{"id":"https://openalex.org/W2695049005","doi":null,"title":"Cooperative Bacterial Interactions Mediate Resistance To Colonization By Intestinal Pathogens","display_name":"Cooperative Bacterial Interactions Mediate Resistance To Colonization By Intestinal Pathogens","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2695049005","mag":"2695049005"},"language":"en","primary_location":{"id":"pmh:oai:ecommons.cornell.edu:1813/64721","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1813/64721","pdf_url":null,"source":{"id":"https://openalex.org/S4306400757","display_name":"eCommons (Cornell University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dissertation or thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/1813/64721","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024424583","display_name":"Silvia Caballero","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Caballero, Silvia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5024424583"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colonization-resistance","display_name":"colonization resistance","score":0.925000011920929},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9129999876022339},{"id":"https://openalex.org/keywords/vancomycin-resistant-enterococci","display_name":"vancomycin-resistant enterococci","score":0.9190000295639038},{"id":"https://openalex.org/keywords/carbapenem-resistant-klebsiella-pneumoniae","display_name":"carbapenem-resistant Klebsiella pneumoniae","score":0.9890000224113464},{"id":"https://openalex.org/keywords/bacterial-coexistence","display_name":"bacterial coexistence","score":0.5879999995231628},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.6430000066757202},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.8420000076293945},{"id":"https://openalex.org/keywords/opportunistic-pathogens","display_name":"opportunistic pathogens","score":0.7649999856948853},{"id":"https://openalex.org/keywords/commensal-bacteria","display_name":"commensal bacteria","score":0.781000018119812},{"id":"https://openalex.org/keywords/antibiotic-perturbation","display_name":"antibiotic perturbation","score":0.6039999723434448}],"concepts":[{"id":"https://openalex.org/C2776927270","wikidata":"https://www.wikidata.org/wiki/Q815962","display_name":"Colonization","level":2,"score":0.7516618371009827},{"id":"https://openalex.org/C189506811","wikidata":"https://www.wikidata.org/wiki/Q5148442","display_name":"Colonisation resistance","level":3,"score":0.7188054919242859},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5208771228790283},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.4623391032218933},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.45074090361595154},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.19227513670921326}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:ecommons.cornell.edu:1813/64721","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1813/64721","pdf_url":null,"source":{"id":"https://openalex.org/S4306400757","display_name":"eCommons (Cornell University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dissertation or thesis"}],"best_oa_location":{"id":"pmh:oai:ecommons.cornell.edu:1813/64721","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/1813/64721","pdf_url":null,"source":{"id":"https://openalex.org/S4306400757","display_name":"eCommons (Cornell University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"dissertation or thesis"},"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3005019778","https://openalex.org/W1863177951","https://openalex.org/W2613064135","https://openalex.org/W6958630511","https://openalex.org/W7095741141","https://openalex.org/W4406946489","https://openalex.org/W2084057318","https://openalex.org/W7223419351","https://openalex.org/W7166121322","https://openalex.org/W2145783127"],"abstract_inverted_index":{"The":[0,157],"diverse":[1],"microbial":[2,143],"populations":[3],"constituting":[4],"the":[5,26,38,65,84,100,105,110,123,127,130,135,148,166,186,208,238,249],"intestinal":[6,191,256],"microbiota":[7,66,72,85,106,131],"promote":[8],"immune":[9],"development,":[10],"nutrient":[11],"digestion":[12],"and":[13,25,48,51,67,82,92,125,172,184,188,203,219,244],"colonization":[14,152,195,221],"resistance":[15,138,196,222],"against":[16,197,223],"invading":[17],"pathogens.":[18],"Due":[19],"to":[20,89,108,139,151,164,189,216,254],"their":[21],"complex":[22,239],"metabolic":[23],"requirements":[24],"consequent":[27],"difficulty":[28],"culturing":[29],"them,":[30],"they":[31],"remained,":[32],"until":[33],"recently,":[34],"largely":[35],"uncharacterized.":[36],"In":[37],"past":[39],"decade,":[40],"deep":[41],"nucleic":[42],"acid":[43],"sequencing":[44],"platforms,":[45],"new":[46,252],"computational":[47],"bioinformatics":[49],"tools":[50],"full":[52],"genome":[53],"characterization":[54],"of":[55,64,80,96,99,104,112,129,137,142,251],"several":[56],"hundred":[57],"commensal":[58],"bacterial":[59,117,230],"species":[60,118,231],"have":[61,180],"facilitated":[62],"studies":[63,158],"revealed":[68],"that":[69,83,168,201,220],"differences":[70],"in":[71,133,160,212],"composition":[73,128],"can":[74,86,225],"be":[75,87,226],"associated":[76],"with":[77,145],"a":[78],"myriad":[79],"conditions":[81],"manipulated":[88],"prevent,":[90],"reduce":[91],"even":[93],"cure":[94],"some":[95],"them.":[97],"One":[98],"most":[101],"critical":[102],"functions":[103],"is":[107],"prevent":[109],"expansion":[111],"disease-":[113],"causing":[114],"organisms.":[115],"Different":[116],"exert":[119],"different":[120],"roles":[121],"within":[122,207],"intestine":[124,209],"therefore,":[126],"determines,":[132],"part,":[134],"level":[136],"infection.":[140],"Perturbation":[141],"communities":[144],"antibiotics":[146],"renders":[147],"host":[149,187],"susceptible":[150],"by":[153,228],"opportunistic":[154],"antibiotic-resistant":[155],"bacteria.":[156],"discussed":[159],"this":[161],"dissertation":[162],"aim":[163],"determine":[165],"impact":[167],"vancomycin-resistant":[169],"Enterococcus":[170],"(VRE)":[171],"carbapenem-resistant":[173],"Klebsiella":[174],"pneumoniae,":[175],"two":[176,229],"common":[177],"hospital-acquired":[178],"infections,":[179],"on":[181,185],"each":[182,217],"other":[183,218],"identify":[190],"bacteria":[192,243],"responsible":[193],"for":[194,248],"VRE.":[198],"We":[199],"demonstrate":[200],"VRE":[202,224],"K.":[204],"pneumoniae":[205],"coexist":[206],"despite":[210,232],"residing":[211],"very":[213],"close":[214],"proximity":[215],"mediated":[227],"antibiotic":[233],"treatment.":[234],"This":[235],"work":[236],"highlights":[237],"interplay":[240],"between":[241],"gut":[242],"has":[245],"important":[246],"implications":[247],"development":[250],"therapeutics":[253],"treat":[255],"infections.":[257]},"counts_by_year":[],"updated_date":"2026-09-11T09:22:31.653822","created_date":"2025-10-10T00:00:00"}