{"id":"https://openalex.org/W2609684457","doi":"https://doi.org/10.1038/nn.4549","title":"Identification of spinal circuits involved in touch-evoked dynamic mechanical pain","display_name":"Identification of spinal circuits involved in touch-evoked dynamic mechanical pain","publication_year":2017,"publication_date":"2017-04-24","ids":{"openalex":"https://openalex.org/W2609684457","doi":"https://doi.org/10.1038/nn.4549","mag":"2609684457","pmid":"https://pubmed.ncbi.nlm.nih.gov/28436981","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5470641"},"language":"en","primary_location":{"id":"doi:10.1038/nn.4549","doi":"https://doi.org/10.1038/nn.4549","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nn.4549","pdf_url":null,"source":{"id":"https://openalex.org/S2298632","display_name":"Nature Neuroscience","issn_l":"1097-6256","issn":["1097-6256","1546-1726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5470641","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018331396","display_name":"Longzhen Cheng","orcid":"https://orcid.org/0000-0003-2913-8428","observed_orcids":["https://orcid.org/0000-0003-2913-8428"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Longzhen Cheng","raw_affiliation_strings":["Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","Institute of Brain Science, the State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Institute of Brain Science, the State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022199777","display_name":"Bo Duan","orcid":"https://orcid.org/0000-0001-7915-8537","observed_orcids":["https://orcid.org/0000-0001-7915-8537"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bo Duan","raw_affiliation_strings":["Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","Present address: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Present address: Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.,","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055226277","display_name":"Tianwen Huang","orcid":"https://orcid.org/0000-0001-5039-6259","observed_orcids":["https://orcid.org/0000-0001-5039-6259"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tianwen Huang","raw_affiliation_strings":["Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yan Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100357981","display_name":"Wannan Medical College","ror":"https://ror.org/037ejjy86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I100357981"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yan Zhang","raw_affiliation_strings":["Cell Electrophysiology Laboratory, Wannan Medical College, Wuhu, China","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cell Electrophysiology Laboratory, Wannan Medical College, Wuhu, China","institution_ids":["https://openalex.org/I100357981"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100760188","display_name":"Yangyang Chen","orcid":"https://orcid.org/0009-0006-3864-1040","observed_orcids":["https://orcid.org/0009-0006-3864-1040"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yangyang Chen","raw_affiliation_strings":["Institute of Brain Science, the State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Brain Science, the State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067189468","display_name":"Olivier Britz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olivier Britz","raw_affiliation_strings":["Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","institution_ids":["https://openalex.org/I1307098950"]},{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028426585","display_name":"Lidia Garc\u00eda\u2010Campmany","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lidia Garcia-Campmany","raw_affiliation_strings":["Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","institution_ids":["https://openalex.org/I1307098950"]},{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiangyu Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiangyu Ren","raw_affiliation_strings":["Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","institution_ids":["https://openalex.org/I1307098950"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079375788","display_name":"Linh Vong","orcid":"https://orcid.org/0000-0003-2446-2624","observed_orcids":["https://orcid.org/0000-0003-2446-2624"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linh Vong","raw_affiliation_strings":["Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","Division of Endocrinology, Department of Medicine, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Endocrinology, Department of Medicine, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024782501","display_name":"Bradford B. Lowell","orcid":"https://orcid.org/0000-0002-0436-3760","observed_orcids":["https://orcid.org/0000-0002-0436-3760"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bradford B Lowell","raw_affiliation_strings":["Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","Division of Endocrinology, Department of Medicine, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Endocrinology, Department of Medicine, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090823484","display_name":"Martyn Goulding","orcid":"https://orcid.org/0000-0001-7950-409X","observed_orcids":["https://orcid.org/0000-0001-7950-409X"]},"institutions":[{"id":"https://openalex.org/I1307098950","display_name":"Salk Institute for Biological Studies","ror":"https://ror.org/03xez1567","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1307098950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martyn Goulding","raw_affiliation_strings":["Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, California, USA","institution_ids":["https://openalex.org/I1307098950"]},{"raw_affiliation_string":"Molecular Neurobiology Laboratory, the Salk Institute for Biological Studies, La Jolla, USA","institution_ids":["https://openalex.org/I1307098950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100377608","display_name":"Yun Wang","orcid":"https://orcid.org/0000-0002-0369-9895","observed_orcids":["https://orcid.org/0000-0002-0369-9895"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yun Wang","raw_affiliation_strings":["Institute of Brain Science, the State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Brain Science, the State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048316523","display_name":"Qiufu Ma","orcid":"https://orcid.org/0000-0001-7896-7914","observed_orcids":["https://orcid.org/0000-0001-7896-7914"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qiufu Ma","raw_affiliation_strings":["Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Dana-Farber Cancer Institute and Department of Neurobiology, Harvard Medical School, Boston, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5048316523","https://openalex.org/A5100377608"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I24943067","https://openalex.org/I4210117453","https://openalex.org/I4391768195"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":15.1622,"has_fulltext":false,"cited_by_count":240,"citation_normalized_percentile":{"value":0.9953208,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"20","issue":"6","first_page":"804","last_page":"814"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mechanical-hypersensitivity","display_name":"mechanical hypersensitivity","score":0.8119999766349792},{"id":"https://openalex.org/keywords/vesicular-glutamate-transporter-3","display_name":"VGLUT3","score":0.890999972820282},{"id":"https://openalex.org/keywords/lbx1","display_name":"Lbx1","score":0.9959999918937683},{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.7789999842643738},{"id":"https://openalex.org/keywords/somatostatin-neurons","display_name":"somatostatin neurons","score":0.7490000128746033},{"id":"https://openalex.org/keywords/lamina-i","display_name":"lamina I","score":0.6620000004768372},{"id":"https://openalex.org/keywords/nerve-injury","display_name":"nerve injury","score":0.5590000152587891},{"id":"https://openalex.org/keywords/place-aversion","display_name":"place aversion","score":0.5509999990463257},{"id":"https://openalex.org/keywords/genetic-ablation","display_name":"gene ablation","score":0.4359999895095825},{"id":"https://openalex.org/keywords/chronic-pain","display_name":"chronic pain","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6940193772315979},{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.6615247130393982},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5427470803260803},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.5310445427894592},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.4948500990867615},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.44859445095062256},{"id":"https://openalex.org/C2775991916","wikidata":"https://www.wikidata.org/wiki/Q2945973","display_name":"Nerve injury","level":2,"score":0.43649280071258545},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43469658493995667},{"id":"https://openalex.org/C2781118164","wikidata":"https://www.wikidata.org/wiki/Q1088113","display_name":"Chronic pain","level":2,"score":0.4160967469215393},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2666458785533905},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.17028799653053284},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11637493968009949},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09337300062179565},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001362","descriptor_name":"Avoidance Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003024","descriptor_name":"Clozapine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004167","descriptor_name":"Diphtheria Toxin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006930","descriptor_name":"Hyperalgesia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009020","descriptor_name":"Morphine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013004","descriptor_name":"Somatostatin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014110","descriptor_name":"Touch","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D026922","descriptor_name":"Amino Acid Transport Systems, Acidic","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D026922","descriptor_name":"Amino Acid Transport Systems, Acidic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D026922","descriptor_name":"Amino Acid Transport Systems, Acidic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D036421","descriptor_name":"Nerve Fibers, Unmyelinated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055879","descriptor_name":"Gene Knock-In Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066257","descriptor_name":"Heparin-binding EGF-like Growth Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/nn.4549","doi":"https://doi.org/10.1038/nn.4549","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nn.4549","pdf_url":null,"source":{"id":"https://openalex.org/S2298632","display_name":"Nature Neuroscience","issn_l":"1097-6256","issn":["1097-6256","1546-1726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Neuroscience","raw_type":"journal-article"},{"id":"pmid:28436981","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28436981","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4567724","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5470641","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5470641","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5470641","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Neurosci","raw_type":"Text"},{"id":"pmh:oai:dash.harvard.edu:1/34492288","doi":null,"is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:34492288","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4567724","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5470641","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1107783668","display_name":"Boston Area Diabetes Endocrinology Research Center","funder_award_id":"P30DK057521","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G1877067353","display_name":"TRP Channel Mediated Pain Circuitry","funder_award_id":"P01NS072040","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G1937724381","display_name":"Intersectional genetic dissection of spinal circuits processing pain and itch","funder_award_id":"R01NS086372","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G2046174560","display_name":"The AgRP / POMC -> Paraventricular (PVH) -> Parabrachial (PBN) -> Limbic/Reward Satiety Circuit","funder_award_id":"R01DK075632","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2559176377","display_name":"Leptin, GABAergic Neurons and the Feedback / Feedforward Regulation of Energy Balance","funder_award_id":"R01DK089044","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3711098856","display_name":"Boston Nutrition Obesity Research Center","funder_award_id":"P30DK046200","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3791694075","display_name":"Salk Institute for Biological Studies NINDS Center Core Grant","funder_award_id":"P30NS072031","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4230694460","display_name":"Genetic Control of Nociceptive Sensory Neuron Development and Pain Behavior","funder_award_id":"R01DE018025","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G6485454692","display_name":"Glutamatergic Neurons in the Arcuate Nucleus (ARC) and Regulation of Satiety","funder_award_id":"R01DK111401","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6882940710","display_name":"AgRP neurons: circadian control and interactions with the HPA axis","funder_award_id":"R01DK096010","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W1546041226","https://openalex.org/W1969751124","https://openalex.org/W1969918990","https://openalex.org/W1974527199","https://openalex.org/W1978406271","https://openalex.org/W1978678518","https://openalex.org/W1978803477","https://openalex.org/W1987895705","https://openalex.org/W1988722797","https://openalex.org/W1993608941","https://openalex.org/W1995572733","https://openalex.org/W1999460576","https://openalex.org/W2003542915","https://openalex.org/W2008205503","https://openalex.org/W2008543586","https://openalex.org/W2012265686","https://openalex.org/W2014779151","https://openalex.org/W2015386261","https://openalex.org/W2018459912","https://openalex.org/W2020705596","https://openalex.org/W2022898812","https://openalex.org/W2026910668","https://openalex.org/W2031811175","https://openalex.org/W2033571114","https://openalex.org/W2033980432","https://openalex.org/W2036459878","https://openalex.org/W2036804461","https://openalex.org/W2037172320","https://openalex.org/W2040574649","https://openalex.org/W2047010161","https://openalex.org/W2047615113","https://openalex.org/W2058605577","https://openalex.org/W2059635921","https://openalex.org/W2061077377","https://openalex.org/W2063223361","https://openalex.org/W2063428082","https://openalex.org/W2064698198","https://openalex.org/W2068692900","https://openalex.org/W2068996358","https://openalex.org/W2073940113","https://openalex.org/W2078187429","https://openalex.org/W2092112296","https://openalex.org/W2092211307","https://openalex.org/W2104135721","https://openalex.org/W2115568736","https://openalex.org/W2132809690","https://openalex.org/W2134557769","https://openalex.org/W2140910583","https://openalex.org/W2141005071","https://openalex.org/W2145718412","https://openalex.org/W2150013759","https://openalex.org/W2151214732","https://openalex.org/W2152963050","https://openalex.org/W2169382112","https://openalex.org/W2177655369","https://openalex.org/W2220753543","https://openalex.org/W2315232423","https://openalex.org/W2511651422","https://openalex.org/W2564777270"],"related_works":["https://openalex.org/W1969751124","https://openalex.org/W7097124076","https://openalex.org/W7029052956","https://openalex.org/W4387676073","https://openalex.org/W1617368976","https://openalex.org/W2003269271","https://openalex.org/W2336842431","https://openalex.org/W2132809690","https://openalex.org/W7147326831","https://openalex.org/W2961172235"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":22},{"year":2025,"cited_by_count":28},{"year":2024,"cited_by_count":36},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":37},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":22},{"year":2019,"cited_by_count":29},{"year":2018,"cited_by_count":21},{"year":2017,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2017-05-05T00:00:00"}