00a0protected]:orcid.org/0000-0001-8950-4392","to Sahar El Aidy, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborg 7, 9747 AG Groningen, the Netherlands. Tel: +31 0 503632201"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands","institution_ids":["https://openalex.org/I169381384"]},{"raw_affiliation_string":"e-mail: [email\u00a0protected]:orcid.org/0000-0001-8950-4392","institution_ids":["https://openalex.org/I4210142152"]},{"raw_affiliation_string":"to Sahar El Aidy, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborg 7, 9747 AG Groningen, the Netherlands. Tel: +31 0 503632201","institution_ids":["https://openalex.org/I169381384"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5026248328"],"corresponding_institution_ids":["https://openalex.org/I169381384","https://openalex.org/I4210142152"],"apc_list":null,"apc_paid":null,"fwci":0.9666,"has_fulltext":true,"cited_by_count":116,"citation_normalized_percentile":{"value":0.70846075,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"30","issue":"5","first_page":"369","last_page":"377"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9491999745368958,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9491999745368958,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.04580000042915344,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.9980000257492065},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9990000128746033},{"id":"https://openalex.org/keywords/diet","display_name":"diet","score":0.9470000267028809},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7300000190734863},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/early-life-trauma","display_name":"early trauma","score":0.7689999938011169},{"id":"https://openalex.org/keywords/stress-reactivity","display_name":"stress reactivity","score":0.9449999928474426},{"id":"https://openalex.org/keywords/neurotransmitters","display_name":"neurotransmitters","score":0.9049999713897705},{"id":"https://openalex.org/keywords/microbiota-targeted-interventions","display_name":"microbiota-targeted interventions","score":0.6840000152587891},{"id":"https://openalex.org/keywords/psychotherapy","display_name":"psychotherapy","score":0.4880000054836273}],"concepts":[{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.7873799204826355},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.6479305028915405},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.6213347315788269},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5487457513809204},{"id":"https://openalex.org/C177857423","wikidata":"https://www.wikidata.org/wiki/Q17077315","display_name":"Gut\u2013brain axis","level":3,"score":0.5218204855918884},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.479771226644516},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4680086672306061},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3487571179866791},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3105669617652893},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.28633251786231995},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2295532524585724},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.221736878156662},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D003866","descriptor_name":"Depressive Disorder","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D013315","descriptor_name":"Stress, Psychological","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1097/yco.0000000000000350","doi":"https://doi.org/10.1097/yco.0000000000000350","is_oa":false,"landing_page_url":"https://doi.org/10.1097/yco.0000000000000350","pdf_url":null,"source":{"id":"https://openalex.org/S15258550","display_name":"Current Opinion in Psychiatry","issn_l":"0951-7367","issn":["0951-7367","1473-6578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Psychiatry","raw_type":"journal-article"},{"id":"pmid:28654462","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28654462","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in psychiatry","raw_type":"Journal Article"},{"id":"pmh:oai:pure.rug.nl:openaire/dc4649cf-90be-4f43-96b3-f05be9e29d81","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/dc4649cf-90be-4f43-96b3-f05be9e29d81","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Koopman, M, El Aidy, S & MIDtrauma Consortium 2017, 'Depressed gut? The microbiota-diet-inflammation trialogue in depression', Current opinion in psychiatry, vol. 30, no. 5, pp. 369-377. https://doi.org/10.1097/YCO.0000000000000350","raw_type":"info:eu-repo/semantics/review"},{"id":"pmh:rug:oai:pure.rug.nl:publications/9f908333-535b-4d43-9bc6-f2c302be7cc9","doi":null,"is_oa":false,"landing_page_url":"https://www.rug.nl/research/portal/en/publications/depressed-gut-the-microbiotadietinflammation-trialogue-in-depression(9f908333-535b-4d43-9bc6-f2c302be7cc9).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Current opinion in psychiatry, 30(5), 369 - 377","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/dc4649cf-90be-4f43-96b3-f05be9e29d81","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/dc4649cf-90be-4f43-96b3-f05be9e29d81","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Current opinion in psychiatry, 30(5), 369 - 377. LIPPINCOTT WILLIAMS & WILKINS","raw_type":"info:eu-repo/semantics/other"}],"best_oa_location":{"id":"pmh:oai:pure.rug.nl:openaire/dc4649cf-90be-4f43-96b3-f05be9e29d81","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/dc4649cf-90be-4f43-96b3-f05be9e29d81","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Koopman, M, El Aidy, S & MIDtrauma Consortium 2017, 'Depressed gut? The microbiota-diet-inflammation trialogue in depression', Current opinion in psychiatry, vol. 30, no. 5, pp. 369-377. https://doi.org/10.1097/YCO.0000000000000350","raw_type":"info:eu-repo/semantics/review"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320933","display_name":"Rijksuniversiteit Groningen","ror":"https://ror.org/012p63287"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W77332827","https://openalex.org/W112145889","https://openalex.org/W1513447880","https://openalex.org/W1584609572","https://openalex.org/W1605208219","https://openalex.org/W1732771611","https://openalex.org/W1774706107","https://openalex.org/W1986613184","https://openalex.org/W1988309547","https://openalex.org/W1989621427","https://openalex.org/W1995250682","https://openalex.org/W1995819561","https://openalex.org/W1998360317","https://openalex.org/W2000659468","https://openalex.org/W2012953866","https://openalex.org/W2018616965","https://openalex.org/W2026926998","https://openalex.org/W2028221693","https://openalex.org/W2031215299","https://openalex.org/W2031441917","https://openalex.org/W2033386838","https://openalex.org/W2047798386","https://openalex.org/W2052343130","https://openalex.org/W2055122111","https://openalex.org/W2063139961","https://openalex.org/W2064210408","https://openalex.org/W2067275984","https://openalex.org/W2068234766","https://openalex.org/W2072015936","https://openalex.org/W2076423355","https://openalex.org/W2082782542","https://openalex.org/W2091052564","https://openalex.org/W2091259554","https://openalex.org/W2091893560","https://openalex.org/W2095008866","https://openalex.org/W2100275502","https://openalex.org/W2103127225","https://openalex.org/W2109227840","https://openalex.org/W2113822705","https://openalex.org/W2123167284","https://openalex.org/W2127624653","https://openalex.org/W2131398580","https://openalex.org/W2131670325","https://openalex.org/W2131929193","https://openalex.org/W2139694170","https://openalex.org/W2139776015","https://openalex.org/W2146037987","https://openalex.org/W2149515881","https://openalex.org/W2152840561","https://openalex.org/W2152995125","https://openalex.org/W2154679373","https://openalex.org/W2158072789","https://openalex.org/W2164342861","https://openalex.org/W2201607793","https://openalex.org/W2205749696","https://openalex.org/W2238189778","https://openalex.org/W2261084462","https://openalex.org/W2290190425","https://openalex.org/W2292048640","https://openalex.org/W2337492846","https://openalex.org/W2340747659","https://openalex.org/W2396670600","https://openalex.org/W2410619384","https://openalex.org/W2462715376","https://openalex.org/W2469827057","https://openalex.org/W2485902480","https://openalex.org/W2487122696","https://openalex.org/W2525555515","https://openalex.org/W2527444812","https://openalex.org/W2558098334","https://openalex.org/W2560565629","https://openalex.org/W2569180643","https://openalex.org/W2572551054","https://openalex.org/W2574256641","https://openalex.org/W2582048886","https://openalex.org/W4236472310"],"related_works":["https://openalex.org/W2775548228","https://openalex.org/W2890024917","https://openalex.org/W7160209618","https://openalex.org/W3191927178","https://openalex.org/W4392631815","https://openalex.org/W4401852578","https://openalex.org/W7171981372","https://openalex.org/W2608997681","https://openalex.org/W4376506860","https://openalex.org/W2803952832"],"abstract_inverted_index":{"PURPOSE":[0],"OF":[1],"REVIEW:":[2],"According":[3],"to":[4,30,49,61,164,172],"the":[5,20,36,39,50,112,130,144,148,165,174,183],"WHO":[6],"reports,":[7],"around":[8],"350":[9],"million":[10],"people":[11],"worldwide":[12],"suffer":[13],"from":[14],"depression.":[15,55,125,152],"Despite":[16],"its":[17],"high":[18],"prevalence,":[19],"complex":[21],"interaction":[22],"of":[23,38,54,64,96,111,143,177],"multiple":[24],"mechanisms":[25],"underlying":[26],"depression":[27,168],"still":[28],"needs":[29],"be":[31],"elucidated.":[32],"RECENT":[33],"FINDINGS:":[34],"Over":[35],"course":[37],"last":[40],"few":[41],"years,":[42],"several":[43],"neurobiological":[44],"alterations":[45],"have":[46],"been":[47,72],"linked":[48],"development":[51],"and":[52,93,138,151,162],"maintenance":[53],"One":[56],"basic":[57],"process":[58],"that":[59,118],"seems":[60,116],"link":[62],"many":[63],"these":[65],"findings":[66],"is":[67,107],"inflammation.":[68],"Chronic":[69],"inflammation":[70],"has":[71],"associated":[73],"with":[74],"both":[75],"biological":[76],"factors":[77],"such":[78,88],"as":[79,83,85,89],"excessive":[80],"neurotransmitter":[81],"concentrations":[82],"well":[84],"psychological":[86],"processes":[87],"adult":[90],"stress":[91],"reactivity":[92],"a":[94,100,108,122,140],"history":[95],"childhood":[97],"trauma.":[98],"As":[99],"balanced":[101],"microbial":[102],"community,":[103],"modulated":[104],"by":[105,180],"diet,":[106,150],"key":[109],"regulator":[110],"host":[113],"physiology,":[114],"it":[115],"likely":[117],"gut":[119],"microbiota":[120],"plays":[121],"role":[123],"in":[124,167],"SUMMARY:":[126],"The":[127],"review":[128],"summarizes":[129],"existent":[131],"literature":[132],"on":[133],"this":[134],"emerging":[135],"research":[136],"field":[137],"provides":[139],"comprehensive":[141],"overview":[142],"multifaceted":[145],"links":[146],"between":[147],"microbiota,":[149],"Several":[153],"pathways":[154],"linking":[155],"early":[156],"life":[157],"trauma,":[158],"pharmacological":[159],"treatment":[160,176],"effects,":[161],"nutrition":[163],"microbiome":[166],"are":[169],"described":[170],"aiming":[171],"foster":[173],"psychotherapeutic":[175],"depressed":[178],"patients":[179],"interventions":[181],"targeting":[182],"microbiota.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-07-14T00:00:00"}