{"id":"https://openalex.org/W2613655741","doi":null,"title":"Ileal interposition for the treatment of diabetes in rats: repercussion on beta cells mass Tratamento do diabetes pela interposi\u00e7\u00e3o ileal em ratos: Repercuss\u00e3o na massa de c\u00e9lulas beta","display_name":"Ileal interposition for the treatment of diabetes in rats: repercussion on beta cells mass Tratamento do diabetes pela interposi\u00e7\u00e3o ileal em ratos: Repercuss\u00e3o na massa de c\u00e9lulas beta","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2613655741","mag":"2613655741"},"language":"pt","primary_location":{"id":"mag:2613655741","doi":null,"is_oa":false,"landing_page_url":"https://periodicos.ufrn.br/jscr/article/download/1421/1111","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021699673","display_name":"Layra Ribeiro de Sousa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Layra Ribeiro de Sousa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033100484","display_name":"A.A. Rasia Filho","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A.A. Rasia Filho","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019147683","display_name":"\u00cdtalo Medeiros Azevedo","orcid":"https://orcid.org/0000-0002-1507-7401","observed_orcids":["https://orcid.org/0000-0002-1507-7401"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00cdtalo Medeiros Azevedo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1507-7401","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107864299","display_name":"Mar\u00edlia Daniela Ferreira Carvalho","orcid":"https://orcid.org/0009-0008-1676-0748","observed_orcids":["https://orcid.org/0009-0008-1676-0748"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mar\u00edlia Daniela Ferreira Carvalho","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110284717","display_name":"Aldo Cunha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aldo Cunha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.8682000041007996,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.8682000041007996,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10569","display_name":"Bariatric Surgery and Outcomes","score":0.10320000350475311,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ileal-interposition","display_name":"ileal interposition","score":0.9760000109672546},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.878000020980835},{"id":"https://openalex.org/keywords/beta-cell-mass","display_name":"beta-cell mass","score":0.8230000138282776},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.7689999938011169},{"id":"https://openalex.org/keywords/c-peptide","display_name":"C-peptide","score":0.8360000252723694},{"id":"https://openalex.org/keywords/streptozotocin-induced-diabetes","display_name":"streptozotocin-induced diabetes","score":0.9160000085830688},{"id":"https://openalex.org/keywords/beta-cell-function","display_name":"beta-cell function","score":0.5450000166893005},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.8245940804481506},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7385009527206421},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6866900324821472},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6250892877578735},{"id":"https://openalex.org/C2776828364","wikidata":"https://www.wikidata.org/wiki/Q1767180","display_name":"Beta cell","level":4,"score":0.5917866230010986},{"id":"https://openalex.org/C2779280383","wikidata":"https://www.wikidata.org/wiki/Q257331","display_name":"Streptozotocin","level":3,"score":0.5805001854896545},{"id":"https://openalex.org/C2777226302","wikidata":"https://www.wikidata.org/wiki/Q233345","display_name":"Ileum","level":2,"score":0.5740140080451965},{"id":"https://openalex.org/C99476002","wikidata":"https://www.wikidata.org/wiki/Q42297","display_name":"Analysis of variance","level":2,"score":0.5129572749137878},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.5122372508049011},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.49634796380996704},{"id":"https://openalex.org/C2778875212","wikidata":"https://www.wikidata.org/wiki/Q419107","display_name":"C-peptide","level":3,"score":0.47041940689086914},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.4180545508861542},{"id":"https://openalex.org/C165220095","wikidata":"https://www.wikidata.org/wiki/Q207524","display_name":"Islet","level":3,"score":0.13350749015808105},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2613655741","doi":null,"is_oa":false,"landing_page_url":"https://periodicos.ufrn.br/jscr/article/download/1421/1111","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W200784466","https://openalex.org/W1970266771","https://openalex.org/W1977226383","https://openalex.org/W1984992349","https://openalex.org/W1997008557","https://openalex.org/W2001974771","https://openalex.org/W2002668094","https://openalex.org/W2007443428","https://openalex.org/W2022589777","https://openalex.org/W2032045122","https://openalex.org/W2063693981","https://openalex.org/W2064593977","https://openalex.org/W2071223877","https://openalex.org/W2073388607","https://openalex.org/W2077902771","https://openalex.org/W2080454816","https://openalex.org/W2088700722","https://openalex.org/W2102713533","https://openalex.org/W2102986473","https://openalex.org/W2110791445","https://openalex.org/W2114041992","https://openalex.org/W2127409471","https://openalex.org/W2140937253","https://openalex.org/W2142828362","https://openalex.org/W2143847100","https://openalex.org/W2145519915","https://openalex.org/W2146333376","https://openalex.org/W2149502431","https://openalex.org/W2157607499","https://openalex.org/W2170780334","https://openalex.org/W2184500611","https://openalex.org/W2195405554","https://openalex.org/W2398717042","https://openalex.org/W2415469310","https://openalex.org/W2613329981"],"related_works":["https://openalex.org/W230088416","https://openalex.org/W2074243204","https://openalex.org/W4232328428","https://openalex.org/W7097973351","https://openalex.org/W7120792127","https://openalex.org/W7120703589","https://openalex.org/W421844534","https://openalex.org/W2391258653","https://openalex.org/W2087208178","https://openalex.org/W2071315450"],"abstract_inverted_index":{"Purpose:":[0],"Research":[1],"with":[2,47,56,104],"the":[3,7,70,93,189,199,204,212],"aim":[4],"of":[5,9,34,52,89,101,167,206,214],"studying":[6],"effect":[8],"ileum":[10],"interposition":[11,49,106,134,180,201],"in":[12,19,114,132,143,160,178,184,218],"hyperglycemia":[13],"and":[14,45,84,169,188,209],"pancreatic":[15,158],"beta":[16,59,175,216],"cell":[17,60],"mass":[18,61,177,213],"nonobese":[20],"diabetic":[21,42,46,102,115,179,219],"rats.":[22,220],"Methods:":[23],"We":[24,80],"used":[25,81],"18":[26],"Wistar":[27],"rats":[28,117],"randomly":[29],"divided":[30],"into":[31],"3":[32],"groups":[33],"6":[35],"each.":[36],"A":[37],"non-diabetic":[38],"control":[39,43,116,144,185],"group,":[40,44],"a":[41,154,173],"ileal":[48,105,200],"group.":[50],"Induction":[51],"diabetes":[53,133,145,186],"was":[54,62,107,191],"underwent":[55],"streptozotocin.":[57],"The":[58,98,126,165,195],"quantified":[63],"by":[64,68],"an":[65],"indirect":[66],"method":[67],"dividing":[69],"serum":[71],"C-peptide":[72,127,168],"(ng/mL)":[73],"for":[74,87],"blood":[75,99,207],"glucose":[76,100,170,208],"(mg":[77],"/":[78,122,140,151],"dL).":[79],"variance":[82],"(ANOVA)":[83],"Tukey's":[85],"test":[86],"analysis":[88],"specific":[90],"differences,":[91],"considering":[92],"significance":[94],"p":[95],"<0.05.":[96],"Results:":[97],"animals":[103,181],"significantly":[108,130],"lower":[109],"(94.5":[110],"\u00b1":[111,119,137,148],"5.6mg/dL)":[112],"than":[113,142,183],"(245":[118],"4.8":[120],"mg":[121],"dL)":[123],"(p":[124,163],"<0.05).":[125,164],"levels":[128,171],"showed":[129,172,197],"higher":[131,174],"group":[135,146,162],"(0.58":[136],"0.06":[138],"ng":[139,150],"mL)":[141],"(0.42":[147],"0.03":[149],"mL),":[152],"suggesting":[153],"greater":[155],"response":[156],"to":[157,203,210],"stimulation":[159],"that":[161,198],"ratio":[166],"cells":[176,217],"(0.61)":[182],"(0.004),":[187],"difference":[190],"significant":[192],"(p<0.05).":[193],"Conclusion:":[194],"results":[196],"contributed":[202],"reduction":[205],"increase":[211],"functioning":[215]},"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2017-05-19T00:00:00"}