{"id":"https://openalex.org/W2715330949","doi":null,"title":"Replicability of Classification Procedures for Gene Expression Data","display_name":"Replicability of Classification Procedures for Gene Expression Data","publication_year":2017,"publication_date":"2017-05-01","ids":{"openalex":"https://openalex.org/W2715330949","mag":"2715330949"},"language":"en","primary_location":{"id":"pmh:oai:kb.osu.edu:1811/80509","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1811/80509","pdf_url":null,"source":{"id":"https://openalex.org/S4306402304","display_name":"The Knowledge Bank (The Ohio State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52357470","host_organization_name":"The Ohio State University","host_organization_lineage":["https://openalex.org/I52357470"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058596583","display_name":"Dinank Gupta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Dinank Gupta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5058596583"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12535","display_name":"Machine Learning and Data Classification","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/replicability","display_name":"replicability","score":0.6830000281333923},{"id":"https://openalex.org/keywords/classification-error-estimation","display_name":"classification error estimation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/gene-expression-data","display_name":"gene expression data","score":0.746999979019165},{"id":"https://openalex.org/keywords/cancer-subtyping","display_name":"cancer subtyping","score":0.5540000200271606},{"id":"https://openalex.org/keywords/small-sample-size","display_name":"small sample size","score":0.800000011920929},{"id":"https://openalex.org/keywords/rna-seq","display_name":"RNA-seq","score":0.9190000295639038},{"id":"https://openalex.org/keywords/microarray","display_name":"microarray","score":0.9449999928474426},{"id":"https://openalex.org/keywords/sample-size-calculation","display_name":"sample size determination","score":0.7639999985694885},{"id":"https://openalex.org/keywords/cross-validation","display_name":"cross-validation","score":0.4729999899864197},{"id":"https://openalex.org/keywords/generalizability","display_name":"generalizability","score":0.41499999165534973}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.51612389087677},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.45777982473373413},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.45669206976890564},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4057428240776062},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3928910493850708},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.38250380754470825},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3604618012905121},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3531704545021057},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.32632970809936523},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3134205937385559},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.059179335832595825}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:kb.osu.edu:1811/80509","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1811/80509","pdf_url":null,"source":{"id":"https://openalex.org/S4306402304","display_name":"The Knowledge Bank (The Ohio State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52357470","host_organization_name":"The Ohio State University","host_organization_lineage":["https://openalex.org/I52357470"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2715330949","doi":null,"is_oa":false,"landing_page_url":"http://kb.osu.edu/dspace/handle/1811/80509","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1915008591","https://openalex.org/W2021084622","https://openalex.org/W2030764127","https://openalex.org/W2035038062","https://openalex.org/W2094815068","https://openalex.org/W2114482012","https://openalex.org/W2121211805","https://openalex.org/W2136487516","https://openalex.org/W2142165994","https://openalex.org/W2152239989","https://openalex.org/W2154431984","https://openalex.org/W2156631105","https://openalex.org/W2331384579"],"related_works":["https://openalex.org/W2034500646","https://openalex.org/W2169638850","https://openalex.org/W7100657023","https://openalex.org/W7100660726","https://openalex.org/W2085538190","https://openalex.org/W2115041568","https://openalex.org/W2125056473","https://openalex.org/W2106452518","https://openalex.org/W2134258050","https://openalex.org/W7097647718"],"abstract_inverted_index":{"Pattern":[0],"classification":[1,81,112,147],"is":[2,28,51,93,108],"a":[3,90,141,180,184,191],"branch":[4],"of":[5,23,39,48,79,105,118,131,199],"statistics":[6],"and":[7,89,148,160,165,170],"machine":[8],"learning":[9],"that":[10,152,179],"uses":[11],"labeled":[12],"samples":[13],"to":[14,29,67,95,144,177,183],"predict":[15],"information":[16],"about":[17],"unlabeled":[18],"ones.":[19],"A":[20],"common":[21],"application":[22],"this":[24,75,136],"theory":[25],"in":[26,59,156,161,190],"medicine":[27],"classify":[30],"cancer":[31],"patients":[32],"into":[33],"subtypes":[34],"based":[35],"on":[36,128,163,173],"the":[37,46,49,71,77,80,84,103,111,119,129,157,174],"patterns":[38,58,65],"their":[40],"gene":[41,167],"expression":[42,168],"profiles.":[43],"What":[44],"determines":[45,86],"validity":[47,88],"procedure":[50,181],"not":[52],"whether":[53,63],"one":[54],"can":[55],"find":[56],"these":[57,64],"observed":[60,106],"data,":[61,169],"but":[62],"generalize":[66,189],"unobserved":[68],"data":[69,107],"from":[70],"same":[72],"population.":[73],"In":[74,135],"regard,":[76],"error":[78,113,120,149],"rule":[82],"over":[83],"population":[85],"its":[87],"key":[91],"issue":[92],"how":[94],"estimate":[96],"it.":[97],"\\nIn":[98],"small":[99,132,185],"sample":[100,133,175],"situations,":[101],"where":[102],"number":[104],"small,":[109],"estimating":[110],"becomes":[114],"problematic":[115],"as":[116],"most":[117],"estimators":[121],"have":[122],"high":[123],"variance.":[124],"This":[125],"raises":[126],"doubts":[127],"replicability":[130,142],"studies.":[134],"thesis,":[137],"I":[138],"will":[139,188],"use":[140],"index":[143],"asses":[145],"multiple":[146],"estimation":[150],"procedures":[151],"are":[153],"commonly":[154],"used":[155],"medical":[158],"community,":[159],"particular,":[162],"RNA-seq":[164],"microarray":[166],"provide":[171],"suggestions":[172],"size":[176],"ensure":[178],"applied":[182],"preliminary":[186],"study":[187,194],"large":[192],"follow-on":[193],"with":[195],"an":[196],"acceptable":[197],"margin":[198],"error.":[200]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2017-06-30T00:00:00"}