{"id":"https://openalex.org/W260760173","doi":null,"title":"Phase III Clinical Trial of Revaprazan (Revanex\uff1f) for Gastritis","display_name":"Phase III Clinical Trial of Revaprazan (Revanex\uff1f) for Gastritis","publication_year":2006,"publication_date":"2006-10-01","ids":{"openalex":"https://openalex.org/W260760173","mag":"260760173"},"language":"en","primary_location":{"id":"pmh:oai:ir.ymlib.yonsei.ac.kr:22282913/110919","doi":null,"is_oa":true,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","pdf_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","source":{"id":"https://openalex.org/S4306400691","display_name":"YUHSpace (Yonsei University Medical Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193775966","host_organization_name":"Yonsei University","host_organization_lineage":["https://openalex.org/I193775966"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"T200603825.pdf","raw_type":"Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075345859","display_name":"Myung\u2010Gyu Choi","orcid":"https://orcid.org/0000-0003-4083-5187","observed_orcids":["https://orcid.org/0000-0003-4083-5187","https://orcid.org/0000-0002-7297-6577"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Myung\u2010Gyu Choi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4083-5187","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041019402","display_name":"Soo\u2010Heon Park","orcid":"https://orcid.org/0000-0003-3056-8740","observed_orcids":["https://orcid.org/0000-0003-3056-8740"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soo\u2010Heon Park","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3056-8740","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064728609","display_name":"Sung Kook Kim","orcid":"https://orcid.org/0000-0002-2861-8123","observed_orcids":["https://orcid.org/0000-0002-2861-8123","https://orcid.org/0000-0001-8281-3379"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sung Kook Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Rin Chang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rin Chang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111789250","display_name":"Seok Reyol Choi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seok Reyol Choi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070006828","display_name":"Geun Am Song","orcid":"https://orcid.org/0000-0003-2100-8522","observed_orcids":["https://orcid.org/0000-0003-2100-8522"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geun Am Song","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2100-8522","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059751861","display_name":"Ki Baik Hahm","orcid":"https://orcid.org/0000-0002-2971-7166","observed_orcids":["https://orcid.org/0000-0002-2971-7166"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ki Baik Hahm","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2971-7166","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085725295","display_name":"Yong Chan Lee","orcid":"https://orcid.org/0000-0001-8800-6906","observed_orcids":["https://orcid.org/0000-0001-8800-6906"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yong Chan Lee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8800-6906","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108586922","display_name":"Hyun Soo Kim","orcid":"https://orcid.org/0000-0001-5572-5453","observed_orcids":["https://orcid.org/0000-0001-5572-5453"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hyun Soo Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033232152","display_name":"Tae Nyeun Kim","orcid":"https://orcid.org/0000-0003-4178-2056","observed_orcids":["https://orcid.org/0000-0003-4178-2056"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tae Nyeun Kim","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4178-2056","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019652970","display_name":"Suck Chei Choi","orcid":"https://orcid.org/0000-0003-1338-3306","observed_orcids":["https://orcid.org/0000-0003-1338-3306"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Suck Chei Choi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1338-3306","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014535577","display_name":"Sang Yong Seol","orcid":"https://orcid.org/0000-0003-4525-9916","observed_orcids":["https://orcid.org/0000-0003-4525-9916"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sang Yong Seol","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4525-9916","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002851078","display_name":"Jong Sun Rew","orcid":"https://orcid.org/0000-0002-6405-9656","observed_orcids":["https://orcid.org/0000-0002-6405-9656"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jong Sun Rew","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6405-9656","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100617949","display_name":"Dong Joon Kim","orcid":"https://orcid.org/0000-0002-7035-087X","observed_orcids":["https://orcid.org/0000-0002-7035-087X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dong Joon Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100327057","display_name":"Jin Yong Lee","orcid":"https://orcid.org/0000-0002-6039-2224","observed_orcids":["https://orcid.org/0000-0002-6039-2224","https://orcid.org/0000-0002-5698-5561"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jin Lee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6039-2224","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075017758","display_name":"Ho Soon Choi","orcid":"https://orcid.org/0000-0003-3746-8742","observed_orcids":["https://orcid.org/0000-0003-3746-8742"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ho Soon Choi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3746-8742","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110055414","display_name":"Ju Yeon Jeong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ju Yeon Jeong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061249927","display_name":"Geun Seog Song","orcid":"https://orcid.org/0000-0001-6080-2572","observed_orcids":["https://orcid.org/0000-0001-6080-2572"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Geun Seog Song","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6080-2572","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109184215","display_name":"Byoung Seok Moon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Byoung Seok Moon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5006475848","display_name":"Sang Aun Joo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sang Aun Joo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"33","issue":"4","first_page":"212","last_page":"219"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.8359000086784363,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.8359000086784363,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.13379999995231628,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ranitidine","display_name":"ranitidine","score":0.8429999947547913},{"id":"https://openalex.org/keywords/gastritis","display_name":"gastritis","score":0.8199999928474426},{"id":"https://openalex.org/keywords/acute-gastritis","display_name":"acute gastritis","score":0.7839999794960022},{"id":"https://openalex.org/keywords/h2-receptor-antagonists","display_name":"H2 receptor antagonists","score":0.8370000123977661},{"id":"https://openalex.org/keywords/proton-pump-inhibitors","display_name":"proton pump inhibitors","score":0.6980000138282776},{"id":"https://openalex.org/keywords/endoscopic-improvement","display_name":"endoscopic improvement","score":0.703000009059906},{"id":"https://openalex.org/keywords/symptom-improvement","display_name":"symptom improvement","score":0.8880000114440918},{"id":"https://openalex.org/keywords/comparative-efficacy","display_name":"drug efficacy comparison","score":0.7400000095367432},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.9369999766349792}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9615192413330078},{"id":"https://openalex.org/C2777445857","wikidata":"https://www.wikidata.org/wiki/Q423037","display_name":"Ranitidine","level":2,"score":0.9287706613540649},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.6230505704879761},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6140428185462952},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5817546844482422},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.563522219657898},{"id":"https://openalex.org/C2778451229","wikidata":"https://www.wikidata.org/wiki/Q212809","display_name":"Endoscopy","level":2,"score":0.47152575850486755},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.4599302411079407},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.4384562075138092},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.1396627128124237}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ir.ymlib.yonsei.ac.kr:22282913/110919","doi":null,"is_oa":true,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","pdf_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","source":{"id":"https://openalex.org/S4306400691","display_name":"YUHSpace (Yonsei University Medical Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193775966","host_organization_name":"Yonsei University","host_organization_lineage":["https://openalex.org/I193775966"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"T200603825.pdf","raw_type":"Article"},{"id":"mag:260760173","doi":null,"is_oa":false,"landing_page_url":"https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART001028389","pdf_url":null,"source":{"id":"https://openalex.org/S2755109226","display_name":"Clinical Endoscopy","issn_l":"2234-2400","issn":["2234-2400","2234-2443"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","kci-registered","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4324113237","host_organization_name":"Korean Society of Gastrointestinal Endoscopy","host_organization_lineage":["https://openalex.org/P4324113237"],"host_organization_lineage_names":["Korean Society of Gastrointestinal Endoscopy"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Clinical Endoscopy","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ir.ymlib.yonsei.ac.kr:22282913/110919","doi":null,"is_oa":true,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","pdf_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/110919","source":{"id":"https://openalex.org/S4306400691","display_name":"YUHSpace (Yonsei University Medical Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193775966","host_organization_name":"Yonsei University","host_organization_lineage":["https://openalex.org/I193775966"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"T200603825.pdf","raw_type":"Article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W260760173.pdf","grobid_xml":"https://content.openalex.org/works/W260760173.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7072270119","https://openalex.org/W194770969","https://openalex.org/W1543787997","https://openalex.org/W1966354090","https://openalex.org/W172835842","https://openalex.org/W2063448572","https://openalex.org/W6918129","https://openalex.org/W7098200732","https://openalex.org/W2132750554","https://openalex.org/W2884662660"],"abstract_inverted_index":{"Background/Aims:":[0],"We":[1],"performed":[2],"a":[3,21,110,139],"randomized,":[4],"double-blind,":[5],"phase":[6],"III,":[7],"multicenter":[8],"trial":[9],"to":[10,51,77,194],"assess":[11],"the":[12,72,80,85,89,116,121,124,143,148,161,165,169,189,199,209],"comparative":[13],"efficacy":[14,69,82,179],"and":[15,37,46,79,106,130,134,196,203],"safety":[16],"of":[17,40,54,168,180,186],"revaprazan,":[18],"which":[19],"is":[20],"novel":[22],"acid":[23],"pump":[24],"antagonist":[25],"in":[26,142],"comparison":[27],"with":[28,34,56,104,108,212],"ranitidine":[29,63,131,187],"for":[30,88,128,164,188,198],"treating":[31],"patients":[32],"suffering":[33,211],"acute":[35,38],"gastritis":[36],"aggravation":[39],"chronic":[41],"gastritis.":[42,213],"\\nMethods:":[43],"Five":[44],"hundred":[45],"twelve":[47],"subjects":[48,210],"were":[49,102,132,156,174],"randomized":[50],"2":[52,98],"weeks":[53,99],"treatment":[55],"either":[57],"revaprazan":[58,105,129,181,204],"200":[59],"mg":[60,65],"q.d.":[61],"or":[62],"150":[64],"b.i.d.":[66],"The":[67,93,178],"primary":[68],"parameter":[70,83],"was":[71,84,113,138,182,205],"estimated":[73,94,125,144,190],"improvement":[74,86,95,126,145,166,191,201],"rate":[75,87,192],"according":[76,193],"endoscopy,":[78],"secondary":[81],"subjects'":[90,170],"symptoms.":[91,171],"\\nResults:":[92],"rates":[96,127,146,167],"at":[97],"(intention-to-treat":[100],"analysis)":[101],"79.9%":[103],"60.5%":[107],"ranitidine;":[109],"significant":[111,140,158],"difference":[112,141],"found":[114],"between":[115,147,160],"two":[117,149,162],"groups":[118,150,163],"(p\u7aca\ufffd0.0001).":[119,151],"On":[120,152],"per-protocol":[122],"analysis,":[123],"79.4%":[133],"60.2%,":[135],"respectively.":[136],"There":[137],"both":[153],"analyses,":[154],"there":[155],"no":[157],"differences":[159],"Both":[172],"drugs":[173],"well":[175,206],"tolerated.":[176],"\\nConclusions:":[177],"higher":[183],"than":[184],"that":[185],"endoscopy":[195],"also":[197],"symptomatological":[200],"rate,":[202],"tolerated":[207],"by":[208]},"counts_by_year":[{"year":2023,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}