{"id":"https://openalex.org/W263899431","doi":"https://doi.org/10.1007/978-1-84882-019-7_6","title":"Role of Bone Microenvironment/Metastatic Niche in Cancer Progression","display_name":"Role of Bone Microenvironment/Metastatic Niche in Cancer Progression","publication_year":2009,"publication_date":"2009-04-30","ids":{"openalex":"https://openalex.org/W263899431","doi":"https://doi.org/10.1007/978-1-84882-019-7_6","mag":"263899431"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-84882-019-7_6","doi":"https://doi.org/10.1007/978-1-84882-019-7_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-84882-019-7_6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone and Cancer","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2753430594","display_name":"Bone and Cancer"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034235247","display_name":"Anna J. Podolanczuk","orcid":"https://orcid.org/0000-0002-9559-1485","observed_orcids":["https://orcid.org/0000-0002-9559-1485"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Podolanczuk","raw_affiliation_strings":["Departments of Pediatrics and Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA","Weill-Cornell Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Cell and Developmental Biology, Weill Cornell Medical College, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Weill-Cornell Medical College","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053302921","display_name":"Bethan Psaila","orcid":"https://orcid.org/0000-0001-8198-9663","observed_orcids":["https://orcid.org/0000-0001-8198-9663"]},"institutions":[{"id":"https://openalex.org/I2801748203","display_name":"Hammersmith Hospital","ror":"https://ror.org/05jg8yp15","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300","https://openalex.org/I2801748203"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bethan Psaila","raw_affiliation_strings":["Department of Haematology, Hammersmith Hospital, Imperial College School of Medicine, London, UK","Hammersmith Hospital, Imperial College School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Haematology, Hammersmith Hospital, Imperial College School of Medicine, London, UK","institution_ids":["https://openalex.org/I2801748203","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Hammersmith Hospital, Imperial College School of Medicine","institution_ids":["https://openalex.org/I2801748203","https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044701800","display_name":"David C. Lyden","orcid":"https://orcid.org/0000-0003-0193-4131","observed_orcids":["https://orcid.org/0000-0003-0193-4131"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Lyden","raw_affiliation_strings":["Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA","Weill-Cornell Medical College"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Weill Cornell Medical College, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Weill-Cornell Medical College","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.16722973,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"89","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.7548999786376953,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.7548999786376953,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.043699998408555984,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments","score":0.032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-marrow-microenvironment","display_name":"bone marrow microenvironment","score":0.7289999723434448},{"id":"https://openalex.org/keywords/metastatic-niche","display_name":"metastatic niche","score":0.9520000219345093},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.871999979019165},{"id":"https://openalex.org/keywords/bone-marrow-stroma","display_name":"bone marrow stroma","score":0.7879999876022339},{"id":"https://openalex.org/keywords/bone-marrow-derived-cells","display_name":"bone marrow-derived cells","score":0.9459999799728394},{"id":"https://openalex.org/keywords/hematopoietic-system","display_name":"hematopoietic system","score":0.753000020980835},{"id":"https://openalex.org/keywords/stem-cell-niche","display_name":"stem cell niche","score":0.6949999928474426},{"id":"https://openalex.org/keywords/disseminated-tumor-cells","display_name":"disseminated tumor cells","score":0.8309999704360962},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6909999847412109},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.8859999775886536}],"concepts":[{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.6889147758483887},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.6352304220199585},{"id":"https://openalex.org/C2780283643","wikidata":"https://www.wikidata.org/wiki/Q2110267","display_name":"Primary tumor","level":4,"score":0.5465197563171387},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5263285040855408},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.47579821944236755},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.4723930060863495},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45981132984161377},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4441917836666107},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.43828505277633667},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.4290342926979065},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3865610361099243},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37412387132644653},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.34787800908088684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1500140130519867},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.118557870388031},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.07896575331687927}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-84882-019-7_6","doi":"https://doi.org/10.1007/978-1-84882-019-7_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-84882-019-7_6","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone and Cancer","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W1266604479","https://openalex.org/W1485875137","https://openalex.org/W1506680628","https://openalex.org/W1570971207","https://openalex.org/W1815183856","https://openalex.org/W1815266527","https://openalex.org/W1875554126","https://openalex.org/W1892965830","https://openalex.org/W1916210108","https://openalex.org/W1925042033","https://openalex.org/W1964052195","https://openalex.org/W1967532587","https://openalex.org/W1974643611","https://openalex.org/W1975198479","https://openalex.org/W1978577068","https://openalex.org/W1978591675","https://openalex.org/W1979472633","https://openalex.org/W1981175925","https://openalex.org/W1983798380","https://openalex.org/W1985136204","https://openalex.org/W1985727076","https://openalex.org/W1986471913","https://openalex.org/W1987662957","https://openalex.org/W1988698591","https://openalex.org/W1992837561","https://openalex.org/W1997374162","https://openalex.org/W1997576503","https://openalex.org/W2000292756","https://openalex.org/W2004280628","https://openalex.org/W2004870721","https://openalex.org/W2007599495","https://openalex.org/W2008681940","https://openalex.org/W2017176305","https://openalex.org/W2017767253","https://openalex.org/W2017802236","https://openalex.org/W2018867485","https://openalex.org/W2023187622","https://openalex.org/W2023624246","https://openalex.org/W2025476423","https://openalex.org/W2033363278","https://openalex.org/W2033601733","https://openalex.org/W2042773343","https://openalex.org/W2044302244","https://openalex.org/W2046833383","https://openalex.org/W2047870699","https://openalex.org/W2054627635","https://openalex.org/W2059425291","https://openalex.org/W2060551076","https://openalex.org/W2061257207","https://openalex.org/W2062809449","https://openalex.org/W2062945727","https://openalex.org/W2067020307","https://openalex.org/W2073079990","https://openalex.org/W2076165474","https://openalex.org/W2082833890","https://openalex.org/W2084740377","https://openalex.org/W2086641174","https://openalex.org/W2087963453","https://openalex.org/W2092074451","https://openalex.org/W2094912585","https://openalex.org/W2094964650","https://openalex.org/W2095554214","https://openalex.org/W2099533955","https://openalex.org/W2103004412","https://openalex.org/W2105374622","https://openalex.org/W2106278719","https://openalex.org/W2108151385","https://openalex.org/W2108296770","https://openalex.org/W2111042503","https://openalex.org/W2113500634","https://openalex.org/W2113784075","https://openalex.org/W2114653516","https://openalex.org/W2121861557","https://openalex.org/W2126712079","https://openalex.org/W2128985829","https://openalex.org/W2131130317","https://openalex.org/W2139178975","https://openalex.org/W2146530991","https://openalex.org/W2148693026","https://openalex.org/W2153503145","https://openalex.org/W2154353368","https://openalex.org/W2156323704","https://openalex.org/W2157215186","https://openalex.org/W2158048826","https://openalex.org/W2159241628","https://openalex.org/W2160450758","https://openalex.org/W2163924896"],"related_works":["https://openalex.org/W2013107571","https://openalex.org/W2049528074","https://openalex.org/W1983542490","https://openalex.org/W4405374772","https://openalex.org/W1500493219","https://openalex.org/W3177628791","https://openalex.org/W2157792277","https://openalex.org/W2108424765","https://openalex.org/W4285107197","https://openalex.org/W1987660792"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}