{"id":"https://openalex.org/W2614739628","doi":null,"title":"Identification and characterisation of cat allergens","display_name":"Identification and characterisation of cat allergens","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2614739628","mag":"2614739628"},"language":"en","primary_location":{"id":"pmh:oai:pure.atira.dk:publications/189c55ec-64d4-49e0-8bb4-17674f22ae4e","doi":null,"is_oa":true,"landing_page_url":"https://admin.research-repository.uwa.edu.au/en/publications/189c55ec-64d4-49e0-8bb4-17674f22ae4e","pdf_url":"http://research-repository.uwa.edu.au/en/publications/identification-and-characterisation-of-cat-allergens(189c55ec-64d4-49e0-8bb4-17674f22ae4e).html","source":{"id":"https://openalex.org/S4306402523","display_name":"UWA Profiles and Research Repository (University of Western Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"O'Neil, S 2013, 'Identification and characterisation of cat allergens', Doctor of Philosophy.","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://research-repository.uwa.edu.au/en/publications/identification-and-characterisation-of-cat-allergens(189c55ec-64d4-49e0-8bb4-17674f22ae4e).html","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090431585","display_name":"Serena O\u2019Neil","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Serena O\u2019Neil","raw_affiliation_strings":["School of Paediatrics and Child Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Paediatrics and Child Health","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5090431585"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cat-allergen","display_name":"cat allergen","score":0.9599999785423279},{"id":"https://openalex.org/keywords/fel-d-1","display_name":"Fel d 1","score":0.9359999895095825},{"id":"https://openalex.org/keywords/haptoglobin","display_name":"haptoglobin","score":0.8569999933242798},{"id":"https://openalex.org/keywords/ige-binding","display_name":"IgE binding","score":0.9079999923706055},{"id":"https://openalex.org/keywords/cat-allergy","display_name":"cat allergy","score":0.6899999976158142},{"id":"https://openalex.org/keywords/recombinant-allergen-expression","display_name":"recombinant allergen expression","score":0.847000002861023},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.7260000109672546},{"id":"https://openalex.org/keywords/s100a12","display_name":"S100A12","score":0.8100000023841858},{"id":"https://openalex.org/keywords/allergen-identification","display_name":"allergen identification","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6810433268547058},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3229535222053528},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23826190829277039},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:pure.atira.dk:publications/189c55ec-64d4-49e0-8bb4-17674f22ae4e","doi":null,"is_oa":true,"landing_page_url":"https://admin.research-repository.uwa.edu.au/en/publications/189c55ec-64d4-49e0-8bb4-17674f22ae4e","pdf_url":"http://research-repository.uwa.edu.au/en/publications/identification-and-characterisation-of-cat-allergens(189c55ec-64d4-49e0-8bb4-17674f22ae4e).html","source":{"id":"https://openalex.org/S4306402523","display_name":"UWA Profiles and Research Repository (University of Western Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"O'Neil, S 2013, 'Identification and characterisation of cat allergens', Doctor of Philosophy.","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2614739628","doi":null,"is_oa":false,"landing_page_url":"https://research-repository.uwa.edu.au/en/publications/identification-and-characterisation-of-cat-allergens(189c55ec-64d4-49e0-8bb4-17674f22ae4e).html","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pure.atira.dk:publications/189c55ec-64d4-49e0-8bb4-17674f22ae4e","doi":null,"is_oa":true,"landing_page_url":"https://admin.research-repository.uwa.edu.au/en/publications/189c55ec-64d4-49e0-8bb4-17674f22ae4e","pdf_url":"http://research-repository.uwa.edu.au/en/publications/identification-and-characterisation-of-cat-allergens(189c55ec-64d4-49e0-8bb4-17674f22ae4e).html","source":{"id":"https://openalex.org/S4306402523","display_name":"UWA Profiles and Research Repository (University of Western Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177877127","host_organization_name":"The University of Western Australia","host_organization_lineage":["https://openalex.org/I177877127"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"O'Neil, S 2013, 'Identification and characterisation of cat allergens', Doctor of Philosophy.","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2614739628.pdf","grobid_xml":"https://content.openalex.org/works/W2614739628.grobid-xml"},"referenced_works_count":154,"referenced_works":["https://openalex.org/W15990807","https://openalex.org/W73952711","https://openalex.org/W99562322","https://openalex.org/W1491052333","https://openalex.org/W1493122966","https://openalex.org/W1509319150","https://openalex.org/W1511503346","https://openalex.org/W1521548824","https://openalex.org/W1531361307","https://openalex.org/W1531584735","https://openalex.org/W1590790060","https://openalex.org/W1638763979","https://openalex.org/W1671888245","https://openalex.org/W1731104758","https://openalex.org/W1795543396","https://openalex.org/W1827073992","https://openalex.org/W1869212877","https://openalex.org/W1910526658","https://openalex.org/W1944374724","https://openalex.org/W1963778872","https://openalex.org/W1963916236","https://openalex.org/W1966081924","https://openalex.org/W1967362428","https://openalex.org/W1969912242","https://openalex.org/W1970336705","https://openalex.org/W1972185449","https://openalex.org/W1972950391","https://openalex.org/W1973153577","https://openalex.org/W1977919951","https://openalex.org/W1978147729","https://openalex.org/W1978388952","https://openalex.org/W1979223682","https://openalex.org/W1981614300","https://openalex.org/W1981714056","https://openalex.org/W1982130154","https://openalex.org/W1984493346","https://openalex.org/W1985757420","https://openalex.org/W1989270637","https://openalex.org/W1989310661","https://openalex.org/W1990154094","https://openalex.org/W1992035124","https://openalex.org/W1993379265","https://openalex.org/W1995069118","https://openalex.org/W1995999188","https://openalex.org/W1996423252","https://openalex.org/W1997354360","https://openalex.org/W1998094869","https://openalex.org/W1999039702","https://openalex.org/W2001268467","https://openalex.org/W2003254413","https://openalex.org/W2003371475","https://openalex.org/W2003937231","https://openalex.org/W2005179500","https://openalex.org/W2006155081","https://openalex.org/W2007294912","https://openalex.org/W2007945340","https://openalex.org/W2009021252","https://openalex.org/W2010220683","https://openalex.org/W2010606498","https://openalex.org/W2011137482","https://openalex.org/W2012682704","https://openalex.org/W2014169716","https://openalex.org/W2014471812","https://openalex.org/W2016138826","https://openalex.org/W2016565975","https://openalex.org/W2017057613","https://openalex.org/W2017199648","https://openalex.org/W2021656891","https://openalex.org/W2022737873","https://openalex.org/W2023295526","https://openalex.org/W2023896062","https://openalex.org/W2025160538","https://openalex.org/W2027439533","https://openalex.org/W2027873819","https://openalex.org/W2027902826","https://openalex.org/W2029406043","https://openalex.org/W2031676223","https://openalex.org/W2031820076","https://openalex.org/W2033779179","https://openalex.org/W2036563289","https://openalex.org/W2040141270","https://openalex.org/W2041254053","https://openalex.org/W2042604341","https://openalex.org/W2044482869","https://openalex.org/W2044928225","https://openalex.org/W2048179593","https://openalex.org/W2048398997","https://openalex.org/W2051133225","https://openalex.org/W2052742046","https://openalex.org/W2055043387","https://openalex.org/W2057763949","https://openalex.org/W2058095634","https://openalex.org/W2061739840","https://openalex.org/W2065354034","https://openalex.org/W2065483865","https://openalex.org/W2067222533","https://openalex.org/W2067605016","https://openalex.org/W2070938434","https://openalex.org/W2072495127","https://openalex.org/W2074525021","https://openalex.org/W2075342963","https://openalex.org/W2078654485","https://openalex.org/W2079869876","https://openalex.org/W2084399363","https://openalex.org/W2084696542","https://openalex.org/W2086520968","https://openalex.org/W2089724775","https://openalex.org/W2094201044","https://openalex.org/W2095806099","https://openalex.org/W2097211693","https://openalex.org/W2099053969","https://openalex.org/W2100837269","https://openalex.org/W2106684817","https://openalex.org/W2110445820","https://openalex.org/W2110681330","https://openalex.org/W2112010351","https://openalex.org/W2114294352","https://openalex.org/W2115884906","https://openalex.org/W2116029913","https://openalex.org/W2119412894","https://openalex.org/W2123636816","https://openalex.org/W2124723617","https://openalex.org/W2125324778","https://openalex.org/W2125767445","https://openalex.org/W2125851060","https://openalex.org/W2128303390","https://openalex.org/W2131861902","https://openalex.org/W2137450588","https://openalex.org/W2137575385","https://openalex.org/W2138366728","https://openalex.org/W2139237097","https://openalex.org/W2142155502","https://openalex.org/W2142740706","https://openalex.org/W2142854930","https://openalex.org/W2144906393","https://openalex.org/W2145304214","https://openalex.org/W2151497845","https://openalex.org/W2151686080","https://openalex.org/W2156202848","https://openalex.org/W2157070521","https://openalex.org/W2157824315","https://openalex.org/W2158308846","https://openalex.org/W2158567910","https://openalex.org/W2160699280","https://openalex.org/W2161279733","https://openalex.org/W2161938158","https://openalex.org/W2166685437","https://openalex.org/W2166698716","https://openalex.org/W2168847048","https://openalex.org/W2169150541","https://openalex.org/W2257315403","https://openalex.org/W2350325305","https://openalex.org/W2416064919","https://openalex.org/W4313310104"],"related_works":["https://openalex.org/W2048179593","https://openalex.org/W2016995998","https://openalex.org/W2022122272","https://openalex.org/W2022085964","https://openalex.org/W2162883956","https://openalex.org/W2016374544","https://openalex.org/W2070938434","https://openalex.org/W4388969361","https://openalex.org/W4413972080","https://openalex.org/W7055765317"],"abstract_inverted_index":{"[Truncated":[0],"abstract]":[1],"Background":[2],"While":[3],"cats":[4],"are":[5],"known":[6,146],"to":[7,35,53,70,89,140,196,227],"produce":[8],"at":[9],"least":[10],"10":[11],"allergenic":[12,270],"proteins,":[13],"only":[14],"Fel":[15,36,79,119,153,170,202,205,208,211,277],"d":[16,37,80,120,154,171,203,206,209,212,278],"1":[17,38],"has":[18],"been":[19],"extensively":[20],"characterised.":[21],"Recent":[22],"studies":[23],"have":[24,31],"shown":[25],"that":[26,323],"some":[27],"cat":[28,58,92,98,106,125,221,291,301,310],"allergic":[29,99,181,311],"subjects":[30,184,289],"high":[32,254],"IgE":[33,166,215,281,305],"binding":[34,167,198,216],"but":[39],"for":[40,175],"many":[41],"patients":[42],"the":[43,142,197,238,309,321,324],"titre":[44],"is":[45,52],"low.":[46],"The":[47,75,165,274,293,313],"purpose":[48],"of":[49,144,169,178,249,285,296,308,315],"this":[50],"study":[51],"identify":[54],"and":[55,60,84,161,173,182,194,214,225,260,266,303],"characterise":[56,71],"new":[57],"allergens,":[59],"determine":[61],"their":[62],"clinical":[63],"significance.":[64],"Methods":[65],"Several":[66],"methods":[67],"were":[68,122,185,223],"used":[69],"three":[72],"potential":[73],"allergens.":[74],"allergen":[76],"named":[77],"as":[78,326],"8":[81,155,172],"was":[82,103,156,298,318],"identified":[83],"produced":[85],"using":[86,131],"an":[87,233],"immunoassay":[88,192],"screen":[90],"a":[91,109,132,145,176,242,245],"mandibular":[93,239],"cDNA":[94,116,126,231],"library":[95,240],"with":[96,137,244,257,290],"human":[97],"sera.":[100],"Natural":[101],"haptoglobin":[102,174,297],"isolated":[104,123,224,236,299],"from":[105,124,180,232,237,288,300],"sera":[107,179,287],"by":[108,128,135,163,187,199,320],"procedure":[110],"based":[111],"on":[112],"ammonium":[113],"sulphate":[114],"precipitation.":[115],"clones":[117],"encoding":[118],"7":[121],"libraries":[127],"DNA":[129],"hybridisation":[130],"probe":[133],"made":[134],"PCR":[136],"primers":[138],"designed":[139],"amplify":[141],"homologue":[143],"dog":[147],"allergen,":[148],"Can":[149],"f":[150],"1.":[151],"Recombinant":[152],"expressed":[157],"in":[158,282,306],"Escherichia":[159],"coli":[160],"purified":[162],"chromatography.":[164],"activities":[168],"panel":[177],"non-allergic":[183],"determined":[186],"dissociation":[188],"enhanced":[189],"lanthanide":[190],"fluorescence":[191],"(DELFIA\u00ae)":[193],"compared":[195],"five":[200],"allergens;":[201],"1,":[204],"2,":[207],"3,":[210],"4":[213],"S100A12.":[217],"Results":[218],"Three":[219],"prospective":[220],"allergens":[222,317],"characterised":[226],"various":[228],"degrees.":[229],"A":[230],"IgE-reactive":[234],"clone":[235],"encoded":[241],"protein":[243,265,295],"predicted":[246],"molecular":[247],"mass":[248],"26":[250],"kDa.":[251],"It":[252],"had":[253],"sequence":[255],"identity":[256],"breast":[258],"cancer":[259],"salivary":[261],"gland":[262],"expression":[263],"gene":[264],"horse":[267,271],"latherin":[268],"(an":[269],"sweat":[272],"protein).":[273],"recombinant":[275],"polypeptide,":[276],"8,":[279],"bound":[280,304],"over":[283],"45%":[284],"78":[286],"allergy.":[292],"natural":[294],"serum":[302],"12%":[307],"subjects.":[312],"importance":[314],"these":[316],"demonstrated":[319],"finding":[322],"DELFIA\u00ae":[325]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2017-05-26T00:00:00"}
