{"id":"https://openalex.org/W2620915022","doi":"https://doi.org/10.1002/psp4.12213","title":"PharmML in Action: an Interoperable Language for Modeling and Simulation","display_name":"PharmML in Action: an Interoperable Language for Modeling and Simulation","publication_year":2017,"publication_date":"2017-06-02","ids":{"openalex":"https://openalex.org/W2620915022","doi":"https://doi.org/10.1002/psp4.12213","mag":"2620915022","pmid":"https://pubmed.ncbi.nlm.nih.gov/28575551","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5658288"},"language":"en","primary_location":{"id":"doi:10.1002/psp4.12213","doi":"https://doi.org/10.1002/psp4.12213","is_oa":true,"landing_page_url":"https://doi.org/10.1002/psp4.12213","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/psp4.12213","source":{"id":"https://openalex.org/S4210231731","display_name":"CPT Pharmacometrics & Systems Pharmacology","issn_l":"2163-8306","issn":["2163-8306"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CPT: Pharmacometrics & Systems Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/psp4.12213","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075784923","display_name":"Roberto Bizzotto","orcid":"https://orcid.org/0000-0002-8251-1730","observed_orcids":["https://orcid.org/0000-0002-8251-1730"]},"institutions":[{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R Bizzotto","raw_affiliation_strings":["CNR Institute of Neuroscience, Padua, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CNR Institute of Neuroscience, Padua, Italy","institution_ids":["https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055845414","display_name":"Emmanuelle Comets","orcid":"https://orcid.org/0000-0002-9150-9886","observed_orcids":["https://orcid.org/0000-0002-9150-9886"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210091437","display_name":"Sorbonne Paris Cit\u00e9","ror":"https://ror.org/001z21q04","country_code":"FR","type":"other","lineage":["https://openalex.org/I204730241","https://openalex.org/I4210091437"]},{"id":"https://openalex.org/I4210116274","display_name":"CIC Rennes","ror":"https://ror.org/02baj6743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I4210105774","https://openalex.org/I4210116274","https://openalex.org/I4210155724","https://openalex.org/I56067802"]},{"id":"https://openalex.org/I4387154366","display_name":"Universit\u00e9 Paris Diderot","ror":"https://ror.org/02n7qrg46","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387154366"]},{"id":"https://openalex.org/I4387156044","display_name":"Infection, Anti-microbiens, Mod\u00e9lisation, Evolution","ror":"https://ror.org/05hqep952","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4387156044"]},{"id":"https://openalex.org/I56067802","display_name":"Universit\u00e9 de Rennes","ror":"https://ror.org/015m7wh34","country_code":"FR","type":"education","lineage":["https://openalex.org/I56067802"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"E Comets","raw_affiliation_strings":["INSERM CIC 1414, Universit\u00e9 de Rennes 1 Rennes France","INSERM, IAME, UMR 1137, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9 Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM CIC 1414, Universit\u00e9 de Rennes 1 Rennes France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210116274","https://openalex.org/I56067802"]},{"raw_affiliation_string":"INSERM, IAME, UMR 1137, Universit\u00e9 Paris Diderot, Sorbonne Paris Cit\u00e9 Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210091437","https://openalex.org/I4387154366","https://openalex.org/I4387156044"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111944563","display_name":"Garth A. M. Smith","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Smith","raw_affiliation_strings":["Scientific Computing Group, Cyprotex Discovery Ltd, Cheshire, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific Computing Group, Cyprotex Discovery Ltd, Cheshire, United Kingdom","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079697004","display_name":"Florent Yvon","orcid":"https://orcid.org/0000-0002-6025-3590","observed_orcids":["https://orcid.org/0000-0002-6025-3590"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F Yvon","raw_affiliation_strings":["EMBL-EBI, Wellcome Genome Campus, Hinxton, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBL-EBI, Wellcome Genome Campus, Hinxton, United Kingdom","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061487427","display_name":"Niels Rode Kristensen","orcid":"https://orcid.org/0000-0001-8582-6298","observed_orcids":["https://orcid.org/0000-0001-8582-6298"]},"institutions":[{"id":"https://openalex.org/I189090001","display_name":"Novo Nordisk (Denmark)","ror":"https://ror.org/0435rc536","country_code":"DK","type":"company","lineage":["https://openalex.org/I189090001","https://openalex.org/I2801134892","https://openalex.org/I4210159963"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"NR Kristensen","raw_affiliation_strings":["Novo Nordisk, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novo Nordisk, Denmark","institution_ids":["https://openalex.org/I189090001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024940011","display_name":"Maciej J. Swat","orcid":"https://orcid.org/0000-0003-1721-9036","observed_orcids":["https://orcid.org/0000-0003-1721-9036"]},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]},{"id":"https://openalex.org/I4210161181","display_name":"Simcyp (United Kingdom)","ror":"https://ror.org/02j65kc59","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210161181"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"MJ Swat","raw_affiliation_strings":["EMBL-EBI, Wellcome Genome Campus, Hinxton, United Kingdom","Simcyp Limited (a Certara company), Sheffield, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"EMBL-EBI, Wellcome Genome Campus, Hinxton, United Kingdom","institution_ids":["https://openalex.org/I1303153112"]},{"raw_affiliation_string":"Simcyp Limited (a Certara company), Sheffield, United Kingdom","institution_ids":["https://openalex.org/I4210161181"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5055845414"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210091437","https://openalex.org/I4210116274","https://openalex.org/I4387154366","https://openalex.org/I4387156044","https://openalex.org/I56067802"],"apc_list":{"value":4140,"currency":"USD","value_usd":4140},"apc_paid":{"value":4140,"currency":"USD","value_usd":4140},"fwci":1.4747,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.81431546,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"6","issue":"10","first_page":"651","last_page":"665"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.4147999882698059,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.4147999882698059,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.2328999936580658,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13286","display_name":"Modeling and Simulation Systems","score":0.07289999723434448,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interoperability","display_name":"interoperability","score":0.8270000219345093},{"id":"https://openalex.org/keywords/nonlinear-mixed-effects-models","display_name":"nonlinear mixed-effects models","score":0.8629999756813049},{"id":"https://openalex.org/keywords/pharmacometrics","display_name":"pharmacometrics","score":0.765999972820282},{"id":"https://openalex.org/keywords/nonlinear-regression","display_name":"nonlinear regression","score":0.6050000190734863},{"id":"https://openalex.org/keywords/multivariate-regression","display_name":"multivariate regression","score":0.9570000171661377},{"id":"https://openalex.org/keywords/model-exchange","display_name":"model exchange","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.742415726184845},{"id":"https://openalex.org/C2780598303","wikidata":"https://www.wikidata.org/wiki/Q65921492","display_name":"Flexibility (engineering)","level":2,"score":0.5743721723556519},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.5561401844024658},{"id":"https://openalex.org/C20136886","wikidata":"https://www.wikidata.org/wiki/Q749647","display_name":"Interoperability","level":2,"score":0.5428142547607422},{"id":"https://openalex.org/C8797682","wikidata":"https://www.wikidata.org/wiki/Q2115","display_name":"XML","level":2,"score":0.4830261170864105},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.47884202003479004},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.46546339988708496},{"id":"https://openalex.org/C137293760","wikidata":"https://www.wikidata.org/wiki/Q3621696","display_name":"Language model","level":2,"score":0.42572835087776184},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.42460140585899353},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35433337092399597},{"id":"https://openalex.org/C204321447","wikidata":"https://www.wikidata.org/wiki/Q30642","display_name":"Natural language processing","level":1,"score":0.3361971974372864},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.31702059507369995},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.14548948407173157},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.13448196649551392},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.11911264061927795},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017711","descriptor_name":"Nonlinear Dynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1002/psp4.12213","doi":"https://doi.org/10.1002/psp4.12213","is_oa":true,"landing_page_url":"https://doi.org/10.1002/psp4.12213","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/psp4.12213","source":{"id":"https://openalex.org/S4210231731","display_name":"CPT Pharmacometrics & Systems Pharmacology","issn_l":"2163-8306","issn":["2163-8306"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CPT: Pharmacometrics & Systems Pharmacology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4575105","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5658288","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5658288","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5658288","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CPT Pharmacometrics Syst Pharmacol","raw_type":"Text"},{"id":"pmid:28575551","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28575551","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CPT: pharmacometrics & systems pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-01637190v1","doi":null,"is_oa":false,"landing_page_url":"https://univ-rennes.hal.science/hal-01637190","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"CPT: Pharmacometrics and Systems Pharmacology, 2017, 6 (10), pp.651-665. ⟨10.1002/psp4.12213⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:94dc88a8-cee7-4e67-a4aa-d3f5f8340457","doi":null,"is_oa":true,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:94dc88a8-cee7-4e67-a4aa-d3f5f8340457","pdf_url":null,"source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Symplectic Elements","raw_type":"Journal article"}],"best_oa_location":{"id":"doi:10.1002/psp4.12213","doi":"https://doi.org/10.1002/psp4.12213","is_oa":true,"landing_page_url":"https://doi.org/10.1002/psp4.12213","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/psp4.12213","source":{"id":"https://openalex.org/S4210231731","display_name":"CPT Pharmacometrics & Systems Pharmacology","issn_l":"2163-8306","issn":["2163-8306"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CPT: Pharmacometrics & Systems Pharmacology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1073258374","display_name":null,"funder_award_id":"FP7/20072013","funder_id":"https://openalex.org/F4320314178","funder_display_name":"European Federation of Pharmaceutical Industries and Associations"},{"id":"https://openalex.org/G2516573747","display_name":"Drug Disease Model Resources","funder_award_id":"115156","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3207356259","display_name":null,"funder_award_id":"2007\u20132013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G393177772","display_name":null,"funder_award_id":"FP7 2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5702163051","display_name":null,"funder_award_id":"FP7/2007","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320314178","display_name":"European Federation of Pharmaceutical Industries and Associations","ror":"https://ror.org/00g1x4v36"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2620915022.pdf","grobid_xml":"https://content.openalex.org/works/W2620915022.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W3058535","https://openalex.org/W1500560370","https://openalex.org/W1517555081","https://openalex.org/W1542069658","https://openalex.org/W1546727052","https://openalex.org/W1550111394","https://openalex.org/W1626014497","https://openalex.org/W1802153259","https://openalex.org/W1996557469","https://openalex.org/W2000741779","https://openalex.org/W2008030496","https://openalex.org/W2028916585","https://openalex.org/W2029064284","https://openalex.org/W2035387023","https://openalex.org/W2041228025","https://openalex.org/W2065010965","https://openalex.org/W2069076431","https://openalex.org/W2089137624","https://openalex.org/W2107062718","https://openalex.org/W2114124738","https://openalex.org/W2116310353","https://openalex.org/W2123783513","https://openalex.org/W2125624587","https://openalex.org/W2136853888","https://openalex.org/W2140410981","https://openalex.org/W2140611297","https://openalex.org/W2150908245","https://openalex.org/W2156353972","https://openalex.org/W2160751597","https://openalex.org/W2228342512","https://openalex.org/W2329094530","https://openalex.org/W2336451435","https://openalex.org/W2336854758","https://openalex.org/W2488433815","https://openalex.org/W2799294372","https://openalex.org/W4238063882","https://openalex.org/W4245221027"],"related_works":["https://openalex.org/W1500560370","https://openalex.org/W2950199458","https://openalex.org/W3084000256","https://openalex.org/W1546562547","https://openalex.org/W7131247683","https://openalex.org/W2560149341","https://openalex.org/W1860319071","https://openalex.org/W3114318704","https://openalex.org/W4404473838","https://openalex.org/W6920707534"],"abstract_inverted_index":{"PharmML":[0],"is":[1],"an":[2,44],"XML-based":[3],"exchange":[4],"format":[5],"created":[6],"with":[7,58],"a":[8,20],"focus":[9],"on":[10,54],"nonlinear":[11,36],"mixed-effect":[12],"(NLME)":[13],"models":[14,31],"used":[15],"in":[16],"pharmacometrics,":[17],"but":[18],"providing":[19],"very":[21],"general":[22],"framework":[23],"that":[24],"also":[25],"allows":[26],"describing":[27],"mathematical":[28],"and":[29,37,60,66],"statistical":[30],"such":[32],"as":[33],"single-subject":[34],"or":[35],"multivariate":[38],"regression":[39],"models.":[40],"This":[41],"tutorial":[42],"provides":[43],"overview":[45],"of":[46,49],"the":[47],"structure":[48],"this":[50],"language,":[51],"brief":[52],"suggestions":[53],"how":[55],"to":[56],"work":[57],"it,":[59],"use":[61],"cases":[62],"demonstrating":[63],"its":[64],"power":[65],"flexibility.":[67]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-06-09T00:00:00"}