{"id":"https://openalex.org/W2616619121","doi":null,"title":"The NLRP3 specific inhibitor CP-456,773 potently attenuates crystal-induced kidney fibrosis in vivo","display_name":"The NLRP3 specific inhibitor CP-456,773 potently attenuates crystal-induced kidney fibrosis in vivo","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2616619121","mag":"2616619121"},"language":"en","primary_location":{"id":"pmh:oai:publications.rwth-aachen.de:674537","doi":null,"is_oa":false,"landing_page_url":"https://publications.rwth-aachen.de/record/674537","pdf_url":null,"source":{"id":"https://openalex.org/S4306401362","display_name":"RWTH Publications (RWTH Aachen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I887968799","host_organization_name":"RWTH Aachen University","host_organization_lineage":["https://openalex.org/I887968799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of immunology 46(SI), 1873 (2016). special issue: \"Special Issue: Abstracts of ICI 2016 International Congress of Immunology, 21\u201326 August 2016, Melbourne, Australia\"","raw_type":"info:eu-repo/semantics/conferenceObject"},"volume":null,"type":"conference-paper","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052802894","display_name":"Isis Ludwig\u2010Portugall","orcid":"https://orcid.org/0000-0002-9463-7111","observed_orcids":["https://orcid.org/0000-0002-9463-7111"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Isis Ludwig\u2010Portugall","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9463-7111","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016667606","display_name":"Veit Hornung","orcid":"https://orcid.org/0000-0002-4150-194X","observed_orcids":["https://orcid.org/0000-0002-4150-194X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Veit Hornung","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034969673","display_name":"Michael J. Primiano","orcid":"https://orcid.org/0000-0003-2405-7450","observed_orcids":["https://orcid.org/0000-0003-2405-7450"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael J. Primiano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063825577","display_name":"Bernardo S. Franklin","orcid":"https://orcid.org/0000-0003-2591-9833","observed_orcids":["https://orcid.org/0000-0003-2591-9833"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bernardo S. Franklin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2591-9833","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042963630","display_name":"Parker D. Hall","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Parker Hall","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070273513","display_name":"Gunther Hartmann","orcid":"https://orcid.org/0000-0003-1021-2018","observed_orcids":["https://orcid.org/0000-0003-1021-2018"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gunther Hartmann","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1021-2018","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061966176","display_name":"Ermanila Dhana","orcid":"https://orcid.org/0009-0007-1639-7953","observed_orcids":["https://orcid.org/0009-0007-1639-7953"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ermanila Dhana","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-1639-7953","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009349672","display_name":"Eicke Latz","orcid":"https://orcid.org/0000-0003-1488-5666","observed_orcids":["https://orcid.org/0000-0003-1488-5666"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eicke Latz","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1488-5666","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039567928","display_name":"Beatrix D.G. Evers","orcid":"https://orcid.org/0000-0002-3422-8121","observed_orcids":["https://orcid.org/0000-0002-3422-8121"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Beatrix D.G. Evers","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3422-8121","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071291097","display_name":"Christian Kurts","orcid":"https://orcid.org/0000-0002-6620-2401","observed_orcids":["https://orcid.org/0000-0002-6620-2401"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian Kurts","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6620-2401","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049305761","display_name":"Peter Boor","orcid":"https://orcid.org/0000-0001-9921-4284","observed_orcids":["https://orcid.org/0000-0001-9921-4284","https://orcid.org/0000-0003-3334-5702"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Boor","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9921-4284","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5063294321","display_name":"Eva Bartok","orcid":"https://orcid.org/0000-0003-0556-1950","observed_orcids":["https://orcid.org/0000-0003-0556-1950"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eva Bartok","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0556-1950","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.3136277,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":null,"first_page":"1873","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.7856000065803528,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.7856000065803528,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.046799998730421066,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11139","display_name":"Gout, Hyperuricemia, Uric Acid","score":0.02979999966919422,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nlrp3-inflammasome","display_name":"NLRP3 inflammasome","score":0.9459999799728394},{"id":"https://openalex.org/keywords/renal-fibrosis","display_name":"renal fibrosis","score":0.8389999866485596},{"id":"https://openalex.org/keywords/anti-inflammatory-therapy","display_name":"anti-inflammatory therapy","score":0.5609999895095825},{"id":"https://openalex.org/keywords/renal-inflammation","display_name":"renal inflammation","score":0.3400000035762787}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.7388912439346313},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6690568327903748},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5032748579978943},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.46566155552864075},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3204052448272705},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2737601399421692},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.06524378061294556}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:publications.rwth-aachen.de:674537","doi":null,"is_oa":false,"landing_page_url":"https://publications.rwth-aachen.de/record/674537","pdf_url":null,"source":{"id":"https://openalex.org/S4306401362","display_name":"RWTH Publications (RWTH Aachen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I887968799","host_organization_name":"RWTH Aachen University","host_organization_lineage":["https://openalex.org/I887968799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of immunology 46(SI), 1873 (2016). special issue: \"Special Issue: Abstracts of ICI 2016 International Congress of Immunology, 21\u201326 August 2016, Melbourne, Australia\"","raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"mag:2616619121","doi":null,"is_oa":false,"landing_page_url":"https://publications.rwth-aachen.de/record/674537","pdf_url":null,"source":{"id":"https://openalex.org/S126191069","display_name":"European Journal of Immunology","issn_l":"0014-2980","issn":["0014-2980","1521-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Immunology","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2956071801","https://openalex.org/W2528813222","https://openalex.org/W4391847125","https://openalex.org/W7146847879","https://openalex.org/W2286146897","https://openalex.org/W4226077945","https://openalex.org/W2794051583","https://openalex.org/W2944142046","https://openalex.org/W2593936419","https://openalex.org/W6944129356"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2017-05-26T00:00:00"}