{"id":"https://openalex.org/W2609010682","doi":"https://doi.org/10.3389/fcimb.2017.00136","title":"Eutirucallin: A Lectin with Antitumor and Antimicrobial Properties","display_name":"Eutirucallin: A Lectin with Antitumor and Antimicrobial Properties","publication_year":2017,"publication_date":"2017-04-25","ids":{"openalex":"https://openalex.org/W2609010682","doi":"https://doi.org/10.3389/fcimb.2017.00136","mag":"2609010682","pmid":"https://pubmed.ncbi.nlm.nih.gov/28487845","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5403948"},"language":"en","primary_location":{"id":"doi:10.3389/fcimb.2017.00136","doi":"https://doi.org/10.3389/fcimb.2017.00136","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcimb.2017.00136","pdf_url":"https://www.frontiersin.org/articles/10.3389/fcimb.2017.00136/pdf","source":{"id":"https://openalex.org/S2506667490","display_name":"Frontiers in Cellular and Infection Microbiology","issn_l":"2235-2988","issn":["2235-2988"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular and Infection Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fcimb.2017.00136/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042946939","display_name":"Julio G. Palharini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Julio G. Palharini","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061824463","display_name":"Aline Richter","orcid":"https://orcid.org/0000-0001-6385-153X","observed_orcids":["https://orcid.org/0000-0001-6385-153X"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Aline C. Richter","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064894969","display_name":"Mariana Ferreira Silva","orcid":"https://orcid.org/0000-0002-9034-3650","observed_orcids":["https://orcid.org/0000-0002-9034-3650"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Mariana F. Silva","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","Laboratory of Tumor Biomarkers and Osteoimmunology, Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndiaUberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]},{"raw_affiliation_string":"Laboratory of Tumor Biomarkers and Osteoimmunology, Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndiaUberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108590181","display_name":"Fl\u00e1via Batista Ferreira","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Flavia B. Ferreira","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038660019","display_name":"Carlos Priminho Pirovani","orcid":"https://orcid.org/0000-0002-6176-4069","observed_orcids":["https://orcid.org/0000-0002-6176-4069"]},"institutions":[{"id":"https://openalex.org/I3122449915","display_name":"Universidade Estadual de Santa Cruz","ror":"https://ror.org/01zwq4y59","country_code":"BR","type":"education","lineage":["https://openalex.org/I3122449915"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carlos P. Pirovani","raw_affiliation_strings":["Biological Sciences Department, State University of Santa Cruz, Ilh\u00e9us, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biological Sciences Department, State University of Santa Cruz, Ilh\u00e9us, Brazil","institution_ids":["https://openalex.org/I3122449915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038580890","display_name":"Karinne Spirandelli Carvalho Naves","orcid":"https://orcid.org/0000-0001-5648-0144","observed_orcids":["https://orcid.org/0000-0001-5648-0144"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Karinne S. C. Naves","raw_affiliation_strings":["Laboratory of Clinical Bacteriology, Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Bacteriology, Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005448275","display_name":"Vivian Alonso\u2010Goulart","orcid":"https://orcid.org/0000-0002-2041-0053","observed_orcids":["https://orcid.org/0000-0002-2041-0053"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vivian A. Goulart","raw_affiliation_strings":["Laboratory of Nanobiotechnology, Institute of Genetics and Biochemistry, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Nanobiotechnology, Institute of Genetics and Biochemistry, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007040642","display_name":"Tiago Wilson Patriarca Mineo","orcid":"https://orcid.org/0000-0002-2339-2743","observed_orcids":["https://orcid.org/0000-0002-2339-2743"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tiago W. P. Mineo","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015485121","display_name":"Marcelo Jos\u00e9 Barbosa Silva","orcid":"https://orcid.org/0000-0002-5807-4286","observed_orcids":["https://orcid.org/0000-0002-5807-4286"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcelo J. B. Silva","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndiaUberl\u00e2ndia, Brazil","Laboratory of Tumor Biomarkers and Osteoimmunology, Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndiaUberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]},{"raw_affiliation_string":"Laboratory of Tumor Biomarkers and Osteoimmunology, Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086189505","display_name":"Fernanda Maria Santiago","orcid":"https://orcid.org/0000-0002-6204-0863","observed_orcids":["https://orcid.org/0000-0002-6204-0863"]},"institutions":[{"id":"https://openalex.org/I80850581","display_name":"Universidade Federal de Uberl\u00e2ndia","ror":"https://ror.org/04x3wvr31","country_code":"BR","type":"education","lineage":["https://openalex.org/I80850581"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Fernanda M. Santiago","raw_affiliation_strings":["Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunoparasitology \"Dr. Mario Endsfeldz Camargo\", Institute of Biomedical Sciences, Federal University of Uberl\u00e2ndia, Uberl\u00e2ndia, Brazil","institution_ids":["https://openalex.org/I80850581"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5086189505"],"corresponding_institution_ids":["https://openalex.org/I80850581"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":1.7819,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.8353744,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"7","issue":null,"first_page":"136","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.6122999787330627,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.6122999787330627,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.2694999873638153,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13185","display_name":"Phytochemistry and Bioactive Compounds","score":0.022600000724196434,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lectins","display_name":"lectins","score":0.7509999871253967},{"id":"https://openalex.org/keywords/euphorbia-tirucalli","display_name":"Euphorbia tirucalli","score":0.9509999752044678},{"id":"https://openalex.org/keywords/latex","display_name":"LaTeX","score":0.7419999837875366},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9629999995231628},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8270000219345093},{"id":"https://openalex.org/keywords/antiparasitic-activity","display_name":"antiparasitic activity","score":0.9769999980926514},{"id":"https://openalex.org/keywords/toxoplasma-gondii","display_name":"Toxoplasma gondii","score":0.8479999899864197},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8069999814033508},{"id":"https://openalex.org/keywords/hemagglutination","display_name":"hemagglutination","score":0.8479999899864197},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.7710000276565552},{"id":"https://openalex.org/keywords/cancer-cell-lines","display_name":"cancer cell lines","score":0.6679999828338623},{"id":"https://openalex.org/keywords/ehrlich-ascites-carcinoma","display_name":"Ehrlich ascites carcinoma","score":0.9520000219345093},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.7129999995231628},{"id":"https://openalex.org/keywords/protein-stability","display_name":"protein stability","score":0.3869999945163727}],"concepts":[{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.8353660106658936},{"id":"https://openalex.org/C2777366897","wikidata":"https://www.wikidata.org/wiki/Q847482","display_name":"HeLa","level":3,"score":0.7732093334197998},{"id":"https://openalex.org/C2776197502","wikidata":"https://www.wikidata.org/wiki/Q25326666","display_name":"Ehrlich ascites carcinoma","level":3,"score":0.733711302280426},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.7315043807029724},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6470018625259399},{"id":"https://openalex.org/C2780758401","wikidata":"https://www.wikidata.org/wiki/Q408693","display_name":"Lectin","level":2,"score":0.6292450428009033},{"id":"https://openalex.org/C2781421772","wikidata":"https://www.wikidata.org/wiki/Q581102","display_name":"Antiparasitic","level":2,"score":0.6187090873718262},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.615869402885437},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6124642491340637},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.510249137878418},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.5082773566246033},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5000042915344238},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3877756893634796},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26850664615631104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08364349603652954},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000890","descriptor_name":"Anti-Infective Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000977","descriptor_name":"Antiparasitic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001938","descriptor_name":"Brazil","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002286","descriptor_name":"Carcinoma, Ehrlich Tumor","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004355","descriptor_name":"Drug Stability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004926","descriptor_name":"Escherichia coli","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006384","descriptor_name":"Hemagglutination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014122","descriptor_name":"Toxoplasma","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014123","descriptor_name":"Toxoplasmosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D028481","descriptor_name":"Euphorbia","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D037121","descriptor_name":"Plant Lectins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D037121","descriptor_name":"Plant Lectins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061986","descriptor_name":"MCF-7 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.3389/fcimb.2017.00136","doi":"https://doi.org/10.3389/fcimb.2017.00136","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcimb.2017.00136","pdf_url":"https://www.frontiersin.org/articles/10.3389/fcimb.2017.00136/pdf","source":{"id":"https://openalex.org/S2506667490","display_name":"Frontiers in Cellular and Infection Microbiology","issn_l":"2235-2988","issn":["2235-2988"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular and Infection Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4270755","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5403948","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:5403948","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5403948","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cell Infect Microbiol","raw_type":"Text"},{"id":"pmid:28487845","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28487845","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cellular and infection microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.gla.ac.uk:318808","doi":null,"is_oa":false,"landing_page_url":"https://eprints.gla.ac.uk/318808/1/318808.pdf","pdf_url":"https://eprints.gla.ac.uk/318808/1/318808.pdf","source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/I4405259220","host_organization_name":"Institut Agama Islam Negeri Langsa","host_organization_lineage":["https://openalex.org/I4405259220"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Articles"},{"id":"pmh:oai:doaj.org/article:fa88ea5e0f574bc88c041a2e7ebdb533","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/fa88ea5e0f574bc88c041a2e7ebdb533","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fcimb.2017.00136","doi":"https://doi.org/10.3389/fcimb.2017.00136","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fcimb.2017.00136","pdf_url":"https://www.frontiersin.org/articles/10.3389/fcimb.2017.00136/pdf","source":{"id":"https://openalex.org/S2506667490","display_name":"Frontiers in Cellular and Infection Microbiology","issn_l":"2235-2988","issn":["2235-2988"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular and Infection Microbiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.766700029373169,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1942937696","display_name":null,"funder_award_id":"AUX-PE-Parasitologia-1348/2011","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G2943947938","display_name":"REDE DE PESQUISA EM DOEN\u00c7AS INFECCIOSAS HUMANAS E ANIMAIS DO ESTADO DE MINAS GERAIS","funder_award_id":"RED-00013-14","funder_id":"https://openalex.org/F4320322980","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais"},{"id":"https://openalex.org/G2946678644","display_name":null,"funder_award_id":"CDSRED00013-14","funder_id":"https://openalex.org/F4320322980","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais"},{"id":"https://openalex.org/G32729727","display_name":null,"funder_award_id":"CVZ-PPM-00784-15","funder_id":"https://openalex.org/F4320322980","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais"},{"id":"https://openalex.org/G4463787961","display_name":null,"funder_award_id":"309011/2013-2","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"},{"id":"https://openalex.org/G6522156980","display_name":null,"funder_award_id":"RED-00013-14","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G7580221470","display_name":null,"funder_award_id":"RED-00013-14","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"},{"id":"https://openalex.org/G7909075137","display_name":"PADR\u00c3O INFLAMAT\u00d3RIO DIFERENCIAL ENTRE AS INFEC\u00c7\u00d5ES INDUZIDAS PELOS PROTOZO\u00c1RIOS TOXOPLASMA GONDII E NEOSPORA CANINUM","funder_award_id":"PPM-00784-15","funder_id":"https://openalex.org/F4320322980","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais"},{"id":"https://openalex.org/G8957162110","display_name":null,"funder_award_id":"CDS-RED-00013-14, CVZ-PPM-00784-15","funder_id":"https://openalex.org/F4320322980","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais"}],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322980","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","ror":"https://ror.org/00nc55f03"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2609010682.pdf","grobid_xml":"https://content.openalex.org/works/W2609010682.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W169207685","https://openalex.org/W1540578549","https://openalex.org/W1646986055","https://openalex.org/W1803102843","https://openalex.org/W1880828415","https://openalex.org/W1899668346","https://openalex.org/W1938551807","https://openalex.org/W1963684604","https://openalex.org/W1964851083","https://openalex.org/W1966827627","https://openalex.org/W1969727726","https://openalex.org/W1971818484","https://openalex.org/W1972831517","https://openalex.org/W1980691330","https://openalex.org/W1987484892","https://openalex.org/W1987590780","https://openalex.org/W1988989929","https://openalex.org/W1993925272","https://openalex.org/W1996528284","https://openalex.org/W1998340266","https://openalex.org/W2008022325","https://openalex.org/W2009499719","https://openalex.org/W2010656683","https://openalex.org/W2018289835","https://openalex.org/W2022695112","https://openalex.org/W2024551447","https://openalex.org/W2034480139","https://openalex.org/W2039094071","https://openalex.org/W2039811087","https://openalex.org/W2049865787","https://openalex.org/W2051265367","https://openalex.org/W2056389789","https://openalex.org/W2059994793","https://openalex.org/W2060938552","https://openalex.org/W2061294496","https://openalex.org/W2065337529","https://openalex.org/W2066005032","https://openalex.org/W2068584243","https://openalex.org/W2072865927","https://openalex.org/W2073722456","https://openalex.org/W2074748801","https://openalex.org/W2078176299","https://openalex.org/W2082992597","https://openalex.org/W2086019616","https://openalex.org/W2090361935","https://openalex.org/W2096449359","https://openalex.org/W2100837269","https://openalex.org/W2108221597","https://openalex.org/W2113660655","https://openalex.org/W2114918609","https://openalex.org/W2126188187","https://openalex.org/W2128635872","https://openalex.org/W2134565257","https://openalex.org/W2135142065","https://openalex.org/W2135751151","https://openalex.org/W2146847355","https://openalex.org/W2149694154","https://openalex.org/W2155481598","https://openalex.org/W2157510372","https://openalex.org/W2158080844","https://openalex.org/W2160521615","https://openalex.org/W2293937432","https://openalex.org/W2314643415","https://openalex.org/W2415985114","https://openalex.org/W2467615155","https://openalex.org/W6638459692","https://openalex.org/W6641812284","https://openalex.org/W6642833976","https://openalex.org/W6647758476","https://openalex.org/W6662880261","https://openalex.org/W6665638738","https://openalex.org/W6674859433","https://openalex.org/W6676122346","https://openalex.org/W6682178368","https://openalex.org/W6683097355","https://openalex.org/W6683365469","https://openalex.org/W6720441005"],"related_works":["https://openalex.org/W2996674839","https://openalex.org/W1969750288","https://openalex.org/W2501937653","https://openalex.org/W7097737501","https://openalex.org/W4403728245","https://openalex.org/W4406440644","https://openalex.org/W4400515994","https://openalex.org/W4411239205","https://openalex.org/W2967180833","https://openalex.org/W3124638124"],"abstract_inverted_index":{"Eutirucallin":[0,25,36,60,84,98,106],"is":[1],"a":[2,11,50],"lectin":[3],"isolated":[4],"from":[5,39],"the":[6,86],"latex":[7],"of":[8,24,101,128],"Euphorbia":[9],"tirucalli,":[10],"plant":[12],"known":[13],"for":[14,64,76,125],"its":[15],"medical":[16],"properties.":[17],"The":[18],"present":[19],"study":[20,122],"explores":[21],"various":[22],"characteristics":[23],"including":[26],"stability,":[27],"cytotoxicity":[28],"against":[29,114],"tumor":[30,70],"cells,":[31],"antimicrobial":[32],"and":[33,53,68,82,92],"antiparasitic":[34],"activities.":[35],"was":[37,73,94],"stable":[38],"2":[40],"to":[41,108],"40":[42],"days":[43],"at":[44,57],"4oC,":[45],"maintained":[46],"hemagglutinating":[47],"activity":[48,56,63],"within":[49],"restricted":[51],"range,":[52],"showed":[54,107],"optimal":[55],"pH":[58],"7.0-8.0.":[59],"presented":[61],"antiproliferative":[62],"HeLa,":[65],"PC3,":[66],"MDA-MB-231":[67],"MCF-7":[69],"cells":[71,78],"but":[72],"not":[74],"cytotoxic":[75],"non-tumorigenic":[77],"such":[79],"as":[80],"macrophages":[81],"fibroblasts.":[83],"inhibited":[85,99],"Ehrlich":[87],"ascites":[88],"carcinoma":[89],"in":[90,118],"vivo":[91],"it":[93],"also":[95],"observed":[96],"that":[97],"62.5%":[100],"Escherichia":[102],"coli":[103],"growth.":[104],"Also,":[105],"be":[109],"effective":[110],"when":[111],"tested":[112],"directly":[113],"Toxoplasma":[115],"gondii":[116],"infection":[117],"vitro.":[119],"Therefore,":[120],"this":[121],"sheds":[123],"perspectives":[124],"pharmacological":[126],"applications":[127],"Eutirucallin.":[129]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2017-05-05T00:00:00"}