{"id":"https://openalex.org/W26322649","doi":"https://doi.org/10.1007/978-1-4613-1237-6_19","title":"Molecular Basis for Depressed Contractile Performance in Human Heart Failure","display_name":"Molecular Basis for Depressed Contractile Performance in Human Heart Failure","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W26322649","doi":"https://doi.org/10.1007/978-1-4613-1237-6_19","mag":"26322649"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4613-1237-6_19","doi":"https://doi.org/10.1007/978-1-4613-1237-6_19","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4613-1237-6_19","pdf_url":null,"source":{"id":"https://openalex.org/S2764412464","display_name":"Developments in cardiovascular medicine","issn_l":"0166-9842","issn":["0166-9842","2542-8373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in Cardiovascular Medicine","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W583022067","display_name":"Heart Hypertrophy and Failure"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061749504","display_name":"Norman R. Alpert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Norman R. Alpert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013428416","display_name":"L. A. Mulieri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Louis A. Mulieri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5004362368","display_name":"Gerd P Hasenfuss","orcid":"https://orcid.org/0000-0002-5942-361X","observed_orcids":["https://orcid.org/0000-0002-5942-361X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerd Hasenfuss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.02272727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"241","last_page":"255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.9315999746322632,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.043299999088048935,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9869999885559082},{"id":"https://openalex.org/keywords/excitation-contraction-coupling","display_name":"excitation-contraction coupling","score":0.9539999961853027},{"id":"https://openalex.org/keywords/calcium-handling","display_name":"calcium handling","score":0.9459999799728394},{"id":"https://openalex.org/keywords/mitral-regurgitation","display_name":"mitral regurgitation","score":0.7919999957084656},{"id":"https://openalex.org/keywords/fluid-overload","display_name":"fluid overload","score":0.9290000200271606},{"id":"https://openalex.org/keywords/idiopathic-dilated-cardiomyopathy","display_name":"idiopathic dilated cardiomyopathy","score":0.9610000252723694},{"id":"https://openalex.org/keywords/myocardial-mechanical-properties","display_name":"myocardial mechanical properties","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7442635297775269},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6883909106254578},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.67192542552948},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6677602529525757},{"id":"https://openalex.org/C2776383484","wikidata":"https://www.wikidata.org/wiki/Q283656","display_name":"Dilated cardiomyopathy","level":3,"score":0.6175578832626343},{"id":"https://openalex.org/C24595384","wikidata":"https://www.wikidata.org/wiki/Q17143767","display_name":"Volume overload","level":3,"score":0.5706035494804382},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.4891267418861389},{"id":"https://openalex.org/C103486182","wikidata":"https://www.wikidata.org/wiki/Q1216236","display_name":"Isometric exercise","level":2,"score":0.4741969704627991},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.437685489654541},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.43533599376678467},{"id":"https://openalex.org/C2778271984","wikidata":"https://www.wikidata.org/wiki/Q17126794","display_name":"Pressure overload","level":4,"score":0.43242475390434265},{"id":"https://openalex.org/C2993373945","wikidata":"https://www.wikidata.org/wiki/Q268292","display_name":"Mitral regurgitation","level":2,"score":0.42587149143218994},{"id":"https://openalex.org/C99398487","wikidata":"https://www.wikidata.org/wiki/Q257319","display_name":"Cardiac cycle","level":2,"score":0.4112558662891388},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.25387871265411377},{"id":"https://openalex.org/C3018791406","wikidata":"https://www.wikidata.org/wiki/Q945225","display_name":"Cardiac hypertrophy","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4613-1237-6_19","doi":"https://doi.org/10.1007/978-1-4613-1237-6_19","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4613-1237-6_19","pdf_url":null,"source":{"id":"https://openalex.org/S2764412464","display_name":"Developments in cardiovascular medicine","issn_l":"0166-9842","issn":["0166-9842","2542-8373"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in Cardiovascular Medicine","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7699999809265137}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W6528789","https://openalex.org/W8120957","https://openalex.org/W145482395","https://openalex.org/W789458867","https://openalex.org/W1469756213","https://openalex.org/W1532810116","https://openalex.org/W1534368977","https://openalex.org/W1561982601","https://openalex.org/W1581028088","https://openalex.org/W1977051351","https://openalex.org/W1979801633","https://openalex.org/W1980685237","https://openalex.org/W1989703871","https://openalex.org/W1992939744","https://openalex.org/W2000740519","https://openalex.org/W2002931457","https://openalex.org/W2006229710","https://openalex.org/W2007098899","https://openalex.org/W2007533297","https://openalex.org/W2008565916","https://openalex.org/W2012592862","https://openalex.org/W2026145805","https://openalex.org/W2029309638","https://openalex.org/W2035801904","https://openalex.org/W2036421415","https://openalex.org/W2036717675","https://openalex.org/W2038494318","https://openalex.org/W2044110796","https://openalex.org/W2052905909","https://openalex.org/W2057842141","https://openalex.org/W2110787501","https://openalex.org/W2122991452","https://openalex.org/W2127892601","https://openalex.org/W2127917887","https://openalex.org/W2133397439","https://openalex.org/W2144796862","https://openalex.org/W2163374398","https://openalex.org/W2197191919","https://openalex.org/W2208075919","https://openalex.org/W2418267971","https://openalex.org/W2464778036","https://openalex.org/W4299731235"],"related_works":["https://openalex.org/W134700293","https://openalex.org/W2223087271","https://openalex.org/W65194918","https://openalex.org/W194993830","https://openalex.org/W33279527","https://openalex.org/W1965506481","https://openalex.org/W2914932442","https://openalex.org/W1608092539","https://openalex.org/W2341160847","https://openalex.org/W208013850"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}