{"id":"https://openalex.org/W2619479477","doi":"https://doi.org/10.1103/physreve.95.052414","title":"Actin growth profile in clathrin-mediated endocytosis","display_name":"Actin growth profile in clathrin-mediated endocytosis","publication_year":2017,"publication_date":"2017-05-23","ids":{"openalex":"https://openalex.org/W2619479477","doi":"https://doi.org/10.1103/physreve.95.052414","mag":"2619479477","pmid":"https://pubmed.ncbi.nlm.nih.gov/28618637","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5792084"},"language":"en","primary_location":{"id":"doi:10.1103/physreve.95.052414","doi":"https://doi.org/10.1103/physreve.95.052414","is_oa":false,"landing_page_url":"https://doi.org/10.1103/physreve.95.052414","pdf_url":null,"source":{"id":"https://openalex.org/S4210235286","display_name":"Physical review. E","issn_l":"2470-0045","issn":["2470-0045","2470-0053","2470-0061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical Review E","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5792084","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045635433","display_name":"Dennis J. Tweten","orcid":"https://orcid.org/0000-0002-7661-2324","observed_orcids":["https://orcid.org/0000-0002-7661-2324"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. J. Tweten","raw_affiliation_strings":["Department of Mechanical Engineering, Washington University, St. Louis, Missouri 63130, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Washington University, St. Louis, Missouri 63130, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045394358","display_name":"Philip V. Bayly","orcid":"https://orcid.org/0000-0003-4303-0704","observed_orcids":["https://orcid.org/0000-0003-4303-0704"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. V. Bayly","raw_affiliation_strings":["Department of Mechanical Engineering, Washington University, St. Louis, Missouri 63130, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Washington University, St. Louis, Missouri 63130, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069656520","display_name":"Anders E Carlsson","orcid":"https://orcid.org/0000-0003-2535-8714","observed_orcids":["https://orcid.org/0000-0003-2535-8714"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. E. Carlsson","raw_affiliation_strings":["Department of Physics, Washington University, St. Louis, Missouri 63130, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics, Washington University, St. Louis, Missouri 63130, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":1.5005,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.79062337,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"95","issue":"5","first_page":"052414","last_page":"052414"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.8062000274658203,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.8062000274658203,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.18629999458789825,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clathrin-mediated-endocytosis","display_name":"clathrin-mediated endocytosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/actin-polymerization","display_name":"actin polymerization","score":0.8429999947547913},{"id":"https://openalex.org/keywords/yeast","display_name":"yeast","score":0.5429999828338623},{"id":"https://openalex.org/keywords/membrane-bending","display_name":"membrane bending","score":0.9089999794960022},{"id":"https://openalex.org/keywords/membrane-mechanics","display_name":"membrane mechanics","score":0.9660000205039978},{"id":"https://openalex.org/keywords/continuum-mechanics","display_name":"continuum mechanics","score":0.593999981880188},{"id":"https://openalex.org/keywords/shear-modulus","display_name":"shear modulus","score":0.6970000267028809},{"id":"https://openalex.org/keywords/turgor-pressure","display_name":"turgor pressure","score":0.9279999732971191},{"id":"https://openalex.org/keywords/actin-networks","display_name":"actin networks","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.8553487658500671},{"id":"https://openalex.org/C63162447","wikidata":"https://www.wikidata.org/wiki/Q21100804","display_name":"Clathrin","level":4,"score":0.7317626476287842},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.6079591512680054},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40565037727355957},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4047496020793915},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3787698447704315},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3336043357849121},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20850294828414917},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.07492661476135254},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07095244526863098}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001696","descriptor_name":"Biomechanical Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002473","descriptor_name":"Cell Wall","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002966","descriptor_name":"Clathrin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004548","descriptor_name":"Elasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004705","descriptor_name":"Endocytosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017711","descriptor_name":"Nonlinear Dynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1103/physreve.95.052414","doi":"https://doi.org/10.1103/physreve.95.052414","is_oa":false,"landing_page_url":"https://doi.org/10.1103/physreve.95.052414","pdf_url":null,"source":{"id":"https://openalex.org/S4210235286","display_name":"Physical review. E","issn_l":"2470-0045","issn":["2470-0045","2470-0053","2470-0061"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical Review E","raw_type":"journal-article"},{"id":"pmid:28618637","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28618637","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physical review. E","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4878374","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5792084","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5792084","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5792084","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Phys Rev E","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4878374","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5792084","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2574759652","display_name":"PROTEIN NETWORKS AND FORCE GENERATION IN YEAST ENDOCYTOSIS","funder_award_id":"R01GM107667","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W261495472","https://openalex.org/W608535524","https://openalex.org/W1569063010","https://openalex.org/W1686763784","https://openalex.org/W1965894593","https://openalex.org/W1970247880","https://openalex.org/W1971060242","https://openalex.org/W1985365711","https://openalex.org/W1985660954","https://openalex.org/W1991748656","https://openalex.org/W2001213884","https://openalex.org/W2011844788","https://openalex.org/W2012107438","https://openalex.org/W2019040974","https://openalex.org/W2021607947","https://openalex.org/W2022378428","https://openalex.org/W2023863818","https://openalex.org/W2037766522","https://openalex.org/W2041724231","https://openalex.org/W2042749721","https://openalex.org/W2045415430","https://openalex.org/W2049097378","https://openalex.org/W2049347400","https://openalex.org/W2059571424","https://openalex.org/W2061306397","https://openalex.org/W2071551238","https://openalex.org/W2076623191","https://openalex.org/W2079175432","https://openalex.org/W2082894283","https://openalex.org/W2095541572","https://openalex.org/W2106252068","https://openalex.org/W2108534377","https://openalex.org/W2110179464","https://openalex.org/W2115931003","https://openalex.org/W2121468553","https://openalex.org/W2128104520","https://openalex.org/W2130508789","https://openalex.org/W2138430231","https://openalex.org/W2142083481","https://openalex.org/W2144811436","https://openalex.org/W2147858135","https://openalex.org/W2149374899","https://openalex.org/W2158944498","https://openalex.org/W2164177269","https://openalex.org/W2166435258","https://openalex.org/W2168301459","https://openalex.org/W2171956751","https://openalex.org/W2264936970","https://openalex.org/W2328067599","https://openalex.org/W2339978819","https://openalex.org/W2508179613","https://openalex.org/W2561610176","https://openalex.org/W4319290968"],"related_works":["https://openalex.org/W1965894593","https://openalex.org/W2914692111","https://openalex.org/W2772615199","https://openalex.org/W2586034414","https://openalex.org/W2955379069","https://openalex.org/W7058051700","https://openalex.org/W2909915036","https://openalex.org/W7046889528","https://openalex.org/W2789928888","https://openalex.org/W2053500104"],"abstract_inverted_index":{"Clathrin-mediated":[0],"endocytosis":[1,29],"in":[2,138,179],"yeast":[3],"is":[4,38,184],"driven":[5],"by":[6,75,78],"a":[7,101,117,127],"protein":[8],"patch":[9],"containing":[10],"close":[11],"to":[12,57],"100":[13],"different":[14],"types":[15],"of":[16,24,32,53,89,97,130],"proteins.":[17],"Among":[18],"the":[19,33,50,59,63,68,95,146,150,158,181],"proteins":[20],"are":[21],"5000-10000":[22],"copies":[23],"polymerized":[25],"actin,":[26],"and":[27,105,157],"successful":[28],"requires":[30],"growth":[31,45,55,113,125,137,142,168],"actin":[34,43,54,76,98,112,151],"network.":[35],"Since":[36],"it":[37],"not":[39],"known":[40],"exactly":[41],"how":[42],"network":[44],"drives":[46,62],"endocytosis,":[47],"we":[48,66,93],"calculate":[49],"spatial":[51],"distribution":[52,70],"required":[56,147],"generate":[58],"force":[60,69],"that":[61,71],"process.":[64],"First,":[65],"establish":[67],"must":[72],"be":[73,172],"supplied":[74],"growth,":[77,99],"combining":[79],"membrane-bending":[80],"profiles":[81],"obtained":[82,115],"via":[83,174],"electron":[84],"microscopy":[85],"with":[86,110],"established":[87],"theories":[88],"membrane":[90],"mechanics.":[91],"Next,":[92],"determine":[94],"profile":[96,114,121,143,169],"using":[100],"continuum":[102],"mechanics":[103],"approach":[104],"an":[106,111],"iterative":[107],"procedure":[108],"starting":[109],"from":[116],"linear":[118],"analysis.":[119],"The":[120,167],"has":[122],"fairly":[123],"constant":[124],"outside":[126],"central":[128],"hole":[129],"radius":[131],"45-50":[132],"nm,":[133],"but":[134],"very":[135,163],"little":[136],"this":[139],"hole.":[140],"This":[141],"can":[144,161],"reproduce":[145],"forces":[148],"if":[149],"shear":[152],"modulus":[153],"exceeds":[154],"80":[155],"kPa,":[156],"growing":[159],"filaments":[160],"exert":[162],"large":[164],"polymerization":[165],"forces.":[166],"prediction":[170],"could":[171],"tested":[173],"electron-microscopy":[175],"or":[176],"super-resolution":[177],"experiments":[178],"which":[180],"turgor":[182],"pressure":[183],"suddenly":[185],"turned":[186],"off.":[187]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2017-06-05T00:00:00"}