{"id":"https://openalex.org/W2725645554","doi":"https://doi.org/10.1055/s-2006-957323","title":"Sch\u00e4delbasisimeningeome-eine therapeutische Herausforderung nach Chirurgie: 90Y-DOTATOC Therapie, eine alternative Behandlungsmethode","display_name":"Sch\u00e4delbasisimeningeome-eine therapeutische Herausforderung nach Chirurgie: 90Y-DOTATOC Therapie, eine alternative Behandlungsmethode","publication_year":2007,"publication_date":"2007-03-01","ids":{"openalex":"https://openalex.org/W2725645554","doi":"https://doi.org/10.1055/s-2006-957323","mag":"2725645554"},"language":"de","primary_location":{"id":"doi:10.1055/s-2006-957323","doi":"https://doi.org/10.1055/s-2006-957323","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2006-957323","pdf_url":null,"source":{"id":"https://openalex.org/S162673886","display_name":"Skull base","issn_l":"1052-1453","issn":["1052-1453","1098-9072","1531-5010","1532-0065"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skull Base","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108450712","display_name":"S. Zimmerer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Zimmerer","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014897578","display_name":"Dominik Cordier","orcid":"https://orcid.org/0000-0002-3301-1908","observed_orcids":["https://orcid.org/0000-0002-3301-1908"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. Cordier","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003719756","display_name":"Sigurd Berg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Berg","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005906405","display_name":"B.I. Boerner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B.I. Boerner","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030064957","display_name":"K. Schwenzer-Zimmerer","orcid":"https://orcid.org/0000-0001-5658-3960","observed_orcids":["https://orcid.org/0000-0001-5658-3960"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Schwenzer-Zimmerer","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. M\u00fcller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. M\u00fcller","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084897219","display_name":"A. Merlo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Merlo","raw_affiliation_strings":["Basel, Schweiz"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basel, Schweiz","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.43241208,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"04","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.8598999977111816,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11251","display_name":"Meningioma and schwannoma management","score":0.8598999977111816,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.09440000355243683,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/90y-dotatoc","display_name":"90Y-DOTATOC","score":0.9380000233650208},{"id":"https://openalex.org/keywords/somatostatin-receptor-scintigraphy","display_name":"somatostatin receptor scintigraphy","score":0.7940000295639038},{"id":"https://openalex.org/keywords/radionuclide-therapy","display_name":"radionuclide therapy","score":0.8100000023841858},{"id":"https://openalex.org/keywords/somatostatin-analogs","display_name":"somatostatin analogues","score":0.7009999752044678},{"id":"https://openalex.org/keywords/incomplete-resection","display_name":"incomplete resection","score":0.6539999842643738},{"id":"https://openalex.org/keywords/cavernous-sinus-invasion","display_name":"cavernous sinus invasion","score":0.6520000100135803},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.4410000145435333},{"id":"https://openalex.org/keywords/radiation-dosimetry","display_name":"radiation dosimetry","score":0.3869999945163727}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8637583255767822},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.676522433757782}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-2006-957323","doi":"https://doi.org/10.1055/s-2006-957323","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2006-957323","pdf_url":null,"source":{"id":"https://openalex.org/S162673886","display_name":"Skull base","issn_l":"1052-1453","issn":["1052-1453","1098-9072","1531-5010","1532-0065"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Skull Base","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2725407437","https://openalex.org/W126225429","https://openalex.org/W2199858561","https://openalex.org/W2026942558","https://openalex.org/W2400105969","https://openalex.org/W2279841284","https://openalex.org/W7172508847","https://openalex.org/W2728957318","https://openalex.org/W2725722821","https://openalex.org/W123737891"],"abstract_inverted_index":{"Einleitung:":[0],"Meningeome":[1,105],"der":[2,28,206,231,237,250],"Sch\u00e4delbasis":[3],"bergen":[4],"vielschichtige":[5],"Probleme":[6],"sowohl":[7],"f\u00fcr":[8,13],"den":[9,14,23,34,66,126,151],"Patienten":[10,143,159,176,198,204,216],"als":[11,260],"auch":[12],"Chirurgen":[15],"in":[16,22,30,65,125,245],"sich.":[17],"Die":[18,188,222],"chirurgische":[19],"Behandlung":[20,233],"ist":[21,54,62,71,112],"meisten":[24,67],"F\u00e4llen":[25,68],"unvollst\u00e4ndig,":[26],"da":[27],"Tumor":[29,127,207],"lebenswichtige":[31],"Strukturen":[32,39],"wie":[33,40,59],"Sinus":[35],"cavernosus":[36],"oder":[37,83],"inneliegende":[38],"zum":[41],"Beispiel":[42],"die":[43,79,94,132,168,178,210,218],"Arteria":[44],"carotis":[45],"interna":[46],"infiltrieren":[47],"kann.":[48],"Das":[49],"Ziel":[50],"des":[51,87],"chirurgischen":[52,238],"Eingriffes":[53],"soviel":[55],"Tumormasse":[56,80],"zu":[57,76,81,89,153,240,256],"entfernen":[58],"m\u00f6glich,":[60],"bedauerlicherweise":[61],"kurative":[63],"Chirurgie":[64],"unm\u00f6glich.":[69],"Folglich":[70],"es":[72],"wichtig":[73],"zus\u00e4tzliche":[74],"Behandlungsm\u00f6glichkeiten":[75],"eruieren":[77],"um":[78,150],"verkleinern":[82],"eine":[84,136,169,227,248],"erneute":[85],"Progression":[86],"Tumors":[88],"verhindern.":[90],"Etablierte":[91],"Behandlungsschemata":[92],"schliessen":[93],"Ganz-Hirn-Bestrahlung,":[95],"Gamma":[96],"Knife":[97],"Therapie":[98,182,211,225,239],"und":[99,141,213],"Brachytherapie":[100],"mit":[101,103,144,166],"Seeds":[102],"ein.":[104,173],"weisen":[106],"Somatostainrezeptoren":[107],"auf":[108,209],"\u2013":[109],"90":[110,133,180,223,251],"Y-DOTATOC":[111,134,181,224,252],"ein":[113],"Somatostainanalogon.":[114],"Auf":[115],"diese":[116,175],"Weise":[117],"k\u00f6nnten":[118],"hoch":[119],"energetische":[120],"Strahler":[121],"dem":[122],"Rezeptorstatus":[123],"entsprechend":[124],"appliziert":[128],"werden.":[129],"Demzufolge":[130],"scheint":[131,226],"Radionuklidtherapie":[135],"weitere":[137],"Behandlungsm\u00f6glichkeit":[138],"darzustellen.":[139],"Material":[140],"Methode:":[142],"Meningeomen":[145,235],"erhielten":[146,177],"111":[147],"In-DOTATOC":[148],"Aufnahmen":[149],"Somatostatinrezeptorstatus":[152],"evaluieren.":[154],"Unsere":[155,242],"Serie":[156],"schliesst":[157],"15":[158],"(45\u201384":[160],"Jahre,":[161],"9":[162],"weiblich,":[163],"6":[164],"m\u00e4nnlich)":[165],"Meningeomen,":[167],"hohe":[170],"Rezeptordichte":[171],"aufwiesen,":[172],"Alle":[174],"intraven\u00f6se":[179],"(1\u20136":[183],"Zyklen,":[184],"1700\u201322800":[185],"MBq).":[186],"Ergebnisse:":[187],"klinische":[189],"Durchf\u00fchrung":[190],"erfolgte":[191],"ohne":[192],"Komplikationen.":[193],"Im":[194],"Beobachtungszeitraum":[195],"zeigten":[196],"10":[197],"kein":[199],"weiteres":[200],"Tumorwachstum,":[201],"bei":[202,214,230],"4":[203],"schien":[205],"nicht":[208],"anzusprechen":[212],"einem":[215],"waren":[217],"Ergebnisse":[219,243],"fraglich.":[220],"Schlussfolgerung:":[221],"vielversprechende":[228],"Therapieoption":[229],"zus\u00e4tzlichen":[232],"von":[234,258],"nach":[236],"sein.":[241],"zeigten,":[244],"dieser":[246],"Gruppe":[247],"Wirksamkeit":[249],"Therapie,":[253],"das":[254],"Tumorwachstum":[255],"stoppen":[257],"mehr":[259],"50%.":[261]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2017-07-14T00:00:00"}