{"id":"https://openalex.org/W2614337752","doi":null,"title":"Isolation and characterization of two distinct rainbow trout albumin genes","display_name":"Isolation and characterization of two distinct rainbow trout albumin genes","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W2614337752","mag":"2614337752"},"language":"en","primary_location":{"id":"pmh:oai:collectionscanada.gc.ca:OOAMICUS.19351902","doi":null,"is_oa":false,"landing_page_url":"http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0018/NQ27655.pdf","pdf_url":"http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0018/NQ27655.pdf","source":{"id":"https://openalex.org/S4306402307","display_name":"Library and Archives Canada (Government of Canada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2802286613","host_organization_name":"Government of Canada","host_organization_lineage":["https://openalex.org/I2802286613"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Electronic thesis or dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://utoronto.scholaris.ca/bitstreams/b4235d04-d88d-4178-8fed-029054d44bd4/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034880587","display_name":"Zhi Gong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Zhi Gong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5034880587"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.5737000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.5737000107765198,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.10019999742507935,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.06849999725818634,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rainbow-trout","display_name":"rainbow trout","score":0.9390000104904175},{"id":"https://openalex.org/keywords/albumin-gene","display_name":"albumin gene","score":0.8769999742507935},{"id":"https://openalex.org/keywords/albumin-promoter","display_name":"albumin promoter","score":0.6330000162124634},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/transcription-factor-binding-sites","display_name":"transcription factor binding sites","score":0.7139999866485596},{"id":"https://openalex.org/keywords/genomic-clones","display_name":"genomic clones","score":0.35499998927116394},{"id":"https://openalex.org/keywords/restriction-mapping","display_name":"restriction mapping","score":0.5899999737739563},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.4659999907016754},{"id":"https://openalex.org/keywords/site-directed-mutagenesis","display_name":"site-directed mutagenesis","score":0.6620000004768372},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.5410000085830688},{"id":"https://openalex.org/keywords/developmental-stages","display_name":"developmental stages","score":0.35600000619888306},{"id":"https://openalex.org/keywords/transcription-start-site","display_name":"transcription start sites","score":0.45899999141693115},{"id":"https://openalex.org/keywords/serum-albumin","display_name":"serum albumin","score":0.37299999594688416}],"concepts":[{"id":"https://openalex.org/C2994167347","wikidata":"https://www.wikidata.org/wiki/Q187986","display_name":"Rainbow trout","level":3,"score":0.8945962190628052},{"id":"https://openalex.org/C2775941552","wikidata":"https://www.wikidata.org/wiki/Q25212305","display_name":"Isolation (microbiology)","level":2,"score":0.6678275465965271},{"id":"https://openalex.org/C2776125364","wikidata":"https://www.wikidata.org/wiki/Q169219","display_name":"Albumin","level":2,"score":0.46079808473587036},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.414359986782074},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4035280644893646},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.35794222354888916},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3379785418510437},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.32802683115005493},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.2675115168094635},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2569285035133362},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.21114316582679749}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:collectionscanada.gc.ca:OOAMICUS.19351902","doi":null,"is_oa":false,"landing_page_url":"http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0018/NQ27655.pdf","pdf_url":"http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0018/NQ27655.pdf","source":{"id":"https://openalex.org/S4306402307","display_name":"Library and Archives Canada (Government of Canada)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2802286613","host_organization_name":"Government of Canada","host_organization_lineage":["https://openalex.org/I2802286613"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Electronic thesis or dissertation"},{"id":"pmh:oai:utoronto.scholaris.ca:1807/10578","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/10578","pdf_url":"https://utoronto.scholaris.ca/bitstreams/b4235d04-d88d-4178-8fed-029054d44bd4/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:2614337752","doi":null,"is_oa":false,"landing_page_url":"https://tspace.library.utoronto.ca/handle/1807/10578","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/10578","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/10578","pdf_url":"https://utoronto.scholaris.ca/bitstreams/b4235d04-d88d-4178-8fed-029054d44bd4/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320319880","display_name":"Government of Canada","ror":"https://ror.org/010q4q527"},{"id":"https://openalex.org/F4320323654","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2614337752.pdf","grobid_xml":"https://content.openalex.org/works/W2614337752.grobid-xml"},"referenced_works_count":118,"referenced_works":["https://openalex.org/W117186332","https://openalex.org/W200647492","https://openalex.org/W651223992","https://openalex.org/W1408783740","https://openalex.org/W1445320861","https://openalex.org/W1494228633","https://openalex.org/W1504792186","https://openalex.org/W1520020160","https://openalex.org/W1533583970","https://openalex.org/W1540845443","https://openalex.org/W1607008760","https://openalex.org/W1755110012","https://openalex.org/W1793177151","https://openalex.org/W1797059431","https://openalex.org/W1797540775","https://openalex.org/W1799486566","https://openalex.org/W1815280954","https://openalex.org/W1846817913","https://openalex.org/W1868383702","https://openalex.org/W1925053557","https://openalex.org/W1932076246","https://openalex.org/W1964980212","https://openalex.org/W1965258786","https://openalex.org/W1965372133","https://openalex.org/W1968169556","https://openalex.org/W1969452075","https://openalex.org/W1972808686","https://openalex.org/W1973238993","https://openalex.org/W1974481298","https://openalex.org/W1975045802","https://openalex.org/W1975131757","https://openalex.org/W1977565167","https://openalex.org/W1979028385","https://openalex.org/W1986664167","https://openalex.org/W1989481014","https://openalex.org/W1993912532","https://openalex.org/W1996099693","https://openalex.org/W2002886319","https://openalex.org/W2003027222","https://openalex.org/W2003184529","https://openalex.org/W2004026731","https://openalex.org/W2007804350","https://openalex.org/W2010016290","https://openalex.org/W2010452611","https://openalex.org/W2013249357","https://openalex.org/W2014201330","https://openalex.org/W2015502095","https://openalex.org/W2018682422","https://openalex.org/W2019719407","https://openalex.org/W2024036911","https://openalex.org/W2026131405","https://openalex.org/W2030794394","https://openalex.org/W2030896932","https://openalex.org/W2040653607","https://openalex.org/W2047262090","https://openalex.org/W2047842452","https://openalex.org/W2048356148","https://openalex.org/W2050128848","https://openalex.org/W2050808243","https://openalex.org/W2051181331","https://openalex.org/W2055435781","https://openalex.org/W2057007008","https://openalex.org/W2059640155","https://openalex.org/W2060761137","https://openalex.org/W2062423659","https://openalex.org/W2065014938","https://openalex.org/W2066215499","https://openalex.org/W2066465641","https://openalex.org/W2066790309","https://openalex.org/W2068577315","https://openalex.org/W2069471099","https://openalex.org/W2071888272","https://openalex.org/W2073865611","https://openalex.org/W2075682329","https://openalex.org/W2076134621","https://openalex.org/W2078945874","https://openalex.org/W2080153866","https://openalex.org/W2081495213","https://openalex.org/W2083105603","https://openalex.org/W2085383734","https://openalex.org/W2086242423","https://openalex.org/W2089275054","https://openalex.org/W2089597112","https://openalex.org/W2092191624","https://openalex.org/W2092359447","https://openalex.org/W2093033639","https://openalex.org/W2093371523","https://openalex.org/W2093680589","https://openalex.org/W2095138452","https://openalex.org/W2098919421","https://openalex.org/W2099240952","https://openalex.org/W2101127398","https://openalex.org/W2103786675","https://openalex.org/W2107115514","https://openalex.org/W2109170983","https://openalex.org/W2115276406","https://openalex.org/W2117969708","https://openalex.org/W2126093778","https://openalex.org/W2128635872","https://openalex.org/W2130577528","https://openalex.org/W2133335149","https://openalex.org/W2133887528","https://openalex.org/W2134812217","https://openalex.org/W2138015072","https://openalex.org/W2144634347","https://openalex.org/W2151087783","https://openalex.org/W2151097868","https://openalex.org/W2153037511","https://openalex.org/W2161659773","https://openalex.org/W2165218504","https://openalex.org/W2166372332","https://openalex.org/W2181175591","https://openalex.org/W2235700303","https://openalex.org/W2272478568","https://openalex.org/W2324955203","https://openalex.org/W2406626667","https://openalex.org/W2419294844","https://openalex.org/W2530506536"],"related_works":["https://openalex.org/W6903351691","https://openalex.org/W6980503467","https://openalex.org/W6921567915","https://openalex.org/W7027278262","https://openalex.org/W853137068","https://openalex.org/W4288094587","https://openalex.org/W144950766","https://openalex.org/W645504147","https://openalex.org/W6959699527","https://openalex.org/W2461849754"],"abstract_inverted_index":{"cette":[0,37],"th\u00e8se":[1,46],"sous":[2],"paper":[3],"or":[4,54],"electronic":[5],"formats.la":[6],"forme":[7],"de":[8,10,56],"microfiche/nlm,":[9],"reproduction":[11],"sur":[12,15],"papier":[13],"ou":[14,66],"format":[16],"\u00e9lectronique.The":[17],"author":[18],"retains":[19],"ownership":[20],"of":[21,75,99,114,118,132,139,142,148,162,175,185,195,203,210,217,226,253,259,268,273,299,308,313,319,326,329,337,344],"the":[22,32,64,100,115,193,196,204,211,230,245,260,274,287,369,384],"L'auteur":[23],"conserve":[24],"la":[25,45],"propri\u00e9t\u00e9":[26],"du":[27],"copyright":[28],"in":[29,109,244,322,340,373],"this":[30],"thesis.Neither":[31],"droit":[33],"d'auteur":[34],"qui":[35],"prot\u00e8ge":[36],"th\u00e8se.thesis":[38],"nor":[39],"substantial":[40],"extracts":[41],"fiom":[42],"it":[43],"Ni":[44],"ni":[47],"des":[48],"extraits":[49],"substantiels":[50],"may":[51],"be":[52],"printed":[53],"othemise":[55],"celle-ci":[57],"ne":[58],"doivent":[59],"\u00eatre":[60],"imprim\u00e9s":[61],"reproduced":[62],"without":[63],"author's":[65],"autrement":[67],"reproduits":[68],"sans":[69],"son":[70],"permission.autorisation.2-1":[71],"1.":[72],"Nothern":[73],"blot":[74],"rainbow":[76,90,133,167,276,330],"trout":[77,91,168,180,331],"total":[78],"RNA":[79],"from":[80],"different":[81],"developmental":[82],"stages":[83],"2-1":[84],"S.":[85],"In":[86],"situ":[87],"hybridization":[88,216,225],"on":[89,286],"embryos":[92],"witb":[93],"rtALB2":[94,104,122,205,221],"cDNA":[95],"77":[96],"2-13.Different":[97],"levels":[98],"rtALB":[101],"1":[102,120,129,262,294,301,355],"and":[103,121,152,189,316,347,376,381],"mRNA":[105],"2-14.The":[106],"probes":[107],"used":[108],"nuclear":[110,125],"run-on":[111,126],"experiment":[112],"2-15.Cornparison":[113],"transcriptional":[116],"rates":[117],"nALB":[119,261],"gene":[123,136,182,206,250,279],"by":[124],"assay":[127],"8":[128],"Two":[130],"hypothesis":[131],"mut":[134],"albumin":[135,181,269,278,310],"evolution":[137],"Smtegy":[138],"resaiction":[140],"mapping":[141,209],"genomic":[143,149,177,186,218,227,333],"DNA":[144,201,219,237],"clones":[145,178,187,334],"Restriction":[146],"maps":[147],"clone":[150,153,158,163],"4":[151,311],"16":[154],"Subclone":[155],"strateg":[156],"for":[157,166,179,240,366,377,391],"g16-5":[159],"Nested":[160],"deletions":[161],"g":[164],"16-5H2kSwtegy":[165],"aibumin\u00ee":[169],"promoter-CAT":[170],"construction":[171],"IO3":[172],"Southern":[173],"analysis":[174],"positive":[176],"Resrriction":[183],"rnapping":[184],"g4":[188],"g16":[190],"?CR":[191],"searching":[192],"location":[194],"nanscnption":[197],"stan":[198,213],"site":[199,214],"Partial":[200],"sequence":[202],"Primer":[207],"extention":[208],"mscripaon":[212],"Southem":[215,224],"with":[220,229],"cDKA":[222],"probe":[223,234],"DN.4":[228],"nALB2":[231],"5'":[232,246],"flanking":[233,247],"128":[235],"Potential":[236],"binding":[238],"sites":[239],"some":[241,320],"transcription":[242],"factors":[243],"region":[248],"oFnALB2":[249],"CAT":[251],"activities":[252],"albumin-CAT":[254],"constmcts":[255],"132":[256],"PCR":[257],"cloning":[258],"promoter":[263,293],"134":[264],"3-1":[265,282],"6.":[266],"Cornparison":[267],"promoten":[270],"3-17.Functiond":[271],"cornparison":[272],"two":[275],"uout":[277],"promoters":[280],"139":[281],"8.":[283],"Site-directed":[284],"mutations":[285],"r":[288],"~4":[289],"L":[290],"B":[291],"2":[292],"40":[295],"3-19.CATactivitiesof":[296],"mutants":[297],"List":[298],"Tables":[300],"-1.A":[302],"N":[303],"n":[304],"o":[305],"acid":[306],"composition":[307],"serum":[309],"2-1.Cornparison":[312],"silent":[314],"mutation":[315],"replacement":[317],"muration":[318],"genes":[321,349],"salmon":[323],"85":[324],"3-1.Sumrnary":[325],"southern":[327],"results":[328],"aibumin":[332],"109":[335],"3-2.Cornparison":[336],"cis":[338],"elements":[339],"proximal":[341],"prornoter":[342],"regions":[343],"ALB,":[345],"AFP.":[346],"DBP":[348],"v":[350],"i":[351,352],"Acknow":[353],"ledgments":[354],"would":[356],"like":[357],"to":[358,371,387,397],"thank":[359,389],"my":[360],"supervisor":[361],"Dr.":[362],"Choy":[363],"L.":[364],"Hew":[365],"giving":[367],"me":[368],"opponunity":[370],"work":[372],"his":[374,379,392],"laboratos.,":[375],"al1":[378],"guidance":[380],"suppon":[382],"over":[383],"years.I":[385],"wish":[386],"especially":[388],"him":[390],"encouragement":[393],"during":[394],"difficult":[395],"tirnes":[396],"make":[398]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2017-05-26T00:00:00"}