{"id":"https://openalex.org/W2623945663","doi":"https://doi.org/10.1016/j.cmet.2017.05.012","title":"Treg Cells Survive and Thrive in Inhospitable Environments","display_name":"Treg Cells Survive and Thrive in Inhospitable Environments","publication_year":2017,"publication_date":"2017-06-01","ids":{"openalex":"https://openalex.org/W2623945663","doi":"https://doi.org/10.1016/j.cmet.2017.05.012","mag":"2623945663","pmid":"https://pubmed.ncbi.nlm.nih.gov/28591629"},"language":"en","primary_location":{"id":"doi:10.1016/j.cmet.2017.05.012","doi":"https://doi.org/10.1016/j.cmet.2017.05.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cmet.2017.05.012","pdf_url":"http://www.cell.com/article/S1550413117303017/pdf","source":{"id":"https://openalex.org/S177533077","display_name":"Cell Metabolism","issn_l":"1550-4131","issn":["1550-4131","1932-7420"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1550413117303017/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078654052","display_name":"Katarzyna M. Grzes","orcid":"https://orcid.org/0000-0002-5158-1111","observed_orcids":["https://orcid.org/0000-0002-5158-1111"]},"institutions":[{"id":"https://openalex.org/I4210164321","display_name":"Max Planck Institute of Immunobiology and Epigenetics","ror":"https://ror.org/058xzat49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210164321"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katarzyna M. Grzes","raw_affiliation_strings":["Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany","institution_ids":["https://openalex.org/I4210164321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019374242","display_name":"Cameron S. Field","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164321","display_name":"Max Planck Institute of Immunobiology and Epigenetics","ror":"https://ror.org/058xzat49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210164321"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Cameron S. Field","raw_affiliation_strings":["Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany","institution_ids":["https://openalex.org/I4210164321"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085815766","display_name":"Edward J. Pearce","orcid":"https://orcid.org/0000-0003-1001-9656","observed_orcids":["https://orcid.org/0000-0003-1001-9656"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210164321","display_name":"Max Planck Institute of Immunobiology and Epigenetics","ror":"https://ror.org/058xzat49","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210164321"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Edward J. Pearce","raw_affiliation_strings":["Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany. Electronic address: pearceed@ie-freiburg.mpg.de","Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany","Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany. Electronic address: pearceed@ie-freiburg.mpg.de","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210164321"]},{"raw_affiliation_string":"Department of Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany","institution_ids":["https://openalex.org/I4210164321"]},{"raw_affiliation_string":"Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany","institution_ids":["https://openalex.org/I161046081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5085815766"],"corresponding_institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210164321"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":0.4752,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.5899668,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"25","issue":"6","first_page":"1213","last_page":"1215"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cd4-foxp3-t-cells","display_name":"CD4+ Foxp3+ T cells","score":0.9670000076293945},{"id":"https://openalex.org/keywords/metabolic-adaptation","display_name":"metabolic adaptation","score":0.7099999785423279},{"id":"https://openalex.org/keywords/immune-regulation","display_name":"immune regulation","score":0.7490000128746033},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.4410000145435333},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.8980000019073486}],"concepts":[{"id":"https://openalex.org/C2776917539","wikidata":"https://www.wikidata.org/wiki/Q1497481","display_name":"Failure to thrive","level":2,"score":0.674460768699646},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38435888290405273},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3677358031272888},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3316061496734619},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32747066020965576},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1575884222984314}],"mesh":[{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015496","descriptor_name":"CD4-Positive T-Lymphocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019344","descriptor_name":"Lactic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050378","descriptor_name":"T-Lymphocytes, Regulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.cmet.2017.05.012","doi":"https://doi.org/10.1016/j.cmet.2017.05.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cmet.2017.05.012","pdf_url":"http://www.cell.com/article/S1550413117303017/pdf","source":{"id":"https://openalex.org/S177533077","display_name":"Cell Metabolism","issn_l":"1550-4131","issn":["1550-4131","1932-7420"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Metabolism","raw_type":"journal-article"},{"id":"pmid:28591629","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28591629","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell metabolism","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.cmet.2017.05.012","doi":"https://doi.org/10.1016/j.cmet.2017.05.012","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.cmet.2017.05.012","pdf_url":"http://www.cell.com/article/S1550413117303017/pdf","source":{"id":"https://openalex.org/S177533077","display_name":"Cell Metabolism","issn_l":"1550-4131","issn":["1550-4131","1932-7420"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315673","host_organization_name":"Cell Press","host_organization_lineage":["https://openalex.org/P4310315673","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Cell Press","Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Metabolism","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2623945663.pdf"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1768577517","https://openalex.org/W2075372904","https://openalex.org/W2079999658","https://openalex.org/W2151328705","https://openalex.org/W2157739158","https://openalex.org/W2164115182","https://openalex.org/W2503407514","https://openalex.org/W2529711900","https://openalex.org/W2587363764","https://openalex.org/W2607103422","https://openalex.org/W4294138012"],"related_works":["https://openalex.org/W2521111409","https://openalex.org/W2607103422","https://openalex.org/W2994802995","https://openalex.org/W2791931497","https://openalex.org/W4323045598","https://openalex.org/W4399316280","https://openalex.org/W2560154228","https://openalex.org/W2538957385","https://openalex.org/W2579277915","https://openalex.org/W2964131857"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-06-15T00:00:00"}