{"id":"https://openalex.org/W2626515639","doi":"https://doi.org/10.5152/eurjrheum.2017.17066","title":"Aneurysm of the ascending aorta in systemic lupus erythematosus: Case report and review of the literature","display_name":"Aneurysm of the ascending aorta in systemic lupus erythematosus: Case report and review of the literature","publication_year":2017,"publication_date":"2017-06-12","ids":{"openalex":"https://openalex.org/W2626515639","doi":"https://doi.org/10.5152/eurjrheum.2017.17066","mag":"2626515639","pmid":"https://pubmed.ncbi.nlm.nih.gov/28638687","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5473449"},"language":"en","primary_location":{"id":"doi:10.5152/eurjrheum.2017.17066","doi":"https://doi.org/10.5152/eurjrheum.2017.17066","is_oa":true,"landing_page_url":"https://doi.org/10.5152/eurjrheum.2017.17066","pdf_url":"http://eurjrheumatol.org/en/aneurysm-of-the-ascending-aorta-in-systemic-lupus-erythematosus-case-report-and-review-of-the-literature-1617893","source":{"id":"https://openalex.org/S2764417355","display_name":"European Journal of Rheumatology","issn_l":"2147-9720","issn":["2147-9720","2148-4279"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-20","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4310318309","host_organization_name":"AVES Yayincilik","host_organization_lineage":["https://openalex.org/P4310318309"],"host_organization_lineage_names":["AVES Yayincilik"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Rheumatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://eurjrheumatol.org/en/aneurysm-of-the-ascending-aorta-in-systemic-lupus-erythematosus-case-report-and-review-of-the-literature-1617893","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025471051","display_name":"H\u00e8ctor Corominas","orcid":"https://orcid.org/0000-0002-7738-6787","observed_orcids":["https://orcid.org/0000-0002-7738-6787","https://orcid.org/0000-0001-7956-3866"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hector Corominas","raw_affiliation_strings":["Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059497696","display_name":"Maria Tsokos","orcid":"https://orcid.org/0000-0001-8072-1358","observed_orcids":["https://orcid.org/0000-0001-8072-1358"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Tsokos","raw_affiliation_strings":["Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110010341","display_name":"Martha Quezado","orcid":"https://orcid.org/0009-0004-0941-8662","observed_orcids":["https://orcid.org/0009-0004-0941-8662"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martha Quezado","raw_affiliation_strings":["Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027542245","display_name":"George C. Tsokos","orcid":"https://orcid.org/0000-0001-9589-2360","observed_orcids":["https://orcid.org/0000-0001-9589-2360"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George C. Tsokos","raw_affiliation_strings":["Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5025471051"],"corresponding_institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":0.9049,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.76127611,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"4","issue":"2","first_page":"133","last_page":"135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.46560001373291016,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.46560001373291016,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.21199999749660492,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.14489999413490295,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ascending-aortic-aneurysm","display_name":"ascending aortic aneurysm","score":0.8790000081062317},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/aortic-dissection","display_name":"aortic dissection","score":0.5979999899864197},{"id":"https://openalex.org/keywords/pericarditis","display_name":"pericarditis","score":0.7129999995231628},{"id":"https://openalex.org/keywords/mitral-valve-vegetation","display_name":"mitral valve vegetation","score":0.8420000076293945},{"id":"https://openalex.org/keywords/aortic-aneurysm-repair","display_name":"aortic aneurysm repair","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9581310153007507},{"id":"https://openalex.org/C2775872228","wikidata":"https://www.wikidata.org/wiki/Q82504","display_name":"Endocarditis","level":2,"score":0.7307036519050598},{"id":"https://openalex.org/C2778249958","wikidata":"https://www.wikidata.org/wiki/Q2349469","display_name":"Ascending aorta","level":3,"score":0.7176863551139832},{"id":"https://openalex.org/C2776098176","wikidata":"https://www.wikidata.org/wiki/Q189389","display_name":"Aneurysm","level":2,"score":0.6919760704040527},{"id":"https://openalex.org/C2781001862","wikidata":"https://www.wikidata.org/wiki/Q501561","display_name":"Pericarditis","level":2,"score":0.6354904174804688},{"id":"https://openalex.org/C2777323849","wikidata":"https://www.wikidata.org/wiki/Q616003","display_name":"Aortic aneurysm","level":3,"score":0.5532627701759338},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.5224229693412781},{"id":"https://openalex.org/C2776864027","wikidata":"https://www.wikidata.org/wiki/Q615993","display_name":"Thoracic aorta","level":3,"score":0.49306079745292664},{"id":"https://openalex.org/C2775862295","wikidata":"https://www.wikidata.org/wiki/Q2660911","display_name":"Dissection (medical)","level":2,"score":0.45276111364364624},{"id":"https://openalex.org/C2775915377","wikidata":"https://www.wikidata.org/wiki/Q188297","display_name":"Lupus erythematosus","level":3,"score":0.44540631771087646},{"id":"https://openalex.org/C2780847584","wikidata":"https://www.wikidata.org/wiki/Q3616648","display_name":"Thoracic aortic aneurysm","level":4,"score":0.41137710213661194},{"id":"https://openalex.org/C2910348082","wikidata":"https://www.wikidata.org/wiki/Q19919956","display_name":"Cervical Artery","level":3,"score":0.41017383337020874},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4022877812385559},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3727259337902069},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3443220257759094},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.5152/eurjrheum.2017.17066","doi":"https://doi.org/10.5152/eurjrheum.2017.17066","is_oa":true,"landing_page_url":"https://doi.org/10.5152/eurjrheum.2017.17066","pdf_url":"http://eurjrheumatol.org/en/aneurysm-of-the-ascending-aorta-in-systemic-lupus-erythematosus-case-report-and-review-of-the-literature-1617893","source":{"id":"https://openalex.org/S2764417355","display_name":"European Journal of Rheumatology","issn_l":"2147-9720","issn":["2147-9720","2148-4279"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-20","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4310318309","host_organization_name":"AVES Yayincilik","host_organization_lineage":["https://openalex.org/P4310318309"],"host_organization_lineage_names":["AVES Yayincilik"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Rheumatology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4325536","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5473449","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5473449","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5473449","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur J Rheumatol","raw_type":"Text"},{"id":"pmid:28638687","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28638687","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of rheumatology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5152/eurjrheum.2017.17066","doi":"https://doi.org/10.5152/eurjrheum.2017.17066","is_oa":true,"landing_page_url":"https://doi.org/10.5152/eurjrheum.2017.17066","pdf_url":"http://eurjrheumatol.org/en/aneurysm-of-the-ascending-aorta-in-systemic-lupus-erythematosus-case-report-and-review-of-the-literature-1617893","source":{"id":"https://openalex.org/S2764417355","display_name":"European Journal of Rheumatology","issn_l":"2147-9720","issn":["2147-9720","2148-4279"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","ki-jl-1","norway-1","poland-20","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4310318309","host_organization_name":"AVES Yayincilik","host_organization_lineage":["https://openalex.org/P4310318309"],"host_organization_lineage_names":["AVES Yayincilik"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Rheumatology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320327899","display_name":"Sociedad Espa\u00f1ola de Reumatolog\u00eda","ror":"https://ror.org/01fm69p79"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2626515639.pdf","grobid_xml":"https://content.openalex.org/works/W2626515639.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1512910345","https://openalex.org/W1897788786","https://openalex.org/W1982229143","https://openalex.org/W1982548943","https://openalex.org/W2017800434","https://openalex.org/W2027675367","https://openalex.org/W2045454448","https://openalex.org/W2059402361","https://openalex.org/W2113289019","https://openalex.org/W2113690500","https://openalex.org/W2129386868","https://openalex.org/W2155248983","https://openalex.org/W2160618519","https://openalex.org/W2166684032","https://openalex.org/W2169620827","https://openalex.org/W2316323229","https://openalex.org/W2338545097"],"related_works":["https://openalex.org/W73858461","https://openalex.org/W2103895530","https://openalex.org/W2063029106","https://openalex.org/W2113690500","https://openalex.org/W2053673741","https://openalex.org/W2610969822","https://openalex.org/W4384207555","https://openalex.org/W2045454448","https://openalex.org/W1857421430","https://openalex.org/W2136665493"],"abstract_inverted_index":{"Cardiovascular":[0],"manifestations":[1],"in":[2,102],"patients":[3,103],"with":[4,24,37,104],"systemic":[5],"lupus":[6],"erythematosus":[7],"(SLE)":[8],"are":[9],"common,":[10],"but":[11],"aortic":[12,83,100],"aneurysm":[13,42,56],"formation":[14],"is":[15,72],"rare.":[16],"We":[17],"present":[18],"a":[19,25,79],"63-year-old":[20],"male":[21],"SLE":[22],"patient":[23,86],"two-year":[26],"history":[27],"of":[28,43,54,74,93,98],"skin":[29],"lesions,":[30],"leucopenia,":[31],"pericarditis,":[32],"mitral":[33],"valve":[34],"vegetations":[35],"consistent":[36],"Liebman-Sacks":[38],"endocarditis,":[39],"and":[40,64,85,96],"an":[41],"the":[44,55,91],"ascending":[45],"aorta,":[46],"which":[47],"was":[48],"successfully":[49],"repaired":[50],"surgically.":[51],"Histologic":[52],"examination":[53],"showed":[57],"medial":[58],"cystic":[59],"degeneration,":[60],"smooth":[61],"muscle":[62],"necrosis,":[63],"mild":[65],"adventitial":[66],"perivascular":[67],"lymphocytic":[68],"aggregates.":[69],"This":[70],"histology":[71],"typical":[73],"thoracic":[75,99],"aneurysms":[76,101],"that":[77],"carry":[78],"high":[80],"risk":[81],"for":[82],"dissection":[84],"death.":[87],"The":[88],"case":[89],"highlights":[90],"importance":[92],"early":[94],"detection":[95],"treatment":[97],"SLE.":[105]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2017-06-23T00:00:00"}