{"id":"https://openalex.org/W265352907","doi":null,"title":"[Effect of low-dose polyethylene glycol 4000 on fecal consistency and dilution water in healthy subjects].","display_name":"[Effect of low-dose polyethylene glycol 4000 on fecal consistency and dilution water in healthy subjects].","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W265352907","mag":"265352907","pmid":"https://pubmed.ncbi.nlm.nih.gov/9091392"},"language":"fr","primary_location":{"id":"pmid:9091392","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9091392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterologie clinique et biologique","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109890761","display_name":"J J Bernier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087990","display_name":"H\u00f4pital Saint Lazare","ror":"https://ror.org/007hzv648","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210087990"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J J Bernier","raw_affiliation_strings":["H\u00f4pital Saint-Lazare, Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00f4pital Saint-Lazare, Paris","institution_ids":["https://openalex.org/I4210087990"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072900620","display_name":"Yves Donazzolo","orcid":"https://orcid.org/0009-0002-4314-607X","observed_orcids":["https://orcid.org/0009-0002-4314-607X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Donazzolo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5476,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.66227975,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"21","issue":"1","first_page":"7","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10418","display_name":"Pelvic floor disorders treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyethylene-glycol","display_name":"polyethylene glycol","score":0.9089999794960022},{"id":"https://openalex.org/keywords/fecal-consistency","display_name":"stool consistency","score":0.7210000157356262},{"id":"https://openalex.org/keywords/laxative-effect","display_name":"laxative effect","score":0.5849999785423279},{"id":"https://openalex.org/keywords/fecal-water-content","display_name":"fecal water content","score":0.5559999942779541},{"id":"https://openalex.org/keywords/healthy-volunteers","display_name":"healthy volunteers","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.8151473999023438},{"id":"https://openalex.org/C96618451","wikidata":"https://www.wikidata.org/wiki/Q3028008","display_name":"Dilution","level":2,"score":0.7524539232254028},{"id":"https://openalex.org/C193230392","wikidata":"https://www.wikidata.org/wiki/Q1663054","display_name":"Ingestion","level":2,"score":0.7466697096824646},{"id":"https://openalex.org/C54400483","wikidata":"https://www.wikidata.org/wiki/Q1793202","display_name":"PEG ratio","level":2,"score":0.7185640931129456},{"id":"https://openalex.org/C2776964284","wikidata":"https://www.wikidata.org/wiki/Q410083","display_name":"Polyethylene glycol","level":2,"score":0.669082760810852},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5497971177101135},{"id":"https://openalex.org/C171679685","wikidata":"https://www.wikidata.org/wiki/Q3707695","display_name":"Isotope dilution","level":3,"score":0.5081040859222412},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.49981093406677246},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.43848228454589844},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3000759482383728},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26127660274505615},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.25047963857650757},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.2164875566959381},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16634449362754822},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13427019119262695},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001834","descriptor_name":"Body Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004573","descriptor_name":"Electrolytes","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005772","descriptor_name":"Gastrointestinal Transit","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D011092","descriptor_name":"Polyethylene Glycols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:9091392","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9091392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterologie clinique et biologique","raw_type":"Clinical Trial"},{"id":"mag:265352907","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9091392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W76608741","https://openalex.org/W2426196609","https://openalex.org/W2416065502","https://openalex.org/W2024011862","https://openalex.org/W2472556146","https://openalex.org/W2165844124","https://openalex.org/W2407559332","https://openalex.org/W2411863136","https://openalex.org/W7098615935","https://openalex.org/W2004499185"],"abstract_inverted_index":{"OBJECTIVES:":[0],"The":[1],"aim":[2],"of":[3,23,26,73,89,117,164],"the":[4,12,21,35,71,85,115,151,158],"study":[5],"was":[6,54,60],"to":[7,65,150,179],"assess":[8],"in":[9,14,107,181],"normal":[10],"subjects":[11],"changes":[13,180],"stool":[15,47],"consistency":[16,152],"and":[17,42,67,96,103,122,153],"dilution":[18,99,123,154,182],"water":[19,33,36,124,155,183],"during":[20,56,70,114,157],"ingestion":[22,72,116],"small":[24],"doses":[25,163],"polyethylene":[27],"glycol":[28],"(PEG)":[29],"5.9":[30],"g/d.":[31],"Dilution":[32],"is":[34,177],"located":[37],"outside":[38,185],"solid":[39,187],"structures":[40],"(bacteria":[41],"food":[43],"residue).":[44],"METHODS:":[45],"Each":[46],"passed":[48],"by":[49],"16":[50],"non-constipated":[51],"male":[52],"volunteers":[53],"collected":[55,69,79],"3":[57],"weeks.":[58],"PEG":[59,74,90,104,118,143,165],"ingested":[61],"from":[62],"days":[63],"1":[64],"7,":[66],"stools":[68,169],"were":[75,105,112],"compared":[76],"with":[77],"those":[78],"at":[80],"least":[81],"24":[82],"h":[83],"after":[84],"last":[86],"fecal":[87,92,186],"excretion":[88],"(control":[91],"data).":[93],"Consistency,":[94],"fresh":[95],"dry":[97],"weight,":[98],"water,":[100],"nitrogen,":[101],"electrolytes":[102],"quantified":[106],"each":[108],"stool.":[109],"RESULTS:":[110],"Stools":[111],"softer":[113],"(P":[119],"<":[120,141],"0.01)":[121],"increased":[125],"significantly":[126],"(49.4":[127],"+/-":[128,132,138],"1.7":[129],"vs":[130],"37.6":[131],"2.6":[133],"mL/100":[134],"g":[135],"feces,":[136],"mean":[137],"SD,":[139],"P":[140],"0.02).":[142],"induced":[144],"variable":[145],"effects":[146],"among":[147],"individuals":[148],"according":[149],"measured":[156],"control":[159],"period.":[160],"CONCLUSION:":[161],"Low":[162],"(5.9":[166],"g/d)":[167],"soften":[168],"particularly":[170],"when":[171],"feces":[172],"are":[173],"harder.":[174],"This":[175],"effect":[176],"due":[178],"(water":[184],"structures).":[188]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}