{"id":"https://openalex.org/W2620739596","doi":"https://doi.org/10.1016/s1569-1993(17)30449-6","title":"85 Decreased circulating IL-2 and dehydroepiandrosterone in adult cystic fibrosis patients infected with Burkholderia cepacia complex","display_name":"85 Decreased circulating IL-2 and dehydroepiandrosterone in adult cystic fibrosis patients infected with Burkholderia cepacia complex","publication_year":2017,"publication_date":"2017-06-01","ids":{"openalex":"https://openalex.org/W2620739596","doi":"https://doi.org/10.1016/s1569-1993(17)30449-6","mag":"2620739596"},"language":"en","primary_location":{"id":"doi:10.1016/s1569-1993(17)30449-6","doi":"https://doi.org/10.1016/s1569-1993(17)30449-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","pdf_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","source":{"id":"https://openalex.org/S147774598","display_name":"Journal of Cystic Fibrosis","issn_l":"1569-1993","issn":["1569-1993","1873-5010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cystic Fibrosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039131110","display_name":"\u0413. \u0412. \u0428\u043c\u0430\u0440\u0438\u043d\u0430","orcid":"https://orcid.org/0000-0003-4851-8987","observed_orcids":["https://orcid.org/0000-0003-4851-8987"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"G. Shmarina","raw_affiliation_strings":["Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059755413","display_name":"Daria A. Pukhalskaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"D. Pukhalskaya","raw_affiliation_strings":["Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076991673","display_name":"Nataliya Y. Kashirskaya","orcid":"https://orcid.org/0000-0003-0503-6371","observed_orcids":["https://orcid.org/0000-0003-0503-6371"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N.Y. Kashirskaya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108774210","display_name":"Stanislav Aleksandrovich Krasovsky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"S.A. Krasovsky","raw_affiliation_strings":["Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032575161","display_name":"Maria Usacheva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M.V. Usacheva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027049859","display_name":"E. Amelina","orcid":"https://orcid.org/0000-0002-5356-9415","observed_orcids":["https://orcid.org/0000-0002-5356-9415"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"E.L. Amelina","raw_affiliation_strings":["Karolinska Institutet, Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Stockholm, Sweden;","Karolinska Institutet, Stockholm CF Center, Karolinska University Hospital Huddinge, Stockholm, Sweden;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Stockholm, Sweden;","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Karolinska Institutet, Stockholm CF Center, Karolinska University Hospital Huddinge, Stockholm, Sweden;","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041996018","display_name":"Vladimir Alioshkin","orcid":"https://orcid.org/0000-0001-6163-6342","observed_orcids":["https://orcid.org/0000-0001-6163-6342"]},"institutions":[{"id":"https://openalex.org/I1335113835","display_name":"Karolinska University Hospital","ror":"https://ror.org/00m8d6786","country_code":"SE","type":"healthcare","lineage":["https://openalex.org/I1335113835"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"V. Alioshkin","raw_affiliation_strings":["Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden","Karolinska Institutet, Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Stockholm, Sweden;","Karolinska Institutet, Stockholm CF Center, Karolinska University Hospital Huddinge, Stockholm, Sweden;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Karolinska Institutet, Center for Infectious Medicine, Department of Medicine, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Karolinska Institutet, Division of Pediatrics, Department of Clinical Science, Intervention and Technology, Stockholm, Sweden;","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Karolinska Institutet, Stockholm CF Center, Karolinska University Hospital Huddinge, Stockholm, Sweden;","institution_ids":["https://openalex.org/I1335113835","https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4370,"currency":"USD","value_usd":4370},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10725195,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":null,"first_page":"S86","last_page":"S86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.7699999809265137,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12951","display_name":"Burkholderia infections and melioidosis","score":0.12710000574588776,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.024900000542402267,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/burkholderia-cepacia-complex","display_name":"Burkholderia cepacia complex","score":0.9629999995231628},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.7279999852180481},{"id":"https://openalex.org/keywords/dehydroepiandrosterone","display_name":"dehydroepiandrosterone","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sputum-cytokines","display_name":"sputum cytokines","score":0.9039999842643738},{"id":"https://openalex.org/keywords/il-17a","display_name":"IL-17A","score":0.8980000019073486},{"id":"https://openalex.org/keywords/il-23","display_name":"IL-23","score":1.0},{"id":"https://openalex.org/keywords/th17-cytokines","display_name":"Th17 cytokines","score":0.7580000162124634},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.8659999966621399},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/nontuberculous-mycobacteria","display_name":"nontuberculous mycobacteria","score":0.972000002861023},{"id":"https://openalex.org/keywords/bacterial-lung-infection","display_name":"bacterial lung infection","score":0.675000011920929},{"id":"https://openalex.org/keywords/cytokine-response","display_name":"cytokine response","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.9421505928039551},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.928450345993042},{"id":"https://openalex.org/C2777756538","wikidata":"https://www.wikidata.org/wiki/Q21401468","display_name":"Burkholderia cepacia complex","level":4,"score":0.7869725227355957},{"id":"https://openalex.org/C2780855054","wikidata":"https://www.wikidata.org/wiki/Q135239","display_name":"Burkholderia","level":3,"score":0.6795033812522888},{"id":"https://openalex.org/C2776992908","wikidata":"https://www.wikidata.org/wiki/Q408376","display_name":"Dehydroepiandrosterone","level":4,"score":0.4486100375652313},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41249942779541016},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32459700107574463},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.10814958810806274},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.07765012979507446},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.03870350122451782},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.036257654428482056},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s1569-1993(17)30449-6","doi":"https://doi.org/10.1016/s1569-1993(17)30449-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","pdf_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","source":{"id":"https://openalex.org/S147774598","display_name":"Journal of Cystic Fibrosis","issn_l":"1569-1993","issn":["1569-1993","1873-5010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cystic Fibrosis","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s1569-1993(17)30449-6","doi":"https://doi.org/10.1016/s1569-1993(17)30449-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","pdf_url":"https://doi.org/10.1016/s1569-1993(17)30449-6","source":{"id":"https://openalex.org/S147774598","display_name":"Journal of Cystic Fibrosis","issn_l":"1569-1993","issn":["1569-1993","1873-5010"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cystic Fibrosis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2620739596.pdf","grobid_xml":"https://content.openalex.org/works/W2620739596.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2621018274","https://openalex.org/W2621395276","https://openalex.org/W2620939326","https://openalex.org/W3082229822","https://openalex.org/W4296468682","https://openalex.org/W2118755869","https://openalex.org/W2125242373","https://openalex.org/W2132547736","https://openalex.org/W2128337690","https://openalex.org/W4379980344"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2017-06-09T00:00:00"}