{"id":"https://openalex.org/W2624898548","doi":"https://doi.org/10.1093/pm/pnx132","title":"Efficacy, Safety, and Feasibility of the Morphine Microdose Method in Community-Based Clinics","display_name":"Efficacy, Safety, and Feasibility of the Morphine Microdose Method in Community-Based Clinics","publication_year":2017,"publication_date":"2017-05-02","ids":{"openalex":"https://openalex.org/W2624898548","doi":"https://doi.org/10.1093/pm/pnx132","mag":"2624898548","pmid":"https://pubmed.ncbi.nlm.nih.gov/29016893","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6454799"},"language":"en","primary_location":{"id":"doi:10.1093/pm/pnx132","doi":"https://doi.org/10.1093/pm/pnx132","is_oa":false,"landing_page_url":"https://doi.org/10.1093/pm/pnx132","pdf_url":null,"source":{"id":"https://openalex.org/S191903559","display_name":"Pain Medicine","issn_l":"1526-2375","issn":["1526-2375","1526-4637"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pain Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6454799","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050766397","display_name":"Denise M Wilkes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Denise M Wilkes","raw_affiliation_strings":["Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas","Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas","institution_ids":["https://openalex.org/I55302922"]},{"raw_affiliation_string":"Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080769312","display_name":"Susan J Orillosa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan J Orillosa","raw_affiliation_strings":["Space City Pain Specialist-Baytown, Baytown, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Space City Pain Specialist-Baytown, Baytown, Texas","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056299464","display_name":"Erik C. Hustak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erik C Hustak","raw_affiliation_strings":["Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011999475","display_name":"Courtney Williams","orcid":"https://orcid.org/0000-0002-4630-112X","observed_orcids":["https://orcid.org/0000-0002-4630-112X"]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Courtney G Williams","raw_affiliation_strings":["Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112581912","display_name":"Gulshan R. Doulatram","orcid":"https://orcid.org/0000-0002-7725-8574","observed_orcids":["https://orcid.org/0000-0002-7725-8574"]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gulshan R Doulatram","raw_affiliation_strings":["Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108633196","display_name":"Daneshvari R. Solanki","orcid":"https://orcid.org/0009-0007-7621-4426","observed_orcids":["https://orcid.org/0009-0007-7621-4426"]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daneshvari R Solanki","raw_affiliation_strings":["Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Pain Medicine, University of Texas Medical Branch, Galveston, Texas","institution_ids":["https://openalex.org/I55302922"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Eduardo A Garcia","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eduardo A Garcia","raw_affiliation_strings":["Space City Pain Specialist-Clear Lake, Webster, Texas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Space City Pain Specialist-Clear Lake, Webster, Texas","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110468662","display_name":"Li-Yen Mae Huang","orcid":"https://orcid.org/0000-0003-0225-2810","observed_orcids":["https://orcid.org/0000-0003-0225-2810"]},"institutions":[{"id":"https://openalex.org/I55302922","display_name":"The University of Texas Medical Branch at Galveston","ror":"https://ror.org/016tfm930","country_code":"US","type":"education","lineage":["https://openalex.org/I55302922"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Li-Yen M Huang","raw_affiliation_strings":["Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas, USA","institution_ids":["https://openalex.org/I55302922"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5050766397"],"corresponding_institution_ids":["https://openalex.org/I55302922"],"apc_list":{"value":5036,"currency":"USD","value_usd":5036},"apc_paid":null,"fwci":0.818,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.74035798,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"19","issue":"9","first_page":"1782","last_page":"1789"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intrathecal-morphine","display_name":"intrathecal morphine","score":0.9800000190734863},{"id":"https://openalex.org/keywords/chronic-non-cancer-pain","display_name":"chronic non-cancer pain","score":0.828000009059906},{"id":"https://openalex.org/keywords/opioid-abstinence","display_name":"opioid abstinence","score":0.8759999871253967},{"id":"https://openalex.org/keywords/dose-escalation","display_name":"dose escalation","score":0.6890000104904175},{"id":"https://openalex.org/keywords/monotherapy","display_name":"monotherapy","score":0.593999981880188},{"id":"https://openalex.org/keywords/polypharmacy","display_name":"polypharmacy","score":0.8019999861717224},{"id":"https://openalex.org/keywords/pain-scores","display_name":"pain scores","score":0.7289999723434448},{"id":"https://openalex.org/keywords/opioid-side-effects","display_name":"opioid side effects","score":0.7070000171661377},{"id":"https://openalex.org/keywords/outpatient-pain-management","display_name":"outpatient pain management","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C2780913584","wikidata":"https://www.wikidata.org/wiki/Q6839483","display_name":"MicroDose","level":2,"score":0.993747353553772},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9124822020530701},{"id":"https://openalex.org/C2777389121","wikidata":"https://www.wikidata.org/wiki/Q81225","display_name":"Morphine","level":2,"score":0.7100635766983032},{"id":"https://openalex.org/C2781063702","wikidata":"https://www.wikidata.org/wiki/Q427523","display_name":"Opioid","level":3,"score":0.5740301012992859},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.4688728153705597},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.43380579352378845},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26147639751434326},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000701","descriptor_name":"Analgesics, Opioid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007278","descriptor_name":"Injections, Spinal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009020","descriptor_name":"Morphine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059350","descriptor_name":"Chronic Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D059408","descriptor_name":"Pain Management","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/pm/pnx132","doi":"https://doi.org/10.1093/pm/pnx132","is_oa":false,"landing_page_url":"https://doi.org/10.1093/pm/pnx132","pdf_url":null,"source":{"id":"https://openalex.org/S191903559","display_name":"Pain Medicine","issn_l":"1526-2375","issn":["1526-2375","1526-4637"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pain Medicine","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5442340","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6454799","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6454799","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6454799","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pain Med","raw_type":"Text"},{"id":"pmid:29016893","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29016893","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pain medicine (Malden, Mass.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5442340","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6454799","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1279668552","display_name":"Neuronal-Glia Interactions in Trigeminal Ganglia as a Basis for Future Therapy","funder_award_id":"R01DE017813","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G3222227421","display_name":"Injury-Induced Plasticity of P2X Receptor Function","funder_award_id":"R01NS030045","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W89545600","https://openalex.org/W149122356","https://openalex.org/W164071057","https://openalex.org/W1503032446","https://openalex.org/W1546160062","https://openalex.org/W1552500658","https://openalex.org/W1825985006","https://openalex.org/W2005906866","https://openalex.org/W2032079591","https://openalex.org/W2077313760","https://openalex.org/W2100956576","https://openalex.org/W2114975159","https://openalex.org/W2118096395","https://openalex.org/W2132202616","https://openalex.org/W2152791044","https://openalex.org/W3049373895","https://openalex.org/W6677432360"],"related_works":["https://openalex.org/W2139756357","https://openalex.org/W89545600","https://openalex.org/W4327610709","https://openalex.org/W1515840181","https://openalex.org/W2111194101","https://openalex.org/W4311106838","https://openalex.org/W4413104692","https://openalex.org/W2019361433","https://openalex.org/W2201852986","https://openalex.org/W2980070712"],"abstract_inverted_index":{"Objectives:":[0],"The":[1,31,142,199],"goal":[2],"of":[3,11,41,48,58,81,101,144,201,219],"this":[4],"study":[5],"was":[6,165,204,224],"to":[7,180],"assess":[8],"the":[9,12,99,230],"success":[10],"morphine":[13,32,52,76,153],"microdose":[14,33,108,154,178,185,222],"method":[15,34],"in":[16,169,229],"a":[17,36,46,107,166,208],"community":[18],"pain":[19,88,94,131,171],"clinic":[20,89],"setting":[21],"by":[22,45,206],"monitoring":[23],"follow-up":[24],"frequency,":[25],"dose":[26,127],"escalation,":[27],"and":[28,74,86,110,120,137,194,213,227],"monotherapy/polytherapy":[29],"ratio.":[30],"involves":[35],"pretrial":[37],"reduction":[38,168],"or":[39],"elimination":[40],"systemic":[42,196],"opioids":[43],"followed":[44],"period":[47],"abstinence.":[49],"Intrathecal":[50],"(IT)":[51],"is":[53,68],"then":[54,69],"started":[55],"at":[56],"doses":[57,216],"less":[59],"than":[60],"0.2":[61],"mg":[62],"per":[63],"day.":[64],"Systemic":[65],"opioid":[66],"abstinence":[67],"continued":[70],"after":[71,184],"pump":[72,114],"implant":[73],"IT":[75,113,125,202],"monotherapy.":[77,155],"Design:":[78],"Retrospective":[79],"review":[80],"medical":[82],"records.":[83],"Setting:":[84],"Private":[85],"academic":[87],"practices.":[90],"Subjects:":[91],"Chronic":[92],"noncancer":[93],"patients.":[95],"Methods:":[96],"We":[97],"reviewed":[98],"charts":[100],"60":[102],"patients":[103,145,157],"who":[104],"had":[105,111],"completed":[106],"regimen":[109],"an":[112],"implanted":[115],"between":[116],"June":[117],"11,":[118,122],"2008,":[119],"October":[121],"2014.":[123],"During":[124],"therapy,":[126],"change":[128],"over":[129],"time,":[130],"scores,":[132,172],"side":[133,197],"effects,":[134],"max":[135],"dose,":[136],"duration":[138],"were":[139,148],"recorded.":[140],"Results:":[141],"majority":[143],"(35/60,":[146],"58%)":[147],"successfully":[149],"managed":[150],"solely":[151],"on":[152],"These":[156],"did":[158],"not":[159],"require":[160],"additional":[161],"oral":[162],"therapy.":[163,186],"There":[164],"significant":[167],"mean":[170],"from":[173],"7.4":[174],"\u00b1":[175,182],"0.32":[176],"before":[177],"therapy":[179,189,203,223],"4.8":[181],"0.3":[183],"Conclusions:":[187],"Microdose":[188],"achieved":[190],"analgesia,":[191],"improved":[192],"safety,":[193],"avoided":[195],"effects.":[198],"safety":[200],"increased":[205],"using":[207],"lower":[209,214],"concentration":[210],"(2":[211],"mg/mL)":[212],"daily":[215],"(<3":[217],"mg/d)":[218],"morphine.":[220],"Furthermore,":[221],"feasible,":[225],"safe,":[226],"cost-effective":[228],"outpatient":[231],"setting.":[232]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-06-23T00:00:00"}